Basic Information

Gene Symbol
-
Assembly
GCA_035582935.1
Location
JAWWEM010000027.1:18896113-18899929[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 20 0.018 2.4 9.7 0.1 1 23 30 52 30 52 0.98
2 20 0.11 14 7.3 0.0 3 23 59 80 57 80 0.94
3 20 6.4e-05 0.0085 17.4 6.7 1 23 85 107 85 107 0.98
4 20 0.0044 0.59 11.6 0.1 1 23 126 149 126 149 0.94
5 20 0.11 15 7.2 9.4 1 23 158 180 158 180 0.99
6 20 0.016 2.2 9.8 0.1 2 23 187 207 186 207 0.96
7 20 4.1e-05 0.0055 18.0 1.0 1 23 213 235 213 235 0.98
8 20 0.036 4.8 8.8 2.0 1 16 241 256 241 257 0.91
9 20 0.0031 0.42 12.1 0.8 1 23 313 335 313 336 0.96
10 20 5.4e-05 0.0072 17.6 4.3 1 23 342 364 342 364 0.98
11 20 9.5e-05 0.013 16.9 8.1 1 23 391 413 391 413 0.95
12 20 0.00043 0.057 14.8 4.7 2 23 419 440 418 440 0.96
13 20 0.0094 1.3 10.6 0.3 1 23 445 467 445 467 0.97
14 20 1.1e-06 0.00015 22.9 1.4 1 23 475 497 475 497 0.98
15 20 0.53 71 5.1 4.2 1 23 503 526 503 526 0.94
16 20 0.00021 0.028 15.8 0.3 3 23 539 559 537 559 0.96
17 20 6e-06 0.0008 20.6 2.0 1 23 565 587 565 587 0.96
18 20 3.1e-08 4.1e-06 27.8 0.2 1 23 593 615 593 615 0.98
19 20 2.3e-07 3.1e-05 25.1 0.9 1 23 621 643 621 643 0.98
20 20 0.00054 0.072 14.5 1.7 1 21 649 669 649 670 0.96

