Oinc030201.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Orthosia incerta
Gene Symbol
fd96Ca
Assembly
GCA_948252205.1
Location
OX411744.1:24339129-24339911[-]

Transcription Factor Domain

TF Family
Fork_head
Domain
Fork_head domain
PFAM
PF00250
TF Group
Helix-turn-helix
Description
The fork head domain is a conserved DNA-binding domain (also known as a winged helix) of about 100 amino-acid residues. Drosophila melanogaster fork head protein is a transcription factor that promotes terminal rather than segmental development, contains neither homeodomains nor zinc-fingers characteristic of other transcription factors [1]. Instead, it contains a distinct type of DNA-binding region, containing around 100 amino acids, which has since been identified in a number of transcription factors (including D. melanogaster FD1-5, mammalian HNF-3, human HTLF, Saccharomyces cerevisiae HCM1, etc.). This is referred to as the fork head domain but is also known as a 'winged helix' [1, 2, 3]. The fork head domain binds B-DNA as a monomer [2], but shows no similarity to previously identified DNA-binding motifs. Although the domain is found in several different transcription factors, a common function is their involvement in early developmental decisions of cell fates during embryogenesis [3].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 2.2e-39 4.5e-36 124.1 0.0 1 88 12 98 12 98 0.97

Sequence Information

Coding Sequence
ATGCCTCGGCCGACACGTGAGTCCTACGGTGATCAAAAACCACCCTTTTCCTACATAGCCCTGACGGCGATGGCGATCTGGAGCTCCCCGGAGCGCATGCTGCCGCTGTCGGAGATCTACCGGTTCATCACGGACCGCTTCCCGTACTATCGGCGAAACACGCAGCGCTGGCAGAACTCGCTGCGGCACAACCTCTCCTTCAACGACTGCTTCGTGAAGGTGCCGCGCCGCCCGGACCGGCCCGGCAAGGGCGCCTACTGGACGCTGCACCCGCAGGCCTTCGACATGTTCGAGAACGGCTCGCTGCTCCGCAGACGCAAGAGGTTCAAGCTGCACAAGGGAGAGAAAGATAGTTTGAATGCAGAATTAGCGGCGTTGGCCAGTTTTAATAGAGCGTTCCTGGCGCGACAGGCGGGTGCTCCTCCACCCCCGGCGACGATGCCCAATTCTAGCATGTACAGCCCGGTGTCGACGTTCATTTCGAGGCCGAGTCCCGAGCCGACAGAAGCAGTGGACACGACAGCGCTGCTGCCGCTGGGTCCGCGGCCGAGGCGTGCCTTCACGATCGACGCGCTGCTGGAGCCGGAGCCGCGACGCTCGCCGTCACCACCCGCGCAGCCACCGCCGCTGCCGCACTGCCCGCTGCCGCTGCCTCCGCCCTACCTGCTGGCTGCGCAGAGGTACCACGCTGAGCTGCTGGCCGGCCTGCAACAGTCCTGCTTGCCCCCCTTATGGACGTGGCGAGATACAAGTCAATTCTCACATTATACGCTTAATTCATGA
Protein Sequence
MPRPTRESYGDQKPPFSYIALTAMAIWSSPERMLPLSEIYRFITDRFPYYRRNTQRWQNSLRHNLSFNDCFVKVPRRPDRPGKGAYWTLHPQAFDMFENGSLLRRRKRFKLHKGEKDSLNAELAALASFNRAFLARQAGAPPPPATMPNSSMYSPVSTFISRPSPEPTEAVDTTALLPLGPRPRRAFTIDALLEPEPRRSPSPPAQPPPLPHCPLPLPPPYLLAAQRYHAELLAGLQQSCLPPLWTWRDTSQFSHYTLNS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01118068; iTF_00111413; iTF_01116983; iTF_00683138; iTF_00681476; iTF_00682181; iTF_01334569; iTF_00000995; iTF_00000129; iTF_01453092; iTF_01452151; iTF_01360421; iTF_00835361; iTF_00837281; iTF_00706756; iTF_01166406; iTF_00637288; iTF_00834440; iTF_00822699; iTF_01501899; iTF_00836333; iTF_00441296; iTF_00908624; iTF_00636083; iTF_00157013; iTF_00404505; iTF_00823737; iTF_01197534; iTF_01435872; iTF_00185123; iTF_01332357; iTF_01487525; iTF_01076198; iTF_01491691; iTF_00889004; iTF_01092878; iTF_00049712; iTF_00280944; iTF_00794133; iTF_00869435; iTF_00326898; iTF_01221307; iTF_00185952; iTF_00282080; iTF_00850406; iTF_01030945; iTF_01029029; iTF_00771687; iTF_01027112; iTF_00851530; iTF_01230323; iTF_00951606; iTF_00299962; iTF_00888028; iTF_00973533; iTF_01025791; iTF_00017991; iTF_01028074; iTF_01075185; iTF_01259889; iTF_01029970; iTF_01192434; iTF_00300981; iTF_00301912; iTF_00931034; iTF_00406523; iTF_00407377; iTF_00072060; iTF_01151873; iTF_00449934; iTF_01342032; iTF_00761438; iTF_00708988; iTF_00932229; iTF_01443644; iTF_01173085; iTF_00035454; iTF_00447979; iTF_00284340; iTF_00034518; iTF_00382382; iTF_00021152; iTF_00745439; iTF_01062566; iTF_00445921; iTF_00425186; iTF_00905925; iTF_00147112; iTF_01532840; iTF_01063561; iTF_00711626; iTF_00042443; iTF_00907691; iTF_00120300; iTF_00374988; iTF_00038509; iTF_01526829; iTF_00809871; iTF_01534607; iTF_00273424; iTF_01525744; iTF_00124049; iTF_00446929; iTF_00726097; iTF_01533745; iTF_00036435; iTF_00924403; iTF_00037588; iTF_00274260; iTF_00808916; iTF_00039605; iTF_01084949; iTF_01084950; iTF_00041591; iTF_00906871; iTF_00928471; iTF_01094711; iTF_00122168; iTF_00176920; iTF_00121209; iTF_00444921; iTF_00123162; iTF_00373722; iTF_01093850; iTF_00685243; iTF_01339771; iTF_01439707; iTF_01338300; iTF_01061693; iTF_00040606; iTF_00237278; iTF_01084062; iTF_00043295; iTF_00172543; iTF_00363839; iTF_00622623; iTF_01440799; iTF_00448832; iTF_00757952; iTF_01531776; iTF_00667168;
90% Identity
iTF_01264211;
80% Identity
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