Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 1.6e-18 8e-15 54.5 0.0 14 49 67 102 63 106 0.92

2 3 0.14 7.2e+02 0.2 0.0 13 32 144 163 133 171 0.76

3 3 2 9.8e+03 -3.5 0.3 37 44 252 259 246 261 0.59

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	1.6e-18	8e-15	54.5	0.0	14	49	67	102	63	106	0.92
2	3	0.14	7.2e+02	0.2	0.0	13	32	144	163	133	171	0.76
3	3	2	9.8e+03	-3.5	0.3	37	44	252	259	246	261	0.59

Coding Sequence: ATGGGAGTAGTAGaagtcgataaaatcgttagTCATAGTGCAAGGGATGGGaaCCTAGGCAAAAGGCTATATGAATTTACAACAATacaagatattttaataacagcAGAAATTGTGGCATTGCTTCATTCACAACAATGTCCAAGTTTACATTTAGATATACATACACTCTTGACGCAATTAATTTTAGGAGACGGACAGTCCAAAACTCGGAGCATGTCGGATCAGCCGATATCGTGCCCACTCTGTGGTGCGATGTTACGCCAATCGAGGAACTTGAGAAGACACTTGGAACTCCTACACTTTGGACTTGGGAACGGTAGCAAAGCTGGTCTACACGTAAGGCATCGAAGGAACGACAGAGGCGGAAATTATTTTAGACCCTCCTTGCCATGTATTCGTACCCCGCATGCATCCAGAACGGACTCGCATCATCCAAGAGCATCCGAGCACTCGGATTTCCCAACGATGACACCTTTATCAGTAGCTTCTACGGTGAGCTCCGGCCATCTCATGGGAGGACCAGGCTCGAGCATGTTAGGCTCCGCTGATCAGAACGCACATTCCATTTCTACGGCTTCTGCTACTTCGTGCGGCGTTTCCATGGGACCAGCCAACAACGGGATTTACACGTCGGATACCAGTGCCAGTATGCTGGGCTGTTTACTACCGTCTTTGCCTTCACTGCCTTCGCTCTCGTCTCCTCACGATGTTTTCCGGCACGGTGAAATGTTGCGAGCGTATCATGACCCATCGAGACAGCACGCTAGACACTTGCAACGTACCGACGTTACCTAA
Protein Sequence: MGVVEVDKIVSHSARDGNLGKRLYEFTTIQDILITAEIVALLHSQQCPSLHLDIHTLLTQLILGDGQSKTRSMSDQPISCPLCGAMLRQSRNLRRHLELLHFGLGNGSKAGLHVRHRRNDRGGNYFRPSLPCIRTPHASRTDSHHPRASEHSDFPTMTPLSVASTVSSGHLMGGPGSSMLGSADQNAHSISTASATSCGVSMGPANNGIYTSDTSASMLGCLLPSLPSLPSLSSPHDVFRHGEMLRAYHDPSRQHARHLQRTDVT

Sequence clustering based on sequence similarity using MMseqs2