Basic Information

Insect: Ophion ellenae
Gene Symbol: ken
Assembly: GCA_963210295.1
Location: OY723391.1:25965511-25974918[-]

Transcription Factor Domain

TF Family: BTB
Domain: zf-C2H2|ZBTB
PFAM: PF00651
TF Group: Zinc-Coordinating Group
Description: The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 2 2.8e-14 1.4e-11 45.3 0.0 9 97 30 114 24 118 0.93

2 2 9.6 4.9e+03 -1.4 0.2 23 44 432 453 425 464 0.78

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	2	2.8e-14	1.4e-11	45.3	0.0	9	97	30	114	24	118	0.93
2	2	9.6	4.9e+03	-1.4	0.2	23	44	432	453	425	464	0.78

Sequence Information

Coding Sequence: ATGTATACGGACGGTCTACTGACCCTCCATTATGGGAAACATCCGGCGACCCTGGCCGCGGAGGTCGGTTCGTGGTACCACGGCGATCGTCACGTCGACGTGATCCTCGCCTGTGACGATGGCGCGATCGCAAGGGCTCACCGTGTCGTATTGGCAACAGCTAGTCCACTTCTGGCTAGTCTACTTCGGAATCCGGCGCTGGATCACGTCGTCCATTTGTCCGGAGTTATGAGGACGCAACTCAATCATTTGCTCGAATTCCTTTACAACGGCCAGGCACTCATACCCTCGGGAGAGCTGACACCGTTGCGAGAGCTCTTCGACCTGTTACAAATAAAGTCGGAGCTGTTGGACCCGAGTCAGGCGCAGACCTCGAGCGATTCGGACGCCCTGAGGATAGCAACGCCACAGCCCTCGGACAGTCAGGAGAGTTCGAGCTACGAGTCTCAGTACGACAGCAGGCAATCGAACAATCCAGCCGATTGTTGTTCCGTGCTCATAAAGAGCGAGGGTTGCGACGAGGAGCCGGAAGTCGACGTCGAGGGCGTCGAGGGTGAGACGATGGTCGCCGACAACCGTGAAAGCAGTATCGAACCACCGAGGCGAAGGGATAGCTCCGATCCCGTCAATCTCAGCCTCAATTCTGGAATCTCGACTACCAGCGACAGCTCCCACGACACGACCCACAGGCCAGAGAAGACGATTCTCGAGAGGCGAGAGTCGATAGAGGAGGCGGAGGAGAGAAGACGACAATTAGCCGCCCGTCTATCGCTCGGTCTCGAGCCTGGCAAACGGAAACCAGAGGAGATACCGATCCCACCGGCCGAGGCGTACGTCGTAACGCCTCACAGGAAACGAAGACCGGGATTTCACAACGCGCCGGCACAAAATCCCGCCTTCGTGCCCTTCAACCCCGGATTCGAGACACCTAGAAGATTGCAAGCGCCACATCCGCTGAGCGTCTCGGCACCTCCTTACCTGCATGACAGATGCGTGACGCCACCGAGTGGATCGCACAGGCCGCCGAGTGCCGATCCAGCAACGGCGGCAGGTCTCGAGCCGCCTTGGGGAGCTTGGACGTTGCCGCCTTCGCGAGGACCGCCGCCAACGTCCACCGAGGATCCGCCCAAGTCGAATCCCGTCAGGGAGTATCGTTGCACCTATTGCGGCAAACAGTTCGGCATGTCGTGGAATCTCAAGACCCATTTGCGCGTTCACACGGGGGAGAAGCCTTTCGCTTGTCGCTTGTGCGTCGCGATGTTCAAGCAAAAGGCGCACCTGCTTAAGCATCTGTGCTCGGTGCATCGCAGCGTGATTGCCGCGCCGGACAACACATTTACCTGCTGCTTCTGCTCGCTGAGCTTCGACAGCTTGCAGGAGCTCATAAGACACTTGTCGGGGCCCCACAACAATTTGCTGTTGAGCAAAAATCTGCACGACTAG
Protein Sequence: MYTDGLLTLHYGKHPATLAAEVGSWYHGDRHVDVILACDDGAIARAHRVVLATASPLLASLLRNPALDHVVHLSGVMRTQLNHLLEFLYNGQALIPSGELTPLRELFDLLQIKSELLDPSQAQTSSDSDALRIATPQPSDSQESSSYESQYDSRQSNNPADCCSVLIKSEGCDEEPEVDVEGVEGETMVADNRESSIEPPRRRDSSDPVNLSLNSGISTTSDSSHDTTHRPEKTILERRESIEEAEERRRQLAARLSLGLEPGKRKPEEIPIPPAEAYVVTPHRKRRPGFHNAPAQNPAFVPFNPGFETPRRLQAPHPLSVSAPPYLHDRCVTPPSGSHRPPSADPATAAGLEPPWGAWTLPPSRGPPPTSTEDPPKSNPVREYRCTYCGKQFGMSWNLKTHLRVHTGEKPFACRLCVAMFKQKAHLLKHLCSVHRSVIAAPDNTFTCCFCSLSFDSLQELIRHLSGPHNNLLLSKNLHD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01477755;
90% Identity: iTF_00798893;
80% Identity: iTF_01101686;