Basic Information

Insect: Ornithomya chloropus
Gene Symbol: ush
Assembly: GCA_963971445.1
Location: OZ020530.1:49583722-49592777[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.065 5.4 8.1 0.0 6 20 241 255 237 257 0.95

2 9 0.0004 0.033 15.0 0.6 1 23 310 332 310 332 0.98

3 9 0.056 4.6 8.3 1.0 2 21 364 383 364 384 0.92

4 9 0.058 4.8 8.2 2.9 2 21 769 788 768 789 0.93

5 9 0.011 0.89 10.5 0.0 3 21 830 848 828 849 0.91

6 9 0.72 59 4.8 0.2 1 23 949 971 949 971 0.91

7 9 0.00092 0.077 13.9 0.7 1 23 977 999 977 999 0.99

8 9 0.0013 0.11 13.4 0.8 1 23 1069 1092 1069 1092 0.96

9 9 0.7 58 4.8 0.6 2 20 1215 1233 1214 1235 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.065	5.4	8.1	0.0	6	20	241	255	237	257	0.95
2	9	0.0004	0.033	15.0	0.6	1	23	310	332	310	332	0.98
3	9	0.056	4.6	8.3	1.0	2	21	364	383	364	384	0.92
4	9	0.058	4.8	8.2	2.9	2	21	769	788	768	789	0.93
5	9	0.011	0.89	10.5	0.0	3	21	830	848	828	849	0.91
6	9	0.72	59	4.8	0.2	1	23	949	971	949	971	0.91
7	9	0.00092	0.077	13.9	0.7	1	23	977	999	977	999	0.99
8	9	0.0013	0.11	13.4	0.8	1	23	1069	1092	1069	1092	0.96
9	9	0.7	58	4.8	0.6	2	20	1215	1233	1214	1235	0.92

