Basic Information

Insect: Onthophagus sagittarius
Gene Symbol: Hr39
Assembly: GCA_036711965.1
Location: JASERS010000006.1:23726778-23738721[+]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 4 2 5.1e+04 -8.2 16.3 49 172 18 141 6 191 0.67

2 4 0.06 1.5e+03 -0.3 2.0 54 133 128 201 122 250 0.52

3 4 9.8e-09 0.00025 22.1 0.0 1 65 318 383 318 391 0.67

4 4 7.6e-73 1.9e-68 233.2 0.1 205 408 448 646 390 646 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	4	2	5.1e+04	-8.2	16.3	49	172	18	141	6	191	0.67
2	4	0.06	1.5e+03	-0.3	2.0	54	133	128	201	122	250	0.52
3	4	9.8e-09	0.00025	22.1	0.0	1	65	318	383	318	391	0.67
4	4	7.6e-73	1.9e-68	233.2	0.1	205	408	448	646	390	646	0.95

Sequence Information

Coding Sequence: ATGATTGGTCTTTCCCGTTCATTTCTAAAGAGTTCTAGATTCAAGTTAGTGCATACAAAActtccagaaaatctttcaatatctcaatcaacAAAACACAGTCAACTAAACTGCTCCTCAACCGATTTAAAAGAAAGTCCAGTTCTTCGATTGAAACAACCCATCACAAGTTCAGCTCACAATTACTCCATACACAGTACTCCGAGCAATTCGCCGCTGTTGAGTCAACGACAATCAAACCATCAGCTGCCGCCCAGCGGGATTCCGTCCTCAATGATCAGCCATAAAGAGCTGATGCATAAAGCTCTCAATGTTCCGCCGACTCCCAGCCCGGACTCCGCCGTTCACTCTGCTTACAGCGTTTTTAGTTCACCCAATCAAAGCCCATTAACTCAACGACACGTCACACTCACCCCGAATTTAAGCAGAAATAATAGTGATGCATCCCATTCGAGTTGTTATAGTTGTTCGAGTGTTTCCGTTTCCGTTTCGCCCACTCAACAATTTTCACCTACACATAGTCCTATACAggGTAGACATAATGTACCAAACTTACACAGTAGTCCATTACATCACCATGGAGTATTATATCGCAGCGTGCAAGATGATCAGAGTGTGCATTATTCGAATACTGAACACGAAGGTTTATTGTTGGACGAGCAGGAAGATAAGTCTGGGTTGGTCCACGCGAATCCTCTGACTGCGCAAACGGGGATTTCTCGTCAACAGTTAATAAATAGCCCGTGTCCGATTTGTGGCGATAAAATTTCGGGATTTCACTACGGAATTTTTAGCTGCGAATCGTGTAAGGGATTTTTTAAACGGACGGTGCAAAATCGGAAGAACTACGTTTGTCTTCGGGGCGCTGCCTGTCCTGTTACGGTTGCGACGAGGAAGAAATGTCCCGCGTGCCGATTCGATAAGTGTCTTAAATGCGGAATGAAGTTGGAAGcGATACGAGAAGATAGAACTCGAGGTGGCCGATCAACTTATCAATGTTCATATTCATTGCCTCCTTCATTAACCGGACATGGTGATCTCCGCGCGAGCTCGCAAGGTGATCTTAGGCACGGTTTAGGCGAACATTCCCATTTAACTGTAAAGTTGGAACCTCCGGACGTGGGGATATCCCCTCACTTATCCAGTAAAAGATTGGGTTCGCGACATGAAATTCCGCCATTATTGCAAGAAATAATGGGAGTGGAGCATTTATGGCATTACAGCGAATCCGAGCTAAATAAGTTAAACTCGGAGGGAACTTTATCGCGGGAAGGTTCGACGATACATAACCTTTCAACGCATCCTTTATTGGCCGGGACGGGATTGGCTGGTTCCGCGGATACCAATCCGGATTTCGTTGCAAATTTGTGCAATATCGCTGATCATAGACTGTATAAAATTGTTAAGTGGTGTAAAAGCTTgccattatttaaaaatatatccatcgACGATCAAATCTGCCTTCTAATAAATTCTTGGTgcgaattattattattttcttgttgtTTCCGCTCGATGGAGAATCCGGGCGAGATTCGGATATCTTTGGGGAAATCGTTGACTTTGGCACAAGCTCGCGATTTAGGCATGCAGGCGTGCATCGAGCGAATGTTGAATTTTACGGAGCAATTGCGGAGGTTAAGGGTTGATAAATACGAATATGTTGCGATGAAAGTTATTGTTTTGTTAACTTCTGATACATCTGAGTTAAAGGAGGCGGAAAAGGTTCGCGCTTCCCAAGAGAAAGCTTTAAAAGCCCTTCAAGATTACACCCTCGTTCATTACCCCGATTTGCCGGCGAAATTTGGGGAGTTATTGTTGAGAATACCAGAGTTACAACGAACATGTcagGCTGGAAAAGAATTGTTGACGATAAAAACAAAAGATGGGGAAGGTCCAAGTTTTAATTTGTTGATGGAACTGCTGCGCGGTGACCACTAA
Protein Sequence: MIGLSRSFLKSSRFKLVHTKLPENLSISQSTKHSQLNCSSTDLKESPVLRLKQPITSSAHNYSIHSTPSNSPLLSQRQSNHQLPPSGIPSSMISHKELMHKALNVPPTPSPDSAVHSAYSVFSSPNQSPLTQRHVTLTPNLSRNNSDASHSSCYSCSSVSVSVSPTQQFSPTHSPIQGRHNVPNLHSSPLHHHGVLYRSVQDDQSVHYSNTEHEGLLLDEQEDKSGLVHANPLTAQTGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCLRGAACPVTVATRKKCPACRFDKCLKCGMKLEAIREDRTRGGRSTYQCSYSLPPSLTGHGDLRASSQGDLRHGLGEHSHLTVKLEPPDVGISPHLSSKRLGSRHEIPPLLQEIMGVEHLWHYSESELNKLNSEGTLSREGSTIHNLSTHPLLAGTGLAGSADTNPDFVANLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSMENPGEIRISLGKSLTLAQARDLGMQACIERMLNFTEQLRRLRVDKYEYVAMKVIVLLTSDTSELKEAEKVRASQEKALKALQDYTLVHYPDLPAKFGELLLRIPELQRTCQAGKELLTIKTKDGEGPSFNLLMELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01098567;
90% Identity: iTF_01098567;
80% Identity: iTF_01097616;