Basic Information

Insect: Oegoconia quadripuncta
Gene Symbol: fd96Ca
Assembly: GCA_949316235.1
Location: OX438744.1:8151059-8151814[-]

Transcription Factor Domain

TF Family: Fork_head
Domain: Fork_head domain
PFAM: PF00250
TF Group: Helix-turn-helix
Description: The fork head domain is a conserved DNA-binding domain (also known as a winged helix) of about 100 amino-acid residues. Drosophila melanogaster fork head protein is a transcription factor that promotes terminal rather than segmental development, contains neither homeodomains nor zinc-fingers characteristic of other transcription factors [1]. Instead, it contains a distinct type of DNA-binding region, containing around 100 amino acids, which has since been identified in a number of transcription factors (including D. melanogaster FD1-5, mammalian HNF-3, human HTLF, Saccharomyces cerevisiae HCM1, etc.). This is referred to as the fork head domain but is also known as a 'winged helix' [1, 2, 3]. The fork head domain binds B-DNA as a monomer [2], but shows no similarity to previously identified DNA-binding motifs. Although the domain is found in several different transcription factors, a common function is their involvement in early developmental decisions of cell fates during embryogenesis [3].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 1.2e-39 2.1e-36 124.8 0.0 1 88 12 98 12 98 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	1.2e-39	2.1e-36	124.8	0.0	1	88	12	98	12	98	0.97

