Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.17 1.9e+02 2.3 0.1 16 48 93 125 81 128 0.79

2 7 0.06 67 3.8 0.3 21 48 127 154 122 156 0.84

3 7 0.042 47 4.3 0.3 16 44 151 179 139 184 0.73

4 7 0.12 1.4e+02 2.8 0.0 17 48 181 212 171 214 0.85

5 7 0.0057 6.3 7.1 0.2 21 49 214 242 211 247 0.90

6 7 0.0083 9.3 6.5 0.1 17 48 268 299 259 301 0.89

7 7 2.5e-06 0.0028 17.8 0.1 17 48 297 328 296 330 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.17	1.9e+02	2.3	0.1	16	48	93	125	81	128	0.79
2	7	0.06	67	3.8	0.3	21	48	127	154	122	156	0.84
3	7	0.042	47	4.3	0.3	16	44	151	179	139	184	0.73
4	7	0.12	1.4e+02	2.8	0.0	17	48	181	212	171	214	0.85
5	7	0.0057	6.3	7.1	0.2	21	49	214	242	211	247	0.90
6	7	0.0083	9.3	6.5	0.1	17	48	268	299	259	301	0.89
7	7	2.5e-06	0.0028	17.8	0.1	17	48	297	328	296	330	0.91

Coding Sequence: ATGGAAATCGACTTCTTCTCTCAAGATCTGGAAACTGTAGGCTGGAAAGGCAATGAAGTCTCTTCTAGATTACCACTGCCTTCATCTGTGTGCTATCACTGTGGCTTCACAGCTGATGGTAAGAGTGTCATCAAGGATCACATTGATCAGGAACATGCAGAGGTCTTTCTTCCCATTGACCAGACATCACACGTTGATACGAATAAGCAAAGGACCTATCTCTGCCAACATTGTGACTATACCTCAGCTAAGTCCAGTACCTTAAAGAACCACGTGAAATCCAAGCATACCGGCAGACGGCCGTACTCCTGTTCATATTGTGAGTACGAGTCAGCTGGATATGGCAACTTGAAGAGGCATGTTATGACAAAACATACAGGCGAGCGGCCTCATTCATGCCCGCATTGTGAGTATGAAACAGCTGAACCTGGGGCCTTGAAGAGACACGTGATGTCTAAACACACCGGGGAACGGCCACACTCGTGTCCACATTGTGAGTATAAATCAGCTGATTCTGGCTCTGTAAAAAAACACGTGTTATCTCAACATACCGGTGAACGCCCTTACAAGTGTACTTATTGTGACTACAAAACGGCTTTCTCTGGGCATTTGAAGAAGCATATGATGTTCAAGCATACTGGTGAGCAGCCTTATTCATGCCATTTTTGTGATTATAAGTCAGCTGAGTGTGGAACATTAAAAAGGCACATCAAGATGAAACATACGGGTGAACGGCCTTATTCTTGTACATATTGTGATTATAAATCAGCTGTTTCAGGTCACTTAAAGACGCACATACTGTCTAAGCATACTGATGAACGTCCTTATATGTGCCAATATTGTGATTACAAGTCAGCTCAGTCGGGCACTTTGAAAAGACACGTTATGTCTAAACACACTGGTGAACGACCTTATTCTTGTCCCTATTGTACTTTTAAAACCATTCAGACAAGAAATTTAAAGAAACACATAAAAGTCAAACATAAAAGCTAA
Protein Sequence: MEIDFFSQDLETVGWKGNEVSSRLPLPSSVCYHCGFTADGKSVIKDHIDQEHAEVFLPIDQTSHVDTNKQRTYLCQHCDYTSAKSSTLKNHVKSKHTGRRPYSCSYCEYESAGYGNLKRHVMTKHTGERPHSCPHCEYETAEPGALKRHVMSKHTGERPHSCPHCEYKSADSGSVKKHVLSQHTGERPYKCTYCDYKTAFSGHLKKHMMFKHTGEQPYSCHFCDYKSAECGTLKRHIKMKHTGERPYSCTYCDYKSAVSGHLKTHILSKHTDERPYMCQYCDYKSAQSGTLKRHVMSKHTGERPYSCPYCTFKTIQTRNLKKHIKVKHKS

Sequence clustering based on sequence similarity using MMseqs2