Basic Information

Gene Symbol
L
Assembly
GCA_036711965.1
Location
JASERS010000007.1:31037536-31042723[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 19 2.2e-05 0.0027 19.5 0.3 1 23 85 107 85 107 0.98
2 19 0.19 24 7.1 6.0 1 23 113 135 113 135 0.97
3 19 3.6e-06 0.00044 22.0 1.2 1 23 141 163 141 163 0.99
4 19 0.0013 0.16 13.9 1.3 1 23 169 191 169 191 0.97
5 19 0.0096 1.2 11.2 0.1 3 23 270 291 268 291 0.95
6 19 0.0023 0.29 13.1 0.2 1 23 303 326 303 326 0.93
7 19 8.1 1e+03 2.0 1.4 2 23 380 401 379 401 0.92
8 19 0.16 20 7.3 0.0 2 23 412 433 412 433 0.94
9 19 0.011 1.4 11.0 7.2 3 23 443 464 442 464 0.90
10 19 0.098 12 8.0 0.4 1 23 469 492 469 492 0.90
11 19 4.4 5.4e+02 2.8 0.3 1 11 499 509 499 513 0.89
12 19 2 2.5e+02 3.9 6.1 1 23 552 575 552 575 0.80
13 19 0.27 34 6.6 0.1 2 23 610 632 609 632 0.89
14 19 0.00052 0.065 15.2 4.6 2 23 646 667 645 667 0.97
15 19 0.00013 0.016 17.1 0.4 1 23 676 698 676 698 0.98
16 19 5.2 6.4e+02 2.6 3.0 2 23 706 727 706 727 0.96
17 19 0.00078 0.097 14.6 0.3 2 23 841 862 840 862 0.95
18 19 0.013 1.6 10.8 0.0 1 23 870 892 870 892 0.95
19 19 0.0031 0.39 12.7 1.0 1 23 899 921 899 921 0.97

Sequence Information

Coding Sequence
ATGAAACCGGATGAATTAGGAAAAAAGATGGAGGAATCAAGAAGTGAAAAaaacgaagaagaagaagatgagaGTGAAGGTTCAGAATTGGGGTGTCTAGATGATGAAGACGACGGTAGTGGCAGCGTGAACGGTCGCGCCAGTTCCCCTTCGAGCAGCAATTCCTCACCGGTTAGTTGTCGCAGTTTCGGATTAAGCGACGCCACTGACGTCGAAGAAACTTACACAGTCGGCGCCACCGCCACCACCCCCTATGAATGTAACGTTTGCAAACGAGCTTTTTCGAGGTCTTCAGTATTGGGCAAACATTTACAAgTCCACACGGACCAGCTACAATTTAGCTGCCCATATTGTAGGAGATTATTCAAGCATAAAAGATCAAGAGATCGACATACTAAACTTCACACGGGCGACAAGAAATATAAATGTGCGTTATGTGATTCAGCGTTTGCGAGGAGCGACCATCTAAAAATCCACATGAAGACGCACGACAACAAAAAGCCACACCAGTGTGATTTATGCAATAGAGGCTACAACACAGCGGCGGCTTTGGCTTCCCACCAACAACATCACACCAAAAAAGAACTCCGCTGCGGAAGTAGCTCAAGCAGAAATACAACTACCCCAAGCACCCCCAGTCCAGGTCAAACGAAGTGCTCACAAATCCAGGTGAGTACAAAACGATCTTCCACGGATTTTGATCGATGTGGAAGATCTTTTCAGAATAACTTAACGATCAAACGCAAACTTCCAACGCCAAACAACGATACTACCGTGCCGAAACAAGAAGTGGATCTTAAAATAGCTTGTATGTACTGCGGAAAAGATTTCGCGACGATGAACTTGATGTATCAACACATCAACATCGATCACTCCTCGTTGTTTTTTCAACACAGCTCGCTCAGTTACGTCTGTGATTTATGCTCCATGAAATTCGACACCTCCCAAACGCTAAGGGAACATTTAGAAGGTGTTCATTGGAAATTAAACACCGTAGGAACGTCATCCCAAGCGAAAGCCACCGATTTAAGCAGAAAAAGAAAATGTGATGAACCAGAAGATAACAGAAAAACCGAGGAGATTAAACACTCCCCATCGACAGTTAGTAGCCCATATGACACCAACGATAAGCCATGTATTTGCTCGTATTGTTACGCGCAAATGCCgaattttaaaagctttttggTCCATATGGAGACGCATGTTTCGTTGAATGCCTCAAGTTTAATTGGATATTGCCCGGTTTGCGGAGAACCGGGTCGAGATCCCATTGAATTCAGTTCCCACATTTTCGGACATGTCGTAAGCGATGCTACAGGAAGGTGTTGCCATCAATGCAAAAAATCCTTCGATCAACTCGATCAACTACAAAAACATCACTTTGAAGCACACTCCCAAAGCGTGTATAAATGCACGCTATGCGGGGAATACTTCGAAAATGAACTTGCTATTCAGgTTCACTTCAACAATAAACATTGCAACGAATGTAAACATTATAGATGTAATTTATGCCCCCAACAATTTTTCCACGATAGATTAACAGCCGATTTACATGTTTCTATGAGACACGGGTCCCAACTTTCCGGAAGAAACCAAATCTTAAACAAATTCGCTGCGCCATTTGGCGATGTTGAGCCAAGATTGTATCAATCGTACCAATGTTCATTTTGCCACAAAATGTTTCAAGACGAATACTTACACCATCTCCATATTTTAAAGGAACACAACGAATCGAGAGAAGGGGAGTATTTAGTGACATCGACATCTccaaatttttcttataaaagcatATCTCCTCAAGATGGCCTCAAAATGGTTCCTAATATCCCTTGCGAAGTCTGCAACCGATCAGATTTTACAACCGAATCCGAACTTTTAGCCCACAAAAAGCTGCATCAAACCCACGTCAAATCTAAAATAGGGGCAGTTAGCCTCCAGTGCGCGTATTGCAACGAACATTGCAAATCAAGAAACGACCTAGAAAACCACATGAAAACCCATCAAGTATCTTGCGGCAAAGGGAAACACAAATGCAATATTTGCGATGAGATTTTCTCATCCGCCATCACTTTAGCCGACCATAAATTAACTCATTGCAAAATCATCTCTGGAAATACATGCACACAATGCAAAACGGTTCTAGATGATGAGCAATGTTTTTACACCCACCAAATGCAGCATAACAACTCCTCATCAATCGCAAAGAGTCACTCTCAAATCCCTTTACCCGCAAATTGCGTAATTTGCTGTCAAACGCTTCAAACAGACGTCGAAGTACGATTACACGCCAAATTCCATTTACGCCACATTTACCAAAAAGAATTTCTTTGCGTAATGTGTAACAAAATCTACGAAAACCAACtccaagaaaaaaataacgGCGTTTCCATCTCAATTTGTAAAGATTGCAAAATGACCTCAAACGGAACCACCTTCCAAATACAAAAAGACTACAAGAATTTCGTCgaatacgaaaaagaacaagacATCAAATTGCGTCATATGGAAGATTCAAATTTAGTTTGCAAAATTTGTCGGAATGTTTTTTCAACTCAACAAAAACTTCAGGTGCACTTAATCGAGCACAATTTTATGGGTATGGGTCAATACCGTTGTTACGTTTGTTCTTCAGTTTTCACGACGGCGGCCGGTCTTCAAGGTCACATCGTAGGTCATGGATTGGCACAAAGTCCGTACGAATGTACCGAGTGCAACATGAAATTCTTTTTCGAAACGGAACTCGAAAATCATAGAATTAATCATGTGGCGCAAAAATTGGGCGAGTCGAAAAGCGAACAGTACAAAGTTTGCGAAAATTGCTCCGGTGTATATTTGGATAGCTTCTTCAGGGAGCACGCGGAAGTGTGTTGTAAGGTTGAGATTAAAACGGAGGAAGTTGATGATAAACCCTATGATAAAACGGGGGACGATTGCGGTGATGCTGTTTAG
Protein Sequence
MKPDELGKKMEESRSEKNEEEEDESEGSELGCLDDEDDGSGSVNGRASSPSSSNSSPVSCRSFGLSDATDVEETYTVGATATTPYECNVCKRAFSRSSVLGKHLQVHTDQLQFSCPYCRRLFKHKRSRDRHTKLHTGDKKYKCALCDSAFARSDHLKIHMKTHDNKKPHQCDLCNRGYNTAAALASHQQHHTKKELRCGSSSSRNTTTPSTPSPGQTKCSQIQVSTKRSSTDFDRCGRSFQNNLTIKRKLPTPNNDTTVPKQEVDLKIACMYCGKDFATMNLMYQHINIDHSSLFFQHSSLSYVCDLCSMKFDTSQTLREHLEGVHWKLNTVGTSSQAKATDLSRKRKCDEPEDNRKTEEIKHSPSTVSSPYDTNDKPCICSYCYAQMPNFKSFLVHMETHVSLNASSLIGYCPVCGEPGRDPIEFSSHIFGHVVSDATGRCCHQCKKSFDQLDQLQKHHFEAHSQSVYKCTLCGEYFENELAIQVHFNNKHCNECKHYRCNLCPQQFFHDRLTADLHVSMRHGSQLSGRNQILNKFAAPFGDVEPRLYQSYQCSFCHKMFQDEYLHHLHILKEHNESREGEYLVTSTSPNFSYKSISPQDGLKMVPNIPCEVCNRSDFTTESELLAHKKLHQTHVKSKIGAVSLQCAYCNEHCKSRNDLENHMKTHQVSCGKGKHKCNICDEIFSSAITLADHKLTHCKIISGNTCTQCKTVLDDEQCFYTHQMQHNNSSSIAKSHSQIPLPANCVICCQTLQTDVEVRLHAKFHLRHIYQKEFLCVMCNKIYENQLQEKNNGVSISICKDCKMTSNGTTFQIQKDYKNFVEYEKEQDIKLRHMEDSNLVCKICRNVFSTQQKLQVHLIEHNFMGMGQYRCYVCSSVFTTAAGLQGHIVGHGLAQSPYECTECNMKFFFETELENHRINHVAQKLGESKSEQYKVCENCSGVYLDSFFREHAEVCCKVEIKTEEVDDKPYDKTGDDCGDAV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01098704;
90% Identity
iTF_01098704;
80% Identity
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