Basic Information

Gene Symbol
-
Assembly
GCA_001266575.1
Location
JTDY01000198.1:148297-158730[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 24 0.0033 0.21 12.0 1.5 3 23 675 696 674 696 0.96
2 24 3.5 2.2e+02 2.5 1.1 4 23 1079 1100 1077 1100 0.84
3 24 0.055 3.5 8.2 0.6 1 21 1105 1125 1105 1126 0.96
4 24 5.9 3.7e+02 1.8 0.4 1 23 1166 1189 1166 1189 0.90
5 24 0.00021 0.013 15.8 0.9 3 21 1200 1218 1200 1219 0.96
6 24 0.26 16 6.1 0.5 2 23 1227 1249 1226 1249 0.93
7 24 0.073 4.7 7.8 0.7 3 23 1268 1289 1266 1289 0.92
8 24 0.0014 0.091 13.2 2.1 1 23 1294 1317 1294 1317 0.93
9 24 0.1 6.6 7.3 0.0 1 23 1343 1366 1343 1366 0.90
10 24 0.016 0.99 9.9 3.4 1 23 1371 1393 1371 1393 0.97
11 24 0.0074 0.47 10.9 0.2 1 23 1399 1422 1399 1422 0.95
12 24 0.0067 0.43 11.1 0.9 1 23 1436 1458 1436 1458 0.97
13 24 0.00015 0.0094 16.3 1.8 1 23 1510 1533 1510 1533 0.97
14 24 0.0029 0.19 12.2 0.9 1 23 1593 1616 1593 1616 0.95
15 24 0.0017 0.11 13.0 1.5 2 23 1645 1667 1644 1667 0.95
16 24 0.073 4.6 7.8 0.1 2 23 1673 1695 1672 1695 0.93
17 24 0.0055 0.35 11.4 0.3 1 21 1739 1759 1739 1760 0.95
18 24 0.001 0.065 13.6 0.6 1 23 1770 1792 1770 1792 0.93
19 24 9e-05 0.0057 17.0 0.4 2 23 1882 1904 1881 1904 0.93
20 24 2.8e-07 1.8e-05 24.9 1.4 3 23 1911 1931 1910 1931 0.98
21 24 0.00093 0.059 13.8 0.4 1 23 1951 1973 1951 1974 0.95
22 24 0.29 18 5.9 0.0 1 23 1995 2017 1995 2017 0.97
23 24 0.011 0.71 10.4 0.6 1 23 2023 2046 2023 2046 0.96
24 24 0.00031 0.019 15.3 0.4 1 23 2054 2077 2054 2077 0.96

Sequence Information

Coding Sequence
ATGACTGTGAACTATGATCGTGTTTGTAGACTGTGCTTGTCATCTCGAGGCGAATTACTGCCGATTTTCCCTACCACCAGTTCGGATGACTTGGAACCTCCCATCCTCGCTTCAAAAATAAAGGATTGTGTGTCTGTACAGATAAACGAAGATGACGACCTGCCGACGAATGTCTGCAGGAAATGCGTGGACAATGTCAACAACTGGCATTTATTCAAGACTGTATGTGCAAAGACACAAAACAAACTACTGTCTCTCATAAGAAAGGATGGAAGCCTACTAGAAGAGGTGCATATCAAAAGTGAACCCTATTCTGATGAGGCTTATGATGATGGAGTGGTTATTGACAGCTCATATCCTGAAGCTGAGAATGCGGGCTCTTCGAGTAAACTACAGCCTGAAGGGCCCCCAATCCTGGCCTCATTGGGACTCACCCCTCGGAGCGACAAGAAATGTGTGGATCCACGAATGGATTGGCACCGAGTCCATGCAATATTGGATATGGTTCAAGAAAGCAATGTGATTGATTCACTCCAATCCGTAGAAGAGAGTGATGTTTTGCATCACTCCGATCATGAGTCAGACACAGAGACGGAACTCCAACCAGATCTAGATGATACTTTCATTGATTGTAAAAATGGCTATGCTTGTAGAAACAAAAAGATCTTATTCAAAAATCCTCAAAGAGTCGGCTCGGGGCCTAAAGATATAAAACTGAAGAAACGGAAAGTCAATGTCTACAAACATTGTGGAAAACCCAAAAGTGCTTGGCAGCTATTATTTACGGATGATCTACTCGATCTGATTGTTTCATCAACAAACGAAAACATACTCCGACATGGCAAGGGATTCAAATGTTCCACCAATGTTAGTGAAGTCAAGACTCTAATTGGAATCTTGTATTTGAACGGAATAATGAGGGCAACTCATCAGAAATGCAGTGACCTCTGGGACAAAGACTGCGGCGTCCCGTCCGTTATGAATGCAATGACAAACAAACGTTTCAACTTTCTTTTACAAAACATCTGTTTCTATAGCCAAGAGGATGACGATAGCATAATGCAGTTCGATACTATGAAACGAATTCGCAAAGTGTTCGAAATCTTCGCCATGAACTGCAGAACAACCTTCGACGTCGAGAGTACCGCCGTCGTTGATGAGATCATTGTGCCAGTTTATGGTCCTTGCCCGTTTCGATACGACATTGATAAGAAACCACTGAAACAGGGAGTTAAAATGGTATTGCTTGTTGATCCTAATAACTTCTATGTGAGCAATTTGGACGTGATAACCGATCCGTATTTTGGAGCTGACGAGATTGTGAAAAAAATTACTCAACATTTGTATGGCACTGGGAAAACGATCATAATGGATAGCTGGTACTTTTCCTCCAAGTTGATGGATACCCTGAAGAATTATCAGCTCTATACGATTGCGACACTCCACCCAAAGAGCGATGACATACCTCCATTGTTTCTATCGCAGTACAGAAAAAGCTGTACATACATATCTGGATTCGTAGACGCTGAAGTCTCGCTAACGTCTCACGTGAACTCACAGTCGAAAGCGACCAATGTTGTATCAAACGAGCCGCGGTTTTATCGAAAAGGTCACACGAACCGTACAACATCGGTATCAGCATATAAAAAGAATCAATCAGCAGTTGAAGTTCTGGATGTCCTGATGCATTATTATACAACATTGCAAAATACGAACGATTGGACACTTTCATTGTTCTTTACATTGCTCAATATTGCGTCTGTTAATGCTCAAGTTATATGGAGCTCACGAAACACTATAGTCGTTCCACGGCGTTCATTTATCAGAGATTTGGGGTTGGGCCTGATGGAGGATGAGGGGCTGGAGAGTGAGAAAGATGAGGAAGATGAATACGAAGACGAGGTAAAAGCCCCTCAGCCGGTAAAAGTCCCGAACATGCCTGAAGTCTCCATCACCGTAATGCGGCCCACCGGCGAGACGCTGCAATCCCGCCAAGGTATACAACAGATAGCCTCCAAGGACTGCCTTATTTGCGGCCGCTCGTACAGATACTCACACAACGCGAGGCGTCACGAGCTCACATCACACAAATTCGACCGCTACaccaacaaaataaacagtaaaaaaTCATACTCTCGCATGCAACCTAAACTCAGACCTAACCCTTTCAACCCAAAATCGCGACTCATGCCCAATCCCATCAGCCATAAAATGCAATTACTACCCAAAATTATGCCGAGATTGATGCCGCATCTCAACTCTCAAATCAACAAGAAAATTATAACTCCACCGAAACCGATACCCATTAAATCTTCAAAGACACAACAGAACAACTTGCCGTATCCGTTGCGCATCAAAGCGCTCAAAGATTTGCAAATAAAGAAAAAGGAACCGCAGATTTTGAAAAGACTACTCACATCGAAACCTGAGGTCCTGGTACCGGAACCAGATATTATGAACTCTGGCCCAGAAAGCCCTGAAACTCTAATATCTGAGCCTGAAATAGCGTCTTTCCAAGTTGAGGCGATTCTTTCGGAGCCTAACGATTACGATGAACATCAAGAAGAGGAACCAGAATCAGAAGTGCATAACAGTCAGAGCCAAAATTACGACACCGTCGACATGGACTCTGAAAATGAAATAGAAATTGCACGACAGCAGGAAAGCGTTGATGAGAACGTTCATGAGACTGAAGAAACTCATGATGAAGATGACAATATTCAGCATGCTGACGAAAATAACTTTGTAGAAACTGACAAAGTGGGAGAAAATGGAAGTGAGAAAGATCTCAGTCCTCAAGAAGCAGCACTCGGTGAGGAGAGTAATGGGAATATGGATGTAGATGAAAATTACGAAGCCAAAGATGATGAACGTAataatgaagaagaagaagaaggaaatGAGGAAGGCGAACGAAATGAGGAAGGTGAAAATGAAGACCTACAGGCCAGTCTAGGGACTGAAGAAAACGAGGATGAGGAAGACCATCCGCCCACCGCACTGGCGCCGGATGTAGAGTTGAACGAAGATATGCACCATAACTCCAACACTTTCAATAGCGAGATGAACGACGACGAAGAAGAACCGGACGAAAGCGCCGATATCAATGATACTGTCGATGGTGAAACCACTGCCAACATACTCGATCCTGATAAAACGTATGTCACCAACTCTCAGAAAGACTTCATCAAAAGATATCGTGATATTATCCTACAGATCAATACGAAGAGATGTCTCTGTTGCGATAAGGAATATCCACGCAGAAAAGCTGTCATACAACATCTACAGAAAAATGGACACAAAGTTCCAAAACATACCTGCTACAATTGCGTCGTTACTTTTACCCATATTGGCGCTTTACTCAGCCACATGAGACAAAACTCTTGCACCGATCTGTGGAAGATAATCTACGACGAGAATGGTATCACGAGCGACATGATCATTGAGGAACCTAAGAGCAAAATCCAAGCCAAAGATATTTTCAATGCGAAATCTTATGCTTGTAGATTGTGCCCTGCAAAATTCCAGCTAAAGCAATCTATCATGAAGCATGTTTCTGAGTTCCACGAAGATGGCCAGTCTGCAGTTCCTCTCGGCTGCGTACATTGCGGAGCTTCCTTCAAAGATAAAACGTTACTCAAGAAACATATCCGCAACGGCGATTGTACTGTTTATATCCATTGTGATCTATGCTCTGAACAATTCACCAACATGCAAGAGTTCAATGATCATGCACTGTCCGCCCACACTGAGCACTTTGTCAAAACTGAAAATCAGAGCGTCGATGGACGACTCACAGACTGCTATCTTTGTGGGATGAAGACTAGCAGCTATACAAATCTGCTCAAACATTTCAAAGCAGTGCATGATGAAATACCGCATCACTGCCAGTTTTGTGGTGTCAAATTTGAGCAACCGGTAGATCTTAACAAGCACATGTACCTGGAACATCCTGGTCAAACTCCAGACATGCAAACCAATCAACCAGACATGTCTCTCGTCAAAGAAGAAGCCGAGGAGTACCACTACTCTTGCACGGAGTGCAATGCAATATTTGAAACTGTAGATGCATGGACTGATCACCAAGTAGCTGAACATAACCAAGTGGCACATCACTGCGACCAGTGTGAGAAGAAATTCTTGAGGCCCTCTGAGCTAGCAGAGCACAAGAACACTCACTTGAGAGTAAAATTCTATCCTTGCAGCATATGCTCTAATTCGTACAGCACCCCGCAAAAGTTGTCGGACCATGTCCAAAACGTTCATCCTGGTGCCGGTGGATCTCAGGTCAATCCAGACAATGAATTTTTCTGCGATATCTGTATTCGAGGTTTCAAAAGTCGTCAGGCTTACTCGAATCATATGCGCATTCATGCAAAAGTGCCGACCACCAATAGAAAGCCTGGTGAACCTAAGGGATTCGACCCGCGCATCATTGGGAAACCGATCAAACAGTTCACTATGTCCAATGTGATTCAACCTGGTTTCATTAACTTTAAGCCAAATGCAAATGTTCCTAATGCTCCTTATTCGTGTGATATTTGCGGCAAAGGCTTCATGCATAAGAAAAATATTTGGAAACATAAAAAAGTGTTGCATGCCGATATAATAAACGACAGAAACGACAGTGAAGAGAACACGATGCACGCCTCGACCGAGGAAGACGAATATAATGTCGATGAAAATGGCGTATTACTTTCAACACCACAGTTtaacagttttaattttaccaattTCTCTAATAATGTGGTGCTGCCTCAGGCAGATCCTATGCCTTTCGCTTGCGAATTATGTTCCAAGCGATTCCCGCTTAGGACTAGTCTGTGGAAGCACAAACGCGCTAAGCATGGAATCACTAATGCAAATCCCAGCGGCAGTGGCGACGCGCATACACAAGCAGCGCCTAGTGAAAGCCAAGGTGGTGGTCGATCTAGCTGTACCATTTGCAAAATTACATTCGCAGACAAAAAATCTTACTATCGTCACAGAAAAAACGTTCACAAATCAGCGACGCAAATGTGTAAGATATGTGGCAAACCACTGAATTCCACTCTGGAACTGTACGAACATCTGAAAGCAGCTCACGCTAGAGAGTTGCTTGGGTACAATGCCAATCAAAATACGAGTAAAGCTCAGGATGAATCACAAGATATGGATGGCGATTTTGACAACGAGCAAGATGCTGTAGATCCTAGCGTTGACTATCAAGCACGGTATCCGTGTGATACTTGTGGCAAGCAGTTTGTAGGACTACTCTCCTTGCAAAATCATCAGTGTATAAATCAAGTACCTTCACAACCCCAGACTTTTGACTGTGAAATCTGCCACAAAAGTTACACTTCCATCGCCGCATTGAAAAGTCATCGCGGTTGGCATCTTCGATCGCCCGATGGCAAGGCGGCCGCTAATAATAGTGGTCTATGGATGCCTCAGCACAAGGTCACCAGCAAGGTGAGCAAACACGAAGTCGTAGAACCTGCCACAACGCCAGTGGTGACCCGACTCCACCAATCCACTCCTGCAGCCGTGGCCAAAAGGAGATTACCCCCCGAAGTAGAAGTGACCGTCGTGAACCCGAACAAAAAGATGCGCTCGGACGATTCCGTCGAGACGGACCAGCAAGGCGAAGCTGTCGAAGGGAAGTACTGTACAATATGCGACAAGGAGTTCACGAAACGAGCGGCGTATCAACGCCACATGGATGAGGTCCATCAGCCGAATTCTGTCTTTTGTCCAGTCTGCGATAAGAGTTTCACACGGAAATCGACTCTGCTTGTGCACATGAAAAAGCACTACGAAGGTGGCGGAGAGGGTAGTTCTTCGACAGTTCAAGCGGATGAAGATGAGGGCTTCTCGTGTGAAGTATGCGGTGCGCAGTTCGACACAGAAAATGGTTTGAGGGCGCATCGTATCAGACATCACGGGGAGGAATCGGGTGATTCGGAGGATGATGGTCAAGTGCCCATCGCACAGCCCGGGGAGTTCACATGTGGCCAGTGTGGAGACGGCGTTGCTACCGCTCGCGATCTGATCACGCATCGCGCCATACATTCAACACCTACTAAATTCTACTGTAACATCTGCAAAGTGTACTTCGTGAGGGCACTAGACTTGTCCTCACACACGCGCGCGCGGCACGCTGACAATGAGAAGGTGTTCTTCCCATGTGCCATGTGTGACCGCTTCTATATGAACAAGAAGAGTTTACAACGTCACATCGACATGGCTCACTGA
Protein Sequence
MTVNYDRVCRLCLSSRGELLPIFPTTSSDDLEPPILASKIKDCVSVQINEDDDLPTNVCRKCVDNVNNWHLFKTVCAKTQNKLLSLIRKDGSLLEEVHIKSEPYSDEAYDDGVVIDSSYPEAENAGSSSKLQPEGPPILASLGLTPRSDKKCVDPRMDWHRVHAILDMVQESNVIDSLQSVEESDVLHHSDHESDTETELQPDLDDTFIDCKNGYACRNKKILFKNPQRVGSGPKDIKLKKRKVNVYKHCGKPKSAWQLLFTDDLLDLIVSSTNENILRHGKGFKCSTNVSEVKTLIGILYLNGIMRATHQKCSDLWDKDCGVPSVMNAMTNKRFNFLLQNICFYSQEDDDSIMQFDTMKRIRKVFEIFAMNCRTTFDVESTAVVDEIIVPVYGPCPFRYDIDKKPLKQGVKMVLLVDPNNFYVSNLDVITDPYFGADEIVKKITQHLYGTGKTIIMDSWYFSSKLMDTLKNYQLYTIATLHPKSDDIPPLFLSQYRKSCTYISGFVDAEVSLTSHVNSQSKATNVVSNEPRFYRKGHTNRTTSVSAYKKNQSAVEVLDVLMHYYTTLQNTNDWTLSLFFTLLNIASVNAQVIWSSRNTIVVPRRSFIRDLGLGLMEDEGLESEKDEEDEYEDEVKAPQPVKVPNMPEVSITVMRPTGETLQSRQGIQQIASKDCLICGRSYRYSHNARRHELTSHKFDRYTNKINSKKSYSRMQPKLRPNPFNPKSRLMPNPISHKMQLLPKIMPRLMPHLNSQINKKIITPPKPIPIKSSKTQQNNLPYPLRIKALKDLQIKKKEPQILKRLLTSKPEVLVPEPDIMNSGPESPETLISEPEIASFQVEAILSEPNDYDEHQEEEPESEVHNSQSQNYDTVDMDSENEIEIARQQESVDENVHETEETHDEDDNIQHADENNFVETDKVGENGSEKDLSPQEAALGEESNGNMDVDENYEAKDDERNNEEEEEGNEEGERNEEGENEDLQASLGTEENEDEEDHPPTALAPDVELNEDMHHNSNTFNSEMNDDEEEPDESADINDTVDGETTANILDPDKTYVTNSQKDFIKRYRDIILQINTKRCLCCDKEYPRRKAVIQHLQKNGHKVPKHTCYNCVVTFTHIGALLSHMRQNSCTDLWKIIYDENGITSDMIIEEPKSKIQAKDIFNAKSYACRLCPAKFQLKQSIMKHVSEFHEDGQSAVPLGCVHCGASFKDKTLLKKHIRNGDCTVYIHCDLCSEQFTNMQEFNDHALSAHTEHFVKTENQSVDGRLTDCYLCGMKTSSYTNLLKHFKAVHDEIPHHCQFCGVKFEQPVDLNKHMYLEHPGQTPDMQTNQPDMSLVKEEAEEYHYSCTECNAIFETVDAWTDHQVAEHNQVAHHCDQCEKKFLRPSELAEHKNTHLRVKFYPCSICSNSYSTPQKLSDHVQNVHPGAGGSQVNPDNEFFCDICIRGFKSRQAYSNHMRIHAKVPTTNRKPGEPKGFDPRIIGKPIKQFTMSNVIQPGFINFKPNANVPNAPYSCDICGKGFMHKKNIWKHKKVLHADIINDRNDSEENTMHASTEEDEYNVDENGVLLSTPQFNSFNFTNFSNNVVLPQADPMPFACELCSKRFPLRTSLWKHKRAKHGITNANPSGSGDAHTQAAPSESQGGGRSSCTICKITFADKKSYYRHRKNVHKSATQMCKICGKPLNSTLELYEHLKAAHARELLGYNANQNTSKAQDESQDMDGDFDNEQDAVDPSVDYQARYPCDTCGKQFVGLLSLQNHQCINQVPSQPQTFDCEICHKSYTSIAALKSHRGWHLRSPDGKAAANNSGLWMPQHKVTSKVSKHEVVEPATTPVVTRLHQSTPAAVAKRRLPPEVEVTVVNPNKKMRSDDSVETDQQGEAVEGKYCTICDKEFTKRAAYQRHMDEVHQPNSVFCPVCDKSFTRKSTLLVHMKKHYEGGGEGSSSTVQADEDEGFSCEVCGAQFDTENGLRAHRIRHHGEESGDSEDDGQVPIAQPGEFTCGQCGDGVATARDLITHRAIHSTPTKFYCNICKVYFVRALDLSSHTRARHADNEKVFFPCAMCDRFYMNKKSLQRHIDMAH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00663313;
90% Identity
iTF_00663313;
80% Identity
-