Sequence Information

Coding Sequence: ATGCCGCGACCTTCGCGTGAATCATACGGTGATCAAAAACCACCCTATTCGTACATTTCGCTGACAGCGATGGCGATTTGGAGCTCCCCGGAGCGCATGCTGCCGCTGTCAGAGATCTACCGGTTCATCACGGACAGGTTCCCGTACTATCGCCGCAACACTCAGCGCTGGCAGAACTCACTGCGACACAACCTCTCCTTCAACGACTGCTTCGTGAAGGTACCGCGCCGCCCGGACCGACCCGGAAAGGGTGCCTACTGGACGCTGCACCCGCAGGCCTTCGACATGTTCGAAAATGGCTCACTACTCAGGCGGCGCAAGAGGTTCAAGCTGCAGAAGGGAGAGAAGGACAATCTGAACGCAGAGTTAGCGGCGCTGGCGAGTTTTAATCGCGCGTTCCTGGCACGGCAGGCTGGTGCACCGCCTCCGCCGGCTTTACCTTCGGCCAGTTTATACACTCCCCCGCTGTGTCCTCAAATGAGCCCGGAGCCAGCCGAGTTGGCGGAGATGGCGACAATGACGATGTTGCCACGCGAGAGACCGAGGCGAGCATTCACAATAGAGGCTCTGTTAGAGCCGGAACCACCGCGGTCATCTCCATCGCCGCAGCCAGTGTTGATGTCAATGCCGCGTGTAGAACTGATGCCCTCGCCGTACATGCTGGCAGCTCAGCGCTATCACGCCGAGCTGCTGCAGGCGGCGGCGCACGCGCTGCGGCCTTGCTACCTCCCTCCGCCGCCTCTCCCCGTCGCGTGA
Protein Sequence: MPRPSRESYGDQKPPYSYISLTAMAIWSSPERMLPLSEIYRFITDRFPYYRRNTQRWQNSLRHNLSFNDCFVKVPRRPDRPGKGAYWTLHPQAFDMFENGSLLRRRKRFKLQKGEKDNLNAELAALASFNRAFLARQAGAPPPPALPSASLYTPPLCPQMSPEPAELAEMATMTMLPRERPRRAFTIEALLEPEPPRSSPSPQPVLMSMPRVELMPSPYMLAAQRYHAELLQAAAHALRPCYLPPPPLPVA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00250273; iTF_01172142; iTF_00033634; iTF_01377282; iTF_00017989; iTF_01076197; iTF_00383431; iTF_00049709; iTF_00055213; iTF_00032719; iTF_00124976; iTF_00205873; iTF_00171570; iTF_01207923; iTF_01209017; iTF_00072059; iTF_00142907; iTF_00818172; iTF_00353889; iTF_00647809; iTF_00832716; iTF_01281118; iTF_00011753; iTF_00012746; iTF_00736433; iTF_01220466; iTF_01302101; iTF_00640092; iTF_00830977; iTF_01534606; iTF_00026658; iTF_00027573; iTF_01279998; iTF_00355939; iTF_00926403; iTF_01010179; iTF_00858359; iTF_01029027; iTF_00888026; iTF_00715621; iTF_01020037; iTF_00185121; iTF_00287873; iTF_00896584; iTF_01359530; iTF_01152862; iTF_00025087; iTF_00942623; iTF_00655905; iTF_00659275; iTF_00660120; iTF_00656953; iTF_00658170; iTF_00000994; iTF_01156098; iTF_01157479; iTF_01154829; iTF_01337587; iTF_00661091; iTF_00791011; iTF_00149188; iTF_00156067; iTF_00871108; iTF_01072260; iTF_00148297; iTF_00409099; iTF_00410093; iTF_00412333; iTF_00680334; iTF_00155124; iTF_00289436; iTF_00411231; iTF_00654047; iTF_00427908; iTF_00737284; iTF_00686149; iTF_01219596; iTF_00361423; iTF_00632573; iTF_00638463; iTF_01428863; iTF_01134596; iTF_01316132; iTF_01360420; iTF_01332355; iTF_00441295; iTF_00157011; iTF_00823736; iTF_01197533; iTF_01487524; iTF_01221305; iTF_00197189; iTF_00467269; iTF_00468006; iTF_00723782; iTF_00317926; iTF_00790054; iTF_01251558; iTF_00166759; iTF_00834439; iTF_00836330; iTF_00835360; iTF_00837280; iTF_00677352; iTF_01161128; iTF_00859272; iTF_01073416; iTF_01180136; iTF_00806505; iTF_01125257; iTF_01178217; iTF_00744417; iTF_01331241; iTF_01333542; iTF_00674122; iTF_00186955; iTF_00278923; iTF_00889003; iTF_00960747; iTF_01205515; iTF_01202284; iTF_01204685; iTF_01203855; iTF_01203057; iTF_01206366; iTF_00970220; iTF_00971046; iTF_01503660; iTF_00204941; iTF_00449933; iTF_01135565; iTF_01358701; iTF_00290478; iTF_00649838; iTF_00006895; iTF_00044271; iTF_00390191; iTF_00432943; iTF_00431943; iTF_00827791; iTF_01342031; iTF_00326896; iTF_00772688; iTF_01564368; iTF_00818961; iTF_01091505; iTF_01179313; iTF_01509393; iTF_00352850; iTF_00967858; iTF_01312050; iTF_00720019; iTF_00825395; iTF_00826635; iTF_01245747; iTF_01282035; iTF_01429747; iTF_00428813; iTF_00794132; iTF_01569076; iTF_00364725; iTF_01081397; iTF_00256662; iTF_00255626; iTF_00821590; iTF_01438710; iTF_01082248; iTF_01437779; iTF_00795515; iTF_01538550; iTF_00206807; iTF_00874263; iTF_00875112; iTF_00875964; iTF_00878679; iTF_00006104; iTF_00810808; iTF_00673305; iTF_00144378; iTF_00207674; iTF_00208642; iTF_01334568; iTF_00406522; iTF_00407376; iTF_01443643; iTF_00708986; iTF_01317091; iTF_00280943; iTF_00869434; iTF_00282079; iTF_01151872; iTF_00931035; iTF_00932230; iTF_01071451; iTF_00113148; iTF_00007820; iTF_00113941; iTF_00761436; iTF_01083109; iTF_01416583; iTF_01415633; iTF_01173084; iTF_01436828; iTF_01124413; iTF_01335741; iTF_