Basic Information

Insect: Ophonus ardosiacus
Gene Symbol: egg
Assembly: GCA_943138245.1
Location: CALPBP010000163.1:72988-87928[-]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 5.2e-12 3.7e-08 34.5 0.1 5 70 661 719 658 725 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	5.2e-12	3.7e-08	34.5	0.1	5	70	661	719	658	725	0.90

Sequence Information

Coding Sequence: atgccAAGAACAGTTAGCACTCATCACGAAGAGGATGACGTAATAGTGCTCGACAACAATGAGGGAAGCAATAGTTCTAATCCCACAGAAGTGATAGATTTGGATAACTATGACGTCACtggcaaaaagaaaaaaaagcgAGCGTCTTGGAACAACTGCATCAACATAGAATGTGAAAATGGCGCCAATTTACGCGCGGCGAcaattttttgcttaaattacTACAGAGTTAAAATAAAACCCACCAAAAACCAAGAAGTCTGCGAGGAATGTTACGAAAAATCAGTTATTTATTACGAAAAGCTGTCTCAGTGTTTGAAAAATGGCGACACTCTCATTGAACAAGAATTGCCACAAAACGACGAATTTGTCGAAATCGATTCAGATTCAGACAGCGAAGCAAATATTGTTGATGTGTGTGTTGACGGGGTAACCGCTTGTCAAATATCCGACGATTGCTTTGACTTTTTGGCCAAAGAACTCCCATCAACTATGGATTCAGTTTTGCGTAAATACGATTTGGAAAAACAAGTGAACAACGCCGTGGCCGTCTTGGATGAAAAAGAACAACGTATTGAAAAAGGAATTGATGAAATGGTTGCTCTTGAGAAAGACTTGCAACAAAGAGTTGATAAATTACGATCAACTCTTTACGGAGAGttccaaaaaaaatatgagGAGTTACCTCCTGTTGAATTTACATTAATTTCGCCAAACAAAACAATGACTACTATGACGTCACCACCGAGAAAAGACCCCGAAAGGCGAAGCAACAGAAATATTATCAAACCGGCTAGCTATTGCGAACTAATGGACGATGACGTCCCATCACAAGATTTAACTTCAGATTTGGAGGTTACTCAAGAAATAGGGCCCCAAGAACGGTTTGAACTAGCGCCGCCTATTATTCCAGAAATAAACTTACCCCCAAGGGGGACTTTTCTTCGAACTCGGCCCCAAATTGGAAATTCCTACTACGCGCAACGTCAAAGTGTTTTTGGGGCTTGGGGCAAAGTTCATTTGCTAGATATCGATAATAGTTCAGGGAAATTGTTGTACAAAGTGAAGTTTGAAGGAAAAACAAAAGGGTTGAGTTCTATTAAGTTGGTAACGGGGAAACAATTGGCGTATTCCATGCCGACTGAAGTGAGGTTAGATGTTGGAACGCGAGTCATAGCTGTTTTTACAGATGAATCCACAATAAAAAAAGATTCCTTCTACGCTGGCCTTATCGCAGAACCACTCAGCCAACAAAACGACTGGCGCtatctcgttttctttgaagacGGCTACGCCCAGTACGTAAAACACgaaaaagttttagttatctgTGAGTGCAGCCTAAAAATTTGGGAAGATATCCATCCAGACTCgcaaaattttatcaaaaaatatttggagACCTACCCGGCTCGGCCTATGGTCAAAATTAAAACGGGGCAAGTCATGAAAACTGAGTGGAATGGAAGATGGTACTTTGCGAGGGTTTTGCGGGTCGATTGTAGTTTGGTGCATATGTATTTCGACGCGGACAATAGATCTGAATGGATTTATAGAGGAAGTACGAGATTGGGACCGCTCTTTTTAGAGTTCCAAGCTGCAACAGCTCGACAAGAAAAAGCACATCATATTCCTAAACTTCAACAGAAGCAAAATTCCAACAGTCCGCAGCCCTATGTCGAGTATCCTAAGCCCCAAAGTCCAGAAGTCTCTTCTGAGGTTGAGACTGACGCTTCTGGAGTTACAGCGCCACCCGCTAGGGCCGTGGCAAGAAAGAGTACTTGCAGGCCGCCGAATACGTTGCCTCCGCCGAGCAATATCGTTCCGTTCTTACCGACGCATACTGTTCCGCAGCCACAGTCTAAAGTTGTTTATTTCACACCAAAATCAGTCGTACCACCAAAACCATTCCGCCTGCACACTTGCAGTATCGAATGTGCCAAATTAGTTACACTACCTCTCAACGCTTTAAAAGGCTACAACCCCTTATCAAAACCGCTTCTGGTTGGCTGGCACCGTCAAATGTTCAAATACAAAGGCAAAAAGGGAATACGTTATCGCGCGCCGTGCGGCCGTTCGATCCGCAACATGATGGAGCTCCATTCATATTTACGCGTCACCCAAAGCGACATGAGCGTCGATAACTTTGATTTTGATTATTGGGTTCATTGTTTAGCTGAATTTGTTCTCGATAAAACGTTTAGAAGCAAGAGAGATATTTCTAATGGCATTGAAAATGTTCCGATACCATGCGTTAACTATGTAGACACAAGTCTGCCAGATTTTTGCAATTACAGCACAAAAAGAACTCCGTTAGCgggtgtaaatttaaatttggatgaAAATTTTTTAAGCGGGTGTGATTGTACTGATGATTGTTCCGATAAAACTAAATGTAGCTGTTGGCAATTAACAATTCGTGAAGCGCGAACACTCAATAAGCGAGTTCCCGAAGATCTTATAGGTTATAGTTACAAAAGATTACCAGATTGTGTCACAACAGGTATTTATGAATGTAACAGCCGATGTAAATGCGCTAAAACTTGTTTAAATCGAGTTGTTCAACACCCGCTTCAATTAAAATTACAGCTGTTCAAAACGGCTAATCGTGGCTGGGGAATTCGTTGTTTAAACGATTTACCTTTAGGgacatttatttgtatttacgcGGGAAATCTCTTAACAGACAAAATGGCGAATGAACGCGGCACAAATTACGGAGACGATTACCTCGCTGAATTAGACTACATAGAAGTTGTTGAACGCCAAAAAGACGGCTACGAATCAGACGTTACAGATATAGAAGATGAAAACGAAAACGACAACAATTCCGACAACGAAAACGATCCTAAAAATGATTCAAGCGACGCCTTGTTCGTTTCTCACGTGAAAGTAACAACAGGAACCAGCGTCCAAACACGTAGTCGCAATAAAATAACTGATGATTCCTCCGATGATTCATCAAATTCAAAACCAAGTGCAAGCCAAATTAGCACGAATTTAAACGATGATGAAACAGTAACAATTTCAGACGACGAAGAAATTGTAAGAGAAAAAACTTCGTTTCTTCCTAGCGATCAAACTGAAGAACAAATACctcaaagtaaatttaaaagtgtCAGGAAATTATTCGGCGAGGATGAAGTTTGCTACATAATGGATGCTAAAAACATCGGAAATATTGGGAGGTTTTTAAATCATTCTTGCACTCCAAATGTATTTGtgcaaaatgtttttgttgatACGCATGATGTGAGATTTCCCTGGGTTGCCTTTTTTGCAATGACGTATATCAGGGCCGGAACAGAATTAACTTGGAATTATAATTATGATGTTGGGTCGGTCCCTGGGAaagttattttttgtcattgtgGTAGCCCTGATTGCAGAGGAAgattattgtaa
Protein Sequence: MPRTVSTHHEEDDVIVLDNNEGSNSSNPTEVIDLDNYDVTGKKKKKRASWNNCINIECENGANLRAATIFCLNYYRVKIKPTKNQEVCEECYEKSVIYYEKLSQCLKNGDTLIEQELPQNDEFVEIDSDSDSEANIVDVCVDGVTACQISDDCFDFLAKELPSTMDSVLRKYDLEKQVNNAVAVLDEKEQRIEKGIDEMVALEKDLQQRVDKLRSTLYGEFQKKYEELPPVEFTLISPNKTMTTMTSPPRKDPERRSNRNIIKPASYCELMDDDVPSQDLTSDLEVTQEIGPQERFELAPPIIPEINLPPRGTFLRTRPQIGNSYYAQRQSVFGAWGKVHLLDIDNSSGKLLYKVKFEGKTKGLSSIKLVTGKQLAYSMPTEVRLDVGTRVIAVFTDESTIKKDSFYAGLIAEPLSQQNDWRYLVFFEDGYAQYVKHEKVLVICECSLKIWEDIHPDSQNFIKKYLETYPARPMVKIKTGQVMKTEWNGRWYFARVLRVDCSLVHMYFDADNRSEWIYRGSTRLGPLFLEFQAATARQEKAHHIPKLQQKQNSNSPQPYVEYPKPQSPEVSSEVETDASGVTAPPARAVARKSTCRPPNTLPPPSNIVPFLPTHTVPQPQSKVVYFTPKSVVPPKPFRLHTCSIECAKLVTLPLNALKGYNPLSKPLLVGWHRQMFKYKGKKGIRYRAPCGRSIRNMMELHSYLRVTQSDMSVDNFDFDYWVHCLAEFVLDKTFRSKRDISNGIENVPIPCVNYVDTSLPDFCNYSTKRTPLAGVNLNLDENFLSGCDCTDDCSDKTKCSCWQLTIREARTLNKRVPEDLIGYSYKRLPDCVTTGIYECNSRCKCAKTCLNRVVQHPLQLKLQLFKTANRGWGIRCLNDLPLGTFICIYAGNLLTDKMANERGTNYGDDYLAELDYIEVVERQKDGYESDVTDIEDENENDNNSDNENDPKNDSSDALFVSHVKVTTGTSVQTRSRNKITDDSSDDSSNSKPSASQISTNLNDDETVTISDDEEIVREKTSFLPSDQTEEQIPQSKFKSVRKLFGEDEVCYIMDAKNIGNIGRFLNHSCTPNVFVQNVFVDTHDVRFPWVAFFAMTYIRAGTELTWNYNYDVGSVPGKVIFCHCGSPDCRGRLL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00768301;
90% Identity: iTF_00768301;
80% Identity: -