Olab007041.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Ormyrus labotus
Gene Symbol
ush
Assembly
GCA_035582975.1
Location
JAWWEO010000036.1:3250019-3256269[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 8 0.011 1.1 10.5 0.4 3 21 290 308 288 313 0.91
2 8 5.4e-05 0.0056 17.7 1.3 1 23 350 372 350 372 0.98
3 8 0.14 14 7.0 1.9 2 20 414 432 413 434 0.93
4 8 0.018 1.9 9.8 4.4 2 21 669 688 668 689 0.94
5 8 0.072 7.6 7.9 0.0 3 20 716 733 714 735 0.90
6 8 0.0077 0.81 10.9 0.0 2 23 774 795 773 795 0.96
7 8 0.011 1.2 10.4 1.4 1 23 801 823 801 823 0.99
8 8 0.096 10 7.5 0.4 3 21 940 958 939 959 0.92

Sequence Information

Coding Sequence
atGGTGCTGCTCGCGCGCAGGATTTCCGGTTTTAAATgGGAGGATGAGGAGTGGAGCGATTCGGAGAAGACACCGTCCGTGAGCAGCGGCCTGGAGGGTTGCGGCTCGGCAGTCTCCAGTCCCTCCGGCCAGCTGGTGGACGAGGAGCTGGTCGCCCTGCCGCCTCCGCCGCGACTCAGCGCCGCGGGACTGCCGACGCCCGACGACGTCAGGCTCAGGCTCGGCGCCCTCAACGACGATGTGCGCAAGAGGCTCGCCGACGAGATCGAGAACGTTCGAGCCCTGCGGAACCAGcaccaccaccagcagcatcatcatcatcatcaccaGCAGCGGCCCCCCTCCCGGCCGCCCTCCGTGCAGGACTCGTCGCCCAAGTCGCGCCCGGAGGCAGCCGACGAGGACTCGAACCTGGCGGTGCGCGAGGACGAGCGcagcgcctcctcctcctcgtcgagcagcggcagcctcCGCCGCGGCCAGGCCCTGCGCAGGGACTCGGAGGAGTCGTCGCGCACCAGGTGCCCCTCCGCCGGCGACGAGGTCGCCGAGCCGAAGCGGCCCCGCctggaggaggaggcggcggcggcggcgaccgtCGCCGCGCCCCGACTGAGACTCAATGCTAGTCTGGCGACGGACCCGGCGCTCCGACCCCAAGCCGTCGCCGCTCTTACTATTAAACCCGAGAACGCCGCCTCGCCGCCCAATCCCACGCCGCCCCTCGCCGCCGGTCTTCAGAACGCGATAGCAACGGGCCACCTCTTCGTGCTGCCCAACGACGCGAAGGACAGCCTGACGgtggaggcggcggcggcggcggctgcagcggccgcggccgccgcgggaCGGCCCACGCCTCTGATCTGCCCGCCGTGCGGCATCCGCTTCAGCTCGGCGAGCACGCTGGACGCCCACCAGAAGTACTACTGCTCGCACCGGCCGCGCCTCGAGACCGACGCCGAGAAcaacgacgaggacgacgacaaGGGCGCGCCGTCGGCCGGCTCGGCCGGCTCCGCGGTCAAGTTCGAGGCGCGCAAGGCCTACGCCTGCCCGCACTGCTCCTACAGCGCGGACAAGAAGGTCTCGCTCAACCGACACATGCGCATGCACGCCGCCTCGCCGGTCCAGCCGGTGCCGCCCGCCCCCGCCATGCAGCCCATCAACGCCGCCCCCGCGGCCGGACACAACGCCGTAGTCGCCGCCAACGGGAGCATCAACGACGAGCCCGAGAAGTACTGTCGGAACTGCGATATCAGGTTCAGCTCGCTAAAAACGTACCGGGCGCACAAGACGCACTACTGCAGCACGAGGCACGTGGTGAAGGACACCCCGACGGCGTCGACGCCGTCGGCGAGCACGGCCACCTCGTCCCTGAAAGGATCCCCGCCGACGAGCGCGAGTCCCGGcgactcgccgccgccgcagccctGCCTGGCCCTGCCGACCAACCCGATCATCATCGTGCCGTACTCGCTGGTGCGAGGCGCCTCGGTCCTCGCGGCCCCGGGCCTGCCCGCCCCCGACACCCCCTGCTTCCTCATGCCCAACGGCACCCTTCAGCCCATGACCCGCGGgcccaccaccaccaccaacACCCCCACGACGATCGTCTCGACCATCTCGGGGATGGAGTCGCCGGCGCCGACGCCCGTCGTCGCCCCCAGCGTCCTCAGGGCGGCCAACAAGCCCGCCACCCCCGTGGCGATCGGCCCGGCGCCCCCCAACTCGCCGAACTCGGCCGCCTCCGCGCCCCTGGATCTTAGCGTCAGGAGGTCACCGGACCACGAGAAGGAGAACCGAGTCTCGCCGCTGCCGtcgtcgctgccgccgccgggcAGCCCCCGTTCCCGCGGCAGCGTAAGTCCGCGCGCCAGGTCCATGTCGGCGGCGCAGGCGCCCGACCGGATTCCGCCCACGCCGCCCACCGAGCTGGCGCTTAGACTCGCGgaactgccgccgccgcccgttCCCGGCGTACTCGTCAAACAAGGCGTTTCCAGATGCAAGGAGTGCAACATTGTGTTCTGCCGTCACGAGAACTTCGTCGCCCATAAAAAGCACTACTGTCaagcgcgcgagagcagcgTGACGAGTCCACCGCCGCCGGATACGCCCTCGCCGCCCCTCGTCCAGTTGATTTGTGTCGCCTGCGGTATCAGGTTCGCCTCGATGGACAACCTCGTCGCCCATCAATCCTACTACTGTCCCAAGAGAACCGAGCCTCCGGATCATTCTTCGCGCTGCCCCAAATGCAAGGCGCCCATCGACGCAGCCACGCCGCACACCTGCGCCGTCGGACAGACCGGCGGCTGGAGATGTCCGGTTTGCGGAGCAGTCAGTCCCACTGCCGGCGCAGCTCAGCGACATATGGACTCCCATCAAGGTGTCAAGGCTTTTCGATGTACGATCTGTCGGTATAAAGGTAACACCCTCCGAGGGATGAGAACACACATCAGGATGCACTTCGAGAAGCGCGGGGCCGATCTTCAGGAGGAGAATTACATAACGTGTCTATTGGAGGACGACGTAACTGCCCCGACCCCAGAACCAGCACCGGCGACTACTCCCGAAGAAATCCCGTCGGacccgcagcagcagcagcagcagcagcagatcAACGGCAAAACCGATACCATCGTGCGCAAGAGTCCGCAACCTCCGCGGCCGGTTACAACGTCGCCGGCGGCTTCCCCCGCACCTACAGTTCCGTCGCCGACCAATTCCGGCAAAGTGAAACAGGAGCGCGAGGACACCCCACCCCCGCCACCGCCGGAGGAGAGCCTCGACGAATCGAAACCCGGGCCACGCTACTGTCGGTCCTGCGACATCAGCTTCAACTACCTGAGCACCTTCATAGCTCACAAGAAGTACTACTGCTCGAGTCACGCTGGCGAGGCCAGcaacaacaataacaataataacaacaaCAACGCAGCGGCCGCTTCTCCGGCACCGATGACCAGCGGAAGGACCGAGGCGTCCGTACTATAA
Protein Sequence
MVLLARRISGFKWEDEEWSDSEKTPSVSSGLEGCGSAVSSPSGQLVDEELVALPPPPRLSAAGLPTPDDVRLRLGALNDDVRKRLADEIENVRALRNQHHHQQHHHHHHQQRPPSRPPSVQDSSPKSRPEAADEDSNLAVREDERSASSSSSSSGSLRRGQALRRDSEESSRTRCPSAGDEVAEPKRPRLEEEAAAAATVAAPRLRLNASLATDPALRPQAVAALTIKPENAASPPNPTPPLAAGLQNAIATGHLFVLPNDAKDSLTVEAAAAAAAAAAAAAGRPTPLICPPCGIRFSSASTLDAHQKYYCSHRPRLETDAENNDEDDDKGAPSAGSAGSAVKFEARKAYACPHCSYSADKKVSLNRHMRMHAASPVQPVPPAPAMQPINAAPAAGHNAVVAANGSINDEPEKYCRNCDIRFSSLKTYRAHKTHYCSTRHVVKDTPTASTPSASTATSSLKGSPPTSASPGDSPPPQPCLALPTNPIIIVPYSLVRGASVLAAPGLPAPDTPCFLMPNGTLQPMTRGPTTTTNTPTTIVSTISGMESPAPTPVVAPSVLRAANKPATPVAIGPAPPNSPNSAASAPLDLSVRRSPDHEKENRVSPLPSSLPPPGSPRSRGSVSPRARSMSAAQAPDRIPPTPPTELALRLAELPPPPVPGVLVKQGVSRCKECNIVFCRHENFVAHKKHYCQARESSVTSPPPPDTPSPPLVQLICVACGIRFASMDNLVAHQSYYCPKRTEPPDHSSRCPKCKAPIDAATPHTCAVGQTGGWRCPVCGAVSPTAGAAQRHMDSHQGVKAFRCTICRYKGNTLRGMRTHIRMHFEKRGADLQEENYITCLLEDDVTAPTPEPAPATTPEEIPSDPQQQQQQQQINGKTDTIVRKSPQPPRPVTTSPAASPAPTVPSPTNSGKVKQEREDTPPPPPPEESLDESKPGPRYCRSCDISFNYLSTFIAHKKYYCSSHAGEASNNNNNNNNNNAAAASPAPMTSGRTEASVL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01111394; iTF_01112133; iTF_01113075; iTF_01113819;
90% Identity
iTF_01113819;
80% Identity
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