Basic Information

Insect: Nymphalis io
Gene Symbol: egg
Assembly: GCA_905147045.1
Location: LR989922.1:1837271-1867731[-]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 8.9e-13 5.7e-09 36.0 0.0 4 75 1544 1608 1541 1610 0.88

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	8.9e-13	5.7e-09	36.0	0.0	4	75	1544	1608	1541	1610	0.88

Sequence Information

Coding Sequence: ATGGATTCAACAGAAAACACAGAAGTCAGTGATAAGGATGATGGGGAGATGGCTTCTATTCAATTAATAGAAAAAGAAACAATAAATTCGAGTGACGTAGATGAATTAAACACGACTGTTTTAAACGAAGAATTAATTACAAAAGGTACTGTGAAGGATGATGAAAACACACGTTCATCAATCGAAAAAAATGTTGAAGAAATATTGCTTGGTGATGGTAATACTCAGAATCTAGACAGTGATAATGTTGATGAAGAAATGGAGCTGAGATGGGATGATGATGAACTTGACGAAGTTGATGAAATAAGGAATGAGGCGACTTTGCTTGAGGAAGATTTGTTAGATTCCCCCAAACCTTGTACTTTATCACTGCAAGATGAAGTTATTAAAACTATAGAAGCTGAAGAGAACCTTCTAAACTTAGATAACGATAATGAATCCAAAGAATCACCCCCAGATTCTATAAAAGAGAGATTGTTCGCACCTAACAATGATCACAATTTAAATAAACCCGATATTATGTTAGAAATTCCAAGTCATGAAGTAATTGAATTTAGTGATGATGAAGAGGATTTGATTAACAATCTTGAAATGTCTCCTGACTTAGAAAGCGATGAAGAAATGTGTAATTCAACTGAAGTTCCAATTGAGTCAACCCAAGCTGATGTACATGCTGATGATGAACAAGGAGAAGGTGATGTACTAGAAGTAGAAAAAGATTTAACCAATATAGAACCAATTGAAACAATGAATAAAGCACTCGAAAATGAAGCTAAATTTGCAGCAGATATTCTCACAAAAGAGCTTAATGTAATGCATTCAGTACCAATTATTACCACAGACACAAATACAGAAATGAATGAAGAATTTCTTTTAAAAGAAGACTCAATGCAAGATGATTGCCTTTTAAAAGATGGCACAATTGAAGATGATTGTCTTTTAGAAGAATATACAACAATCCAAGAAGGAATAATAGAAAATGTAAATAGTTTAAATGGTGAATCAGATATAATTAAACTAAAAGACCCGACAGAGGAATCACTTAAGAAACAAGATAATTTAGATGCAACAAATACAATTGCTAATGAATCAGAACCACGAGAGGATACACAAAGCGTTGATGAAGAAATGACTGATTTGTATGAGGACATATTACTAGCGACTAGTGATAATTCTACAGATGCTAAAGAATCTGTTCCTGATTTAGAAGATACAACAATTTTAAAATCAGAATCATCCATTGATGTGGCAATTAATATAAAAGAAACAGACACACCAAAAACTGAATTCCACACAAGTGTAACTGAAGATAAAATGACAGATACAATTGAAAATGATTCTTCTTCGGAAGCAAATATTGTGACTGAATCTCTAGACGCTGATATTACGATAATATCTAGTAATGAAGATAATGAAACAGACACAGATTTCATTGATACCATCCCAACAATTCAACAATCAGAAAAGGAAGAAGAAAGCATATTAGATAAGCTAATCACTAATACAGCGAAAAAAAATACTGACGTTCAAGCGTCTACTTCAACTGCTTATATAGACACACACAAAGAAGAGATCCCTTCAAACACAGATATAAAAGAAATTACTAATGATGAAGTACCCAAGGACTTACAATCAGGATTGTCAAGACAAGACGAACACACACTTGAATATCCACTGTCTACATCTACTCTAGATTTAAAGGGAGATGAAGCCAAATCACTTGTGTCATCGGTTTATGAAAAAACCTTTGCAAATGTGTCTATTGATTTGCATCTACCAGCACACCCAATGGATATTGATCAACCGCAACCATCGACATCATTTGCTTGTCTTAAAACATCAAAAAGCCCAGATGAACAATCATCAATGTTTGGCTCATCAATGGTTAAAGATAAAGATGTACCGGAAATGACAGACAGTCTCGGTCTCCTGGCTGAGTGTAAAATGATGGAGGAAGATGAGGAACAGGAATATGACGATGACGGTGATGGGGAAGATGAAGATGATTTTGACCAAGATGATGAGAGCAGCAACCAAATGACCGCAGAACATTCCGAAGACTCAAACGCTCAGCATTCAGAGTCCGAAGTGCAAAAAGAAATGCAAATTGACTTTCAAATTGATAATGTGGTTTCTGAGGATGCAGAAACTGAAAATAAGGAATATACTGATACTAAACCGGAGCAGCAAGAAACAACTGGAAAAGATGTTGAAATCAAATTACAGAATGACGACAACAAATCAAACATCGAAACGGTGAAGCTGTCAGACACGTCAGATACAGAAATAGACTCGGAAACAATAGAGACAAATATACTAAAAACATTATTATTGACAAAAAATGATACATTAATGTCGGATAAGGTTGTTGAAGAGAAACAATCACCGAGCAAGTCTAAAAATTTGGAAATAGTTAAACAAGATACGATATTGAGTTTTGTTGACCTCGAAGAGAGCTCCTCGGAAGACGATATGAAAGAGGTGAAGGATGAATCTTCAAAAGTTATCCATGAAGACGAAAACGCAACAAAAGTTGATGAATCCGACAACACAAGTGCTGCTACAAAAGTGAAAAGTGAAGCTCTCGACAGCACACTGAAAACGTCACCAACTAAATCTGTAACACAAGATACGAAAACAGCGGATGGATCAACCGACGTCATTGAAGAAAGCAAGCCGAAAGTTTCGATAGGCTTGGAAGTCTTCAACCTCGATTCTGATGATGAAGAAGAAAATGTACCCGAAGAAGCATCTCAGGATATCCCACATGTACAGACTCAGGATGTGAAAGACGAAATGACGAGCGAGCCACTCAAATGCATCAACAGGTGTTGCCCGGGCGACAGTGGCGTTGAATTCTATATAGCCGACAGCGAGGCGATAAACTTCTATGATGCGGACAGGAAGAGGCGCGGCTACGTGTGCCAGAACTGCGCTGATGCCGTGGAGAAACGGAACCAGGAACTAATAGACGGTATCAAGAATTTCACACCGCTCCTGGAACTTGGTATCAACAAAAGCGGTGAGGAGCTGGTCGAGATATCAGACTCCGAGTCCGAGGATGAACCGGAACTAGACCAGGATCAGATGCAAATAATCGGGGTAGAAGGCGCGAAAAAAGCGGAGGAGAATCTAGCGTCGTTGATAAATGAAACGTGGGAGAAATACAAAATGGACGCGCGTTTGGCGGACACGCAGGACGCGTTGGAAAAAGAAATAGAAAAATTGCAAAAGGAAAGCGAGGAAATCAACGAAATTTTAAACGAATGCCAGGTGGCGACGGACCAGCTGAGGAACGAGCTGTACGCGACCTTCGAGCCGGACATACGGGAACTATCGCCGTTTGTTATATACGACATGCCGAACTGCTCGTATTCGTGCATCGAACCTCCAACGACCGAGCATGTTACAATGAAACGAACTCGGTCACCGACCAACGAGATTCCAGCCAAACGTCCCGCTATACCGTTGGGGTATGCGCCGTTAAATGAAAAAAATAAAGAGGATTCGAAGAATATGATAGTGACGAGCGAAAAAGCTGAAGATGATAATACGGATGTGTCAGTCGTAAAGTTGTCAGCGGAATCAGCCCCGAAGGATCTGCCGCCGCCAGGGGAAATCACGATGCCTCCCGTCAAGGCCGGGATGACGGTGTATGCGATGAAGAACGCCTTCGGTTCCTGGCTCAAAGCGAAGATTGTTGACATATTACCGAAGCCACCTAATTCAACATTCACACTGTGTCGTGTTAAATTTGAACACAAAGTGACGAAGAACATGTACAAGATACTCCCGGCGAGGTGCCTGGCGTACTACGAGCCCCCTGACGTCAGGATGACCATTGGTCGTCGTGTCATAGCGCTCTTCAAGGATACAAATAAACGCGAGACATACTATTCCGGAGTCGTAGCTGAGATACCGAATCCGGTTAATTCTTATCGCTACTTGATCTTCTTCGACGACGGCTACGCGCAGTACGCCCAGCACGCACAGACGCGCCTCGTGTGCGAGTGCTCGTGCTTCGTGTGGGAGGAGGTGCACCCCTACTCGCGCGACTTCGTGCGCCAGTACCTGTTCGCCTACCCCGAGCGGCCCATGGTGCGCCTGCACGCCGGGCAGAAACTCAAGACCGAGTGGCGAGGCAAGTGGTGGTCGTCCAGCGTGGTGCGCGTGGACGCGTCGCTGGTGGAGGTGCAGTTCCTGCGCCGCGACCGCCGCGAGTGGATCTACCGCGGGTCCACCCGCCTCGCCCCGCTGTACCTGGAGCTGCAGGCGGCCGAGCGGCACCGCCCCCGCGCCGTGCCGCGCGCGCAGCCGCAGGCCAGGATGAACATGCCGTATGTCGAATATACGAGATCGGATGAACAGACCAACAAAGCGGGCGACGCGCAGACCCAACTGCAGCGAGCACAGATACAAAACGAGGAGCTGCGGCGCCAGCGCGCGGTGGCGAAGAAGTCCACGGCCGCGCCCGCGCCGCCGCCCGCCGGGGCCAACCTGGACAGCGTCGCCAGCAGGGTGGTCTTTTACACGCCGAAGAGTGCGGTTAAACCGTACAAAATGGTACCACATACGTGTTCGCCGAAATGCAAGAGAACAGACGTTCTGGATCTCAAAGATCTTCGAACGTACAACCCGCTGACCAAACCGTTACTGAGCGGTTGGGAGAGACAGGTGGTGCGCTGGAAGGGGGGCCGCAGCGTGCTGTACGTGGCGCCGTGCGGGCGCCGCACGCGCGACGTGCGCGAGCTGCACGCGTACCTGCGCGCCGTGCGCTCCGACATGGCCGTCGACCTGTTCGACTTCAGCCCCAGCACGCACTGCCTGGCCGAGTTCGTGCTCAACAGCTGCTTCGTCGGCAAGAAGGACCTGTCGCACGGCAAGGAGAACGTGCCGGTGCCGTGCGTGAACTACTACGACGACTCGCTGCCGGAGTTCTGCTCGTACAACACGGAGCGGACGCCGACGGCGGGCGTGCCGCTCAACCTCGACCCGGACTTCCTGTGCGGCTGCGACTGCGACGACGACTGCGAGGATAAAACGAAGTGCGCCTGCTGGAAGATGACTCTAGAAGGTGCTAGAACGATTGGCCTGGAAGGCGATAACGTCGGCTACGTGTACAAGAGGCTGCCGGAGCCCTTGCCTTCGGGCATTTATGAATGTAATTCCAGATGTAAATGTAAACACACGTGTCTCAATCGCGTCGCGCAGCATCCTCTACAGCTTAAGTTACAGGTATTCAAAACTCTGAACCGAGGTTGGGGTATAAGGACCCTCAATGACGTCCCCAAGGGGTCCTTCCTCTGTGTGTACGCGGGTAACTTGCTCACAGATGCGACAGCTAACTTGGACGGTCTCAACGAGGGGGACGAGTACCTGGCTGAGTTGGACTACATCGAGGTCGTGGAGCAGATGAAAGAGGGCTACGAGGAGGATATACCGGAGCATATCAAAAAGTTAGACAAGAAGGAACTTGAATCGAAAGCGTCAGAGGAAACGGAAGAGGAGGAACAGTCATCAGATGAAGAGATGAGTAACAACAAGACGGACCTTGAGGATGATGACTTCGAGCCGGGACATATAGGTCTCGGCCTGGCTGAGTTCAATAAACGTTTACGGAAAAGGGAGTCGAAGAAAGAGAAAAATAATGAAAAAATAAAAGAGGAAGAGAATCAAAAGGAAGTCGATAAAAAGGAAATAAAGGAAGAAACAAATCCAGATGAGGACTGCATCACCATCAGTGATGACGAAGAAGTGAGGGAGCCGTCATGTTTCACGGCGGCCGCCGGTATGGGTGCCAACGAATTTATATCTAAATACAGATCAGTACGGAGGCTGTTCGGAGAAGATGAAGCGTGTTACATCATGGACGCGAAGGTTCAGGGCAATATTGGGAGATATCTAAATCACTCGTGCTCGCCGAACGTGTTCGTGCAGAACGTGTTCGTGGACACCCACGACCCGCGGTTCCCGTGGGTGGCGTTCTTCGCGCTGAGCCACATCAAGGCGGGCACGGAGCTCACGTGGAACTACAACTACGACGTGGGCTCCGTGCCCGGCAAGGTGCTGTACTGCCACTGCGGGGCCAGCAACTGTAGGGGGCGGCTGCTCTAA
Protein Sequence: MDSTENTEVSDKDDGEMASIQLIEKETINSSDVDELNTTVLNEELITKGTVKDDENTRSSIEKNVEEILLGDGNTQNLDSDNVDEEMELRWDDDELDEVDEIRNEATLLEEDLLDSPKPCTLSLQDEVIKTIEAEENLLNLDNDNESKESPPDSIKERLFAPNNDHNLNKPDIMLEIPSHEVIEFSDDEEDLINNLEMSPDLESDEEMCNSTEVPIESTQADVHADDEQGEGDVLEVEKDLTNIEPIETMNKALENEAKFAADILTKELNVMHSVPIITTDTNTEMNEEFLLKEDSMQDDCLLKDGTIEDDCLLEEYTTIQEGIIENVNSLNGESDIIKLKDPTEESLKKQDNLDATNTIANESEPREDTQSVDEEMTDLYEDILLATSDNSTDAKESVPDLEDTTILKSESSIDVAINIKETDTPKTEFHTSVTEDKMTDTIENDSSSEANIVTESLDADITIISSNEDNETDTDFIDTIPTIQQSEKEEESILDKLITNTAKKNTDVQASTSTAYIDTHKEEIPSNTDIKEITNDEVPKDLQSGLSRQDEHTLEYPLSTSTLDLKGDEAKSLVSSVYEKTFANVSIDLHLPAHPMDIDQPQPSTSFACLKTSKSPDEQSSMFGSSMVKDKDVPEMTDSLGLLAECKMMEEDEEQEYDDDGDGEDEDDFDQDDESSNQMTAEHSEDSNAQHSESEVQKEMQIDFQIDNVVSEDAETENKEYTDTKPEQQETTGKDVEIKLQNDDNKSNIETVKLSDTSDTEIDSETIETNILKTLLLTKNDTLMSDKVVEEKQSPSKSKNLEIVKQDTILSFVDLEESSSEDDMKEVKDESSKVIHEDENATKVDESDNTSAATKVKSEALDSTLKTSPTKSVTQDTKTADGSTDVIEESKPKVSIGLEVFNLDSDDEEENVPEEASQDIPHVQTQDVKDEMTSEPLKCINRCCPGDSGVEFYIADSEAINFYDADRKRRGYVCQNCADAVEKRNQELIDGIKNFTPLLELGINKSGEELVEISDSESEDEPELDQDQMQIIGVEGAKKAEENLASLINETWEKYKMDARLADTQDALEKEIEKLQKESEEINEILNECQVATDQLRNELYATFEPDIRELSPFVIYDMPNCSYSCIEPPTTEHVTMKRTRSPTNEIPAKRPAIPLGYAPLNEKNKEDSKNMIVTSEKAEDDNTDVSVVKLSAESAPKDLPPPGEITMPPVKAGMTVYAMKNAFGSWLKAKIVDILPKPPNSTFTLCRVKFEHKVTKNMYKILPARCLAYYEPPDVRMTIGRRVIALFKDTNKRETYYSGVVAEIPNPVNSYRYLIFFDDGYAQYAQHAQTRLVCECSCFVWEEVHPYSRDFVRQYLFAYPERPMVRLHAGQKLKTEWRGKWWSSSVVRVDASLVEVQFLRRDRREWIYRGSTRLAPLYLELQAAERHRPRAVPRAQPQARMNMPYVEYTRSDEQTNKAGDAQTQLQRAQIQNEELRRQRAVAKKSTAAPAPPPAGANLDSVASRVVFYTPKSAVKPYKMVPHTCSPKCKRTDVLDLKDLRTYNPLTKPLLSGWERQVVRWKGGRSVLYVAPCGRRTRDVRELHAYLRAVRSDMAVDLFDFSPSTHCLAEFVLNSCFVGKKDLSHGKENVPVPCVNYYDDSLPEFCSYNTERTPTAGVPLNLDPDFLCGCDCDDDCEDKTKCACWKMTLEGARTIGLEGDNVGYVYKRLPEPLPSGIYECNSRCKCKHTCLNRVAQHPLQLKLQVFKTLNRGWGIRTLNDVPKGSFLCVYAGNLLTDATANLDGLNEGDEYLAELDYIEVVEQMKEGYEEDIPEHIKKLDKKELESKASEETEEEEQSSDEEMSNNKTDLEDDDFEPGHIGLGLAEFNKRLRKRESKKEKNNEKIKEEENQKEVDKKEIKEETNPDEDCITISDDEEVREPSCFTAAAGMGANEFISKYRSVRRLFGEDEACYIMDAKVQGNIGRYLNHSCSPNVFVQNVFVDTHDPRFPWVAFFALSHIKAGTELTWNYNYDVGSVPGKVLYCHCGASNCRGRLL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01079916;
90% Identity: -
80% Identity: -