Sequence Information

Coding Sequence
ATGTATTGTTACGTTCGAAACAACGCCGACATAAAAATCCCTTGTGTACATTTCAGATACAAGCGCAAGTCCAAGAAGTCAAAAATCTTCGAGTGCACTTACTGTTCGATGATCTTGCCAAGCGACCCTCAACTAGCTCTGCACGTCCGCACGCACACGAACAAAAGCTATGGGTGTACCTTTTGCGGCATTCCTCTAGTCTCCAGTGAAGCTCTCAGTCAGCATCTCGGCAAGTACCACAAAGATGCGTGCTTCACTTGCCCAACCTGTTGGAAGTGTTTCTCGACCAAGCACGGCTTCACGCTTCACACGCGCTCTCATTACGGAAAGAACGTTAAGGAACCTGCTGCGAGTAAGAAACAGCCAAAGAAGAGATTCGCTTGCCCAGTGTGCAACGCGAAATACACGTCGTACGCGTACCTGTCTGTGCACGCAAAGCTGCAGCACGGCGACAAAAGTACTCGGGAGACCTACAAGTGCCATCAGTGCGAATTTACCAGCAACTACAAAACGAGTTTACACAAGCACTTCAAAACGCACACGGGCGAGAATCTAGTCACTTGCGAAGTGTGCGGAAAGAGAGTGGACAAGTTTTATTTAGCGATACACTCGAGGATTCACACTGGCGAAAAGCCCCACGTCTGCAAAGTATGTAACAAAGCTTTTGGCGTGAAGAAGTACTTGATAGTACACGAAAGGACGCACACTGGCGAGAGGCCATTTCAGTGCACTTTCTGTGACAAAAGATTCGCCTACCCCGAGCATTATTACCCTATGACGGTCTTGGCAGGGGAAAATAACTACAAGCGGCCCTCTTCGCCCGCCGTAATCacgaagaagaagcagcaaaTGAAAAAGCTCGAGTCGGAGCTGGTCGTCGTCAAGGTTGAGGAGGACCACAGCGAATTGTTTCTTGACGAGGACATGCCCCTGTCCTACCGCTGTAATCTTTGCAACGTCTACTTCGCCAAGCAGCCCTTGCTGGACATGCATATTTTGATGCACCACAAGGTAAAGAACAAGTACGACTGCGCACACTGCGGCAGGAGCTGCCGCACAGCTTTGAGCCTTCGCCAGCACATGAAACGCCACAACAACGTCATCGTTACGCGTTCGACAAAGACCGAAGAGGAAATTCAGTCGGAGGAGGAGCCTCAGCAGCAGCAAAACTTTCTGTGCAAGACCTGCGGCAAGACGTTCCATCACAAAAGTAATTATCAAAAACACCTGTCCCGGCACATTGCCGGCGAGCTTAATTGCAAGCACTGCCCGAAGAAGTTCCGTCTCTTCCGCGACTTGACGCGACACGAGAAAACACACTTCCTTCCGAGCTACGCGTGTAAGGAGTGCGAGTACGAAACTACAGTCTTAGCTGCTCTACATATACATATGACCAGGCACACAGACAAAGGCGAGCTGCCCTTCAAGTGCAACGAATGCGACAAGCGATTCAGAAAAGCGACGGAGCTTCAAGAGCACTACAACATACATTCGGGCGATAAACCCTTCGTCTGCCAGACCTGTTCAGCCGCTTTCTGCCTGAGAAGGCAGCTATCGGCGCACTGCCGACGCTTACACCCTGAACTGAAGGCGCAAAAAGTAACCAGTACCGCGTGCGACATTTGCGGCAGGGTATTAGCTACAAAAAGGTCCTTATTCAGACACAAAGAGAGCCACAATCCAACGAAGCTCTACCTCTGTGATTTTTGCGGAAAGAGTCTCAGCAGTGCGGAGCACCTGAAGAAGCACAGGCGAATTCACACCGGCGAAAAGCCGTACGTCTGCGATATATGCGGAAAGGGATTTACGGATTCCGAAAATCTCAGAATGCACAGGCGAGTGCACACCGGAGAAAAGCCCTATAAGTGCGATCAATGCCCGAAGGCGTTCAGTCAGCGATCGACCCTCACCATTCATAGGAGAGCTCACACCGGGGAGCGGCCATATGTATGCCAGATTTGCCACAGGGGATTTTCGTGCCAGGGCAACTTGACTGCCCATCAAAAATCTACTTGTGTGTAG
Protein Sequence
MYCYVRNNADIKIPCVHFRYKRKSKKSKIFECTYCSMILPSDPQLALHVRTHTNKSYGCTFCGIPLVSSEALSQHLGKYHKDACFTCPTCWKCFSTKHGFTLHTRSHYGKNVKEPAASKKQPKKRFACPVCNAKYTSYAYLSVHAKLQHGDKSTRETYKCHQCEFTSNYKTSLHKHFKTHTGENLVTCEVCGKRVDKFYLAIHSRIHTGEKPHVCKVCNKAFGVKKYLIVHERTHTGERPFQCTFCDKRFAYPEHYYPMTVLAGENNYKRPSSPAVITKKKQQMKKLESELVVVKVEEDHSELFLDEDMPLSYRCNLCNVYFAKQPLLDMHILMHHKVKNKYDCAHCGRSCRTALSLRQHMKRHNNVIVTRSTKTEEEIQSEEEPQQQQNFLCKTCGKTFHHKSNYQKHLSRHIAGELNCKHCPKKFRLFRDLTRHEKTHFLPSYACKECEYETTVLAALHIHMTRHTDKGELPFKCNECDKRFRKATELQEHYNIHSGDKPFVCQTCSAAFCLRRQLSAHCRRLHPELKAQKVTSTACDICGRVLATKRSLFRHKESHNPTKLYLCDFCGKSLSSAEHLKKHRRIHTGEKPYVCDICGKGFTDSENLRMHRRVHTGEKPYKCDQCPKAFSQRSTLTIHRRAHTGERPYVCQICHRGFSCQGNLTAHQKSTCV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01112855;
90% Identity
iTF_01112855;
80% Identity
-