Basic Information

Insect: Orchestes rusci
Gene Symbol: Hr39
Assembly: GCA_958502075.1
Location: OY293308.1:18414175-18439341[+]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 2 5.7e+04 -5.8 7.0 125 158 192 225 70 265 0.46

2 5 0.61 1.7e+04 -3.6 4.1 46 112 203 274 175 302 0.46

3 5 5.2e-09 0.00015 23.0 0.0 1 29 394 422 394 432 0.86

4 5 0.099 2.8e+03 -1.0 0.0 93 119 461 484 438 499 0.74

5 5 3.9e-72 1.1e-67 230.9 0.6 201 408 514 721 455 721 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	2	5.7e+04	-5.8	7.0	125	158	192	225	70	265	0.46
2	5	0.61	1.7e+04	-3.6	4.1	46	112	203	274	175	302	0.46
3	5	5.2e-09	0.00015	23.0	0.0	1	29	394	422	394	432	0.86
4	5	0.099	2.8e+03	-1.0	0.0	93	119	461	484	438	499	0.74
5	5	3.9e-72	1.1e-67	230.9	0.6	201	408	514	721	455	721	0.89

Sequence Information

Coding Sequence: ATGTCAGCCGAAATGCGCTCGCCCAACGTATCCGTCACACCCATCAACATGGAATACATTCCATCGACCAATGGCACGCCAGATGGCTCGGTTATCAGCACTGTGGGTGTGCCCGAGCCACCAAGGACTCGTAGTGCGCCACACCCCCAAGTGGTTTTAGCGAATGGGATGGCCGATGTAGATGGACCTGATCCAGAACTAGCTAGGATAGACTTTCAGAGTGTAAATATGCGGAGCAAGAAGAATCAAGAAGAGATGCCTCGACCTATGAGCTGGGAGGGAGAGTTGAGTGATGGGGAAAGAGAGGGCATGTGTATAGATGAGAGTAGTGAACCACCACATTTGCCAGAGAACTTATCACTATCAGCCCCTAAACAAACTACCTTTGACTTGAAAGATAGTCCTATTTTAAGACTAAAACAGCCTCCTGTTAGCAGTTATTCATTGCACAGTACTCCGTCGAATTCGCCATTATTAAATCAACGACATCCTGGAACTGCTGTGCCCATCATTAGCCATAAGgatctcaTGCAAAAAGCACTGAACATCCCACCTACGCCCAGTCCAGACTCAGCTGTACATTCAGCGTACTCGGTCTTCAGCTCGCCCAATCAAAGTCCTCTGACACAAAGGCATGTGACTTTGACGCCGAATCTGAGCAGAAATAATTCAGATGCCTCGCATTCGAGTTGTTGTAGTTACTCGAGTGTCTCAGTGTCAGTTTCTCCCACCCAACAATTTTCGCCTACTCACAGTCCCATACAGGGCCGTCACATACACAACTCTTTACATGGAAGTCCCCTGCACCATGGTGTCCTCTACAGAAGTCTTCCAGAAGATACCTCCTCCCTACAATCGCAATACGATCATGATCCAAGTGTGGGAGATGATAATGATGAAAAAACTGGGCTGTTGCATGCTGCTTTACCGGCTCAACCTGGTATATCAAGACAACAACTCATTAACAGTCCATGCCCTATTTGTGGCGATAAGATATCAGGATTCCATTATGGCATTTTCAGTTGTGAATCGTGTAAGGGATTCTTCAAAAGAACGGTCCAGAATCGAAAAAACTATGTTTGTCTACGAGGCGCCCAATGTCCGGTTACAGTGGCAACTCGAAAAAAATGTCCAGCTTGTCGGTTTGACAAGTGCCTCCAGTGCGGCATGAAACTAGAAGCGATTAGAGAGGACAGGACTAGAGGTGGCAGGTCCACTTACCAGTGCTCGTACTCCCTACCGCCCTCTTTAGCTTCGCAAACTGAGTTGAGAGCCAGTACAACAGATCTAAGGCATGGTTTTGGAGACCACCATCCCGGCTTCACGATAAAACTAGAACCACAAGATGGTGTTCTCGGACACCATCGACGAAGTCACATGCCTGGATCCAAGGGTGTCCCGCCACTATTGCAAGAAATAATGGACGTGGAACATCTATGGCACTACAACGAAGCTGAGTTGAATAAACTCAGCACAGAGGGACACCTAAGCAAAGAGGGCGCATCAGGCGCAGTGCATAATTTGTCCAACCACCCTCTGCTCGCCAAAACGGCACTTGCCGGATCGAACGACACCAATCCGGACTTTGTGGCCAATTTGTGCAATATTGCCGATCATCGGTTGTATAAGATTGTAAAGTGGTGCAAGAGTCTGccactattcaaaaatatatcgATCGATGACCAAATCTGTCTTCTCATCAACTCGTGGTGTGAGCTCCTCCTATTTTCCTGTTGTTTTCGGTCTATGGCGACTCCAGGTGAAATCCGCATATCACTGGGAAAAAGTATAAATCTGGCGCAGGCGCGAGATATGGGCATGCAGGCTTGCATAGAGCGCATGCTCAATTTCACGGAGCAGCTAAGACGGTTAAAAGTGGACCAGTATGAGTATGTTGCAATGAAAGTTATTCTTTTGTTGACTTCAGATACTTCTGAATTGCATGAAGCTGAGAAAGTAAGAGAATCACAAGAAAAAGCACTTAAAGCACTGCAGGATTATACATTATCACATTATCCCGAAAGTCCTGCCAAATTTGGAGAGCTGTTGTTACGGATACCCGAATTGCAAAGGACTTGTCAGGTCGGCAAAGAATTGCtaacaatcaaatcaaaagaCGGAGATGGCTTCAATCTCCTGATGGAGCTCCTCAGGGGCGACCACTGA
Protein Sequence: MSAEMRSPNVSVTPINMEYIPSTNGTPDGSVISTVGVPEPPRTRSAPHPQVVLANGMADVDGPDPELARIDFQSVNMRSKKNQEEMPRPMSWEGELSDGEREGMCIDESSEPPHLPENLSLSAPKQTTFDLKDSPILRLKQPPVSSYSLHSTPSNSPLLNQRHPGTAVPIISHKDLMQKALNIPPTPSPDSAVHSAYSVFSSPNQSPLTQRHVTLTPNLSRNNSDASHSSCCSYSSVSVSVSPTQQFSPTHSPIQGRHIHNSLHGSPLHHGVLYRSLPEDTSSLQSQYDHDPSVGDDNDEKTGLLHAALPAQPGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCLRGAQCPVTVATRKKCPACRFDKCLQCGMKLEAIREDRTRGGRSTYQCSYSLPPSLASQTELRASTTDLRHGFGDHHPGFTIKLEPQDGVLGHHRRSHMPGSKGVPPLLQEIMDVEHLWHYNEAELNKLSTEGHLSKEGASGAVHNLSNHPLLAKTALAGSNDTNPDFVANLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSMATPGEIRISLGKSINLAQARDMGMQACIERMLNFTEQLRRLKVDQYEYVAMKVILLLTSDTSELHEAEKVRESQEKALKALQDYTLSHYPESPAKFGELLLRIPELQRTCQVGKELLTIKSKDGDGFNLLMELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01240932;
90% Identity: iTF_01107672;
80% Identity: iTF_01107672;