Sequence Information

Coding Sequence: ATGCTAGATGTGACAAGTGTTCAGGGAACTACCCATGCCTCTATCCTCAACGTATCACAATTCGCCAGGGCAGATCCTAAAGATTTCAGTATCAAGAATGATGCCATAGATGTTGTTGAACGTAATTCGAATTCTACCCCACCAAGCACTAGTTTAACCTGGGATACTGATGTAGAAATGGCAGATAAAAGCGTGGATAGCATTAATGCAAAAGTTGTGGATACATTTCCTGAAAAATCAAGTGATGAAAAATCTCTTGAATATAGAGAAATTAAAGAAGAACTGAGTAGAAGTTCACACGATTCAAGTGAGCATAGAGAAAGTGGTTCTATGGAACGTAATTCATCTGTTTCACCAAAATACGATGCAGATTTAATGACTGATGAATCGAAAGAAATAACACAAAAGACTCCACCAAGTTCGGATATACGAAATTCTCCATTAAGTAGCTGTAATTTACCAAAACTAAGATTAAATGCCCTTTTGGCCTCAGATCCAGCTCTAAAGCCCGATGCCAAAGATCTCAAGCTATTACAGGAAGAAGCTCAAACTCAGCACCGCAAAGGACATTTCACCCATACCATACCCACTGAAAAACTAACCGCAATGGAGAATAATATCAATAACTTGCCCGTCGAACCGGTGATAAAATCGGGACCCTCTGCGGTGGAAGTTcctccaccaccacctccGCGTATGAAAGTTTTCATGTGCATACCATGTGGCATTGGTTTTAGTTCTCCTTCAACTTTAGAAGCTCATCAAGCTTATTACTGTTCCCACAGGCATAAAGAAGCAGAAGAGAACTCCGCACCTTCTTGTTCTACGACAGAGAAAACTATGACATCGCCTTCCCTTGTGACTAACTCCTTCACGAATGCTCAGAGTTCCGAGCCAACAGTTAAAGCTCACAAAACTGGGAAACAATACGCGTGTACGCAATGTTCATACAGTGCGGATAAAAAAGTTTCCCTTAATCGTCATATGCGCATACATCAGTCATCACCAACGCCAACGCCTAATGTGAGTACTGCGAATAATGCGGTTTGCTCCCAGCTGGATGATAATTCTAGTCAAcaaattgaTCGATATTGTAGTGATTGTGACATTCGATTTAATAATGTGAAAACCTATCGAGCTCACAAACAGCACTATTGTAATTCGCGGCGGTCGGAAGGACCATTGACTCCGAAACTTGAAGTCTCAAGCTCGTGTCATAGCAATAAAAGTGTTAATTCGGTAACCAGTGGGATAATCAGTCCTCAGAACCGTACTAAGACTCCTACACCTGGTATGATGGCAGCTGTGGCTGCTTCACCATTCCTACTTTTGCCCACCAATCCGGTTTTAATTATACCGTACTCGGTGATACGTAGCGCAAGTGTAATTGGGGGTCCCTCAGCTTTCTCTTCACCTGGTGTGATTAACCCAGATACTACGTGCTTTGCTTTGGAGAATGGTAACCTTAAACCTCTGGCCACAGTCGTCAATATTAACACAACGCTTAATAATGcaacaaatcaaaatttggccAGTAACAGCCACCAATTGGTAGACAGCACGCTTCATCAGACAACACCATCCAACAGTAATGAATCGTCGGTAAATGaaaagaatattaaatataatacagATGATTCTAGAGAGAGTACACCAAAATCTAAGGAGAGAACTTTCAGAGAGTCAACCCCACTAGACTTATCGCTGCGGCGTTCGCCCATAACTACTTTGTTGCAACGTCAACGTATACATTCCGATGGTGTGGAAAGGGAAACTGTCCCCGATATGGGAAGGGACCACATTGCACATGATGAGAGTGGTTGCGTAACACCGGAACAAATTGTGTGCGCTCCCTCATTACCTAATAGTCCTACAATGACACCATCTCCTTGCCGAAAAACTACAAGTCCAAGAAGTTCGGGTGCATGCAGTAACTCATCCATATCACCACCATCTACAACTGCCATGTCCATCAATCTGATAAGTAATTCTACCCATCTATTGGAGAATTTACAATTCAGATCCATGATGCCGACTGATATATTGAATCCAATATTGGCTAAGCAAAATTTAGAATTGGCATTAAAGTTATCCgttgcagcagcagcagttaGTTCTTCATCCGGTGCAATGCAATCTCACAGTTCTAATCCAGCCGAATTAGCAGCAGCTGCTGTGGCAGCGGCTACCGGTCGAGCCCAATTGCTGGGTTTGCCTGTTTTGCCACCGGTAGGTAATGCTTCGGGAGGCAATTCTATTGCTACTGGCAATCAACcgcaaatatttgttaaacaGGGCGTTTCCAAATGCAAGGAATGCAATATTGTGTTTTGTAAGTATGAGAATTATTTAGCTCACAAACAGCATTACTGTTCGTCGCGTAATCAAGACGTTGGAGATGCAGAGTCTAAATCATCTCCAACACTAGCTTTGGCGAACTCTGCGCCCGCTACTGAAAATACGCCAGTAGCGTATCAGCAATTGATATGTGCCGCCTGTGGCATTAAATACACTTCATTGGACAATTTGAGAGCTCATCAAAATTACTATTGTCCGAAGGGTGTGGGGGCAGCGGCTAGTGCCTCTGCCCCAGGAGCAACTGGTCAAATGCCTTTAACCAAAGAAACCAAATGCACCAAATGCAATACCGTGCACGAATTAACTTTGTCCTGTCCAATGTCTCCAGTTttacagcaacagcaacaacaacaacagcagcagcaacaacaacaacaacagcaacaacaacaaaaacaacaacaacaacaacaacaacatactgctttatttttatcatCGTGTGGCAATATCTCAACGGGCAGTGGAAGCAACACCCAAAACCTATACAAATGTCCATTGTGCGATGTAATGAGCTTGACGGCCACCGAAAGTCGCAAACACATGGAAACCCACGGTACCGTTAAGGCGTTTCGTTGCACTATATGCGGTTATAAGGGCAACACCTTGagGGGTATgcgcacacacatacgcatgcATGTTGATAAAAAGACGAATGATTTTAATGAAGAGCATTATATGACGTGTATACTTGAAGATGAAAACATTGAAATTCCTACAGTTGATCAATtagcaaaacaacaacaacagcaacaacaacatcaaaaacaTTTACATCAAACGTCTGCCGTAAGTGCTGCTGTGCCGACAGCAgattttcaacaacaacaacaatcacaacaGGTGTTTAATTGTGATATTTGCAGCTATACATCCACCTATAAAGGCAACGTGTTGCGCCACATGAAACTGCTACATCCGCATGCCCTAACCAATTCACCGTCTATTTCTCCCGAGGTAGCCGCTCCAGATACAAATGACAGCCCCTCACTGGCCAATAGTCTTAATGGTGATAATTCGCTTCACAGTTTTACTATCAAAACTGAACCAGTAGATAATACGGCACCCAACCCGGCCATATCTGGTGTTATACTTAATGCGCGCGACAATAATAATTCTTTTATATCTAGTACGGCTCATCTGGCAACAAACAACGACATGGCAACGATGATGACAAATATTAAAACCGAGCCCATGGAGTTGGCAGTAGAATCATCGACACCGGTACGGGGACCACCGCCATCTACCTTAAATAATACTCTGGACGAGTgcattaatcaaaaatattgtcAGAGCTGTGACATATCATTTAACTATTTGAAAACATATTTAGCTCACAAGCAATTCTATTGCAAGAATAAAATCAAACGGTCGGACGGTAGTGATAGTCCCAGTCCAAATCCAGATAACTTGATCATGTCCATGCCGTCACCCAATAATTTgccaattcaaaaaaataaGGAAAATATGCAACAGGAGGCGGCCATATGA
Protein Sequence: MLDVTSVQGTTHASILNVSQFARADPKDFSIKNDAIDVVERNSNSTPPSTSLTWDTDVEMADKSVDSINAKVVDTFPEKSSDEKSLEYREIKEELSRSSHDSSEHRESGSMERNSSVSPKYDADLMTDESKEITQKTPPSSDIRNSPLSSCNLPKLRLNALLASDPALKPDAKDLKLLQEEAQTQHRKGHFTHTIPTEKLTAMENNINNLPVEPVIKSGPSAVEVPPPPPPRMKVFMCIPCGIGFSSPSTLEAHQAYYCSHRHKEAEENSAPSCSTTEKTMTSPSLVTNSFTNAQSSEPTVKAHKTGKQYACTQCSYSADKKVSLNRHMRIHQSSPTPTPNVSTANNAVCSQLDDNSSQQIDRYCSDCDIRFNNVKTYRAHKQHYCNSRRSEGPLTPKLEVSSSCHSNKSVNSVTSGIISPQNRTKTPTPGMMAAVAASPFLLLPTNPVLIIPYSVIRSASVIGGPSAFSSPGVINPDTTCFALENGNLKPLATVVNINTTLNNATNQNLASNSHQLVDSTLHQTTPSNSNESSVNEKNIKYNTDDSRESTPKSKERTFRESTPLDLSLRRSPITTLLQRQRIHSDGVERETVPDMGRDHIAHDESGCVTPEQIVCAPSLPNSPTMTPSPCRKTTSPRSSGACSNSSISPPSTTAMSINLISNSTHLLENLQFRSMMPTDILNPILAKQNLELALKLSVAAAAVSSSSGAMQSHSSNPAELAAAAVAAATGRAQLLGLPVLPPVGNASGGNSIATGNQPQIFVKQGVSKCKECNIVFCKYENYLAHKQHYCSSRNQDVGDAESKSSPTLALANSAPATENTPVAYQQLICAACGIKYTSLDNLRAHQNYYCPKGVGAAASASAPGATGQMPLTKETKCTKCNTVHELTLSCPMSPVLQQQQQQQQQQQQQQQQQQQQKQQQQQQQHTALFLSSCGNISTGSGSNTQNLYKCPLCDVMSLTATESRKHMETHGTVKAFRCTICGYKGNTLRGMRTHIRMHVDKKTNDFNEEHYMTCILEDENIEIPTVDQLAKQQQQQQQHQKHLHQTSAVSAAVPTADFQQQQQSQQVFNCDICSYTSTYKGNVLRHMKLLHPHALTNSPSISPEVAAPDTNDSPSLANSLNGDNSLHSFTIKTEPVDNTAPNPAISGVILNARDNNNSFISSTAHLATNNDMATMMTNIKTEPMELAVESSTPVRGPPPSTLNNTLDECINQKYCQSCDISFNYLKTYLAHKQFYCKNKIKRSDGSDSPSPNPDNLIMSMPSPNNLPIQKNKENMQQEAAI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01115307;
90% Identity: iTF_01115307; iTF_00384889;
80% Identity: -