Basic Information

Insect: Nymphalis polychloros
Gene Symbol: FTZ-F1
Assembly: GCA_905220585.1
Location: HG992241.1:11260654-11275008[+]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 2 4.5e-17 5.8e-13 49.5 6.7 1 41 117 156 117 162 0.90

2 2 5e-75 6.4e-71 240.4 0.4 79 408 175 489 167 491 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	2	4.5e-17	5.8e-13	49.5	6.7	1	41	117	156	117	162	0.90
2	2	5e-75	6.4e-71	240.4	0.4	79	408	175	489	167	491	0.89

Sequence Information

Coding Sequence: ATGTCAGATGGCACAATTCTCACAAATCGCTTACTGACCTCAATCGCGGTTGTTGCGAGAGGCTCGCAGTGCCTGCTCGACCTGCAACGAGCCTTGTGCAATGCCAACGCGCAGCCGCTCGCCCGCGCCCGCGCCCGCTACTCCGTCCGCAACTTGTCACTGACTACAGCTACTGCTGTTAAAAATGTTGAGCTCCAACTTGTTCAAGTAGAAATGCGCGCGATCAGAGTACGTACGGGCGCGGGCGGTCGGGCGGGCTCGGCTCGCTTCGGAGCGACCGCACCGAACGACGCGGTGCGGCGGGGGACGCCTACAGCCTTGACCAAGTTTCACCGGCTCGTCGCCGTCGCCGTACGAGCGGATCGCATGCGAGGTGGTCGCAATAAGTTCGGCCCCATGTACAAACGCGATCGTGCCCGCAAATTACAAATGATGAGACAAAGGCAAATAGCAGTGCAGACACTACGTGGCTCTCTCGGAGAGGGTGGGCTTGTACTTGGATTCAGCTCGCCGTATGCCACTGTGCCTGTAAAGCAAGAAATTCAGATACCCCAAGTTTCGTCGTTGACGTCATCACCGGAATCTTCGCCGGGTCCAGCGTTGTTGGCTGCACAATCCCAGGCGCCCCAGCCACCGCCTCCCCCGGCTCACGACAAGTGGGAAACTCACTCGCCGCATTCAGCGTCACCGGACGCGTTCGCCTTTGAAACGCCCGCGACCACCACACCCTCCAGCACCGCCGAAGCTACCAGCACCGAAACTCTTCGAGTTTCACCCATGATTCGCGAATTTGTTCAAACCATAGATGATCGAGAGTGGCAAAACTCCCTTTTCGGACTCTTGCAGAGCCAAACTTACAACCAGTGTGAAGTCGATCTCTTCGAATTAATGTGCAAAGTGCTGGACCAAAACTTGTTCTCTCAAGTGGATTGGGCGAGAAACACCGTGTTCTTTAAGTATTTAAAGGTCGATGACCAAATGAAGCTGCTGCAGCACTCGTGGTCGGACATGCTGGTGCTGGATCACCTACACCAGAGGATGCATAACGGGTTGCCCGACGAGACCACCCTTCACAACGGCCAGAAGTTTGATCTACTCTGCCTGGGTCTCCTCGGTGTCCCCTCACTCGCCGAGCACTTCAACGAGCTGCAGAACAAACTCGCCGAATTGAAGTTTGACGTACCGGACTACATCTGCGTTAAATTTTTGCTTTTACTTAATCCTGAAGTGAGAGGCATTGTCAACGTTAAATGCGTCCGAGATGGCTACCAGACAGTTCAAGCCGCTCTTCTCGACTACACGCTTACCTGCTATCCGACGATACAGGATAAATTTGGAAAATTGGTGATGGTGGTCCCAGAGATACACGCGCTGGCGGCCCGGGGGGAGGAACACCTGTACCAGCGGCACTGCGCCGGCCAGGCGCCCACACAGACGCTTCTCATGGAAATGCTACACGCTAAGCGCAAGCCCAATGGAGCCGAAATGGTAAACCGGAGTGCGGATCACACCTCGACTCTAGACAGATTGTGCGGTTTCCTGCCGAACGACACGATTGAGCCGCATTCCCCCATATAG
Protein Sequence: MSDGTILTNRLLTSIAVVARGSQCLLDLQRALCNANAQPLARARARYSVRNLSLTTATAVKNVELQLVQVEMRAIRVRTGAGGRAGSARFGATAPNDAVRRGTPTALTKFHRLVAVAVRADRMRGGRNKFGPMYKRDRARKLQMMRQRQIAVQTLRGSLGEGGLVLGFSSPYATVPVKQEIQIPQVSSLTSSPESSPGPALLAAQSQAPQPPPPPAHDKWETHSPHSASPDAFAFETPATTTPSSTAEATSTETLRVSPMIREFVQTIDDREWQNSLFGLLQSQTYNQCEVDLFELMCKVLDQNLFSQVDWARNTVFFKYLKVDDQMKLLQHSWSDMLVLDHLHQRMHNGLPDETTLHNGQKFDLLCLGLLGVPSLAEHFNELQNKLAELKFDVPDYICVKFLLLLNPEVRGIVNVKCVRDGYQTVQAALLDYTLTCYPTIQDKFGKLVMVVPEIHALAARGEEHLYQRHCAGQAPTQTLLMEMLHAKRKPNGAEMVNRSADHTSTLDRLCGFLPNDTIEPHSPI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00364088;
90% Identity: iTF_01079993;
80% Identity: iTF_01079993;