Basic Information

Insect: Odontocerum albicorne
Gene Symbol: egg
Assembly: GCA_949825065.1
Location: OX463866.1:19263276-19350652[+]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 2 0.36 2.7e+03 -0.9 0.0 29 38 1818 1827 1801 1828 0.83

2 2 2.7e-13 2e-09 37.9 0.0 5 71 1860 1919 1856 1924 0.87

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	2	0.36	2.7e+03	-0.9	0.0	29	38	1818	1827	1801	1828	0.83
2	2	2.7e-13	2e-09	37.9	0.0	5	71	1860	1919	1856	1924	0.87

Sequence Information

Coding Sequence: ATGGCTTCGAACAACGATCAAGACCTTTCCAAGGAGAGTATGGATATAGACGATCTGTCTTTGGAAGCATCAATGGAAGATTCGGCGGAGAAGACAGGAAAAGTTGTCGAGACGTCTGATAAAGTTGAAACTGAAAACGATATAGAGAATGCCCTTTTGAATGATTCCTCTGATGGTGAAAGCACATTTTTGGGATTCAAGTTAGACTTTGATAGTCCAGAGAAACccaaaataaatactgaatcaAATAAGGAATGTAAAACAGTCGAGGATCTAAAAACAATTGAATCAAAAACAGTTGATGATCTAAAAACTCTTGAATCTAAAACAGATGAAAGTGTCGAAACAGTTGATGATCTAAAAACTCTTGAATCTAAAACAGATGAAAGTGTCGAAACAGTCGATGATCTAAAAACTCTTGAATCTAAAACAGATGAAAGTCTCGAAACAGTTGATGATCTAAAAACTCTTGAATCTAAAACAGATGAAATTGTAAAAACAGTTGATCTAAAAACTCTTGAATCTAAAACAGATGAAATTCTAAAAGCAGTCGATGATCTAAAAACTCTTGAATCTAAACCGGATGAAATTCTTGAAACAGTTGATGATCCGAAAACAAGTGAAGATCAAATAGAAAGTAAATTAAAGGAAAGTTCGATTAAAGAAAGATTAGAAACAGATGATAGTAGTCGAGACGATAAAGGAAAAGAGGAACGTAGTGgtgttgaaaaatgtttaagtattGAAAAGACCGTTGAGGAAGAATTCAGAATAGATGACAGATCTCCTGAAAGAATACCAGAAAAAGAATCGACAAGGAATGAAAAATTGGATACTGTAGAAGAAAAACAGTTATTGAGCGATTCAAGTGTAATTGAAGGTGAAACTAGCGCAAGTATATCCAACGTGACCGAATACTTTTCCAAAATTGAAGATGAACTGTTGAAAAGTAACGATTTTGATCGCATAATCAACGAGTTTAGTAGTTCACTGTCGAAAGGAGATGCTGTATCCGAGGTCTCGTCGAGGATAGATAATATATCGAATGAATTTGACGACGATGATACTAGTTTTTCTGGATCCAATTCAGCTGTGCAAAAAATCATCGCTAGCAAATTTGCCGATATCGAACAAACTATATCGGATATCACCGCAGATCTTGGTAGTGATGGAAACAAAAATGTACaaagtgacgaagaagacggagaAAGTTCAACGTCGGAAGCGAAAGAGGATTCGAACGATAATATGAGTACCGAAGAAGTTCTTAAAGATAATTCAAAAGAGAAAGCAGAGGTTGATGAAGATATAAGTGGGGATGATGGATCTAAAGATGGGGTACAGACCGAGAAAGAAGGAGGTGAACATGGCAAAAGTAAGAAATCAAGCGCGTTGGCTGAAATTAAAGCGAAGAACGATCAACAGATGGTCGACTTGGAAGACGCTTCAATGGACGGAGCCCATGAAACGGATGCCCTGGGCCTGTTGGCAGAGGCTGAAGGCAGAGAGAGGCACTCCTCAGaccctgatgatgatgatgaagaggACGATGATGTCACCTCGGAAAGGGACAGCATGGAATCACATAACTATGCGAGTGAACGAGAAGAGTCTGCGGATGACCCAGATGAAATGACAGAACCCTCGGATGAAGACTACGATCCCATAGCTGAGGATGATCTTGATGAAGATGACGACATTGATGAGGAAGACGAGGATGGATTGAACTTCCGTGGCAACTTCCGCGGCACGTCTAGAGGCGGACAGAAACGTAGGAGGTCCGTCGTAGACCCACCGCCGGATATGAGAACGGAGAATGAATATTCTATGCAGATAGAAGAAGAAACTAGTCAAGGTAATGCGGAACTACAGAATAATTCAGAACTCAACGAAGATACCGCAAATCAAGATTTGTTGCCGAACGATGATATGGAATTAGATGATACCGTTGGGCAGAATATACTATCTATATGCAACGTCACAAGTTTGTCCGTGGATCAAAACGGTGTCGAACAGTCTCTGGAAGAGGCTGAGAATGATTTGGAAAGAAACGACGAAGAAGAGGCTGAGAATGATTTGGAAAGAAACGACGAAGAAGAGGCTGAGAATGATTTGGAAAGAAACGACGAAGAAGAGGCTGAGAATGATTTGGAAAGAAATGACGAAGAAGAGGCTGAAGCGAACTTAGTTATCACCTCATTTGGCACAGCGGATGAAGAGATATTGAAGAAACTTAACGAAACCGTTGATGATAAAGCGGAAATCGGAAAAAAATCTGATGAAATAGATTCGAACGACGCTGAAGTCACAACTCCAACAGCCACCGATGAACAGATCAATGTCGGAGCGTCTGAAGGTGTTGTTGAATCTCCGAAAGATAAAACGGACACTGAAACATCGGCTGACGATACTGCAGACTTAATGAATGTCTCTCAAGAGGAGGAGATTCAGAATCTGTGGGACTCCATCATGGAAGGGGACAGTAATAAAGAGATCAGTAATAAGAGAAAGGCAGACGATAGTTTAGAGAAGGCGAGGAAGAAATTGGACACTAAACAAGTGTCGGAAGAGGTAGACGATGATGTTTTGACCTTTGCCAGGGATCACGGAAAAGTTTTTCCCGCTGTGGAAGATGCTCAGGACCACAGTGATAAGCCGGATGACCTGAGCACCACCCTCGATAGACTGACCCAAGTCCTTGAGAAGTCGCCCGAATCACCGGTCCCTGAGGAGTCTGTGGAGAAGACAGTTCAACCGGACAAGGTTCTGCTTATCAAAGAGGAGAAAGACGCAGATGCTTATGTGGAAACACCTTCGAAAGATCTTTATATGTCGATCGGCTTGACAGTGAAGGTGGAGAAGCCAGATGAGGCGCAGCCAGTGGCGACCGTCGATACGGCATGTCAGCCTGCCGCGCCCTCTTCCATGGACTTGGATATACCTGCTGAAGtaaatataaaagtaGAACCGGCGCCCAGTGAAAAGAAGACCGTTGAGACTGAACCAAGCCAGGCAGTGGAGACAGAACCAGTGCCGGATGTCAAAGAGACGGCTATTCCTGCAGATACTGTTCCTGTAGTAGCCGTAGCGGAACCTTCACTCGAGCCTGCCTTGGTGCCGGAGAAACCTGTTGAATCCAGCGAACCACCTGAAAAACTTGATGTTGCAGTACCTTCGGAGaagcCACTTCCCAAGAGTGAAAAACCCATCGCAGACGTAGTGACAACTCCTGCAGCATCTAAGATTGATGAAGTCGTAACCAAGCTTGCGACAAAGCCGGTGTCTGAGGTGTTCTCCCTGGACTCTGACGATGAAGATGAGGCAGCCAAGGCCAGCCCTGTTCAAGtttcgCAGCAAGAGGCAATTAAGAAACTCGATGACCCGTCTCCTACCAAAAAAGATCTCTCGCCCCGCAGTCGCGATCAAGTGGCCGTAAAGGGCGACCGCGGCAAGTGCGTGAACCCAGCATGTGTGAGCGCTGCTGCACCGCATCCGTGTCCCCTGTTCCTGCCCTCGCTGTACCGGGCCAGGGACCTCACCAAGGCACCTCTCGCCTGCAAGGAGTGCCTCGACAGGGGCGTAGCCCTCATGGAGCTGCTGACGTCCCGTCTCCGTGCAGGCGTATGCCTGTTCACCGTGGATATGCCCAACACTGGAGAGCTGGTGGAGATATCCGACTCTGACTCGGAGAACGAGTCCGATCCGAGTGGGGGGCGCCGCGTGAAGAAGGGCGCGACCCGCAAGTGGGGCGGCCCCACCCTGCCGAAGGAGGAGCAGCAGTTCCTGCTGGATAACCTTGAGGAGGTTTTCGCATCGACGTGGAGCAGGCACCGGGTGCACGACCAGTTACGACTGTGCGAAGATAAGCTTCACGCTCAAGTCGATGCTCTCCAAGCCGAGTCCCGAGAGCTGGGCAAGCTGATAGACGCGGAGCAGACCGCACTGGACGTTATGAGGAAGACCCTGTACGAGACCTTCAAGCCAGTGACCGAGTGCCGCACCGAACTCATCATTTCCGACAACGGAGACAAACAGATTGAAGTGAACCTGATGGTGGAACGCAGGTCAGCGAGGATCAGCAAGAAGCAGGCTCAGTACTTGGACGAGGATATGTTCAAGGACCAACCGCTGCCAACGGCAGACAGTGTGGAGGTGGACGACCCCAATGCTGTCACTGAAGTCAATCCGGAAaCTCTGCCCCCAGAAGGCCTGCTGCCAGAGCAGCCGCTGCAGGTGGGAGACACTGTATACGCCGTGAAGCAGTCCATCTTCGGGGCGTGGTGTCCCGCAAAGATCGTGCAGGTCTTGCCCAAGGGGACTCCCTTGGCCAACGGGACGCTGTCTCTGTTCTCACTTGTTCGTGTGAGGTTCGTGCAGGGTGCGGAAGGGGGTCGCGCGGCCAAGCAGGTCACCGGGAGACAGGTGGCCTACCCTGAACCCGCTGATGTTAGATATCCCATCGGTACTCGTATCATCGCCCTGTTCAAGGACAAGAAGCAATTGAAGGAGGCCTACTACTCCGGGGTCATCGCAGAGGTGCCCATCAAAACCAACTTCTATAGATACCTGGTATTTTTCGACGACGGTTACGCCCGCTACGTGTCGCACAAGAGCGCTCTGCTCGTGTGCGAGCGTTCGTTGCGCGTCTGGGAGGACGTGCACCCTGACTCGCGCGACTTTGTGCGCAAGTACCTACAGGGCTTCCCCAACCAGCCCATGGTGCGGGTACAGCTGGGCCACTCCATTCGTGCCGAGTACAACGGCAAGTTTTGGTTTGCCCACGTGATGTCCGTGGACGCGTCACTCGCACTTATCCGATTCTCGGAGGTGAGCGGAGCCCCCATCACCCGGGAGGAGTGGATCTACCGGGGCAGCACGCGGTTGGAGCCCCTCTTCCTGGAGCTGCAGGCAGCTGACAGAAGGGCGCACGGCCGACACAGGGCCACTTACGCTACAACGCATCCCGCCAAGAATAAGAACTTCCCGTACGTGGAATACTCCAGGCCTGACCAACCCGAGGATCAGCAGCAACAGCAGACGGATGAAAAGGAGAACCAGGCAAGCATTcgagattatatttctttAGTTGCCGTCACTGCCGACTCTGATGACAGTGATTTTAGTGTCGATTCTGACGATGAGGAACCAGATGTGTCGAACGTTCCCGGGTTTGATGAAtcggcaccagtttttgaaTGGAAAACGGATGACTTTATTCCCATTGTCAACTCGTTCTCTAGCTCAAAATCAGGAGCGGATGTAGAGAGTGTTGGTACCAGAGAAGAGGCGACCAAAGTGGAAGAGGAAAATGTTCAACAGGCGGCCGTGAGCCGTGCCGTGGCCAAGAAGAGCACCAGCGTTCCGGCTCCCGCCCCCCCTGTCAAGGAGGATCCGCCTCGCGCCAAGGAGCGCGAACAGCAACCCCCTGCCCAGCAACTGCACGCTGATCAGGTCAAGAGCAAAGTGGTGTACTACTCGCCCAAGGTGTCGATCAAGCCCAAGAAGATGGTGCCGCACACGTGCGGGTCCGACTGCTTGAACCGGGTCGCGATCCCGCTCAGGGAGTTGAGAACGTACAATCCTCTCGCACGACCACTGCTCTCCGGGTGGCAGAGGTTGATCCTGAAGTACCGGGGCAAGCGCAGCATCATGTACCTGTCGCCGTGCGGGCGCCGTCTGCGCTCCTCGCAAGAGCTGCACCTGTACCTGCGCCTCACGCACTCCCAGATGAGCGTGGACTTGTTCGACTTCGATCACTGGGTGCATTGCCTGGCTGAGTTCGTTCCCACAAAGTGCTTTGTCAGCAAGAAGGATCTATCCCACGGCGTGGAAGCCGTTCCGGTGCCGTGCGTGAACTACTACGATCATACACTGCCGGAGTTCAGCGCGTACAGCACCCGGCGCATCCCCACTCAGGGGGTGCACCTCAACCTGGACGAGGAGTTCCTTTGCGGCTGTGACTGTACTGATGACTGCCAGGACAGGAACAAGTGTCAGTGCTGGCAGCTGACCCTGGAGGGCGCGGAGCTGGTGGGCTGCCAAAGGGACAGGGTGGGGTACCAGTACAAGAGACTGTTGGAGCCCGTGCCCACCGGCATCTACGAGTGCAACTCCAGATGTAAATGTGCGGCCACGTGCCTCAATAGGGTGGTGCAGCATCCTCTACAACTCAAGCTACAGGTGTTCAAGACCTTCAACCGGGGATGGGGAATCCGAGCATTGAACGACGTGTCCAGGGGTACTTTCCTCTGCATCTATGCTGGGAATCTGTTGACTGATGCGGTCGCTAATGTTGACGGCGTGACGGAAGGAGACGAGTACCTGGCGGAGCTGGACTACATCGAGGTGGTGGAGAAGCTGAAGGAGAACTACGAGTCGGACGTGCCTGAGGAAGACAAAGACTTTGATGAAAAGTCTGATGGGTCTGATGGAGAGGGCAAGGCTGCGCCGATGCACCGGGACGGTAAGACTGGCGCCCACGGAGAGTCCGACGAGGAGTTCCAGCCCACCACCTACATTCCCAAGGGGAAACCAAGCGACAGTGACGATACTCGTATGACCACGAGACGCCAGCTGAGGAAAAAGCGCGGGGAAAAGGATGGAGACAAGGAGAAAGAGAAAGAAAAGGAAATGGAAAGGAGGGAGAAGGAGAGGAAAGAGGAGAAAGAGAAGGAGCAGGAGAAGAAGGAGAAAGAGAGGCGAGAGGAGAGGCAGAGTAAGGACTCGGACTGTATAGAGGGGGTGGCGCCTGTCGTAGACGAGTTCATCACCATTAGCGATGACGAAGAGAACATGCGAGAACCGTCACGTTTTGCCGCTCCTGAGGGACTTAATGACGATGAATATGTGCCCAAACACAGATCAGTGCGTGGCTTCTTCGGCAAGGACGAGGCCTGCTACATCATGGACGCCAAAGTGCAGGGCAACCTAGGCAGATACCTCAATGTGAGTACACCACATTAA
Protein Sequence: MASNNDQDLSKESMDIDDLSLEASMEDSAEKTGKVVETSDKVETENDIENALLNDSSDGESTFLGFKLDFDSPEKPKINTESNKECKTVEDLKTIESKTVDDLKTLESKTDESVETVDDLKTLESKTDESVETVDDLKTLESKTDESLETVDDLKTLESKTDEIVKTVDLKTLESKTDEILKAVDDLKTLESKPDEILETVDDPKTSEDQIESKLKESSIKERLETDDSSRDDKGKEERSGVEKCLSIEKTVEEEFRIDDRSPERIPEKESTRNEKLDTVEEKQLLSDSSVIEGETSASISNVTEYFSKIEDELLKSNDFDRIINEFSSSLSKGDAVSEVSSRIDNISNEFDDDDTSFSGSNSAVQKIIASKFADIEQTISDITADLGSDGNKNVQSDEEDGESSTSEAKEDSNDNMSTEEVLKDNSKEKAEVDEDISGDDGSKDGVQTEKEGGEHGKSKKSSALAEIKAKNDQQMVDLEDASMDGAHETDALGLLAEAEGRERHSSDPDDDDEEDDDVTSERDSMESHNYASEREESADDPDEMTEPSDEDYDPIAEDDLDEDDDIDEEDEDGLNFRGNFRGTSRGGQKRRRSVVDPPPDMRTENEYSMQIEEETSQGNAELQNNSELNEDTANQDLLPNDDMELDDTVGQNILSICNVTSLSVDQNGVEQSLEEAENDLERNDEEEAENDLERNDEEEAENDLERNDEEEAENDLERNDEEEAEANLVITSFGTADEEILKKLNETVDDKAEIGKKSDEIDSNDAEVTTPTATDEQINVGASEGVVESPKDKTDTETSADDTADLMNVSQEEEIQNLWDSIMEGDSNKEISNKRKADDSLEKARKKLDTKQVSEEVDDDVLTFARDHGKVFPAVEDAQDHSDKPDDLSTTLDRLTQVLEKSPESPVPEESVEKTVQPDKVLLIKEEKDADAYVETPSKDLYMSIGLTVKVEKPDEAQPVATVDTACQPAAPSSMDLDIPAEVNIKVEPAPSEKKTVETEPSQAVETEPVPDVKETAIPADTVPVVAVAEPSLEPALVPEKPVESSEPPEKLDVAVPSEKPLPKSEKPIADVVTTPAASKIDEVVTKLATKPVSEVFSLDSDDEDEAAKASPVQVSQQEAIKKLDDPSPTKKDLSPRSRDQVAVKGDRGKCVNPACVSAAAPHPCPLFLPSLYRARDLTKAPLACKECLDRGVALMELLTSRLRAGVCLFTVDMPNTGELVEISDSDSENESDPSGGRRVKKGATRKWGGPTLPKEEQQFLLDNLEEVFASTWSRHRVHDQLRLCEDKLHAQVDALQAESRELGKLIDAEQTALDVMRKTLYETFKPVTECRTELIISDNGDKQIEVNLMVERRSARISKKQAQYLDEDMFKDQPLPTADSVEVDDPNAVTEVNPETLPPEGLLPEQPLQVGDTVYAVKQSIFGAWCPAKIVQVLPKGTPLANGTLSLFSLVRVRFVQGAEGGRAAKQVTGRQVAYPEPADVRYPIGTRIIALFKDKKQLKEAYYSGVIAEVPIKTNFYRYLVFFDDGYARYVSHKSALLVCERSLRVWEDVHPDSRDFVRKYLQGFPNQPMVRVQLGHSIRAEYNGKFWFAHVMSVDASLALIRFSEVSGAPITREEWIYRGSTRLEPLFLELQAADRRAHGRHRATYATTHPAKNKNFPYVEYSRPDQPEDQQQQQTDEKENQASIRDYISLVAVTADSDDSDFSVDSDDEEPDVSNVPGFDESAPVFEWKTDDFIPIVNSFSSSKSGADVESVGTREEATKVEEENVQQAAVSRAVAKKSTSVPAPAPPVKEDPPRAKEREQQPPAQQLHADQVKSKVVYYSPKVSIKPKKMVPHTCGSDCLNRVAIPLRELRTYNPLARPLLSGWQRLILKYRGKRSIMYLSPCGRRLRSSQELHLYLRLTHSQMSVDLFDFDHWVHCLAEFVPTKCFVSKKDLSHGVEAVPVPCVNYYDHTLPEFSAYSTRRIPTQGVHLNLDEEFLCGCDCTDDCQDRNKCQCWQLTLEGAELVGCQRDRVGYQYKRLLEPVPTGIYECNSRCKCAATCLNRVVQHPLQLKLQVFKTFNRGWGIRALNDVSRGTFLCIYAGNLLTDAVANVDGVTEGDEYLAELDYIEVVEKLKENYESDVPEEDKDFDEKSDGSDGEGKAAPMHRDGKTGAHGESDEEFQPTTYIPKGKPSDSDDTRMTTRRQLRKKRGEKDGDKEKEKEKEMERREKERKEEKEKEQEKKEKERREERQSKDSDCIEGVAPVVDEFITISDDEENMREPSRFAAPEGLNDDEYVPKHRSVRGFFGKDEACYIMDAKVQGNLGRYLNVSTPH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -