Basic Information

Insect: Onthophagus taurus
Gene Symbol: TRERF1
Assembly: GCA_000648695.2
Location: NW:109965-211510[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 4e-05 0.003 17.5 0.2 2 23 183 204 182 204 0.97

2 6 6.4e-08 4.9e-06 26.3 1.3 1 23 210 232 210 232 0.98

3 6 6.1e-05 0.0046 17.0 2.6 1 23 238 262 238 263 0.95

4 6 0.00033 0.025 14.7 0.8 2 23 432 453 431 453 0.97

5 6 0.00046 0.035 14.2 0.0 1 23 1320 1344 1320 1344 0.97

6 6 5.9e-05 0.0045 17.0 0.8 1 23 1381 1403 1381 1403 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	4e-05	0.003	17.5	0.2	2	23	183	204	182	204	0.97
2	6	6.4e-08	4.9e-06	26.3	1.3	1	23	210	232	210	232	0.98
3	6	6.1e-05	0.0046	17.0	2.6	1	23	238	262	238	263	0.95
4	6	0.00033	0.025	14.7	0.8	2	23	432	453	431	453	0.97
5	6	0.00046	0.035	14.2	0.0	1	23	1320	1344	1320	1344	0.97
6	6	5.9e-05	0.0045	17.0	0.8	1	23	1381	1403	1381	1403	0.98

Sequence Information

Coding Sequence: ATGACAGCAGTGAATGCGGGTGTCCACGAAATTACAGGTGTTCGCCTACCCCTCCAACACTATACCGGAAGCCATGCTGTGTTCATGTACAGTACAGCCAGTGACGGCAACGTCACCCTTCAATTGAAAGAACCTGATGACTTGGATAGGACAAGTCTTGCGGCCGTTCTTGCCAGGCTGCAAGATGACtcatctttttcaatttcttatcAAGATGCCGATATGTTGTCCGATGGTAGCATCGATGTCTTGCTCGGAACCGGTCCTGGTAGTCAACAAGgTGGGGGTGAGTCAGTTACGACGGCACCCTTTGACCTCTTCGACTCGTCCAACGGGCCCGACCTGACGTTGTCCCCGCAGACGTTCACCAACTCCACCGAGGCTTTCATCAACGACAACTCCAACAGTCTGGGAGTCCCTGCGGACAACGAAGCAGTTTCTTCTACGGACGAGAAAAAGCCGTCAAGTCTCAACTCGGAAGCGTCCAAGTTAACGGTAAAAAGACCGCGACCGAAAGCAGTATCACCAAATCGACAAGGACCTCAACAATGTCAGGTGTGCTCAAAAGTCTTCGGTAACGCGTCAGCCCTCGCCAAGCACAAGCTTACACACAGCGACGAACGGAAATACATCTGCAACATGTGCGGAAAAGCGTTCAAGCGGCAGGATCACCTGAATGGTCACATGCTCACCCATAGGAACAAAAAACCGTACGAGTGTAAAGCGGAGGGATGCGGAAAAAGTTATTGCGATGCGCGGTCATTGAGAAGACACACTGAAAATCATCATAGCAGTGGGTCTTCTAATGGAGCCACCACAATGTCTCCAGCTCAAGGAGCAGCTTCCGGTGATGCAGCTTCGCCTCATGGGTCAAGCTGTATTCAATATGCACCTCCACCAACGACATCGGTTACATCAACAACCACCACTACGACTACTTCTTTAGGAAATAGTGGATCAAGTAATTCGACAGGAAAAAGTCAGTTACAACAACTTTTAGCAACAGAACCTGTTAAGGGAGGTGGTGCCAACGACGGCCTAACGAAGCAGCTGGACCTGATCCATCAAATAATGGAGCAGACGCAGAGACAATCACATTCGGTCACCAccaaaactaatttaaaatccAACTCGAAATCCAACACTAAGAGCTCTAGCAGTAAAGTACAAAAACCTTTATCGAGTCAAAATGCGTCAATCAAACCATCATCTTCTAGTCCACAATCCAAAGTTACCAGTACAACCTCCCCAGGGAACAACGCCAGTTCCTCTGGGAAAGATCAAAAGCCTGTTGAGTGCAATTTGTGCCatagaaaatttaagaatataCCTGCTTTAAACGGTCACATGAGACTTCATGgtggatattttaaaaagGATACCgataacaaaaagaatgaaaagaaAGATCCAAACGGCCCACCTCTACAAACAGCCAGTGTGAGTGTACGGGCTCTCATAGAAGAAAAGATAATAAGTAAAAGAAACATAAGTTCCTCTTCGGATGATACATCATCACCAGTTAGGACGTCAGCTCCGCCTCTATTTCCTCTAACAGTCCATTCCCCAGTCACATCTGGAACCACATCAGAGGCGGATTCATCGAAAACTTCTTTTGCAGTTCCCGCGCCTCCTCAATTGAGTACGGTTGTAGAAAAAAGTAGAAGACATTCCGATGCGGAAACCTTCACGGTCCCCAGGACTCCGCAACAGGACGCCGATACTCTGGCGGATCTGATACTcaacaaaaaggaaaaagttaCCGTTAAAAGAACCACTTCCGATCCAGGCCAATCAACTCCTCAAATAATCCAATTCCAATCTGGCGAAGCGTTTACTTTGGGGGTCACCTATCAACCGGATGACGGTTATCTTTCGCCGAGCCTCCACGATGAAGTTTTCACCCAAGTACAAGATACAATGCTCCTACAAGGTGTCGATACCCAACAACTCGCTTCcattcaatttcaaaacatcGAAACTGATAGTCTTCTTCAAGATCACCCGGAGCAACAACTTCAAGAAATTTCGTTGGATGATTACAATCTACCTGACAGTGTAACGGATTCGCCTTCTTACCAATCAACGCAATCGGTGACCCATCAGGATTTAAGGGCGGTGTTGGATTCGCCACTTCCGGAAAGCTTGGCAGAGTTCAGTACTTTTCATACCACCGGAAGCTTGGATATTCCATCGCCGAGTTACCAAAGATCTCCAGCTCAATTCTCAAATTCACCACATCCTTCCATGGCGGCTCAAAGTCCTTTGCAATCCCCTCTGGTGAGACACGATTCACCAGCTTATACATATCCAACACCACCAGCGAGTCATGAGGGGCAAAGTCCTTGTTTTGGACAGAACACGATTCTTCCAATGGTTTCTCCAAAACAAGAGTACATCAAAGACATCGATCAAAACAATCAACTATTAACAACGGATTTCTTTTCCACGACAATGTCCAGTTCGGCAGCCGTTGAAGAGGCGTTAGAAGAAGTTCTTCCTGGTGAAAGTATAGCAGCTGATGATTTGTACTCGTCTCTATCAAATTCACCTCCACCTCAATCTCCTCTATCGATTGGTTTAACTCCCGTGCCTTCTCCTTTATCTAACATCCCTAGCACAACCGTTCCATCACCTCACActcaaacaaattttacatcAACAAACAATATACATTGTTTTCCTTTACAATCTCAAATGATGCCAAATTCAGACGATCCCTTGCTTTCGAGTAGCCCAAAAGATTTTCCGACGAAGAAGAAATTCGAATTTAACGGAAtcccattaaaattaatcagcGGTAATGCTATCATCGACAGCAACTTCACCGGGATCCTTCTTGATGCAAATGgggaattaaaattaatacaaaccGGTCCGAATGCATTTCATACCAAAAACATCGTTTTGGCGACTCCTCATATTATCACCCAACTTCACAATAATCATCCAAGCAAAGAAGAGgatgcaaataaaaaaatggttcCACCtgtaaaacaaattatacaaACCGTCGTTCCCACAGCAACAAAGCAAATCATTTTAACGAAACCAAAAGAtgttaaaatagaaacaatGAAACATgaagaagtttttttaagtCCAACAACtatatCCAGTAATTCTACAAAGAATCCTCGGAAAAGGCCTCGATCTGAACCGCTACAACTACCTATTTTACATCAATCAAGATTAAGGGCTACAAGAAGTAAACCACATGGTTCGTCGAGGTTTACACCATCTCCCATTTTAAACCCAAGTCGACCCGGAAATGGGTTGTATTGGAATATGAAATCTAAACCGATTGaTCCAGAAAACCAAGAAACAACATGGACCGATCCTGTTCCAGAAACCGACTCTACACCACACATAAACGTTGGGTCACATTTCCAAACCTTATTACCTCAATGCAGACCTTTGGATACTCGGTATGTTCAACAACCGACTAAAGAAGATCTTCTTTGGGATCCTggtataaataaatcaaaagaaGAGGTCGAAATGTATTTTGATTTTGCTTGCTGCGCTGCTCTTCCTGGCGGTGGAAGAAACCAAGAGTACGCAATGCACGTTCTCAACCTCTCCGATGGAAATATCCAtgAAGCAATGCTGAAATTGATGCAACCGACTCCGTCTCTGCCTTCTAAAAACCCCCTTCACGACTACCACTATTCAGAAACTGAAAAGTGGTCCGTCTTGGAGACCGATCTCTTCCAACAAGCTTTATCAAAGTATGGTAAAGATTTCGCAATGATATCCCAAGAAATCGGATCGAAATCGATGAAACAATGCGTCGAGTTTTACTATGTTTACAAAAAGATGTGTAAAGAGGATTATAAGGTAGCTAAACAGCTTAGAGAGAGATGGTCAAGTGCTGAAATTGAAGAGAAGCAGTTTGCCGATTCAAAATTACTTGGGATTGCAGACTCGGGATCACCTATAACTGAACAAAGAAGTTTTCCGTGCGAATTCGTGGATTGTTCTGcaagttttaattcaaaagcAGCCCTAAATGGTCACATTAGGATACATGGTGGCAGCGTGCGTAGTAATTGTCCGAATACGACATCCATCCAAGAAAGAAAGTTAACGTTGGTCACCTCAAGCAACCAGTGTCACAACAGCGAAACGATAGAAGATTATCCGTGTAAGATATGCGGGAAGAtattcacaaaaataaaaagtagaaGTGCTCATATGAAATCTCATCGGATACAAGATGAAGGCAGACGTGGTTTTTATTCCTTCGATCACGCACCAATCAATAATTCCTTCGGTACTTAG
Protein Sequence: MTAVNAGVHEITGVRLPLQHYTGSHAVFMYSTASDGNVTLQLKEPDDLDRTSLAAVLARLQDDSSFSISYQDADMLSDGSIDVLLGTGPGSQQGGGESVTTAPFDLFDSSNGPDLTLSPQTFTNSTEAFINDNSNSLGVPADNEAVSSTDEKKPSSLNSEASKLTVKRPRPKAVSPNRQGPQQCQVCSKVFGNASALAKHKLTHSDERKYICNMCGKAFKRQDHLNGHMLTHRNKKPYECKAEGCGKSYCDARSLRRHTENHHSSGSSNGATTMSPAQGAASGDAASPHGSSCIQYAPPPTTSVTSTTTTTTTSLGNSGSSNSTGKSQLQQLLATEPVKGGGANDGLTKQLDLIHQIMEQTQRQSHSVTTKTNLKSNSKSNTKSSSSKVQKPLSSQNASIKPSSSSPQSKVTSTTSPGNNASSSGKDQKPVECNLCHRKFKNIPALNGHMRLHGGYFKKDTDNKKNEKKDPNGPPLQTASVSVRALIEEKIISKRNISSSSDDTSSPVRTSAPPLFPLTVHSPVTSGTTSEADSSKTSFAVPAPPQLSTVVEKSRRHSDAETFTVPRTPQQDADTLADLILNKKEKVTVKRTTSDPGQSTPQIIQFQSGEAFTLGVTYQPDDGYLSPSLHDEVFTQVQDTMLLQGVDTQQLASIQFQNIETDSLLQDHPEQQLQEISLDDYNLPDSVTDSPSYQSTQSVTHQDLRAVLDSPLPESLAEFSTFHTTGSLDIPSPSYQRSPAQFSNSPHPSMAAQSPLQSPLVRHDSPAYTYPTPPASHEGQSPCFGQNTILPMVSPKQEYIKDIDQNNQLLTTDFFSTTMSSSAAVEEALEEVLPGESIAADDLYSSLSNSPPPQSPLSIGLTPVPSPLSNIPSTTVPSPHTQTNFTSTNNIHCFPLQSQMMPNSDDPLLSSSPKDFPTKKKFEFNGIPLKLISGNAIIDSNFTGILLDANGELKLIQTGPNAFHTKNIVLATPHIITQLHNNHPSKEEDANKKMVPPVKQIIQTVVPTATKQIILTKPKDVKIETMKHEEVFLSPTTISSNSTKNPRKRPRSEPLQLPILHQSRLRATRSKPHGSSRFTPSPILNPSRPGNGLYWNMKSKPIDPENQETTWTDPVPETDSTPHINVGSHFQTLLPQCRPLDTRYVQQPTKEDLLWDPGINKSKEEVEMYFDFACCAALPGGGRNQEYAMHVLNLSDGNIHEAMLKLMQPTPSLPSKNPLHDYHYSETEKWSVLETDLFQQALSKYGKDFAMISQEIGSKSMKQCVEFYYVYKKMCKEDYKVAKQLRERWSSAEIEEKQFADSKLLGIADSGSPITEQRSFPCEFVDCSASFNSKAALNGHIRIHGGSVRSNCPNTTSIQERKLTLVTSSNQCHNSETIEDYPCKICGKIFTKIKSRSAHMKSHRIQDEGRRGFYSFDHAPINNSFGT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01098431;
90% Identity: iTF_01098431;
80% Identity: iTF_01098431;