Paeg005347.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Pararge aegeria
Gene Symbol
Hr39
Assembly
GCA_905163445.1
Location
NC:4403797-4476447[-]

Transcription Factor Domain

TF Family
SF-like
Domain
zf-C4|SF-like
PFAM
AnimalTFDB
TF Group
Zinc-Coordinating Group
Description
The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 3 2 1.3e+04 -5.5 10.9 49 170 187 311 123 356 0.54
2 3 2.9e-08 0.00019 20.5 0.1 1 21 437 457 437 468 0.91
3 3 2.6e-65 1.7e-61 208.4 0.0 152 408 490 755 465 755 0.83

Sequence Information

Coding Sequence
ATGATGTCGACGAGCGAGGGTGAGGCTGTGAAAGTGGAGGGGGGGCATGTCTCCGTCACAACCATTAGTATGTCGGGTCCAGAGACCAGCAATGGTCGTTTCTCGTACAGTTCTAGCGGCGTACGCATCAGTGTGTCTTCCGAGCCACACGATGAAGACTCCACGGATGCCGAAATCTCGAAAATCGACTTCACACAGCACCAATATGAGGTAAACATGCGAAACAAAAAGAAGCGATCGTCCAGCGGGCAGTACGACCAGGCTGTCGAGCAGGAGAGGCCGATGTCTTGGGAGGGCGAGCTGTCAGACTCCGAGATGGTCATCGATACCAGTGTAAACAACGATGAGAACAGCAGCTCCCTCGATCTGCAATCGTCGCGCGATTCCATAGACACACTGCGTAATGTGACCATAAAGACGGAACCTCTCAAAACCGAAGCCTTCCAGAGTTTGGACGACCAGCGTGTTCTAGATCTAAAATACACTGTACCATTGCAGTCGCACCAACGGAGTCTTAGTATGAACAGGATATCAGTGCTAGCAGACAACGCATCGCTGACTCTGGCTAGGCGGCCATCTTCTCCCATGAGCAGTGCCAAATCAGCCCACTCCGACCAATATGAATCGCCCCTAGCGCATAACCCGAATATCGAAGTTCAGAACTTGACCATCAAGAAAGAGACGCTTTCTGAGCTGAAGTGTGAACCATCGATGAGCATGGACAAGTTACTGGGGCTGCACGGATCACCTTTGCTTGGCCGCCTGCCGAGAGTACAGTCCAGTGCCAGCACCGACTCTGCCGTACATTCTATGTACACGCATAGCGTATACAGCAGTCCATCAGCCAGCCCTCGACCGTCGAGGCATTATACGCCGTCTCTTTCTCGCAACAACAGCGACGCTTCTCACTCATCGTGCTATTCCTACAGCTCGGAGTTCTCGCCTACACATTCACCAGTACAGAGTCGACATCCACACGTAGTATACCGAGAAGCAACCGTGTTCCCGGCGTCACCCGCACACGATGAGGACACTGATACGACCGACGATCGACTCCATCATCACCAGGGCATCAGTAGGCAGCAACTGATCAACAGCCCTTGTCCAATCTGCGGTGACAAGATCAGCGGTTTCCACTACGGTATATTCTCTTGCGAGTCTTGCAAAGGTTTCTTCAAGCGGACAGTTCAGAATCGCAAGAACTACATGTGTCTAAGAGGAGGAAATTGCCCAGTAACTGTTGCTACTCGCAAAAAGTGCCCCGCTTGTCGGTTCGACAAGTGTTTGGGTTGCGGAATGAAGCTCGAAGCGATAAGGGAAGACAGAACTCGCGGAGGTCGCTCGACGTATCAGTGTTCATATACACTGTCTGGTGCCGCGTCTACAGGTTCGTTGCTCTCTGCGCATGCGCCAACCACGCTCCGGCACGCATCCAGCCTCACTTGCGTAAATGGCCCTGGGTCGTATAGCAGTCGAGGAGAATCAAGTAACAGCCGACTCACGCCTGACATACCCCCATTATTGCAGGAAATAATGGATGTGGAACATTTATGGCAATACAACGAGTCAGAGCTGAGCCGCATGAGCAAGTCCACCGGCAGTCCGTCCGCGAACCCCCTACTGGCCGCCAGCGGGATTACTGCACAGAACTCCAGTGCGGACTTCCTTGCGGACCTGTGCAACATCGCGGACCATCGGCTGTACAAAATAGTCAAGTGGTGCAAGAGTCTGCCCCTTTTCAAGAATATTTcgATCGACGACCAGATCTGTTTGCTGATCAACAGCTGGTGTGAATTGCTGGTGCTTTCCTGCTGCTACCGCGGGGTCAGCACTCCGGGAGAAGTTCGTGTTGGGGGAGGCCGGGGAATCACCCTTCATCAAAGTGCCAAATATGGTCTGACGCCTTGTATAGAACGAATGCTCAGCTTCACCGACCATTTGAGGAGGCTACGAGTCGACCGATACGAATATGTTGCGCTCAAGGTCATTGTCCTTCTCACTTCAGaTGCTCCCGAACTTCGAGAAGCGGAGAAGGTACGAGCTTCGCAAGAAAAAGCGCTTGCAGCGCTGCAAGCGTATACCGCAGCTCACTCGCCAGATACGCCGGCTAAGTTTGGGGAACTTTTGCTGCGTATCCCCGAGCTGCAACGAACTTGCCAgTTCTTCATGCAAGTCGGCAAGGAAATGCTCAACCCCGCCAACAAGGGCAAGGACGGTGAAGGTCCCAGTTTCAACCTCTTGATGGAGCTCTTGAGGGGCGACCACTAA
Protein Sequence
MMSTSEGEAVKVEGGHVSVTTISMSGPETSNGRFSYSSSGVRISVSSEPHDEDSTDAEISKIDFTQHQYEVNMRNKKKRSSSGQYDQAVEQERPMSWEGELSDSEMVIDTSVNNDENSSSLDLQSSRDSIDTLRNVTIKTEPLKTEAFQSLDDQRVLDLKYTVPLQSHQRSLSMNRISVLADNASLTLARRPSSPMSSAKSAHSDQYESPLAHNPNIEVQNLTIKKETLSELKCEPSMSMDKLLGLHGSPLLGRLPRVQSSASTDSAVHSMYTHSVYSSPSASPRPSRHYTPSLSRNNSDASHSSCYSYSSEFSPTHSPVQSRHPHVVYREATVFPASPAHDEDTDTTDDRLHHHQGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYMCLRGGNCPVTVATRKKCPACRFDKCLGCGMKLEAIREDRTRGGRSTYQCSYTLSGAASTGSLLSAHAPTTLRHASSLTCVNGPGSYSSRGESSNSRLTPDIPPLLQEIMDVEHLWQYNESELSRMSKSTGSPSANPLLAASGITAQNSSADFLADLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLVLSCCYRGVSTPGEVRVGGGRGITLHQSAKYGLTPCIERMLSFTDHLRRLRVDRYEYVALKVIVLLTSDAPELREAEKVRASQEKALAALQAYTAAHSPDTPAKFGELLLRIPELQRTCQFFMQVGKEMLNPANKGKDGEGPSFNLLMELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00985246;
90% Identity
iTF_01018623;
80% Identity
iTF_01151302;