Basic Information

Transcription Factor Domain

TF Family: PC4
Domain: PC4 domain
PFAM: PF02229
TF Group: Unclassified Structure
Description: This domain is found at the C-terminal end of Activated RNA polymerase II transcriptional coactivator p15 from humans, YdbC from Lactococcus lactis, and other PC4 family members. p15 has a bipartite structure composed of an N-terminal regulatory domain and a carboxy-terminal cryptic DNA-binding domain [1-4]. Activity is controlled by protein kinases that target the regulatory domain.
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 5.5e-16 5.5e-11 44.2 0.3 1 36 42 77 42 80 0.97

2 3 0.24 2.4e+04 -2.7 0.0 23 35 108 120 108 121 0.82

3 3 0.55 5.6e+04 -3.9 0.0 13 23 219 229 218 230 0.65

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	5.5e-16	5.5e-11	44.2	0.3	1	36	42	77	42	80	0.97
2	3	0.24	2.4e+04	-2.7	0.0	23	35	108	120	108	121	0.82
3	3	0.55	5.6e+04	-3.9	0.0	13	23	219	229	218	230	0.65

Coding Sequence: ATGCCTAAAAAGTCAAAGAAGCAAGATACTTCTGATTCAGATTCCGGTCCGGAAGATgCAGCTCCAGCCAAGAAATCAAAGACTGAAACAAAATCATCAAAATCAAGTGAAGAAGAAAACTCCTGGAGTTTGGGCAAAAATCGCTTTGTAAAACtaacagaatttaaaaatacttggTACATTAACATTCGTGAGTACTATAATTCTGATGGGGAACTGAAACCAGGAAGATATACATTGTCGATAAAGTTCATAACACACGACAATCCAAATTACTATAATCCAAATTATCGAGCAACTAAATATATTGAAGAAATAGATAGAATCGTATTCACGGATGAAGAAAAAGCGAAGCCTTCAGGAGCTCTATATAGGGAACGCCAATTCACCCTAAATGAACACCCAGACGAAGACATGGACTTCACAGATCAAGTAGAAGACGAAATCGAAGACTTCGACGAAGAAATAGAGGACGGAAACTTGGGATTCACAACACCAAAAGAAGTAGCCTACACAATAAAAGGAAGGAAAGCCAGAAAAGCTCCCGGATACGACGGCATCAACCACAATGCACTGAAGCATCTACCAAGAAAATGGATAGTGTTTCTGACAACGATCATAAACGGAATACTAAGAACAAAGCACTTCCCGGACCAATGGAAGGAAGCAGAAATAGTCATGCTAAGGCAATCAGGACAAGATCCcaagtttccacaaaactacagacccatcagcctaCTACCAGCGATGAGCAAAATAGCCGAGAGAGTCATCCTCAAGAAGCTAAACGAGGAAACCGAAGCAATAGGAATACTGCCACAAGAATAG
Protein Sequence: MPKKSKKQDTSDSDSGPEDAAPAKKSKTETKSSKSSEEENSWSLGKNRFVKLTEFKNTWYINIREYYNSDGELKPGRYTLSIKFITHDNPNYYNPNYRATKYIEEIDRIVFTDEEKAKPSGALYRERQFTLNEHPDEDMDFTDQVEDEIEDFDEEIEDGNLGFTTPKEVAYTIKGRKARKAPGYDGINHNALKHLPRKWIVFLTTIINGILRTKHFPDQWKEAEIVMLRQSGQDPKFPQNYRPISLLPAMSKIAERVILKKLNEETEAIGILPQE

Sequence clustering based on sequence similarity using MMseqs2