Basic Information

Insect: Ochropleura leucogaster
Gene Symbol: CTCF
Assembly: GCA_958449745.1
Location: OY288200.1:2190780-2203276[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.0022 0.17 13.1 5.9 1 23 184 206 184 206 0.98

2 11 2.1e-05 0.0017 19.4 1.3 1 23 212 234 212 234 0.98

3 11 8.2e-05 0.0065 17.6 1.7 1 23 240 263 240 263 0.96

4 11 0.038 3.1 9.2 3.2 1 21 269 289 269 291 0.95

5 11 0.00012 0.0097 17.0 2.7 1 23 297 319 297 319 0.99

6 11 1.6e-05 0.0013 19.7 5.3 1 23 325 347 325 347 0.98

7 11 0.0037 0.3 12.3 0.9 1 23 355 378 355 378 0.97

8 11 0.02 1.6 10.0 4.3 2 23 385 406 384 406 0.96

9 11 5.4e-05 0.0043 18.1 2.9 1 23 412 434 412 434 0.98

10 11 5e-06 0.0004 21.4 1.7 1 23 440 463 440 463 0.95

11 11 1.5e-05 0.0012 19.8 3.9 1 23 477 499 477 499 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.0022	0.17	13.1	5.9	1	23	184	206	184	206	0.98
2	11	2.1e-05	0.0017	19.4	1.3	1	23	212	234	212	234	0.98
3	11	8.2e-05	0.0065	17.6	1.7	1	23	240	263	240	263	0.96
4	11	0.038	3.1	9.2	3.2	1	21	269	289	269	291	0.95
5	11	0.00012	0.0097	17.0	2.7	1	23	297	319	297	319	0.99
6	11	1.6e-05	0.0013	19.7	5.3	1	23	325	347	325	347	0.98
7	11	0.0037	0.3	12.3	0.9	1	23	355	378	355	378	0.97
8	11	0.02	1.6	10.0	4.3	2	23	385	406	384	406	0.96
9	11	5.4e-05	0.0043	18.1	2.9	1	23	412	434	412	434	0.98
10	11	5e-06	0.0004	21.4	1.7	1	23	440	463	440	463	0.95
11	11	1.5e-05	0.0012	19.8	3.9	1	23	477	499	477	499	0.97

