Pdem009174.1
Basic Information
- Insect
- Papilio demoleus
- Gene Symbol
- Litaf
- Assembly
- GCA_029286655.1
- Location
- JAGSMY010000012.1:5650460-5652155[+]
Transcription Factor Domain
- TF Family
- zf-LITAF-like
- Domain
- zf-LITAF-like domain
- PFAM
- PF10601
- TF Group
- Zinc-Coordinating Group
- Description
- Members of this family display a conserved zinc ribbon structure [3] with the motif C-XX-C- separated from the more C-terminal HX-C(P)X-C-X4-G-R motif by a variable region of usually 25-30 (hydrophobic) residues. Although it belongs to one of the zinc finger's fold groups (zinc ribbon), this particular domain was first identified in LPS-induced tumour necrosis alpha factor (LITAF) which is produced in mammalian cells after being challenged with lipopolysaccharide (LPS)[2]. The hydrophobic region probably inserts into the membrane rather than traversing it. Such an insertion brings together the N- and C-terminal C-XX-C motifs to form a compact Zn2+-binding structure [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 1 1.6e-26 5.3e-23 81.5 15.4 2 69 56 124 55 125 0.95
Sequence Information
- Coding Sequence
- ATGGGTCTGCCACCTCCGTATGAACCAAGCCCACCGAACCCTGCGCCACCGCCATCGTACTTCGGTGATAACCCCCCACCACCCGCGGCTACCACTCAGCCTCGCACAGTTGTCGTGACCAACGCACCTACGTCATCCGATAGCAGTGACATTAAAATAGGACCGGGGCCAACAGGCATAACCTGCCCCAACTGCAACAGATCCGTCGTCACACGAGTGCACTATGCGGCTAACAATAGAACACATATTATATCAGCTGGACTTTGTATATTAACAGGatgCTGTTGCGGTTGCTTCGTACCCTACTGCATGCGATCTTGTAAATCAGCGAACCATTTTTGTCCTAAATGTAGAGCGTTCATTGGTACATACGCACCTTCTTGA
- Protein Sequence
- MGLPPPYEPSPPNPAPPPSYFGDNPPPPAATTQPRTVVVTNAPTSSDSSDIKIGPGPTGITCPNCNRSVVTRVHYAANNRTHIISAGLCILTGCCCGCFVPYCMRSCKSANHFCPKCRAFIGTYAPS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01496205;
- 90% Identity
- iTF_01140612; iTF_01147778; iTF_00197797; iTF_01147109; iTF_01142092; iTF_01143535; iTF_01139344; iTF_01144979; iTF_01145651; iTF_01130484; iTF_01150038; iTF_00250135; iTF_01142807; iTF_01149246; iTF_01148511;
- 80% Identity
- -