Basic Information

Insect: Ophion ellenae
Gene Symbol: Hr39
Assembly: GCA_963210295.1
Location: OY723393.1:38508618-38522762[+]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 0.014 2.3e+02 1.8 2.5 127 172 17 59 14 79 0.56

2 5 0.045 7.3e+02 0.1 4.5 45 165 221 340 188 363 0.70

3 5 2 3.3e+04 -10.2 15.9 78 143 385 453 347 494 0.44

4 5 3.8e-08 0.00062 20.1 0.0 1 21 558 578 558 582 0.92

5 5 1.4e-73 2.3e-69 235.6 0.0 97 408 620 931 586 931 0.81

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	0.014	2.3e+02	1.8	2.5	127	172	17	59	14	79	0.56
2	5	0.045	7.3e+02	0.1	4.5	45	165	221	340	188	363	0.70
3	5	2	3.3e+04	-10.2	15.9	78	143	385	453	347	494	0.44
4	5	3.8e-08	0.00062	20.1	0.0	1	21	558	578	558	582	0.92
5	5	1.4e-73	2.3e-69	235.6	0.0	97	408	620	931	586	931	0.81

Sequence Information

Coding Sequence: ATGTCGGATCAAAGCGGGCCCGGGGAGGGCCCGGGCTGGTGGCAACCACCGCAATCGTGGAAAACGACCACCAACGTCGTCACATCCGCCGCAGCTACCTCGtcttcctcgtcgtcgtcgtcctccaCGATTTCCTCGTCGCGCATCCACGAGGCcggaaaaaatgtttccgtTACGACAATCAACGTGCCAACGGCTCAGGAGATGCACGACGGTAAAAGCGTGTGCAAGTACCTGGGAGGTCAGAACGGCGTGACCGTATCGGTGGTCTCGAATTGCGGTAGCGGCGGAGGAAGCGTAATGGGGGCTGGACCGGGTGGTGGAGGAGGTGGCGCCGGTGCGTCTTCCTCTTGTCCGGAAGCGAGTTGCCTCGAGGACCTCGAGGACAGCGACGGTGAAGTGAGCAAGATCGACTTTCGGGGTGTGAATCTACGAACGAAGAAGAAGCGCGACGGTGCAACGACATCGGTTGGCTCGGAGACGGATTGCTGCGGTGCCGTTGGAGGTGACAATCTCGAGCAACAACAGCCCGAGAGACCGATGTCATGGGAGGGCGAGTTGTCCGATCAGGAAATGTCTTCCAACACGATAACGAACCAGGATCACGAGGAGACGTCTATGGAGGGTGTCCAGGTGTGCGGTGCGAGTCCGGGGCCCCAGGAGCAAAAGTTCCCGATAAAGCCGGAGCCCGATTTCCGGTCGAGTCCGAGTCTGCTGATAGGCTCCCACAACGAGGGCAGCCTCGGGCTCTCGCACGTCCAACAgttgcagcagcagcaacagcagcgaGGCATCGAGGGCCTCGAGGCCCAGCAGCAGAGCGACCTGCCGCTACTCGTGGGCAAACTCCTCGGCGGTTACAACAGCTCGACACCGAATCACAGCCCCATACTGAATCCCCGTCATCATTTGACGAAACACAGCCACACGAGGTCCCAGGTGCCTTCGCCGGATTCAGCTATACACTCGGCCTACAGCGTATTCAGCTCGCCCACCCAGAGCCCACACGCCGCACGTCATTCGGCACTGGGCCCCGGAAGCCCCGTACCCTCCTCCAGCCTCTCACTTTCGCGCCACAGCTTCAACAACTCGACCTCGTCGCTCTCACTGTCACTGTCACACTCACTCTCGCGCAACAATTCCGACGCATCCAGCAGCTGTTACAGCTACGGCTCACTGAGCCCGCCCACGCATTCCCCGGTGCAGCAGCCGCGCCACGCccagcatcatcatcatcatcagcagcagcagcagcagcaacagcagcatcaTCATCAAGCCCAGCAGCAATTGCCCGCGGCCGGCAGCCCCCTCCATCTAGCCACGAATCCTCACGTCTACGCCAGCCAGGAAATCCCAACGGAGAGCCATCCGGAGGATCAGGAAGACTGCAAAATCCCAACCGCCGCAGCTGCTGCATCGAACAGCGGCATTTCGACGAGGCAGCAATTGATCAACAGTCCCTGCCCGATATGCGGCGACAAGATAAGCGGCTTTCACTACGGGATATTCTCGTGCGAATCGTGCAAAGGCTTCTTCAAACGGACCGTGCAGAATCGCAAGAATTACGTGTGCCTCAGAGGCGCCGGATGCCCCGTGACCGTTGCCACGCGCAAGAAATGCCCCGCTTGCCGATTCGACAAGTGCCTCAACATGGGCATGAAACTCGAGGCTATCAGGGAGGACCGAACGCGCGGTGGAAGAAGCACGTATCAGTGCACGTACACGCTGCCGGCGAATCTCATCGGTGGCGCTGGCAGTGGCGCTATGAACGCTGACAAAATGTCCGGTGGCAATTGCAGCCCGGCACCGCCAGGCGCCGAGCATCATCATTCCGCCAGGCATCATTGGAATCACTCACACAAGATCCAAGTCGTGCCACAATTGCTACAGGACATCATGGACGTCGAGCATCTTTGGCACTACAATGACAATGATCGGGTCACCGGCAGCGCCACCGCTGGCCTACCAACCAACAACGGATCAACCCTCTCCAATGAACTGTCCGGATGCCTCGGCACTACCGGCTCGACATCCTGCGCCACGAGTGCAACGGGAAACAACGGCAATGCCGAGGCTAGGCCACACGACAATAACGTCACCAATTCGAATCCCAATGAGCATCGGCAATCCAACGCGAGCTTGAACGAACAGAGCAATTGCACCGGCGCGACCGCCAATGGCAATAACACCACGCAGAATCCTGACTTTCTCTCGAATTTGTGCAACATCGCGGATCATCGGCTGTACAAAATTGTCAAGTGGTGCAAGAGCTTGCCGCTGTTCAAAAATATCTCGATTGACGATCAGATATGCCTGCTCATCAATTCGTGGTGCGAATTGTTGCTATTCTCGTGCTGCTTTCGCAGCATGAGCACACCCGGCGAGATCAGAGTCTCGCTCGGCAAATCAATCACGCTCGAGCAAGCGAGACAACTCGGCCTGGCCACATGCATCGAGAGGATGCTCGCATTCACGAATAATCTCAGGCGACTCAGGGTCGATCAGTACGAGTACGTCGCGATGAAGGTCATCGTTCTCCTGACTTCGGACACGAGCGAGCTCAAGGAACCCGAAAAAGTCAGAGCATCCCAGGAGAAAGCTCTTCAGGCCCTACAGCAATACACGATTGCGAGGTATCCCGAGATGCCGGCTAAATTCGGCGAGCTTTTGCTTCGAATACCGGATCTTCAGAGAACTTGTCAGGCCGGTAAAGAGCTGCTCAGTGCGAAACGGGCCGAGGGGGAGGGCAGCTCGTTCAATCTACTCATGGAATTGCTGAGAGGAGATCATTGA
Protein Sequence: MSDQSGPGEGPGWWQPPQSWKTTTNVVTSAAATSSSSSSSSSTISSSRIHEAGKNVSVTTINVPTAQEMHDGKSVCKYLGGQNGVTVSVVSNCGSGGGSVMGAGPGGGGGGAGASSSCPEASCLEDLEDSDGEVSKIDFRGVNLRTKKKRDGATTSVGSETDCCGAVGGDNLEQQQPERPMSWEGELSDQEMSSNTITNQDHEETSMEGVQVCGASPGPQEQKFPIKPEPDFRSSPSLLIGSHNEGSLGLSHVQQLQQQQQQRGIEGLEAQQQSDLPLLVGKLLGGYNSSTPNHSPILNPRHHLTKHSHTRSQVPSPDSAIHSAYSVFSSPTQSPHAARHSALGPGSPVPSSSLSLSRHSFNNSTSSLSLSLSHSLSRNNSDASSSCYSYGSLSPPTHSPVQQPRHAQHHHHHQQQQQQQQQHHHQAQQQLPAAGSPLHLATNPHVYASQEIPTESHPEDQEDCKIPTAAAAASNSGISTRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCLRGAGCPVTVATRKKCPACRFDKCLNMGMKLEAIREDRTRGGRSTYQCTYTLPANLIGGAGSGAMNADKMSGGNCSPAPPGAEHHHSARHHWNHSHKIQVVPQLLQDIMDVEHLWHYNDNDRVTGSATAGLPTNNGSTLSNELSGCLGTTGSTSCATSATGNNGNAEARPHDNNVTNSNPNEHRQSNASLNEQSNCTGATANGNNTTQNPDFLSNLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSMSTPGEIRVSLGKSITLEQARQLGLATCIERMLAFTNNLRRLRVDQYEYVAMKVIVLLTSDTSELKEPEKVRASQEKALQALQQYTIARYPEMPAKFGELLLRIPDLQRTCQAGKELLSAKRAEGEGSSFNLLMELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00059522;
90% Identity: iTF_01102090;
80% Identity: iTF_01101436;