Basic Information

Insect: Ophion ellenae
Gene Symbol: FTZ-F1
Assembly: GCA_963210295.1
Location: OY723395.1:18070990-18083403[+]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 3.9e-87 6.4e-83 280.3 4.8 7 408 1 423 1 424 0.76

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	3.9e-87	6.4e-83	280.3	4.8	7	408	1	423	1	424	0.76

Sequence Information

Coding Sequence: ATGCGAGGCGGTAGGAACAAGTTTGGCCCGATGTACAAGCGGGACAGAGCGAGAAAATTGCAGCTACTGAGACAACGACAATTGGCGATTCAAACGATAAGGGGAAGTCTGGGCGATCCGTCGAGTTATTCGTCCTCGGTGACGCCCTTCCTCCACATAAAGCAGGAGATTCAGATACCCCAGGTGTCGAGTCTGACCTCGTCGCCGGACTCGAGTCCGTCGCCAGCGGCGGTGGCCGCGGGTCTCGTGACGAATCAAGCGGGCGGCGGTGCCAGCGGCGGGGGCGGCGTCAGTGGCGGCGGTGGCGGTGgaagcggcggcggcggcggcgggagCGGCAACGGCGGTGGCGCCGGCCAGCATCAATTGATCGCCCCCTCGTCCCAGACCGCGATAACGGGCGGCAATCATCTCTACAATCCGAATCCAAGCTTGGACGGGAAATTGTGGGCCGCCAATTCGACTACCTCAAGCCCAAAGGCTTTCAACTTTGGCGAACACTCGAGTCAGGGCGGCCAAACTAGCGCCACCGTCAATCCCAATCAAGTGCCGAACACCGGCACATTGAAAACTAGTCCGATGATAAGAGACTTTGTCCAGACGGTGGACGATCGCGAGTGGCAAGCCTCCCTGTTCAGTTTATTACAGAATCAAACGTACAATCAGTGCGAGGTTGACTTGTTCGAACTAATGTGCAAAGTGCTCGATCAGAATCTCTTCTCCCAGGTCGATTGGGCGAGGAACTCCGTTTTCTTCAAGGATCTCAAGGTTGACGACCAAATGAAGCTACTGCAGCACTCCTGGTCGGATATGTTGGTGCTCGACCATCTCCATCAGAGGTTACACAACAACTTACCGGACGAGACGACACTTCACAACGGCCAAAAGTTTGATCTCCTCTGTCTCGGCCTACTCGGTGTACCTTCGCTCGCCGATCTCTTCAACGATCTTTCCTCAAAACTACAAGAGCTGAAATTCGATCTGTCCGATTACATATGCATAAAGTTTCTAATGCTCCTCAATCACGATGTACGTGGTCTAGTGAACAAGAAGCACGTTCAGGAGGGTCACGAGCAAGTACAACAGGCGCTTCTGGATTACACGCTGAACTGTTATCCATCAATACCGGATAAGTTCAACAAGCTGTTAGCAGTATTACCGGAGATTCACGTGGTCGCGAGTAGAGGCGAGGATCACCTTTATCAGAAGCATTGCAACGGCGGTGCGCCGACTCAGACACTTCTCATGGAGATGTTACACGCCAAGAGAAAATga
Protein Sequence: MRGGRNKFGPMYKRDRARKLQLLRQRQLAIQTIRGSLGDPSSYSSSVTPFLHIKQEIQIPQVSSLTSSPDSSPSPAAVAAGLVTNQAGGGASGGGGVSGGGGGGSGGGGGGSGNGGGAGQHQLIAPSSQTAITGGNHLYNPNPSLDGKLWAANSTTSSPKAFNFGEHSSQGGQTSATVNPNQVPNTGTLKTSPMIRDFVQTVDDREWQASLFSLLQNQTYNQCEVDLFELMCKVLDQNLFSQVDWARNSVFFKDLKVDDQMKLLQHSWSDMLVLDHLHQRLHNNLPDETTLHNGQKFDLLCLGLLGVPSLADLFNDLSSKLQELKFDLSDYICIKFLMLLNHDVRGLVNKKHVQEGHEQVQQALLDYTLNCYPSIPDKFNKLLAVLPEIHVVASRGEDHLYQKHCNGGAPTQTLLMEMLHAKRK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00263585;
90% Identity: iTF_01056028;
80% Identity: iTF_01101439;