Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 1.3 5.3e+02 0.9 0.0 22 49 74 101 70 104 0.76

2 9 0.056 22 5.3 0.1 20 44 100 124 93 128 0.87

3 9 0.023 9.1 6.5 0.0 21 46 129 154 124 161 0.89

4 9 0.45 1.8e+02 2.4 0.0 21 46 157 182 153 188 0.89

5 9 1.6 6.1e+02 0.7 0.0 23 52 187 216 182 218 0.83

6 9 8.3 3.3e+03 -1.7 0.0 22 43 214 235 211 244 0.73

7 9 0.64 2.5e+02 1.9 0.1 21 44 241 264 233 268 0.85

8 9 0.00018 0.072 13.2 0.2 22 52 270 300 266 302 0.89

9 9 1 4e+02 1.3 0.0 23 45 299 321 296 324 0.88

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	1.3	5.3e+02	0.9	0.0	22	49	74	101	70	104	0.76
2	9	0.056	22	5.3	0.1	20	44	100	124	93	128	0.87
3	9	0.023	9.1	6.5	0.0	21	46	129	154	124	161	0.89
4	9	0.45	1.8e+02	2.4	0.0	21	46	157	182	153	188	0.89
5	9	1.6	6.1e+02	0.7	0.0	23	52	187	216	182	218	0.83
6	9	8.3	3.3e+03	-1.7	0.0	22	43	214	235	211	244	0.73
7	9	0.64	2.5e+02	1.9	0.1	21	44	241	264	233	268	0.85
8	9	0.00018	0.072	13.2	0.2	22	52	270	300	266	302	0.89
9	9	1	4e+02	1.3	0.0	23	45	299	321	296	324	0.88

Coding Sequence: ATGGGAGACTTGGAACTGATAGAAGATTCAAAGATGAAAGAGGAGTGTATTGAAAGCCATAGAGAAGAAGTGTTAATAAAGGAGGAACCAATCGAATTTAAGGAAGAACCTGATGACGTGGAACCGGAGGTTTTTGAAAACGTCGATCCTAAAAATGAAGAAAATTCTGTCTGGAGCAAATTTTCTTTTTGGAGCGACCTAATGGAAAGCGATGGAACAGAAAAACACTTTAATTGTTCAACATGTCAGCAGAAATTCACAAATGCTGATGATTTGAGGAAACATGCCGAAGAACATAATGCTGAAAAGCCGTTTGGTTGCGAAATTTGCCAAAAGACGTTTTCGCAAGCTATCCATTTGAAGAACCATACTCGAATCCATACGGGGGAGAGGCCTTATGGGTGTGAAGTGTGCGAAAAAAAGTTTCATTCGTCCAGCGATTTAAGAAAGCATTTTAAAATCCATACTGGCGAGAGACCATACGGGTGTGAAACGTGCGGAAAAAAGTTCATATCGAGCAGCAATTTGAGTAAACACATCAAAATCCATACTGGAGAAAAGCAATACGGATGTGACGTCTGCGGTAAGAAGTTTACACAACACAGCAGCCTGAAGACGCACATAAAAATCCACACCGGGGAAAAACCCTACGTCTGCGTAATGTGCGATAAAAGGTTCATTTTAGCCTGCGATTTGAAAAAGCACGTTTTCACCCATACCGGAGAAAAGCCGTACGAGTGCCAAATATGCGAAAAAAGATTCGTTTCTGCCAGCAATTTAAGCGAGCATGTCAAAACTCATGGCGGAGAAAAGCCGCACGTTTGCGCTATTTGCCTAAATGCGTTTACGAGGGCTAATAATTTGAGGACGCATATGAAAATTCATTTGGGAGTGAAGCCTTATGTTTGTGCAGTCTGTAATATGGGGTTTACAAGGGATGATAGTTTGAAGAGACATATGAAAACCCACAGGGATTGA
Protein Sequence: MGDLELIEDSKMKEECIESHREEVLIKEEPIEFKEEPDDVEPEVFENVDPKNEENSVWSKFSFWSDLMESDGTEKHFNCSTCQQKFTNADDLRKHAEEHNAEKPFGCEICQKTFSQAIHLKNHTRIHTGERPYGCEVCEKKFHSSSDLRKHFKIHTGERPYGCETCGKKFISSSNLSKHIKIHTGEKQYGCDVCGKKFTQHSSLKTHIKIHTGEKPYVCVMCDKRFILACDLKKHVFTHTGEKPYECQICEKRFVSASNLSEHVKTHGGEKPHVCAICLNAFTRANNLRTHMKIHLGVKPYVCAVCNMGFTRDDSLKRHMKTHRD

Sequence clustering based on sequence similarity using MMseqs2