Osur017793.1
Basic Information
- Insect
- Oryzaephilus surinamensis
- Gene Symbol
- MBD-R2_1
- Assembly
- GCA_004796505.1
- Location
- SSSI01002577.1:719-1453[+]
Transcription Factor Domain
- TF Family
- MBD
- Domain
- MBD domain
- PFAM
- PF01429
- TF Group
- Unclassified Structure
- Description
- The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 2 0.73 3.4e+03 -2.2 0.1 38 45 22 29 20 31 0.83 2 2 1.2e-19 5.5e-16 58.0 0.0 7 73 120 185 114 189 0.94
Sequence Information
- Coding Sequence
- ACTTATGAAGTATTATTTGATGATGGTTTTATGAAAACATTAAAGGCGCACAGAATGAGCAAACCGCAAGGGAAAACTTTACAATCGTCACCATTATTCGATCCAGTCAAAGGTACGAAGCAAGAACGTCGCGAAAAGAAACGCAAATTGAATGTGGCagcattatttaataaaaaacgtcAACGTACTGACAATTATGAAACGAAAACAAAGGATACTTCAAGTCCAGGAACACCAACAACATTATCAGAAGATGATTCACAACAATATATCATAAAGTGGGAAAATGGACGACCAATTGGTAAAGAATCGTTCATTGATACATTGGATGGTACGAAACGGGCATCGGTCGTCATTGATGATCCACGTTTATTGCCTGGATGGgaaaaacattttgtacaaCGTCAGTTGGGCAGTTCGGCTGGCAAATGGGATTGTGTATTTGTTAGTCCAGATAATAGACGATTTAGAAGCAAAGCGGAAATTCGTACATATTTCGAATCGCATCCAGAACATAGTTATGTTGAAGGTATGTTTGACTTTAGTACTGGTCGtggtaaaaatataaaacggtTGGACAACAAAAAAACTAGTATTGTTAATACTGAAGTTGAAACAAATGAACCAATGGTTGAAGTTAAAATGGAACAAGTTGAGGACATAAAAGAGTCTGAAG
- Protein Sequence
- TYEVLFDDGFMKTLKAHRMSKPQGKTLQSSPLFDPVKGTKQERREKKRKLNVAALFNKKRQRTDNYETKTKDTSSPGTPTTLSEDDSQQYIIKWENGRPIGKESFIDTLDGTKRASVVIDDPRLLPGWEKHFVQRQLGSSAGKWDCVFVSPDNRRFRSKAEIRTYFESHPEHSYVEGMFDFSTGRGKNIKRLDNKKTSIVNTEVETNEPMVEVKMEQVEDIKESE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -