Basic Information

Gene Symbol
-
Assembly
GCA_963978525.1
Location
OZ021694.1:12868812-12872810[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 19 4.4 3.3e+02 2.2 2.8 2 20 286 304 285 306 0.93
2 19 1.8 1.3e+02 3.4 0.4 1 23 315 340 315 340 0.92
3 19 0.026 2 9.2 1.5 2 19 352 369 352 371 0.93
4 19 8 5.9e+02 1.4 2.4 3 23 385 405 384 405 0.88
5 19 0.0086 0.64 10.7 0.4 2 23 413 435 412 435 0.94
6 19 0.00023 0.017 15.6 1.9 3 23 443 463 441 463 0.96
7 19 0.064 4.7 8.0 9.5 1 23 469 492 469 492 0.96
8 19 0.016 1.2 9.9 2.3 1 20 499 518 499 521 0.95
9 19 0.074 5.5 7.7 0.0 1 20 530 549 530 551 0.94
10 19 0.002 0.15 12.7 1.7 1 22 569 590 569 593 0.90
11 19 0.059 4.4 8.0 5.0 1 23 598 620 598 620 0.99
12 19 1.6 1.2e+02 3.6 0.2 1 23 636 661 636 661 0.96
13 19 0.0071 0.53 11.0 1.2 1 23 674 697 674 697 0.95
14 19 0.0068 0.51 11.0 0.9 2 23 703 725 702 725 0.93
15 19 0.0029 0.22 12.2 0.8 2 23 729 751 728 751 0.96
16 19 0.0014 0.1 13.2 4.9 1 23 757 780 757 780 0.96
17 19 0.065 4.8 7.9 1.6 1 23 785 807 785 807 0.98
18 19 6.3e-06 0.00046 20.6 4.8 1 23 813 836 813 836 0.98
19 19 0.0019 0.14 12.8 0.1 5 23 850 869 842 869 0.87

Sequence Information

Coding Sequence
ATGGCAACTAAAGATACTTGTTTGTATTGCAATTTTACTGCAAACGGCGCTACTGCGGAGGATAGAGAATTCCATAAtgtttttgatgaaattgGCATAGATTTACAATTACCCATTTTGGTGGAAAAGTATTTCCACATAAGTGTACAAAAACCGAAACATCAAAAAATGTGTGATCAATGTTTAAATCATCTTATCGAACTGTTTGATTTAGATGAACATGGAAAAAGCCAAAATGCAGaattaacaaaatcaaaactGGCAGAAACCCAAACATTGCAGGAAGgacaaaaaattgataaacCTATCAATATGTCCACAGaaatagataaatatatacttaacaATGAAATTGAACCGGGAACTGTTATAACTAAAGAAATAGACCATCAAGAGGGATTTAATAATGAAGTTGAAACAGGAGGGGTTataattagtaaaattttaccaTTAGTTGATGATggtaatgataataatagaGGAAAtctaattgtaattaaaaaatttaagtcgaGTATAGATGAGATTGATAATACAGTAGAGCATAATGAAGCCAGTGATAGTCAATCGTTTGatgatgaaaattttgtaatagaaGAGCTCGAAGAAAATTCCGATGATTTTGAACTTATTTCCAATTCCGAGGATAACGACCAATCGCAAAATGAAGAAGAACTATGTTTTGAAATAATTGATGAAAATGAGCTTTTAACCACAACTCAAACTAAATTTACTACAAATAATCTTATTATGGAAGgTTATTGCTCTCAGGATTATGATTTAGTAGATATTAATTCTTATCTAGATTCAGTTTTAACGACAAAATTTGAAACTTTAGATCTACAATGGACCAACAAATGCATGCTTTGTAGCTGTATGTATAACACACTAAATGAATTGCTCAAGCATTCTTGCGTAACTAAACAAATTGATGAAAATAACTTCAAATGCCTGCTAAAAGACTGCAATGTAGAATGTATTAATATAGAGTCGCTAGGAAGACATTTGGTAATAAGACATTATAAAGCTTTAGACAGTTTACATGTGTATGGAAGTTGCCCTGAATGTCAATGGACATTTTCCAATTTCCCTCTTTACAATAAACATTCATGTTGTCGTCATTTAAAACGCAAAGCGGGtgtaatgaatttttgtaaatattgtaaattggaGTTTCCTTCATTGAAACgatatttttttcatatgcaatttcatttaaacaaatatcGACCAAAAGTGTGTTTGATTTGTGAAATGTCTTTTAATAATAGCAATGACTTCTTCGAGCATGTTCAATACAGTCATGAACCAGAAAATGCTTTGGCCTGCAAAAAATGTGATCGTTTCTTTAAGGATAAAAACTTGTATGAATCTCATGTGAAGAAGCATAATTCCAATGGTGGTTATCACTGTGCACATTGCAATCAAAGATATGAACATCGTCACAATTTAATACATCACTTGGAAGTGTATCACAATCGTAGAGCAAAACGATTTCGTTgcgaattttgtaaaaaagtgtttatgggtagaaaaaattatcttaaacATTTACCATTTCATTCTCAGGAAACGGAAGTTCACAGTTATATATGTTCTCAATGTGGTCTAGTTAGCGGTAATATTGAAGATTTAAATAATCATATAGATTCTACCGCTACATGCTCGGAAGCCTCTATTAAGGAACAGATCTTGTcagttgtttatttttgtgaaaattgtgGCATTGAGTTTGATACAGTTGAACATTTATGTAAACATCGTTTATCACCCGAACATAATGATCTATTGTTTAGATGTGTgttgtgtgaaaaattttttaatgaatttcgttGTGTACGGAGTCATATGAAAactcataaaaattatttaagttgGTTAGAAACTTTTCCGGTGTGTAGACTGTATGTCTGCAATATGGGAGAATGTCGAGACACTTATCCGGTATGGACTTCTTTATATTATCACAAAAAACGGCCCCACGTTAAGGGTGCGAAAAATAAAGACAATGTCAATGAATTTGTCTGTCAATTTTGTAAGAAAGAATGTCCTACAAAAATGTCATTAGCTGTTCATGTGGCCCGTAGTCATAATACTAaaaacaTTAAATGTTCACATTGCAATAATTCGTATAAAGATGAGAAAGCCTTACAAGGTCACATTGATTATATGCATGTACCGATCAAATGTGATCAATGCtttaaagtaataaagaatcgtcgaaattttgaaactcATGAACGTGTCGTGCACAAACGAACGCAACGTTACTTCTGCAGTCACTGCTCCAAGGGTTTCTATCATAAAAGTGAAATGGAAAATcatgtgaaaaatattcacaCCGATGTCGTCTACACCTGCTCACAATGTTTTTTTACCactaattatgaaaattctttaaagATTCATGTGGCCAAACATAATAATGAACTGGCATATCAGTGTAAATCTTGTCCGAAATCATTTACACGCAAACATGTACTACAAATGCATATGCGTAGACGACATCGGAGCAAAGAGCTAATTTGTAATGACTACATTGAATCGGGTTGTGAAGAAGCTTTTGTTACACGTCGTGATCTAAAGAGGCATATAGAGAGAGAACATCGTCATATTCCGGTTAGAGAGTTGAAGGGAAAAAATATTCgcaaaaaatctaaaaatttaaaaacaggTGTTGCTTTAATTGAAGAGAATGTAAATGAACAACAGGAGGAGTGTATGCTGATAGAAGAAATGTCTAATGAATCTCTAGATTATGATATCAATGATGAGGCTGATGGCAAAAATGTAGGTATAACCATAGAATATCTAGATGATCATGAGgaatacaaataa
Protein Sequence
MATKDTCLYCNFTANGATAEDREFHNVFDEIGIDLQLPILVEKYFHISVQKPKHQKMCDQCLNHLIELFDLDEHGKSQNAELTKSKLAETQTLQEGQKIDKPINMSTEIDKYILNNEIEPGTVITKEIDHQEGFNNEVETGGVIISKILPLVDDGNDNNRGNLIVIKKFKSSIDEIDNTVEHNEASDSQSFDDENFVIEELEENSDDFELISNSEDNDQSQNEEELCFEIIDENELLTTTQTKFTTNNLIMEGYCSQDYDLVDINSYLDSVLTTKFETLDLQWTNKCMLCSCMYNTLNELLKHSCVTKQIDENNFKCLLKDCNVECINIESLGRHLVIRHYKALDSLHVYGSCPECQWTFSNFPLYNKHSCCRHLKRKAGVMNFCKYCKLEFPSLKRYFFHMQFHLNKYRPKVCLICEMSFNNSNDFFEHVQYSHEPENALACKKCDRFFKDKNLYESHVKKHNSNGGYHCAHCNQRYEHRHNLIHHLEVYHNRRAKRFRCEFCKKVFMGRKNYLKHLPFHSQETEVHSYICSQCGLVSGNIEDLNNHIDSTATCSEASIKEQILSVVYFCENCGIEFDTVEHLCKHRLSPEHNDLLFRCVLCEKFFNEFRCVRSHMKTHKNYLSWLETFPVCRLYVCNMGECRDTYPVWTSLYYHKKRPHVKGAKNKDNVNEFVCQFCKKECPTKMSLAVHVARSHNTKNIKCSHCNNSYKDEKALQGHIDYMHVPIKCDQCFKVIKNRRNFETHERVVHKRTQRYFCSHCSKGFYHKSEMENHVKNIHTDVVYTCSQCFFTTNYENSLKIHVAKHNNELAYQCKSCPKSFTRKHVLQMHMRRRHRSKELICNDYIESGCEEAFVTRRDLKRHIEREHRHIPVRELKGKNIRKKSKNLKTGVALIEENVNEQQEECMLIEEMSNESLDYDINDEADGKNVGITIEYLDDHEEYK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01114497; iTF_00384786;
90% Identity
iTF_00384786; iTF_01114497;
80% Identity
-