Ogot051711.1
Basic Information
- Insect
- Orthosia gothica
- Gene Symbol
- hmgxb4
- Assembly
- GCA_949775005.1
- Location
- OX459055.1:9666585-9680480[-]
Transcription Factor Domain
- TF Family
- HMG
- Domain
- HMG_box domain
- PFAM
- PF00505
- TF Group
- Other Alpha-Helix Group
- Description
- High mobility group (HMG) box domains are involved in binding DNA, and may be involved in protein-protein interactions as well. The structure of the HMG-box domain consists of three helices in an irregular array. HMG-box domains are found in one or more copies in HMG-box proteins, which form a large, diverse family involved in the regulation of DNA-dependent processes such as transcription, replication, and strand repair, all of which require the bending and unwinding of chromatin. Many of these proteins are regulators of gene expression. HMG-box proteins are found in a variety of eukaryotic organisms, and can be broadly divided into two groups, based on sequence-dependent and sequence-independent DNA recognition; the former usually contain one HMG-box motif, while the latter can contain multiple HMG-box motifs. HMG-box domains can be found in single or multiple copies in the following protein classes: HMG1 and HMG2 non-histone components of chromatin; SRY (sex determining region Y protein) involved in differential gonadogenesis; the SOX family of transcription factors [1]; sequence-specific LEF1 (lymphoid enhancer binding factor 1) and TCF-1 (T-cell factor 1) involved in regulation of organogenesis and thymocyte differentiation [2]; structure-specific recognition protein SSRP involved in transcription and replication; MTF1 mitochondrial transcription factor; nucleolar transcription factors UBF 1/2 (upstream binding factor) involved in transcription by RNA polymerase I; Abf2 yeast ARS-binding factor [3]; yeast transcription factors lxr1, Rox1, Nhp6b and Spp41; mating type proteins (MAT) involved in the sexual reproduction of fungi [4]; and the YABBY plant-specific transcription factors.
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 1 1.1e-13 2.7e-10 42.6 3.0 5 56 144 195 141 205 0.92
Sequence Information
- Coding Sequence
- ATGCAAGAAGATTTGGAAGTCACTGGCATTTCTCGTAGTGGACGTGTGAGGAAGAAAAGTTCTAAATTGATGGACTTTGAGTCCCCTGATGATATTGAGACTAGGTTCCGCCGTCAGACTCCAGTGAAAACCTATGCCGGGTTCAGGCAGGAAGAAACTCCGGAATTCCAACCCCAAGAAAGTGCTCCACCACGGCAGGTTGAGGAAGCAGGAACAGCATCGGGCAGCGAATCCGATTACTATGATAATCCTGGCGAAAATGCTGACAGCATGGAGTCTGACAGTTCAGCATCAGACGAGGGCTCCACGCGGACCCCTGCTAACTCCTTGTATATGATGGAGAAGAGCAGCAAGAAGAAGCTGATTGTTAAGGACGGGAGGGTCATTGGGAGGGCTAAGGCGCAGAGGAAGGACAAAGGTAAAACCCGCATCACGGCGTACATGATGTGGGCAAAAGAGGCGCGCAATGAGCTCCTGCGCAAACATCCTGACATGGACTTCTCTGCTATATCGAAACGACTGGGCGAGATGTGGTCTAATgtaaaCTACAATGAGCGTTACCTATGGAAGCGTAAGGCGAAGCGCTTTGCAATGCAGAAGGAGCAAAGCACACCATCTACCAACAAGATCATCATTTCTAATCCAACTCGTCCACTAACGTCAGTCGGGCCGGGCCGCCCTCCCCGCGCCCCCCCCAAGCCTCAACAACCCGCGCCGCCTACACCCCCTACGCAAGCATTAGTGCCAGTGTCAAGCACGGCAGCGACCAGCGCAGGTATGTACCGAGTGACAGGATGTGGTGCAGTAGAAGTGGCCGCGCATCTCCGTCTGTTGGGAGAGAGCCTCGCCATCATAGGAGAACGACTCAAGGAGCATGAGGGCCAGATCGCAGTGTCGGGCTCCGTGTCGGTGCTGCTGGACACGCTGCTGTGCTCGCTGGCGCCGCTGCTGAGCGTGTGCCGCGCGCTGCCCGCCATCGCGCCGCCCGCGCGCACGCTGCAGGACACGCTGCACAACATCGCCTACATCATGCCCGGCCTGTAG
- Protein Sequence
- MQEDLEVTGISRSGRVRKKSSKLMDFESPDDIETRFRRQTPVKTYAGFRQEETPEFQPQESAPPRQVEEAGTASGSESDYYDNPGENADSMESDSSASDEGSTRTPANSLYMMEKSSKKKLIVKDGRVIGRAKAQRKDKGKTRITAYMMWAKEARNELLRKHPDMDFSAISKRLGEMWSNVNYNERYLWKRKAKRFAMQKEQSTPSTNKIIISNPTRPLTSVGPGRPPRAPPKPQQPAPPTPPTQALVPVSSTAATSAGMYRVTGCGAVEVAAHLRLLGESLAIIGERLKEHEGQIAVSGSVSVLLDTLLCSLAPLLSVCRALPAIAPPARTLQDTLHNIAYIMPGL
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01119338; iTF_00869634; iTF_01152162; iTF_00358563; iTF_00357505; iTF_00186180; iTF_00185314; iTF_01221577; iTF_00327084; iTF_01487704; iTF_00446149; iTF_01083333; iTF_01377477; iTF_00273607; iTF_00001178; iTF_00172961; iTF_00122402; iTF_01439941; iTF_00121447; iTF_00745704; iTF_01094921; iTF_01441097; iTF_00237582; iTF_00907887; iTF_01093103; iTF_00000339; iTF_00622835; iTF_00124276; iTF_01094044; iTF_00831230; iTF_01332712; iTF_01491941; iTF_00794610; iTF_01363112; iTF_00063594; iTF_01010362; iTF_00383658; iTF_00018169; iTF_00736619; iTF_01264620; iTF_01425068; iTF_00040822; iTF_00008013; iTF_01118317; iTF_01342221; iTF_00049907; iTF_00973787; iTF_00043503; iTF_00039817; iTF_00468176; iTF_00761682; iTF_01415845; iTF_00908850; iTF_01192722; iTF_00124275; iTF_00786004; iTF_00783486; iTF_00785209; iTF_00858548; iTF_00429013; iTF_00428127; iTF_00723957; iTF_01193590; iTF_00290711; iTF_00787656; iTF_00709239; iTF_00932557; iTF_01358871; iTF_00859471; iTF_00441496; iTF_01360619; iTF_00647992; iTF_01090776; iTF_00823899; iTF_01526025; iTF_00907052; iTF_00374125; iTF_00906158; iTF_00449110; iTF_00038778; iTF_00037820; iTF_00726365; iTF_00364032; iTF_01340118; iTF_01361627; iTF_01437051; iTF_00301180; iTF_00710204; iTF_00968028; iTF_01436092; iTF_00017341; iTF_01157789; iTF_01156453; iTF_01251741; iTF_00007090; iTF_01533054; iTF_00819168; iTF_00820089; iTF_01197728;
- 90% Identity
- iTF_00364032;
- 80% Identity
- iTF_01119338;