Basic Information

Gene Symbol
che-1
Assembly
GCA_018231625.1
Location
DVQH01002036.1:10139-10489[-]

Transcription Factor Domain

TF Family
zf-GAGA
Domain
zf-GAGA domain
PFAM
PF09237
TF Group
Zinc-Coordinating Group
Description
Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 4 0.0054 1.4e+02 4.2 0.1 27 44 11 28 8 32 0.90
2 4 5.8e-05 1.5 10.5 0.4 21 45 33 57 28 61 0.87
3 4 0.0009 24 6.7 0.3 21 51 61 91 57 92 0.85
4 4 4.6e-07 0.012 17.2 0.3 21 45 89 113 85 115 0.90

Sequence Information

Coding Sequence
AtgactttaataaatatcaaactCGACAGGTGCAATATCTGTGCGAAAGCATTCTCGCAAGCGGCCAATCTGACGGCCCACATACGAACACACAGTGGGGAAAAGCCATTTCCGTGTCCGGTGTGTCATCGGCGCTTTTCGCAGTCCTCCTCGGTCACCACTCACCTGCGGACTCACTCGGGCGAGCGTCCCTACTGTTGCAGCTACTGTCGCAAAGCCTTCTCCGACTCCTCCACTCTCACCAAGCATCTACGAATTCACTCGGGCGAAAAGCCATACCAGTGTCAAATGTGTTATCTTCGTTTTTCTCAATCCGGCAACTTGAATCGTCACATGCGCATCCATGGGTAG
Protein Sequence
MTLINIKLDRCNICAKAFSQAANLTAHIRTHSGEKPFPCPVCHRRFSQSSSVTTHLRTHSGERPYCCSYCRKAFSDSSTLTKHLRIHSGEKPYQCQMCYLRFSQSGNLNRHMRIHG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01146657;
90% Identity
iTF_01146657;
80% Identity
iTF_01146657;