Basic Information

Insect: Ormyrus labotus
Gene Symbol: Aff4
Assembly: GCA_035582975.1
Location: JAWWEO010000001.1:11651020-11683056[+]

Transcription Factor Domain

TF Family: AF-4
Domain: AF-4 domain
PFAM: PF05110
TF Group: Unclassified Structure
Description: This family consists of AF4 (Proto-oncogene AF4) and FMR2 (Fragile X syndrome) nuclear proteins. These proteins have been linked to human diseases such as acute lymphoblastic leukaemia and mental disabilities [1]. The family also contains a Drosophila AF4 protein homologue Lilliputian which contains an AT-hook domain. Lilliputian represents a novel pair-rule gene that acts in cytoskeleton regulation, segmentation and morphogenesis in Drosophila [2].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.15 4.3e+03 -2.7 2.0 2 22 27 47 26 54 0.80

2 10 1 2.9e+04 -20.5 36.5 32 282 78 318 68 321 0.43

3 10 0.63 1.9e+04 -4.8 5.7 91 145 332 385 306 401 0.45

4 10 2.4e-11 7.1e-07 29.5 6.3 343 442 423 521 399 530 0.79

5 10 0.0035 1e+02 2.6 27.9 414 493 587 665 558 675 0.43

6 10 1 2.9e+04 -17.7 34.8 91 263 681 868 663 871 0.54

7 10 1 2.9e+04 -10.9 23.2 423 486 819 882 779 896 0.69

8 10 1 2.9e+04 -14.3 30.6 394 481 836 944 823 971 0.70

9 10 0.19 5.6e+03 -3.1 10.3 89 219 1125 1255 1085 1269 0.42

10 10 0.0027 80 3.0 8.2 124 190 1461 1527 1424 1568 0.58

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.15	4.3e+03	-2.7	2.0	2	22	27	47	26	54	0.80
2	10	1	2.9e+04	-20.5	36.5	32	282	78	318	68	321	0.43
3	10	0.63	1.9e+04	-4.8	5.7	91	145	332	385	306	401	0.45
4	10	2.4e-11	7.1e-07	29.5	6.3	343	442	423	521	399	530	0.79
5	10	0.0035	1e+02	2.6	27.9	414	493	587	665	558	675	0.43
6	10	1	2.9e+04	-17.7	34.8	91	263	681	868	663	871	0.54
7	10	1	2.9e+04	-10.9	23.2	423	486	819	882	779	896	0.69
8	10	1	2.9e+04	-14.3	30.6	394	481	836	944	823	971	0.70
9	10	0.19	5.6e+03	-3.1	10.3	89	219	1125	1255	1085	1269	0.42
10	10	0.0027	80	3.0	8.2	124	190	1461	1527	1424	1568	0.58

