Basic Information

Insect: Papilio xuthus
Gene Symbol: foxj1b
Assembly: GCA_000836235.1
Location: NW:313867-315333[-]

Transcription Factor Domain

TF Family: Fork_head
Domain: Fork_head domain
PFAM: PF00250
TF Group: Helix-turn-helix
Description: The fork head domain is a conserved DNA-binding domain (also known as a winged helix) of about 100 amino-acid residues. Drosophila melanogaster fork head protein is a transcription factor that promotes terminal rather than segmental development, contains neither homeodomains nor zinc-fingers characteristic of other transcription factors [1]. Instead, it contains a distinct type of DNA-binding region, containing around 100 amino acids, which has since been identified in a number of transcription factors (including D. melanogaster FD1-5, mammalian HNF-3, human HTLF, Saccharomyces cerevisiae HCM1, etc.). This is referred to as the fork head domain but is also known as a 'winged helix' [1, 2, 3]. The fork head domain binds B-DNA as a monomer [2], but shows no similarity to previously identified DNA-binding motifs. Although the domain is found in several different transcription factors, a common function is their involvement in early developmental decisions of cell fates during embryogenesis [3].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 2.5 1.6e+03 -1.1 0.1 55 75 20 40 18 47 0.79

2 3 1.8e-36 1.2e-33 114.8 0.4 2 83 353 433 352 438 0.97

3 3 2.2 1.4e+03 -0.9 0.0 37 52 444 458 433 471 0.69

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	2.5	1.6e+03	-1.1	0.1	55	75	20	40	18	47	0.79
2	3	1.8e-36	1.2e-33	114.8	0.4	2	83	353	433	352	438	0.97
3	3	2.2	1.4e+03	-0.9	0.0	37	52	444	458	433	471	0.69

Sequence Information

Coding Sequence: atGTTTGACAATTCTAAATTTGATAGGAATGAAGAGGCTGGTCTCGAGAAAGATTTTTTAGAATTGGAAGATAAATTCAGCAAGATTGAAGACtggaaaaataattcaagaaagggattttctaataattacaATCCGCCACGTTTAGATGCGGAAAATTCAGCAGGTAATGGCCATTTAAGGACTTATCTTAATACTTTTGAAAATGATTACGAACCTTTTAATGTTCAAGAGCCAAATTTTAATGGTCGATCTACAAGAAGTTTAAGTGTGGCTGAtgccaaaaataatatttctcatCGATTTCTAGAACCAGGTGTgttccaaaatatttcttctggAATATACCAAGAACAAGATTTCAGAGAAAAGGCGGGATCTTTCTCTTCTTccaataattcaaaattagatAATCTAAAAAATGAAGAGATATTAAATCAAGttgataaattagaaaataatgagtttaaaaaggaattaaaaggAGGAAGACCTTTAAATACATCTTATAACTGTTATAAACCTAATTCATTTGAATCTCAAAAACAAATGTACAGTGTAAACCGACCAGCTGGTTCGTGTTTGTTTAAAACGCCtcctttctttaaaaatgcgTACGTTGAAAAGAATTCACCACAAAATTGTGGTCCAATGTCACCACCAATGATCCCaattaatcaatttgaaaATCAAGAAAGACCAGTAAATTCAACGATGTTTATTCCTGATCAGAACTCATCGTATGGATTTATGCCTTATAAGATCATTGAGAAAGATATTATACAATCTAATAGTGTTTATATGAATCGTAATCTACCACCAAGTCCATTTAACACTTTTggttcaatttataaaagaagatcGTATTCAGAAGCAGATCTTAGTAAAAGTAGAAGTAAAATTAGAAACAATTTTGATAATGATGAAGATTTAAtgactttatataaaaaaggaaagtTTAGTAGATCATCTTCAGAAAGTTGTATTGATCCAAGGacgttttataaaacagaaaatttcCCGAGAGTATTTCAAACCAACAAAGAAAACCTTGCAAAACCAAGTCATTCCTATGCACAAATCATCACTCGTGCAATTTCAAGTAGCCAAGACGGTAAGCTTTCCCTTGGTGAGATATACAAATGGATAgaagaaaattttgaatattatagaTACGCTAATCCAGTTTGGAAAAATTCTATTCGTCACAATTTGTCgttaagtaaatgttttaagaaagTTCCTAGAGAACCAGGTAGTCGAGGAAAAGGCGGTAAGTGGATGATAGATAAAGagtatttgtttattgaagaaagtaaaaagaaacgGAGATCTTATGGTGAAGAAAATGAGACCTTTCAGAACAGTAtcgataaaaaagatatttgtaatGAAGGATATTTACGAAATAATATCACAACTGTTGAGTATTCGAGTTATGGCGAAAGTAAATACgaagaaatgtaa
Protein Sequence: MFDNSKFDRNEEAGLEKDFLELEDKFSKIEDWKNNSRKGFSNNYNPPRLDAENSAGNGHLRTYLNTFENDYEPFNVQEPNFNGRSTRSLSVADAKNNISHRFLEPGVFQNISSGIYQEQDFREKAGSFSSSNNSKLDNLKNEEILNQVDKLENNEFKKELKGGRPLNTSYNCYKPNSFESQKQMYSVNRPAGSCLFKTPPFFKNAYVEKNSPQNCGPMSPPMIPINQFENQERPVNSTMFIPDQNSSYGFMPYKIIEKDIIQSNSVYMNRNLPPSPFNTFGSIYKRRSYSEADLSKSRSKIRNNFDNDEDLMTLYKKGKFSRSSSESCIDPRTFYKTENFPRVFQTNKENLAKPSHSYAQIITRAISSSQDGKLSLGEIYKWIEENFEYYRYANPVWKNSIRHNLSLSKCFKKVPREPGSRGKGGKWMIDKEYLFIEESKKKRRSYGEENETFQNSIDKKDICNEGYLRNNITTVEYSSYGESKYEEM

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01149395;
90% Identity: iTF_01149393;
80% Identity: -