Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 2.3 2.6e+03 -1.3 0.1 20 43 114 137 85 146 0.58

2 6 0.019 22 5.4 0.6 22 52 145 175 131 177 0.82

3 6 0.0015 1.7 8.9 0.2 24 49 206 231 197 235 0.80

4 6 0.075 84 3.5 0.1 23 48 234 259 228 261 0.84

5 6 4.9e-07 0.00054 20.1 1.7 17 49 257 289 256 293 0.85

6 6 0.0045 5 7.4 0.3 17 48 286 317 285 319 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	2.3	2.6e+03	-1.3	0.1	20	43	114	137	85	146	0.58
2	6	0.019	22	5.4	0.6	22	52	145	175	131	177	0.82
3	6	0.0015	1.7	8.9	0.2	24	49	206	231	197	235	0.80
4	6	0.075	84	3.5	0.1	23	48	234	259	228	261	0.84
5	6	4.9e-07	0.00054	20.1	1.7	17	49	257	289	256	293	0.85
6	6	0.0045	5	7.4	0.3	17	48	286	317	285	319	0.90

Coding Sequence: ATGGATAACTGGGTAGACCCATATCAATATGGTTCAGACACAGAATGCTTCACTCGAGCATTATGTTACAATCAAACCTCTGGTGGCAGTGTTTGGGAACAACCTTCAACATCTTTCACCGAAGGTCCTTATAATAATCATTATACTAATGAACCACAAAATAGTTCATATATTTCTCCATATAATGGTTACAATGGGGAAGGTCATTCTTTTATGCATCATCAAGGAAACTCTTTTGATCACTCACAAATTGTATATCCACCTGGAATATATTATCCTAACTCTCAGTATAATTATGCCATGCAGAAATCAAGTCCAGCAAAAAGTAGTGCTACAGCAAGCTCAAAAAAATCTTATCCTTGCACACAGTGTGAATTTATTGCTGACAAGAAGGGTGTCCTGAAGCGACATACAGCTTCTGAGCACAGGCACGACAAGGCAAACAAATGCCCTTATTGTCCTTATAGTTCAGTTCAAGCTGGATCACTTAGGACTCATTTAATTGCAAAACACCCTGATCGACCCCCTTATGCCTGCAGTAGGTGTGATTTTGCAACAAGTGAATCAAATGCACTGGATGCACATATTGCAAGCCAGCATGCTGGCGAGCTTACACCTTACAAGTGCCCACTGTGTGACTATACCGCCATACAAACTTCTGTCCTCCGTAAACACATTACCTCCAAGCACATAAAGGTAAAGCCTTACCAGTGTCCTCACTGCGATTATGCCACTGCTCTCTCAGGAAACCTAAAGGTACATGTGATGTCCAAGCATACCAAAGAGAAACCTCATCAGTGCCCACATTGCAAGTATGCTGCTGTACAATCAGCTAATCTCAGGCGACACATTGTTTCCCGTCATACCAAAGACAAGCCTCATCAATGCATTCTTTGCAATTACAGTGCCTCCCAGTCTGTTGATCTTAAAAAACATATGCTTAGGAAACACAACTCATAA
Protein Sequence: MDNWVDPYQYGSDTECFTRALCYNQTSGGSVWEQPSTSFTEGPYNNHYTNEPQNSSYISPYNGYNGEGHSFMHHQGNSFDHSQIVYPPGIYYPNSQYNYAMQKSSPAKSSATASSKKSYPCTQCEFIADKKGVLKRHTASEHRHDKANKCPYCPYSSVQAGSLRTHLIAKHPDRPPYACSRCDFATSESNALDAHIASQHAGELTPYKCPLCDYTAIQTSVLRKHITSKHIKVKPYQCPHCDYATALSGNLKVHVMSKHTKEKPHQCPHCKYAAVQSANLRRHIVSRHTKDKPHQCILCNYSASQSVDLKKHMLRKHNS

Sequence clustering based on sequence similarity using MMseqs2