Basic Information

Insect: Notodonta dromedarius
Gene Symbol: Hr39
Assembly: GCA_905147325.1
Location: LR990163.1:2737119-2758994[-]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 4 0.022 2.3e+02 1.2 1.5 119 201 270 351 213 369 0.67

2 4 2.5e-08 0.00026 20.7 0.1 1 21 441 461 441 481 0.88

3 4 0.025 2.6e+02 1.0 0.0 80 113 489 523 469 535 0.64

4 4 7.3e-63 7.7e-59 200.4 0.0 203 408 562 768 548 768 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	4	0.022	2.3e+02	1.2	1.5	119	201	270	351	213	369	0.67
2	4	2.5e-08	0.00026	20.7	0.1	1	21	441	461	441	481	0.88
3	4	0.025	2.6e+02	1.0	0.0	80	113	489	523	469	535	0.64
4	4	7.3e-63	7.7e-59	200.4	0.0	203	408	562	768	548	768	0.94

Sequence Information

Coding Sequence: ATGAATACTGCGATGACAAGTGAAGGAGACGCGGTTAAGGTGGAGGGGGGACACGTGTCAGTCACAACCATCAGCATGTCGGGACCCGAAACCAGCAATGGTCAGTTCTTGTACAGTTCGAGCGGAGTCCGCATCAGTGTGTCTTCAGTGCCCCATGATGAAGACTCCACTGACGCTGAGATCTCCAAGATTGATTTCACGCAACATCAGTATGAGGTAATAGTTAATATGCGTAATAAGAAGAAGCGGTCATTGAGCGGCGCGCACTGCGACGCGAGCAATGAGCGCGAGAGACCCATGTCCTGGGAGGGGGAACTGTCAGACTCCGAGATGGTGATCGACACCAGTGTCAACAATGATGAGAACAGCAGTTCCCTGGACCTCCAGTCCTCTCGGGACTCCATCGACACGTTGCGCAATGTGACCATCAAGACCGAACCCCTTAAGAGTGATTACCAGAGCGTGGACGACGAGCGGGTCCTGGACTTGAAGTATAACACGCCGCTGCAGTCGCATCAGAGGAGCCTCAGCATGAATAGGATATCAGTGTTGACGGACAGCTCGTCGCTGTCGCTGGCGCGGCGGCCTGCGTCTCCTGGCGGCAGCGGGGGCGGCGGCGGGGGCTGCGGGCGGGCGCAGGAGCCGGCGCTGGAGCCGCCGCACGCGCTGGCCGAGGTGCAGAACCTCACCATCAAGAAGGAGACTCATCTGCCTGAGCTGAAGTGCGAGCAGGCGGTGGGCATGGAGAAGCTGCTGGGCGCGCTGCACGGCTCGCCGCTGCTGGGGCGGCTGCCGCGCGTGCAGTCTAGCGCCAGCACCGACTCCGCCGTGCACTCCATGTACACGCACAGTGTATACAGCAGTCCGTCGGCGAGCCCTCGCGCGTCGAGGCACTACACGCCATCTCTTTCTCGCAACAACAGCGACGCATCGCACTCTTCCTGTTACTCCTACAGCTCGGAGTTCTCACCCACACATTCACCAGTACAGGGGCGGCACCCGCACGTGGTGTACCGCGAGGCGGCGGCCGCGCACGACGACGAGCCCGAGCCCGCCGAGGACCGGCTGCACCACCACCAGGGGATCAGCAGGCAGCAGCTCATCAACAGCCCATGTCCAATCTGCGGCGATAAAATCAGCGGGTTCCACTACGGGATCTTCTCGTGCGAGTCGTGCAAGGGTTTCTTCAAGAGGACGGTGCAGAATCGGAAGAACTACATGTGCCTGCGCGGGGGCAGCTGCCCCGTCACCGTGGCCACCAGGAAGAAGTGCCCCGCCTGCCGCTTCGACAAGTGCCTGGGCTGCGGGATGAAGTTGGAAGCGATAAGAGAGGACAGAACACGCGGCGGCAGGTCGACCTACCAGTGCTCCTACACGCTGTCGGGCGCCGCGTCCACCGGCTCGCTGCTGTCTGCGCACGCGCCGGCCACGCTGCGCCACGCCTCCAGCCTCACATGCGTCAACGGTCCAGGATCGTACAGCAGTCGAGGGGAGTCCAGCAGTAGTCAAATGACACCAGATATACCGCCATTATTACAGGAAATAATGGACGTTGAGCATCTGTGGCAATACAACGAGTCGGAGCTGAGCCGGCTGGGGCGGGCGGGGGGCGGGGGCGGGGGAGGCGGGGGCGGGGGCGGGGGCGGCCCCAACCCGCTGCTGGCCGCCAGCGGCATCACCGCGCAGAACTCCAGCCCCGACTTCCTCGCCGACCTGTGCAACATAGCCGACCACAGACTGTACAAGATCGTCAAGTGGTGCAAGAGTCTGCCGCTCTTCAAGAATATCTCGATCGACGACCAGATCTGCCTGCTGATCAACAGCTGGTGCGAGCTGCTGGTGCTGTCGTGCTGCTACCGCGGCGTGGGCTCGCCCGGGGAGGTGCGCGTGGGCGGCGGCCGCGGCATCACGCTGCAGCACAGTGCCAAGTTGGGTTTGACGCCGTGCATAGAACGCATGCTGAGTTTCACGGACCACCTGAGGCGGCTGCGGGTCGACCGATACGAATACGTCGCTCTCAAGGTCATCGTACTACTCACATCAGACGCACCGGATCTGCGTGAAGTGGAGAAAGTGCGCGCATCGCAGGAGAAGGCGCTGGCCGCTTTACAAGCATACATAGCGACGCACTCGCCGGGCACGCCCGCTAAGTTCGGAGAGCTCCTGTTGCGCATACCGGAGCTGCAGCGGACTTGCCAGTTCTTCATGCAAGTTGGCAAAGAAATGCTGAACCCTGCGAACAAGAGCAAAGACGGTGACGGGCCAAGTTTCAACCTGCTCATGGAACTGCTAAGAGGTGACCACTGA
Protein Sequence: MNTAMTSEGDAVKVEGGHVSVTTISMSGPETSNGQFLYSSSGVRISVSSVPHDEDSTDAEISKIDFTQHQYEVIVNMRNKKKRSLSGAHCDASNERERPMSWEGELSDSEMVIDTSVNNDENSSSLDLQSSRDSIDTLRNVTIKTEPLKSDYQSVDDERVLDLKYNTPLQSHQRSLSMNRISVLTDSSSLSLARRPASPGGSGGGGGGCGRAQEPALEPPHALAEVQNLTIKKETHLPELKCEQAVGMEKLLGALHGSPLLGRLPRVQSSASTDSAVHSMYTHSVYSSPSASPRASRHYTPSLSRNNSDASHSSCYSYSSEFSPTHSPVQGRHPHVVYREAAAAHDDEPEPAEDRLHHHQGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYMCLRGGSCPVTVATRKKCPACRFDKCLGCGMKLEAIREDRTRGGRSTYQCSYTLSGAASTGSLLSAHAPATLRHASSLTCVNGPGSYSSRGESSSSQMTPDIPPLLQEIMDVEHLWQYNESELSRLGRAGGGGGGGGGGGGGGPNPLLAASGITAQNSSPDFLADLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLVLSCCYRGVGSPGEVRVGGGRGITLQHSAKLGLTPCIERMLSFTDHLRRLRVDRYEYVALKVIVLLTSDAPDLREVEKVRASQEKALAALQAYIATHSPGTPAKFGELLLRIPELQRTCQFFMQVGKEMLNPANKSKDGDGPSFNLLMELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01180394;
90% Identity: iTF_01073701; iTF_00622056; iTF_00622083;
80% Identity: iTF_01073701;