Sequence Information

Coding Sequence: ATGCCACCTCCAATTAAAAAGGAGAAAAACAAGCCAGCGCTCATTCAAACATACCAAGGAGCGGTCATCACAGTCAACGCAGCTACAGATGATAAAAGCTTGCCTACTGGAATGGTGGAGTATTTCGTAGATGAAGATGGGAAGTACTACTATCAGTCAGCGGTGGGAGGGCAGACCCTAGTCATGAATACTGAAGGCAACCAAGAAGATGAGGAGGTTGCTGAAACGTCGGACCCGATGTTGACCGAGCAAGGGGAAACGTATCAAACGGTCGCCTTCCTCCCCACGGAGAACAACGGGGAAGTTAGTTATGTGCTTGTAGTCCAAGAAGAGAACAAGGGGGGAGTCGTGAACATGGAACTCAAGGTGGACCAGGGCCGGGAAAACGTCAAGACCGAGGCTGAGGAGAAAGCCAACGATGACGTGTACAACTTTGATGAAGAGGAAGCCGGCGAAGAAGAGGAAGAGGAGGATAAGGATACGGAGATGGCAGATGGCACCAAACCCAAGCCTACGACCAAGTTTCGCAACAAGCACGTGCGCCCACACTTCACCTGCAACTTCTGCAATTACACTAGTCATCGCCGGTATCTCCTCCTACGTCACATGAAGTCCCACTCAGAGGACAGGCCACACAAGTGCAACGTGTGCGAGCGCGGCTTCAAGACGCTGGCGTCACTTCAGAACCACGTGAACATGCACAACGGCATCAAGCCGCACGTCTGCAAGTACTGCAACAGCCCCTTCACTACCTCGGGTGAGCTGGTGCGTCACGTGCGCTACAAGCACACGCACGAGAAGCCGCACAAGTGCTCGGAGTGCGACTACGCTTCCGTGGAGTTGTCCAAGTTGCGCCGCCATGTGCGCTGCCACACCGGCGAGAGGCCCTACCAGTGCCCACACTGTACATACGCGTCGCCGGACACGTTCAAGCTGAAGCGCCATCTGCGCACTCACACAGGCGAGAAGCCCTACAAGTGCGAGCACTGCAACATGTGCTTCACGCAGTCCAACTCTCTGAAAGCCCACCGGCTCATTCACAACGTATCCGAAAAGCCAGTGTACTCTTGCGAGCTGTGCCCGGCCAAGTGCGGCCGCAAGACGGACCTGCGCATCCACGTTCAGAAGCTGCACACGTCCGACAAGCCGCTCAAGTGCCGCCGCTGCGGCAAGTCCTTCCCAGATCGCTACTCCTGCAAGGTGCACAATAAGaCCCACGAGGGCGAGAAATGCTTCAAGTGCGACCTGTGCCCGTACGCGTCGACCACGCAGCGCCACCTCAAGACGCACATGCTCAAGCACACGGACGAAAAACCGTTCATCTGCGACATGTGCGACCAGTCCTTCAGGCAAAAGCAGTTGCTCCGTCGTCACCAGAACCTGTACCACAATCCCAACTACGTGGCGAAGCCGCCCAAGGAGAAGACGCACTCGTGCCACGAGTGCCAGCGCATGTTCGCGCACAAGGGAAACCTTATCCGACATCTGGCCGTGCACGACCCGGAGTCCGGCCATCACGAGCGCGCGCTCGCTCTCAAGATTGGACGACAGAGGAAGGTCCGTTTCGTCGATGGAGAACCTATGAGGGATAATATCCGCGTCCTGGACCCATCGGACACCGAGAGCATGGTGAAACTCGGTCTCAGCAACAACGAGCTGAAGCGCGGCGAGTTCGTGACCGTGGCCGACGGCGAGGGCCACCAGTATGTGGTGCTCGAGGTCATCCAACTCGAAGACGGCACCGAACAGCAGGTGGCCGTCGTGGCACCCGAGTTCATTGAAGAGGATGAGGCTGAAGAGGAAGAGGAAGAGGAGGAAGAagaggaagaagaagaagaggagGAGGAAGATGAGGGGAAGGTCAGGGATTTTGTCATAAAGGGCAGCACTGTCTCCACACAGAGCATTAAACTTGAAAAGGAGGTTGACACATGCTTTGGATTTGATGAGGAAGAGGAAGAGCCCGATGATGATATTGATGTCGATGTCGACGTCGATGTCAACTATACAGACAAAGTGGTATTGCGTTTAGTTTAG
Protein Sequence: MPPPIKKEKNKPALIQTYQGAVITVNAATDDKSLPTGMVEYFVDEDGKYYYQSAVGGQTLVMNTEGNQEDEEVAETSDPMLTEQGETYQTVAFLPTENNGEVSYVLVVQEENKGGVVNMELKVDQGRENVKTEAEEKANDDVYNFDEEEAGEEEEEEDKDTEMADGTKPKPTTKFRNKHVRPHFTCNFCNYTSHRRYLLLRHMKSHSEDRPHKCNVCERGFKTLASLQNHVNMHNGIKPHVCKYCNSPFTTSGELVRHVRYKHTHEKPHKCSECDYASVELSKLRRHVRCHTGERPYQCPHCTYASPDTFKLKRHLRTHTGEKPYKCEHCNMCFTQSNSLKAHRLIHNVSEKPVYSCELCPAKCGRKTDLRIHVQKLHTSDKPLKCRRCGKSFPDRYSCKVHNKTHEGEKCFKCDLCPYASTTQRHLKTHMLKHTDEKPFICDMCDQSFRQKQLLRRHQNLYHNPNYVAKPPKEKTHSCHECQRMFAHKGNLIRHLAVHDPESGHHERALALKIGRQRKVRFVDGEPMRDNIRVLDPSDTESMVKLGLSNNELKRGEFVTVADGEGHQYVVLEVIQLEDGTEQQVAVVAPEFIEEDEAEEEEEEEEEEEEEEEEEEDEGKVRDFVIKGSTVSTQSIKLEKEVDTCFGFDEEEEEPDDDIDVDVDVDVNYTDKVVLRLV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00301464;
90% Identity: iTF_01062117;
80% Identity: -