01463069; iTF_00288670; iTF_00662046; iTF_00751838; iTF_00347327; iTF_01133534; iTF_01158526; iTF_01153666; iTF_00063391; iTF_00341149; iTF_00430431; iTF_00000128; iTF_00017155; iTF_00947712; iTF_00164134; iTF_00934547; iTF_01217305; iTF_00403578; iTF_01247898; iTF_00933535; iTF_00770917; iTF_00819868; iTF_00114751; iTF_00405742; iTF_00323302; iTF_00705798; iTF_01401094; iTF_00008711; iTF_00420359; iTF_01034344; iTF_00419595; iTF_00421163; iTF_00801611; iTF_00959981; iTF_00958516; iTF_00461367; iTF_00959224; iTF_01033532; iTF_00418781; iTF_00842461; iTF_00462183; iTF_01463973; iTF_00009816; iTF_00994183; iTF_01166407; iTF_00637289; iTF_00908625; iTF_00636084; iTF_00077301; iTF_00404506; iTF_00699911; iTF_00698082; iTF_00703748; iTF_00701766; iTF_00700814; iTF_00702703; iTF_00697137; iTF_00696309; iTF_00704762; iTF_00185951; iTF_00342024; iTF_00840136; iTF_01099688; iTF_01171275; iTF_01170380; iTF_00662900; iTF_01148649; iTF_01149390; iTF_01140755; iTF_01145877; iTF_01145116; iTF_01147230; iTF_01501898; iTF_00706755; iTF_00822698; iTF_00687723; iTF_01264210; iTF_00236461; iTF_01489953; iTF_00235684; iTF_00787432; iTF_00382381; iTF_00284339; iTF_00034517; iTF_00035453; iTF_00698989; iTF_01129869; iTF_01115526; iTF_01495596; iTF_00957776; iTF_01494134; iTF_01176025; iTF_01494875; iTF_01496381; iTF_00162318; iTF_00273422; iTF_00809870; iTF_00274258; iTF_00808915; iTF_00176919; iTF_00194991; iTF_00985808; iTF_01506978; iTF_01507877; iTF_00824518; iTF_01078886; iTF_01506151; iTF_00796335; iTF_00843311; iTF_01078002; iTF_00695288; iTF_01079705; iTF_01080542; iTF_00722851; iTF_00247854; iTF_00246995; iTF_00159640; iTF_00984840; iTF_00642155; iTF_01017550; iTF_00213231; iTF_00212237; iTF_00953330; iTF_00954221; iTF_01018390; iTF_01029968; iTF_00771686; iTF_01361392; iTF_01192433; iTF_00197938; iTF_01119090; iTF_00850404; iTF_01062565; iTF_01532838; iTF_01027111; iTF_01028072; iTF_01063560; iTF_00711625; iTF_00851529; iTF_01533744; iTF_01230322; iTF_01118067; iTF_00300980; iTF_00951605; iTF_01116981; iTF_00111414; iTF_00928470; iTF_00301911; iTF_00444920; iTF_00973532; iTF_01061692; iTF_01025789; iTF_01064445; iTF_01030943; iTF_01531775; iTF_00905923; iTF_00147111; iTF_00907689; iTF_00374987; iTF_00120299; iTF_00373720; iTF_01339769; iTF_01439705; iTF_01339770; iTF_01338299; iTF_00038508; iTF_01246636; iTF_01526828; iTF_00124048; iTF_01094709; iTF_00122167; iTF_00121208; iTF_00123161; iTF_00071214; iTF_00726095; iTF_01525743; iTF_00924401; iTF_00037587; iTF_01093848; iTF_01092877; iTF_00685242; iTF_00040605; iTF_00042441; iTF_00041590; iTF_00363837; iTF_00906869; iTF_00172542; iTF_00622622; iTF_00237277; iTF_00745438; iTF_00757950; iTF_01440798; iTF_00448831; iTF_00036434; iTF_00425184; iTF_00786579; iTF_00925544; iTF_01147923; iTF_01144370; iTF_01259891; iTF_01367507; iTF_01451283; iTF_01453091; iTF_01452150; iTF_00039604; iTF_00354900; iTF_00774324; iTF_00457057; iTF_00457825; iTF_00779330; iTF_00781636; iTF_00775078; iTF_00621034; iTF_00778604; iTF_00776589; iTF_00780077; iTF_00780850; iTF_01181715; iTF_00782453; iTF_00775865; iTF_00777817; iTF_00777248; iTF_00276085; iTF_01222294; iTF_01403254; iTF_00408208; iTF_00683137; iTF_00277186; iTF_00681475; iTF_00682179; iTF_00075271; iTF_00076265; iTF_00447978; iTF_00074290; iTF_01502783; iTF_00150295; iTF_00072536; iTF_00299960; iTF_01547340; iTF_00651544; iTF_01021000; iTF_00204185; iTF_00922710; iTF_01362905; iTF_00249530; iTF_00180263; iTF_01141466; iTF_01402554; iTF_01424858; iTF_00783237; iTF_00785827; iTF_01285357; iTF_00785012; iTF_00784214; iTF_01016379; iTF_00146204; iTF_00325180; iTF_01084060; iTF_01084948; iTF_00345629; iTF_00621831; iTF_01336637; iTF_00844130; iTF_00275060; iTF_01500916; iTF_00177889; iTF_00021150; iTF_00043294; iTF_01435871; iTF_01491690; iTF_01075183; iTF_00856414; iTF_01529008; iTF_00376914; iTF_01182482; iTF_00266996; iTF_00909558; iTF_00648921; iTF_01528091; iTF_00119420; iTF_00445920; iTF_00446928;
90% Identity: iTF_01463069;
80% Identity: -