Obor002497.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Oryctes borbonicus
Gene Symbol
kel
Assembly
GCA_902654985.1
Location
LR736877.1:2418777-2423466[-]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 2.6e-34 7.7e-32 109.7 2.2 1 109 69 174 69 175 0.95

Sequence Information

Coding Sequence
ATGGACATCGATCGAGACTTGCGAGAGGGATCTTGCGATCTTGAACGTGATATTCCAATGGAGAGACAGGGAAGTTGCTTGTTACTACGTTATGCTAGTCAGAACTCGCTTGACGAAAGCTCACAGAAACATGTTCCAAGACCAAACAGCAAAGATAAACCACCATATCGAAATAATCATCATACACATCGAGCGTTTGATGTTATGAACCATATGAGACAAGAATTACTTTTGTGCGATGTTACTTTGATAGCTGATAACGTTGAGATACCAGCTCATAAGATGGTGTTGGCTGCTTGTTCACCCTATTTCTATGCGATGTTTACAAGTTTCGAGGAAAGTAAACAAGATAAGATTACGCTTAAAGAAATAGATAGTACAGCTCTTACTTTATTAGTCGAATATGTTTATACATCCGAAGTGCAAGTAACAGAAGAAAATGTGCAAgtATTGTTACCAGCGGCAAATCTGTTGCAATTAACTGATGTTCGTGATGCTTGCTGCGATTTCTTGCAAGCTCAACTTCATCCATCGAATTGTCTGGGTATTAGAGCATTTGCTGACTTACATGGTTGCCTTGACTTGTTGAATAGTGCGGAAAGTTATATCGAACTACATTTTCCGGAGGTGGTTGAGTGTGAAGAATTTTTAACTTTGTCGCATCAACAAGTTGCTAAGTTAATATGCAGTGATAGATTAACGGTACCTTCAGAAGAAAAGGTTTTCGAATGTGTGATAGCATGGGTTCAGCATGATTTAAAACATAGGCAAGAACATCTTTCGGCTTTAATGGAACATGTGCGGTTGCCTTTGATGTCTCAAGAGTACTTGGTCCAACGAGTTGAAGAAGAACCTTTATTGAAAGCCGATCTTCattgtaaagattttattatcgaagctttaaaatatcatttattgaAAGGTGACTTGAAGACTTGCATCAAGACGCCGAGGACTAAGCCAAGGCAACCTGTTGGTTTACCGAAAgtattGCTAGTAGTTGGTGGTCAAGCTCCAAAAGCAATTAGAAGCGTAGAATGTTACGATTTCAAAGAAGAACGATGGTATCAAGTAGCTGAGATGCCAACTAGACGCTGCAGGGCTGGACTTGCTGTTATTAATGGCAAGGTTTATGCGGTAGGCGGATTTAACGGTTCGCTTAGGGTTAGAACGGTCGATGTCTACGATGCGTCCTTAGATCAATGGAGTAGTTGCGCCAATATGGAAGCTAGACGGTCAACGTTGGGTGTGGCGGTGTTAGGAAATTGTATTTATGCAGTTGGCGGCTTTGACGGATCGACCGGATTGAATACAGCTGAAAAATTCGATCCTAGAACGCAGGAGTGGAGTACCATTTCAGCTATGTCTACTAGGAGGAGTAGTGTTGGTGTTGGAGTGTTGCATAATTTGTTGTATGCTGTTGGTGGTTATGATGGTGCTTCAAGGCAATGTTTAAGCTCTGTAGAATGTTACAATCCAGAAACTAATACTTGGACATCTGTAGCGGATATGAGTTCTCGCCGAAGTGGTGCTGGTGTTGGAGTATTAGACGGCATCTTATATGCTGTTGGTGGCCACGATGGTCCTCTAGTCAGGAAATCGGTTGAAGCTTACAACTCCGAAACTGGAACTTGGACTTCTGTTAATGACATGGCTTTATGCAGGAGAAACGCAGGCGTTGTAGCTATGAACAACTTATTGTATGTCGTGGGAGGTGATGATGGTTCAAGTAATTTAGCTTCAGTGGAAGTGTACAATCCTAAAACTGAGTCGTGGACGATGTTACCTAGTTGTATGAGCATTGGACGTAGTTATGCTGGTGTGGCAATTATAGACAAACCCATTTGA
Protein Sequence
MDIDRDLREGSCDLERDIPMERQGSCLLLRYASQNSLDESSQKHVPRPNSKDKPPYRNNHHTHRAFDVMNHMRQELLLCDVTLIADNVEIPAHKMVLAACSPYFYAMFTSFEESKQDKITLKEIDSTALTLLVEYVYTSEVQVTEENVQVLLPAANLLQLTDVRDACCDFLQAQLHPSNCLGIRAFADLHGCLDLLNSAESYIELHFPEVVECEEFLTLSHQQVAKLICSDRLTVPSEEKVFECVIAWVQHDLKHRQEHLSALMEHVRLPLMSQEYLVQRVEEEPLLKADLHCKDFIIEALKYHLLKGDLKTCIKTPRTKPRQPVGLPKVLLVVGGQAPKAIRSVECYDFKEERWYQVAEMPTRRCRAGLAVINGKVYAVGGFNGSLRVRTVDVYDASLDQWSSCANMEARRSTLGVAVLGNCIYAVGGFDGSTGLNTAEKFDPRTQEWSTISAMSTRRSSVGVGVLHNLLYAVGGYDGASRQCLSSVECYNPETNTWTSVADMSSRRSGAGVGVLDGILYAVGGHDGPLVRKSVEAYNSETGTWTSVNDMALCRRNAGVVAMNNLLYVVGGDDGSSNLASVEVYNPKTESWTMLPSCMSIGRSYAGVAIIDKPI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00278275; iTF_01123820; iTF_00956388; iTF_00308105; iTF_00759345; iTF_00630657; iTF_00894913; iTF_01040994; iTF_01275490; iTF_01510850; iTF_00873156; iTF_01039364; iTF_01289060; iTF_00470053; iTF_01225926; iTF_01567046; iTF_00767303; iTF_00209896; iTF_01104840; iTF_00029421; iTF_00370285; iTF_00768879; iTF_00678545; iTF_01565681; iTF_01530357; iTF_01445750; iTF_01348120; iTF_01040218; iTF_00396380; iTF_01229820; iTF_01348959; iTF_00344313; iTF_01046361; iTF_01009627; iTF_00394642; iTF_00349345; iTF_00647301; iTF_00423974; iTF_00130631; iTF_01024173; iTF_00020591; iTF_00764853; iTF_00416859; iTF_00965275; iTF_00998909; iTF_01185234; iTF_01186312; iTF_01400484; iTF_01058498; iTF_01126530; iTF_00920741; iTF_01196843; iTF_01059182; iTF_01371387; iTF_01096734; iTF_00369631; iTF_00083976; iTF_00629862; iTF_00631559; iTF_00022252; iTF_00904180; iTF_00620634; iTF_00048700; iTF_00632188; iTF_00049344; iTF_00978483; iTF_01293890; iTF_01252931; iTF_00268644; iTF_00429957; iTF_01291813; iTF_00269990; iTF_01343174; iTF_01344106; iTF_00641645; iTF_00951021; iTF_01295284; iTF_00030302; iTF_00903391; iTF_00949983; iTF_00031200; iTF_00272864; iTF_01188370; iTF_01240945; iTF_00196416; iTF_00376408; iTF_01307334; iTF_01351872; iTF_00848383; iTF_00032128; iTF_01050451; iTF_00004743; iTF_00639636; iTF_00422743; iTF_00415205; iTF_00753072; iTF_00626295; iTF_00153592; iTF_01284835; iTF_00399628; iTF_00789438; iTF_01536683; iTF_01349744; iTF_01345780; iTF_00838698; iTF_01278264; iTF_01097627; iTF_01098579; iTF_00981245; iTF_00627338; iTF_00137067; iTF_00332510; iTF_01060785; iTF_01498974; iTF_00434239; iTF_00466486; iTF_00465050; iTF_01258173; iTF_00740926;
90% Identity
iTF_01498974;
80% Identity
-