Basic Information

Insect: Ophraella communa
Gene Symbol: topi
Assembly: GCA_035357415.1
Location: CM068992.1:14343420-14350091[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.0022 0.8 12.6 2.1 2 21 103 122 102 123 0.94

2 14 4.8e-06 0.0018 21.0 2.4 1 23 149 171 149 171 0.98

3 14 0.0086 3.1 10.8 2.1 2 23 178 199 178 199 0.95

4 14 0.024 8.8 9.4 0.1 2 20 218 236 217 238 0.90

5 14 0.0028 1 12.3 0.9 2 23 290 311 289 311 0.97

6 14 7.7 2.8e+03 1.5 0.0 1 11 317 327 317 333 0.88

7 14 0.0024 0.87 12.5 3.4 2 22 354 374 353 377 0.88

8 14 0.0011 0.41 13.6 0.1 1 23 484 507 484 507 0.94

9 14 0.0071 2.6 11.0 0.1 1 23 511 533 511 533 0.96

10 14 7.1e-07 0.00026 23.6 2.4 1 23 539 561 539 561 0.98

11 14 0.02 7.3 9.6 0.1 1 23 567 592 567 592 0.96

12 14 0.07 25 7.9 2.9 1 23 598 620 598 620 0.86

13 14 4.4e-06 0.0016 21.1 0.3 1 23 626 648 626 648 0.98

14 14 1.4e-05 0.005 19.6 0.8 1 23 654 677 654 677 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.0022	0.8	12.6	2.1	2	21	103	122	102	123	0.94
2	14	4.8e-06	0.0018	21.0	2.4	1	23	149	171	149	171	0.98
3	14	0.0086	3.1	10.8	2.1	2	23	178	199	178	199	0.95
4	14	0.024	8.8	9.4	0.1	2	20	218	236	217	238	0.90
5	14	0.0028	1	12.3	0.9	2	23	290	311	289	311	0.97
6	14	7.7	2.8e+03	1.5	0.0	1	11	317	327	317	333	0.88
7	14	0.0024	0.87	12.5	3.4	2	22	354	374	353	377	0.88
8	14	0.0011	0.41	13.6	0.1	1	23	484	507	484	507	0.94
9	14	0.0071	2.6	11.0	0.1	1	23	511	533	511	533	0.96
10	14	7.1e-07	0.00026	23.6	2.4	1	23	539	561	539	561	0.98
11	14	0.02	7.3	9.6	0.1	1	23	567	592	567	592	0.96
12	14	0.07	25	7.9	2.9	1	23	598	620	598	620	0.86
13	14	4.4e-06	0.0016	21.1	0.3	1	23	626	648	626	648	0.98
14	14	1.4e-05	0.005	19.6	0.8	1	23	654	677	654	677	0.98