Sequence Information

Coding Sequence: atgtgtcgacaaattaatttaaaagtttcggaGGAGCAGCAACAAGCAGCTATCGATAGCATCATCGAAATCATGGAGGACCAAGACCGTGAACGCCTTCGCGAGCGGGAACGACAGGCCCGCGCGGCTATGTCGGCCCAAACGGACAACGCCTCGGTCCTGCCTACAGCTCCAGCTGTAAACGGGAGTAATAACCCTATGGTTGAGAATTCCGCGGATGATCCCGCCGAGTCCTTGTTTAATCCTCCGGTAAAGGTGGAACCCGAAGATCAGGACACTGCCATCAAGGAAATCGTCTCCCAGCTGGGGAACTTTGCCTACGTGCAAACGGTGCTAGCCTCGAAACCGAAATCATTCATAGGCACCATCGGCAACGAAGAGTCGGACAACCCCGACGATGACGAGGTTCCCGAGGAGGAGATCCTGAATCTGATGGAAGTAGACCCTTGCATGACGTCGAGCGCGGCCGGGACGACCTTCGTACCGAGACCCTCCAGATCCCGGGACTCTCCCTCGAACCCTCGGCCCTCGACGTCCCGCGGATCCCCCGGCAACCCGCGGGCCCCGACCTCGCGCAGATCCCCGGGCCACTCCAGGGCCCCAACCTCGCGCGGCTCGCCGTCCCACCACCGGCCGTCGACCTCGCGGGGCTCCCCCTCGCAGAGGAGGCCCTCGACCTCGTCCCGGCCCTCGTCGACCTCGTCGCGCGGCTCGCCAACGCCGAACCCGAGGCCGTCGACCTCCCAGACAAGGCCCTCGATGCCTCAGCGGCCGCCAGCCGGTCCTCAGGAGTTCAAGAAGCCGGGCGGCCCGAGCCGTTCCTCCGGCTCCTCCTCGCAGGGCTTCGGTCAGCCCTCGGCCACGtcgtcctcgtcctcctcgtcgtcgtcgtcgtcgtcgtcgggccCGAAACCGCCCAGCGGCGGCTTCGTCAAGCCCACTTCACAGAGGCCCGGCAGTTATCCGCATCAGAACCCCCAAGGCATGAAGCGGCCCTCCGGGCACGATCACCGGGTGCGCGGCCCGCCGCCCAAGCAGCGGCCCACCAAGGCGCCCGGCGGCCCGGCGCCGGTCGTCCCCGGGCCCAGCGGCATGCAGCAGCCCCAGCcgatgcagcagcagcagcagcagcagcagcagcagcagccgtcgAGCAGACTGCAGAACGCCGCGAGCCGAGTGCCGAAGCTGCCGCAACTTCCGCAACTTCCGCAGCTTCCAATTTTACCGATCACAAAAAACAGCGCGACTTCCAGGCATTTCAGAGCCGAGAGCACGGCGGAGGTGGAGACCATCCTCAAGGAGATGACGATGCCGCCCACACCACTGACGGCGATCGCTCAAACTCCGCGAAAGGAGCAGGAGTCCAAGTTCACCTTCAATCCGGTGCTGCAGAAGCTCACCGAAGTCAACGCGCCGGAGAGCAGGCCACAACAACACCCGATAATCAAGAGATCGACCCACAGGCTGTCTGCCGATTTGGAACGAGACTTGAGCCTGTCCGAAGACAGCGAGGACGAGGAGCCTGCGAAGGTACCGGCAGCGCCGCCCGCACCGGCGCCCATCCGTAATGAAATACCCAGGCCGCTGATCCCAACTATGGGCACGGCGCCGCCACCGTTGGCGCCGATGTCGCCGATGAGCTCCCCGTTGGGACCACAGGCATCGCCGCCCAGCACTGTGACGCAGCCGCCGTATGTCCCACCGCAGCCGTTGGCGCAGCCGATCGTggagcagcaacagcaacagcagcagcagcagcagcagcagcagcaacagctgCCGGCAGCGAGGCCAACGGCCCAGCCGGTGCCCGCAGCACCGTTAGTAAGCGACCAAAGACCGCCCAGCCCACCAGGCGAGGCACCCGCCAGCTCCGAGAGCGGCTCGTCATCCTCGGATTCAGGCTCGGACTCGGAATCGGACAGCAGCGATGACACCGAGGACGAGACTGAAAGCTCGACGACACAGCCGCAGACCAAGGGCCCCAGCACGCCACCTTCGGTCTCGCCGAACGGCGTTCAGCCCGAGGAGATACCACCAGCTGTCGAGGAAGCTAAGCAGCGCTGGAATCTGAGCTCGTTCTTCAACAAAGCGGAGCAGAAAACCGCCAAAAAGGACGAGCCAAAACCCGCACAAGTCGCGCAGCCGCCCGAAAGGCGCTCGTCGAGGCATTCGCAGCACCTCGATTGGGAGCACGACAGGAATAGAAATATAATCGGTAGCCTGAGTGACAACGAACACCAAAGCGATGTCGAAAAGGCTAAAGAGCCGCCGAGAAATACGatACAAGCAGACAAGCCAAAGGCACCTGACGTACGCAAACGTGGCCGACCACGTAAAACAGATAAACCACCAGCAATTGCGGCCGAAGACAAAGCTTCCGCGGCAGCTGGCAAGCGGCCGAAGCcacgaattaataaaaaagcaccAATTTCAAAGGCGGTACTGACGACAGAAAGCGAGAACAGCAATTCTCAGTCTTCAGATTCCGAATTTGACGCTGTAGTGAAACGGTCATCCTCACCATCAAAAAGGGCTAGCTCACCAAAACACCATAGATCATCACATCTGAGTCTTAGCTCCAGTGAGGATGATGACTCAAGCAGGGCCGATGATGTTAGTTCGAAAAAAGGACGCAAAAGTATGCGGGACGATGATCCGCATTGGAATCGAGCATCGGCGAAACGTAGCAAAAAAATCAAGGATGTTCCGAAAAAGATggcagaaaagaaaattcaaaagaaatcaCCCAAAGTCAAGAAAAGGCAGAGAAGTCGAGTGACGAGTGCGCCGGAATGTCCAACCGAATCGGATAGCGAATCGGAGGTAGCGATCCGGAaggtggCACGAGTTCAGCCCAGGCCACGAGCACCTATGCGGGCCACATCACCCGAAAATTCGGACAGTGACAACAGCCCAGTAGTTGGAAAAATTCAGGATGAAACTACTGGCACGGGtcaagataacaaaaaaagtgCATTACGTAGACTATTCGTTGATTCTCGTGCTAAAGGCGGTAAAGGAGGAAAGGGCGGAAAAGGTGGAAAAGGTGGTGCGAAGTGTGGGATCTATGTCGAGGAATATTCCTCAACCACGCCGATTCGTAGTCAAAGCCCTTTCAAACGTCCGCCTTCCACTGTGTTGCCAGCGCCAGCTGCATCAGCCCCACTAGCTGCAATATCGGAACGCCACGAAGAGAAAAAACTGACACTCCCGCCATTAATTTATGTGGACGGGATTCCTCGATTAATTTGCAGATTGAGTCTGAATAGGCTTAGTAACGTGCCTCAACCGTCTCGAGGGCAGGAGATCCGACAGAGAACCGAGATGCCTGACACCAGGCCATCATCGAGGTCTCAGAATATCATACCACGCCCTTTAACCCCGGAAGAGGGCGAAATCGTCGAAATGCCCACTGAAGAAAACGATTCGAcgctaaatataaaagaattttctgttAGCGACAACAGCAGTACCATTAGAAAAAGTAACAGCCACGCAGTGAAAAGCGCCAAAAGCCTGGACgctaaaaaaagtgaatttaaatCAGATTCCATGACACTCGCGAGTGATAGTGTATGTGCTGGCAGTGGCAGTAACATTGATAATCTTATGAGTAACgtaacaaatgaaaataaaataccgcgtattaaaaaacgaaaacataAAAACTCTAGCAGTGAATCGCCAGCTTTATCATCATGTACAAGTAACGACGAAAGACCCAACAAAAGATTCTGTTCGACAAACCATGAGCGGGAAGACAGGCCAAACCTGCCACCGCTTCCTATGCCGCCTTCAAATAGGGTTTTCtactcatatttttatttaagagagGCGCAACAGCAAGAAGTCGATAGATACCACGAACATTATCTGGCGGAGGCAAAACGCTTAAAACATACAGCGGACGAAGAAAGAGACACGACGGCACAGGCGCTGCTCTATATGGAAGGagcagtttattttattttaactggGCAAGGAATGGAGTCATCCCCTGTTACAGAACGTGCCGCTTTTCGAATGTACAACGATActctatatataataaaGTTCATTGCGAACAAGTTTCAACAAATGCCAGATGATACACCAGAGAGCAATATCTATGTAAAATTGGTTGTGTTAAGCCTGTGGTCACAAAGCTTAATCTACCAGAAGTTATTCCGCTTAAAAAAGGcggaaattaaagaaaaccaCTCGATGTTAGCTGACTATTTCCAAAAAcAACTAATTCAACCTGAAGGCTTATTGACACCCTCAATATTAACGCCCTCATCTGTAGTAACCCCATCATTATCCCCGACGCCATCACCAGCAGGTTCTGTAGGATCAGTTGGCAGCGTAGGTTCAATGGGTTCAGGAAGCTCAGGGAACTCTGCTAACTCTGTTGCTACAAGTGTTACCAATTGCTCAGGAGCCTCAGGAGGTTCAATAAGCAGTGGTTACAGTAGTAATACGCAAatgcaacagcagcagcagtcacAAGAACTACAGCAACAAATTCAGCCACAGCAGCAACATCAACAACTGCAACATCCTGCGCATCAtcaacaacagcaacaacaacaaagtTTTATCACTATTCCTTTGAATGTATATACGGCGCTGCAAAAGCAACACACGGATATGGAATATCTGATAAACGCTACCGATAGTTGGATTGAAGCATGTGACCTAGTTTCGGAGAAGCATCGAGAATTCTTCATTGCGCTGGACGAGGAGTTGGGTCCTTTAACCCCTCAAAGTTCACTAACCGAGCTGGTGCGTTACGTGCAAGTAGGCATTAAAAAGTTACGTAAGCTGTGA
Protein Sequence: MCRQINLKVSEEQQQAAIDSIIEIMEDQDRERLRERERQARAAMSAQTDNASVLPTAPAVNGSNNPMVENSADDPAESLFNPPVKVEPEDQDTAIKEIVSQLGNFAYVQTVLASKPKSFIGTIGNEESDNPDDDEVPEEEILNLMEVDPCMTSSAAGTTFVPRPSRSRDSPSNPRPSTSRGSPGNPRAPTSRRSPGHSRAPTSRGSPSHHRPSTSRGSPSQRRPSTSSRPSSTSSRGSPTPNPRPSTSQTRPSMPQRPPAGPQEFKKPGGPSRSSGSSSQGFGQPSATSSSSSSSSSSSSSGPKPPSGGFVKPTSQRPGSYPHQNPQGMKRPSGHDHRVRGPPPKQRPTKAPGGPAPVVPGPSGMQQPQPMQQQQQQQQQQQPSSRLQNAASRVPKLPQLPQLPQLPILPITKNSATSRHFRAESTAEVETILKEMTMPPTPLTAIAQTPRKEQESKFTFNPVLQKLTEVNAPESRPQQHPIIKRSTHRLSADLERDLSLSEDSEDEEPAKVPAAPPAPAPIRNEIPRPLIPTMGTAPPPLAPMSPMSSPLGPQASPPSTVTQPPYVPPQPLAQPIVEQQQQQQQQQQQQQQQLPAARPTAQPVPAAPLVSDQRPPSPPGEAPASSESGSSSSDSGSDSESDSSDDTEDETESSTTQPQTKGPSTPPSVSPNGVQPEEIPPAVEEAKQRWNLSSFFNKAEQKTAKKDEPKPAQVAQPPERRSSRHSQHLDWEHDRNRNIIGSLSDNEHQSDVEKAKEPPRNTIQADKPKAPDVRKRGRPRKTDKPPAIAAEDKASAAAGKRPKPRINKKAPISKAVLTTESENSNSQSSDSEFDAVVKRSSSPSKRASSPKHHRSSHLSLSSSEDDDSSRADDVSSKKGRKSMRDDDPHWNRASAKRSKKIKDVPKKMAEKKIQKKSPKVKKRQRSRVTSAPECPTESDSESEVAIRKVARVQPRPRAPMRATSPENSDSDNSPVVGKIQDETTGTGQDNKKSALRRLFVDSRAKGGKGGKGGKGGKGGAKCGIYVEEYSSTTPIRSQSPFKRPPSTVLPAPAASAPLAAISERHEEKKLTLPPLIYVDGIPRLICRLSLNRLSNVPQPSRGQEIRQRTEMPDTRPSSRSQNIIPRPLTPEEGEIVEMPTEENDSTLNIKEFSVSDNSSTIRKSNSHAVKSAKSLDAKKSEFKSDSMTLASDSVCAGSGSNIDNLMSNVTNENKIPRIKKRKHKNSSSESPALSSCTSNDERPNKRFCSTNHEREDRPNLPPLPMPPSNRVFYSYFYLREAQQQEVDRYHEHYLAEAKRLKHTADEERDTTAQALLYMEGAVYFILTGQGMESSPVTERAAFRMYNDTLYIIKFIANKFQQMPDDTPESNIYVKLVVLSLWSQSLIYQKLFRLKKAEIKENHSMLADYFQKQLIQPEGLLTPSILTPSSVVTPSLSPTPSPAGSVGSVGSVGSMGSGSSGNSANSVATSVTNCSGASGGSISSGYSSNTQMQQQQQSQELQQQIQPQQQHQQLQHPAHHQQQQQQQSFITIPLNVYTALQKQHTDMEYLINATDSWIEACDLVSEKHREFFIALDEELGPLTPQSSLTELVRYVQVGIKKLRKL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -