Osag019344.1


Basic Information
Transcription Factor Domain
Sequence Information
Similar Transcription Factors

Basic Information

Insect
Onthophagus sagittarius
Gene Symbol
-
Assembly
GCA_036711965.1
Location
JASERS010000004.1:10133853-10142222[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.00023 0.028 16.3 0.4 2 23 110 131 109 131 0.97
2 16 0.0062 0.77 11.8 2.2 1 23 136 158 136 158 0.98
3 16 0.00028 0.035 16.0 1.2 1 23 164 186 164 186 0.97
4 16 0.00069 0.085 14.8 0.1 1 21 192 212 192 213 0.94
5 16 0.018 2.2 10.3 1.3 1 23 220 242 220 242 0.97
6 16 9.3e-07 0.00012 23.8 0.0 1 23 383 405 383 405 0.97
7 16 0.0039 0.48 12.4 5.8 1 23 405 427 405 427 0.94
8 16 7.7e-07 9.5e-05 24.1 1.2 1 23 433 455 433 455 0.98
9 16 8.8e-07 0.00011 23.9 2.0 1 23 461 484 461 484 0.96
10 16 0.0096 1.2 11.2 1.2 1 23 497 519 497 519 0.97
11 16 1.6e-05 0.002 19.9 4.6 1 23 525 547 525 547 0.97
12 16 1.3e-06 0.00016 23.3 0.5 1 23 554 576 554 576 0.96
13 16 0.00011 0.014 17.3 3.0 1 23 582 604 582 604 0.98
14 16 1.3e-06 0.00016 23.4 0.6 3 23 612 632 610 632 0.96
15 16 3.9e-05 0.0048 18.7 0.1 1 23 638 660 638 660 0.99
16 16 0.036 4.4 9.4 0.5 1 23 665 688 665 688 0.96

Sequence Information

Coding Sequence
ATGAGCCTTCAAAACAACTTTCAATTTTATCAGGATAACGATCCGAAGCATAAGGTCCATAATgtTGAAGAATCGGACAAACTCCCACACTTAATCTGCAATTATTGCGTGACACAACTAAAAGCCGCcgttaattttaaacaactttgcGAAGCCACCGATTTATTTTACAAACAATTACTAAACCTTCACATTGAACACAAAATTGAATTATACGAAGATATAATACTTTCTGCGGATACCTCAATAAAAGAAAGAGTCGATAAAGATAATTCAAATAACCGCGATTACATCCAAGTTCTCGATGACGAGAACATATTAATCCTAACTTGTGGGGAATGTTTAAAAGTTTTTACATCAATCGAAAGCTTAAAATCGCATAAACGCATTCATtctaaagaattatttaaatgtaaatattgCAATAGGGAGTATTTaagtttaaaaagtttaaatcgcCACGAATTGATGCACACAAAAAGGAAATTACACGTTTGTAAGATATGTAATATAACGATATCGCGGGATACTAATTTAAAGAAGCATTTGATGGTTCATTTGAAAGATAGGCCGTATCGATGCGAGGGGTGTACTAAAGGTTTTAATCGAGCCGAGGATTTAGatgttcataaaaataaatgtaaaggGCAAAAGATTTATACTTGTAATATATGCGCGAAAGGTTTTAATCGGGAGGATAGTTGTATGGTGCATGAGAAAATGCATGAAGATCAACAATACGTTCTTCCGACTTTAGAAAGTTTAGATAATATTCAGGAATTTTATTACGAAGTTGATCTAAACGATGataatattaatttgattaattcggAGATTTCCGATGGCGATGGGGAAGATGAATTTCAATCGGATATCGCTTGCGAGGTTTTATTTACCCCGATGGATGATAAAGATAAAGATCGAATTATAGATATTAAATCGGAAATTTATGCCGAAGAAGATCCGTTAGAAATAATGGAGGAAAAGGCTAGGATTGAGGAAGAGATGTATAATGGAAATAGTGATAGTGGGGAATCGGAATATTTTCCTTTGCGagtgaagaagaaaaaaggaaGACCTAGAAAAAAGCCGCTAAAAAAATTAAGGGGTagaccaaaaaaattaaaatcaaacgaAAATAACGAACACTCCTGCCCCGATTGCGACCAAGTTTTCCCCGATCCATCACTTTTAGAGGACCACATGATTAAACACGAATGCATTTATTGCAAAAAACGCTTCGCGAGATTCACTCATTTAAGACGTCACGTTTTAACACACTCCGAAAACAAACCCTATCCTTGCGCGCAATGCGAAAAATCATTCACAAGATTAGACCATCTCCAACAACACATTAAAGTCCACGACCCCGAATATAGGCACACCTGCGAAACTTGCGGGGTAACATTTTCGAGGCAAAGTCAACTCTCCCGGCACATGGTCACCCAACACAACGCCGAGCCATCGACGCAAGACGTcgagaaaaaattttattgcgaTATTTGCTTGAAAGGATTCACAACGGAAAAATATCGAAACGTTCACGTGAAAAATCACGAAGCCGGAAGACCGTTTCAGTgcaatatttgtaaaaaaacttTTACGTTAAAATCGCATCTTAATGAGCATGTTAAGTTTCATAGTGAGAGTTCGAAAAAGTTTTTATGCTCGGAATGTGGGCAGAGATTCATTCGGAACGATTATTTAATCATTCATATGAGGAGGCATCGCGGTGAGAAAccttttaaatgtaaattttgtgGGAAAGGATTTCCTCGGACTACGGATCTTCATGTGCACGAACGATATCATACTGGTGAGAAAACGCATTTATGTGGAGTTTGTGGACGTGGTTTtggaagggcTTACAATTTAAGAGTTCATATGCGAACTCATACAGGTGAAAAACCTTATCAATGCACATATTGTCCTGCTGCTTTCGCCCAAGGAAACGATTTAAAAGCGCACGTTCGAAGACATACTGGTGAACGATTTCAATGTGATCTTTGCGATGAAACGTTTTTAATGGGTTATTTATTAACGCAACATAAAAGATCCGTCCATGGATTAAACATAGTAGGAAATGTACGACGATTAACgcctataaaaaaatatgagatATCTGGGGAAGAACCAGAAACTGTAAGTTTACCTGAACCGGTAATTCTAGCAGCAGCTTTGCGTGGGACTCGATTGCAAACAGAACTAAAAATGGAATAA
Protein Sequence
MSLQNNFQFYQDNDPKHKVHNVEESDKLPHLICNYCVTQLKAAVNFKQLCEATDLFYKQLLNLHIEHKIELYEDIILSADTSIKERVDKDNSNNRDYIQVLDDENILILTCGECLKVFTSIESLKSHKRIHSKELFKCKYCNREYLSLKSLNRHELMHTKRKLHVCKICNITISRDTNLKKHLMVHLKDRPYRCEGCTKGFNRAEDLDVHKNKCKGQKIYTCNICAKGFNREDSCMVHEKMHEDQQYVLPTLESLDNIQEFYYEVDLNDDNINLINSEISDGDGEDEFQSDIACEVLFTPMDDKDKDRIIDIKSEIYAEEDPLEIMEEKARIEEEMYNGNSDSGESEYFPLRVKKKKGRPRKKPLKKLRGRPKKLKSNENNEHSCPDCDQVFPDPSLLEDHMIKHECIYCKKRFARFTHLRRHVLTHSENKPYPCAQCEKSFTRLDHLQQHIKVHDPEYRHTCETCGVTFSRQSQLSRHMVTQHNAEPSTQDVEKKFYCDICLKGFTTEKYRNVHVKNHEAGRPFQCNICKKTFTLKSHLNEHVKFHSESSKKFLCSECGQRFIRNDYLIIHMRRHRGEKPFKCKFCGKGFPRTTDLHVHERYHTGEKTHLCGVCGRGFGRAYNLRVHMRTHTGEKPYQCTYCPAAFAQGNDLKAHVRRHTGERFQCDLCDETFLMGYLLTQHKRSVHGLNIVGNVRRLTPIKKYEISGEEPETVSLPEPVILAAALRGTRLQTELKME

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01098665;
90% Identity
iTF_01098665;
80% Identity
-