Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.26 1e+02 3.1 2.5 25 47 41 62 33 66 0.74

2 10 0.0036 1.4 9.1 0.2 21 46 65 90 61 97 0.86

3 10 0.65 2.6e+02 1.9 0.0 21 52 93 124 89 125 0.85

4 10 0.49 1.9e+02 2.3 0.0 21 45 121 145 108 152 0.83

5 10 0.093 37 4.6 0.0 21 46 149 174 145 180 0.89

6 10 5.2 2e+03 -1.0 0.1 27 45 182 200 179 208 0.76

7 10 0.37 1.5e+02 2.6 0.0 22 44 211 233 200 237 0.85

8 10 0.028 11 6.2 0.0 21 46 238 263 233 268 0.90

9 10 0.41 1.6e+02 2.5 0.1 22 46 267 291 262 293 0.86

10 10 0.0075 2.9 8.1 0.1 21 46 294 319 290 321 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.26	1e+02	3.1	2.5	25	47	41	62	33	66	0.74
2	10	0.0036	1.4	9.1	0.2	21	46	65	90	61	97	0.86
3	10	0.65	2.6e+02	1.9	0.0	21	52	93	124	89	125	0.85
4	10	0.49	1.9e+02	2.3	0.0	21	45	121	145	108	152	0.83
5	10	0.093	37	4.6	0.0	21	46	149	174	145	180	0.89
6	10	5.2	2e+03	-1.0	0.1	27	45	182	200	179	208	0.76
7	10	0.37	1.5e+02	2.6	0.0	22	44	211	233	200	237	0.85
8	10	0.028	11	6.2	0.0	21	46	238	263	233	268	0.90
9	10	0.41	1.6e+02	2.5	0.1	22	46	267	291	262	293	0.86
10	10	0.0075	2.9	8.1	0.1	21	46	294	319	290	321	0.90

Coding Sequence: ATGGAAGATATTAAAGAAGACATGATGGAAACAAAAGAAGAGACGTCTGAGAAAGGCGAAGAAGAGCTCGAAGATACTCAAGACTCACAAGAGGAAGACATAGGCCAGGGATCATCACGTAATGAATGTTCAATCTGCTATAAGCAATTCAGCAGGCATTGCCATCTTATAAGGCATTTGAGAAGACATGTAGGTGATAAGCCCCACACGTGCGAGGTGTGCCAAAAAGGTTTTACGCAATCGGCAAGTCTTAAGAACCACATGCGGATACATACAGGAGAGCGGCCGTATAGCTGCGAGATGTGCGATAAAAGTTTTACCGACCCGAGCACTCTTCGAGGGCATATGAGGATACACAATGGAGACAAGCCGTTTAGCTGCGACGTCTGCGATAAAAAGTTCAGCCTTTCAAGCACGTTGAGGGACCATATGAGAAACCATACTGGAGAGAAGCCTTTTAGCTGCGAAGTCTGCGGGAAGAAGTTTACCAACGCCAACAGCCTTAGGAAGCACATAAGCATCCATATTGGAGAAAAGCATTGCTGCGATTACTGCGATAAGACTTATACCGATCCTAGTAGTTTAAGAAGGCATATGAAGACTCACGAGGAGTACGTCCAAGGTAAAATTGAAAAGATGTACAGCTGCGATGTCTGCGAGAAGAAGTTTACGTATTCGCATAATTTGAGGGTCCATAAACGTATTCATACTGGGGAGAAACCATATAGCTGTGATGTCTGCGAAAAGACGTTTACAGATTCAAGCACAATGAAGAGACATATGAGCGTCCATGTTGAAGAAAAACTCTATACGTGCGAGGTCTGTGAAAAGAAGTTCGCTCATCCTTACGATTTGAAGAGACACCTTCGGATCCATACTAAAGAGAGACCGTTCACTTGTGAAATCTGCAATAAAAATTTTACCCATCCTGGCAACCTAAGCAGACATAAAAGCTTACATTCGAGATAG
Protein Sequence: MEDIKEDMMETKEETSEKGEEELEDTQDSQEEDIGQGSSRNECSICYKQFSRHCHLIRHLRRHVGDKPHTCEVCQKGFTQSASLKNHMRIHTGERPYSCEMCDKSFTDPSTLRGHMRIHNGDKPFSCDVCDKKFSLSSTLRDHMRNHTGEKPFSCEVCGKKFTNANSLRKHISIHIGEKHCCDYCDKTYTDPSSLRRHMKTHEEYVQGKIEKMYSCDVCEKKFTYSHNLRVHKRIHTGEKPYSCDVCEKTFTDSSTMKRHMSVHVEEKLYTCEVCEKKFAHPYDLKRHLRIHTKERPFTCEICNKNFTHPGNLSRHKSLHSR

Sequence clustering based on sequence similarity using MMseqs2