Sequence Information

Coding Sequence: ATGAACACCCTTGATAATAATACGATTATAAAGGTATATAGAATTGAAGAAAATGGAATGGCGTCATCAGGAATGTGGTATGAAATGAATTCGAGTAGCAAAGTACCTATTTCTTCGAATAGCTTTTGTCCAGTAAACGTAAGCTTCGATCCCAATATATTAAAAGCTAACGAAAATAAGCTTacgttgaatttaaataaatttgatgtAAATAATGTGTTCGTTAAATGTATTAAGTTTGAAGATAGTTATGAGTCTTCGTCGTCAAATGTGGGTaagacaattttaaatattcctaCTATGATAAGATGCCAAAATTGCGAAACTAATTTTCCGACCAAGTATCAATATCAAAGACACCAGTGCGAATTTAATGCTGAAAAAGTTGTCCTAAAAGCCGATCCAGATTCTAATGAAGATAACACTGCTGAGGCACCAGTGAAATTCGTTTGtaaattttgcaataaacaGTTTGTAAATAAGAATAATTTAGCTCGTCATCAAACCAGCCACGGAAACACTCAAGAAAATGTTTGTGAACATTGCAACAAACAATTTATCAGCGAAAACCGTCTGAGGATCCACAAAGAAAATCATTGTAAAAAAGCTGGAGacatatctaaattttatagAAGCGATGTGGCCGTGTGGAAATGCAGAAAATGTTGGGAAGTGTTTTCGTCACCTTCAACTGCAAATTACCACGTGCTTTCTTGTACTGAAGTCgtagaatcagaaaatgatacgAAAAATACGGCGCAATCGCAGTTGGAAGATAAAAGTACCTTGACCTACAAGAACAACAATACTACGAGAGATTCAAGCGATAATAAAAATATCGAAAAAGTTTTAACCGAACTTCTACTACAATGTGAATTTTGTAACAGGACTTATGCCGAGAAAAACGTCCTACTTATGCACCAAAGAAAACATACCACCGCCAAAAACTACGAATGCGTTAATTGTTCTCTAGTTTTCGATTCCTACCTCGTCGCCGCCCAACATTGGATGAAAAAATGTTCGGAATCCGTGAGTCTATTCTACCTACCGAAATTAACTTACTGCGAATACTGCGACAGAACATTTAAATCCCACGAACTTTTATATACTCACAAGATAAAAAAGAAACATTACACCTCTAAGCTCCATCTAAAAACGACTGACGAAACTAATAAAGAAGTCGTCGAAAAACCCGCCGCCGAACAACAAACTGTCGATAATAAAGAAATCTTGAATAAGCTTATCGAAGAcgttttaaaaactttagaCGTTCCCGTTAATAAAATCAACTACCAAGGAGTAGAGAACAATAAGGAAACGTGTAACAAGAATGAAAATTGCGCGCCCGAACCAACGGAGAAGAAAAAGAGAGGCAGAAAACGAAAATGGCCGAAAAATCAGTGCTTGAGATCGAAAAAAGTAAACCTTGAAATCGACGATGGCTACAAGTACCAATGCGAAAGGTGTGTCAAGATATTCGTAACCGTAGATGAACTTGAGGCGCATCGGGACAATGAGCATGCTTCGAATTTCGCTTGCGACGAATGCGGACAGGTTGTTCATAGTGCCAAAGCTTTGATGATACACAGTCGAGCTCATAAAATGTTGAAACCGTACGTGTGTGAAACTTGCGGGCGCAGTTATTCCCAAACCTCTCATCTTTGGCAACATATGCGCTTCCATCAAGGAATTAAGCCGTTCGCGTGTCCTCACGAGGGTTGCGAAGCAAGGTACACCATCAGGCCGGATTTGAAGGATCATATCAGGAAAGCACATACCAGAGAACGTCCTTTCAAGTGCAACGTGTGTGATAAATGCTTTTTAACCGGATCCGTTTATTATCAGCATCGTTTGATACATACCAACGATAGAAGATACGCTTGTGACTTGTGTCCGAAAAGGTTTTTCAGAGCCGATGCTTTGAACAATCATCGAAGGATACATACAGACGAGCGTCCATATCCTTGTCGGGTTTGCGGGCGAGAATTTAGACAGAAAGGGGATCGTAATAAGCATGTCAGGACCCAGCATCCAGATACCGTTCTagtgtaa
Protein Sequence: MNTLDNNTIIKVYRIEENGMASSGMWYEMNSSSKVPISSNSFCPVNVSFDPNILKANENKLTLNLNKFDVNNVFVKCIKFEDSYESSSSNVGKTILNIPTMIRCQNCETNFPTKYQYQRHQCEFNAEKVVLKADPDSNEDNTAEAPVKFVCKFCNKQFVNKNNLARHQTSHGNTQENVCEHCNKQFISENRLRIHKENHCKKAGDISKFYRSDVAVWKCRKCWEVFSSPSTANYHVLSCTEVVESENDTKNTAQSQLEDKSTLTYKNNNTTRDSSDNKNIEKVLTELLLQCEFCNRTYAEKNVLLMHQRKHTTAKNYECVNCSLVFDSYLVAAQHWMKKCSESVSLFYLPKLTYCEYCDRTFKSHELLYTHKIKKKHYTSKLHLKTTDETNKEVVEKPAAEQQTVDNKEILNKLIEDVLKTLDVPVNKINYQGVENNKETCNKNENCAPEPTEKKKRGRKRKWPKNQCLRSKKVNLEIDDGYKYQCERCVKIFVTVDELEAHRDNEHASNFACDECGQVVHSAKALMIHSRAHKMLKPYVCETCGRSYSQTSHLWQHMRFHQGIKPFACPHEGCEARYTIRPDLKDHIRKAHTRERPFKCNVCDKCFLTGSVYYQHRLIHTNDRRYACDLCPKRFFRADALNNHRRIHTDERPYPCRVCGREFRQKGDRNKHVRTQHPDTVLV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00736063;
90% Identity: -
80% Identity: -