Othy012504.1
Basic Information
- Insect
- Ormyrus thymus
- Gene Symbol
- -
- Assembly
- GCA_035582935.1
- Location
- JAWWEM010003388.1:1-4352[-]
Transcription Factor Domain
- TF Family
- MBD
- Domain
- MBD domain
- PFAM
- PF01429
- TF Group
- Unclassified Structure
- Description
- The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 2 4 2e+04 -3.8 0.0 19 38 94 114 91 117 0.68 2 2 2.5e-10 1.3e-06 28.9 0.2 15 72 523 576 520 579 0.91
Sequence Information
- Coding Sequence
- ATGTCGAATAGTAATTCTTCACAgttgataaattttccaaagcTAAATGCTGATAATTACAACAGCTGGAAATTGGATATGAAAGTGTTGCTGATTGATCGCGGATCTTGGGAGTTTGTTGATGGGACCGCAGAGGAACTTGGACAAGATGCAAAAGCTCCGGAAAAAGCAGATcataaaagaagaaaggaaagGGCTTACACGACCATTTATCAAGGCATTGAAAGGCAGTATTATCCTCTTATCGCTAACACGCTCGATGGGAAAGGTGAATTGACATTTTGTATTagggaaaataataagcaaacacaagtgaaattgaaaaatgtgttATATGCACCTAATATGAGAAGGAATTTGTTAAGCGGTGCTTGCATGGACATTGCAGGATGTTccataaaatggaaaaataacaAGATGATTGTCCACCGTAAGGACAACAGTTACTTCTTCACCGCTCATAGAAAAGAACGTTTCTATGTTATCTATGCTGAATATGAATCAGACAATGAATCTCACAACACAAGTATAAGTGACGATGACATGAAAATTCATAGAAGATTTTGTCACATAAACATGCAGAATTTGAATCAAATGGAAAGAAGAGACATTGTACGTGGCATTGAAAGAATAAATAGTTGTGATATTAAGTGTGATACTTGCCGAACAAGCAAATCCACTAGATCATCTTTCAAGGAAAAGCCGTGCATTATGTCAAAAAGCATTCTGGAGAGAATTTATATGGATGTATGGGGACCATCTCCAGTAACCAGTGCAGGTGGTGGAAACTACTTTTTGTCCATCATTGATGATTATTCAagaaagagttttatttttataatgaaaaataagtctgaagtttttgagaaattcaaaacttttatgaGTGAAGTGGAAAGACAGACTGACTCAAGAATCAAAATTGTACGCAGCGATAATGGCATGGAattttgtcataaaaaattcgaaGATTTTCTGCAGAAGAGAGGCATAAAAATTGAGAGAACCTCTACTTACACCCCCGAGCAAAATGGAGTTGCAGAAAGATTCAACCGTACTGCAATGGAAGGAGTCAGAGCGATGTTACAAGATAGCGGACTGCAAAAAAGATTTTGGGCAGAAGCATTAGCGAATTTTGTACATGTTAAGAACAGAAGTATGCACAGTTTGCTGAATGATTGTACACCTGAAGAAAAATGGTGGGGCAAGAAGCCATCCGTTCAGCACTTCAGAATTTTTGGATCTCTGGCATATGTTCATGTACCTAAGAACAAAAGAGACAAGTTGGAGCAGAATGCTGAACTTGGGATTTTGGTTGGATATGCTCTGAAGACAAAAGGATACAGAGTTTGGATGCCTAAAACAAGGAAAGTTGTTGAAACAATACATGTAAAAATTGAGGAAAGCAAAAATGGAGTAGATACTTTATTTGGAAGAGGGACTGTAAGTACAaacaattatgaaattaattatgataatactGAATTTATTGAAGGTCAAGTTGAACAAGATATTAACCAAGATGAGGATGAAAATGGCCCAGTAAATTTGACTGATATGTCACGATGGACCAGATTGGAAAAACCAAGGACAAATGAGAATAGAGTtgatgtatattattattctccAGGTGAAAATCTGAGATTGAGATCCATGAATGATATCAAGAGATATTttcaagagaaaaatttacctctaattgaagagaattttaattttaaacctaCTGAATCCATAATTCAAGAAAAGGAAGCAGCCCCAGTTGTAAATGCTGAAAATCAAATGAGAAACATTCTTGAAGAGATTGAAACTGCTGGTCGAGAAGAAGTACTCTATATTGAAGCACCaatgaattttgaagaaaGTCAAAGATCTGACAAACGAGAAGAGTGGAACAAGGCGATGAATGAAGAGTTAGAAATGATGAGATCAAGAGAAGTTTGGTCACTTGTTGACTTACCAGCAGATAGTAAG
- Protein Sequence
- MSNSNSSQLINFPKLNADNYNSWKLDMKVLLIDRGSWEFVDGTAEELGQDAKAPEKADHKRRKERAYTTIYQGIERQYYPLIANTLDGKGELTFCIRENNKQTQVKLKNVLYAPNMRRNLLSGACMDIAGCSIKWKNNKMIVHRKDNSYFFTAHRKERFYVIYAEYESDNESHNTSISDDDMKIHRRFCHINMQNLNQMERRDIVRGIERINSCDIKCDTCRTSKSTRSSFKEKPCIMSKSILERIYMDVWGPSPVTSAGGGNYFLSIIDDYSRKSFIFIMKNKSEVFEKFKTFMSEVERQTDSRIKIVRSDNGMEFCHKKFEDFLQKRGIKIERTSTYTPEQNGVAERFNRTAMEGVRAMLQDSGLQKRFWAEALANFVHVKNRSMHSLLNDCTPEEKWWGKKPSVQHFRIFGSLAYVHVPKNKRDKLEQNAELGILVGYALKTKGYRVWMPKTRKVVETIHVKIEESKNGVDTLFGRGTVSTNNYEINYDNTEFIEGQVEQDINQDEDENGPVNLTDMSRWTRLEKPRTNENRVDVYYYSPGENLRLRSMNDIKRYFQEKNLPLIEENFNFKPTESIIQEKEAAPVVNAENQMRNILEEIETAGREEVLYIEAPMNFEESQRSDKREEWNKAMNEELEMMRSREVWSLVDLPADSK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01112599;
- 90% Identity
- iTF_01112599;
- 80% Identity
- -