Ndro012109.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Notodonta dromedarius
Gene Symbol
egg
Assembly
GCA_905147325.1
Location
LR990189.1:3606416-3648562[+]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 2.6 1.1e+04 -3.6 0.1 29 38 1599 1608 1569 1609 0.66
2 2 3.7e-13 1.5e-09 37.5 0.0 4 73 1640 1702 1637 1706 0.87

Sequence Information

Coding Sequence
ATGAGTGCTACAACTCTAATGGAAGACGAATACAGTGTAAAGCAACCACAAGAAGCAGATATACCGGTGCAAGATGCCGCAACAATTTCAGAAGGTCAATCTGAACCATCTCTTCACAAAGCCATGGTGAAAGACGATGATAATGGCGGTAATCTTGAAATAACTCCATCTAAACAGCCTTTAGAAGAAGCTCTAGCTAATGTTGAAAATGCAGATGCTGTCAACAAAACTATGAGCCAAAGTTTACAACAACTGGCTAATGTTTCTACTGACATAAAACACTTAGATAGATCATCTGGAGATTTTCAAATTCAGGCTGAGAATACTATTACTATAGATAAAGACAATACGGCAACAGAAATAACTCCAGGTTTGATTGAAAATGAAGATAAATTAAATAAAAATGAAACTGTTGTATCAAAAATGGTGATGGAAGATGCTTCATCAGCAAAAGTCACTGAGGACAATAAAACTCATGTATCAATTACATTTATCGATAATAAATCTGTAAATGATAATGATATTACATCCCAGGATGTCTGTAATGATAATAATATAATCATTAAAAATACAGTTGAGCCATTATCTCAGTGTACCAAAGACATTGAAACTATTGATTCAGTGACATCCCAAACAAAAGATGATGAACCTGACTCAGATATGAGAATTGACAATGAAGATGATGAATTAGAATTAAAATGGGATGATGATAATGATGATGATTTAATGAAAGATGATATGGAATGTGATGCTGGTATTGAAGAGCAGGTTGAGACACTAGCAGATGAGTCTAGTATGGATATAGATTTGAACAACGATGAGGGGGATGTATTGAATGATAACCCTATAGTCAACAATGATAATGACAATAACGATGTTGAATCAAATAATGAAGAAACAATCCAGAATGCAGATAAAGAAACTGATGTCAATGTCCAAAATGATGAAAATACAAATGTTATTAATGAAAATGTAACTGAATCTGAATTAAATGCAGCAATAGCAAATGAAAATAAAGAAATGAATGTTCTGAATCATGAAATCTCATTAAGTCAAGATGTATCAATGGACAACTCGAGTGATCTCATCAATAAAGATCACGGTATCCACAGACCAGATGTTATGTTAGAAATACCAACACAAGAACTGATTGATATTGATGATACTGATCTATCCCTCAATCTGGATCAATCAAATGAAAGTCCAGAGCTAAATGAAATATTGACTGATAATAATGATATGCCAGTTAATGATAATAAAATAACAGACGATGAAGCAACATTCACTGTCAAAGATGTTGAATTAGGTATAACAGCTGATACTAAATTGCAAGAAAATGTAAAAGACTCAGTAGAAAATATAACTGAAAAAGTATTTGATAGTAACTCCCAAGATCAAATGCAACCATCAACATCATCTATTACTGACAAAATTACGATGGGCACGTCAGAAATGGCTAATGTGACTGACAGTCAGGGCAAATCAGGCTCCTCTGACGTTTTGGATGATGTGGCTAAGGTGTCAATAAGCTTCAATCCAGTAGTATTAGGAGAGGAGGACAAAGTTTCAGAAAGTGTCAGCCCAACTGCTCCAGAAAACAATATTACTGAAGACTCAATGAAAGCACCTGAAGTATTAGAAAGTGTCAATCCAGGTGTTACCACCTCAGTTGATATGTCTGAAGTCACTGAATATATGGACCCATTAGTGTCATCTACTATTAAGACTTCTGTTACACCTGACAAGGTTACTGCAGTGTCGGACAGTATCAATTTAATAGCCATCACCTCAAATAATAGTCCTGAAGTTACTGTAAATTCAGGTATGTCTATGTCATGTACTGAAATGTCACTAGAATCATCAGGAAAGGTCTCTGAGATGTCTGAAAGTATCAACCCGCAAGCTACAACATCAAGTGAGTTAACTAAAGTCACAGCCAATGTGGGCACATCAGAGGAATTGCCTCCAGTGTCAGACAGCATTGTTCCTGGACCTTCCACATCAAGTGAATTGCCCCCTGTTGCTGACAATTTGGAAAGCAGTAATCAGATGACGACAGCAGAACATTCCGAAGATTCAAACGCGCACCAATCAGAATCGGAGGTGAATAGAGACGAGAAAGAGACAGACATATCTCCCCCTGTGGAGAGCGAAGGAGAGTTCCAATTCATGATCAGTAATGTTGAGAGTCAAGGTGATGAAACAAAGGATATGGAGAGTATTGAGGTACCTGTTGAACAGCCGGTTAGCAATGAGGACAAAATTGAAGATATTGCAGAAGCTGTTGAAGCCATTGAACCCCTGGATGAGACACAGCGAGTGGATGACGATCAGACGCGCATAGAGACAGTCAGACTGTCAGACACCTCTGACAACGAGGTGGACGCTGAGTCAGGGGAACAGACACGCGAGCAGACAGACGCGAAGATAGCCCAGGAGAACGCAACATCAAGTGATCAGAGCAAGCTGTCTCCGAGCAAGACCAAGAAACTGGAGTTGTCGTCGACCGACCAGCCCGTGTTCAACATTGTGGACCTCGAGGAGAGCTCTTCGGAGGACGACGTTCAAGAAATACACAAAGAACCGGATACAGTGCCGGAAGTCGCCAGCACAGATGGCGTGACGAGCGTCAATCTGCCCAATGACATCGAGGTGATGTGCACATCCGCCGGAAACACGTCCGAGATCGTTACCAAAGAGGGAGAGGTGGTAATCAATGGGGTGCCGAAACCATCCCCCGTTAAAACTGCGAGACTGAATACCAGTGAAGTGTCCATAAAAACAGCTGGCACTCTCACGGAATCGACACTAGTTATACCAGAGGCGAAGACAACGCAAAAGACATCAACAGAAACTAGGGTGAAGCCCAAATTGTGCCTGGAAATATTCAGTCTAGATTCAGACGAAGAAGATACAAGTACGCCTGCTAAAGAGCAACAAAAGGCTCCGTGCGAGCCGGAGCCGGCGGCGGGCAGGTGCATGAACCCGGGGTGCCGCAGCGCGCTGCCCGCGCCCCCCGCGCCCCCCGCGCCGCCCGCGCCCCCCGCGCCCCCCGCGCCCCCCGCGCCGCCCGCGCCCCCCGCGCCCCCCGCGCCGCGCGCCCGCGCCGCCCGCGCGCAGCTCTGCCATCCCTGCGCCGCCGCGCTGCATCACGCCAAGCAGAATCTAATAACTGGTATAAAAGATCTCCGTCCGCTGCTGGAGCTGGGCGCGGACAAGATGTCCCAGGACCTGGTGGAGATCTCGGACTCGGAGTCCGAGGACGAGGCGGACGAGCCGAAGCCGCCGAGCGACACCATCGGGGAGAAGGGAGCCCAGATGCTTGAAGAGAATCTCGCCGCTATTTTCAACGAGACATGGCGCAAATATAAACTGGACGCGAGACTGAAAGATACCCACGACATATTGGATGCGGAACTGTTGAAATTGGAAAACGAGAGCAAAGAGATAGATGACATGTTGAACGAGTGCCAGGTGGCGACGGACCAGCTCCGCAACGAGCTGTACGCCACGTTCGAGCGCGGCTCCCGCGAGCTGCCGCCCTTCCTCATCTACGACACGCCCATGACCAGCTACATTGGTCCGGAGGTTGAGAAGACGGTTCTGCCGCCGCAACAAGAAACGTTGCGTCAAAGTAAAAGGCGTTTGCACACCGCGGCGGAGAGCCCCGCCAAGAAACCAGCTATACCGCTTGGATACACATCGCTGGACACAGATACAGCACAACAGAATATACAGGACTCCAAAACAGCTTTGTCTGATGGTGATAACAAAATAGATGATGATACGGAGGTGTCTGTGGTGCGGCTGTCGGCGGAGGCGGCGCCGGCCGACCTGCCGCCGGCGGGGGCGGGGGCGGGGGGCGGCGCGGCCGGGGGGGCGGGGGGGCCGGCGCGCCCCCCCCTGCGCGCCGGCGCCGCCGTGTTCGCCATGCGCAACGCGTTCGGGCCCTGGCTGCGCGGCAAGATACTCGAGTGTTTGCCCAAAACGAACTTGTCATCGCCGTATACAACGTGTCGTGTCAAATTCGACCATAAAGTCAAGAATCCGTGCAAGAACCTGACCGCGCGGTGCCTCGCTTACCCCGAGCCGGCTGAGTTCAGGATGACTATCGGTACTAGGATAATAGCGCTATACAAGGACCCTGGCAATGTTAAGAGGGAACAATTCTTCTCGGGCGTCGTCGCCGAGATACCCAACCCTGTCAATAGCTACAGATACCTGGTGTTCTTCGACGACGGGTACGCGCAGTACGTGCAGCACTCGCTCACCCGCCTGGTCTGCGAGAGCTCCTCCCTGGTGTGGGAGGAGGTCCACCCCTTCTCCAGACAGTTCGTGAAGGACTACCTGATGTCGTACCCCGAGCGCCCCATGGTGCGGCTGCACGAGGGCCAGAGCCTCAAGACTGAGTGGAACGGTAAGTGGTGGTCGTCGCGCGTGCTGGTGGTGGACGCGTCGCTGGCGCAAGTGCTGTTCCTAGAGGACGGCCGCAAGGAGTGGGTCTACCGCGGGTCCACCCGCCTGGCACCACTATACCTCGAGTTCCAGGCAGCCGGCAGGCATAGACAACGGCCTATGCCCAGGAGCAAGGCGGCTACTGGGAGCAACATGCCCTACGTGGAATACACACGCTCGGACGAGCAGGACAGCAACAAGCAACAGAACATGCAGACGCAACAGCAACAGAATGAGGAGTTGCGTCGGCAGCGCGCCGTGGCCCGCAAGTCCACGGCGGCGCCGCCCCCCTCCCCCGCCCCCGCCCCCGCGCCCCCCGCCCCACACAACCTGGACACCGTCACCAGCAGGGTCGTGTACTACACGCCGAAAGCGGCCGTCAAGCCGTACAAGATGGTCCCGCACGGCTGCGGCCCCCGCTGCCGGCGGAGCGACGTGCTGGCCCTGAAGGAGCTCAGGACCTACAACCCGCTGGCGAAGCCGTTGCTCAGCGGCTGGGAGAGACAAATAGTGCGTTACAAAGGGCATAAAGAGGTGATGTATCGCGCCCCTTGCGGCCGCCGCATCAGGGATATGGGGGAACTGCATCGGTACTTGAGAATAACCCAGAGCGAGCTGCCGGTGGACCTCTTCGACTTCTTCCACGGAACCCACTGCCTCGCCGAGTTCGTGCTCAACAAGTGCCTCGTGGGGAAGAAGGACCTCTCTCATGGCAAGGAGAACGTGCCGGTGCCGTGCGTGAACTACTACGACGATTCGTTGCCCGAGTTCTGTTCGTACAATACGGAGCGGACGCCCACTGCTGGGGTGCCACTTAACTTAGACCCTGACTTCCTGTGCGGGTGCGATTGCACCGACGACTGTATGGACAAATCCAAGTGTGCTTGCTGGCGGATGACGTTAGAGGGCGCTCACACCATCGGTCTAGAGGGTCCCAACGTGGGGTATGTCTACAAGAGGCTTCCGGAACCTCTGCCCTCAGGGATATACGAATGCAATTCGAGATGTAAATGCAAGGCGACATGTCTGAATCGAGTAGCCCAACACCCTTTGCAGTTAAAATTACAGGTATTCAAAACGCTGAACCGTGGTTGGGGCATACGCGCGTTGAACGACATACCCAAAGGTGCGTTCCTGTGCGTGTACGCGGGCAACCTGCTCACGGACGCCACGGCCAACTTGGACGGTTTGAACGAAGGTGACGAATATCTAGCAGAGCTGGATTACATAGAAGTGGTGGAACAGATGAAGGAGGGGTACGAGGAGGATATACCGGCCGCAGATAGGAAGATGGATAAGAGGGAGCTGGCGAAGCAGGAGGAGTCCTCGGAGGAGGAGTCCCCCTCGGAGGACGAGGGCCGCGCCGGGACCAGCGACAAGGAGGACGACGACTTCCAGCCCGGGTACATCGGGCTCGGGGTCATGGAGTTCAATAAAGCGTTGCGGAAACGGAACAAGACGAAGAAACATGATGAGGAGAAAGGGAAAAGCAAAGAGACAGAGAAGGAGCATACTAAGGATGATACCGAAGACTGCATCACCATCAGCGACGACGAGGAAGTGCGAGAGCCTTCCCGCTTCACCGCGCAAGCTGGCATGGGCGCCAACGCGTTCATATCGAAATACAGGTCGGTGCGTTCGCACTTCGGCAAGGACGAGGCTTGCTACATTATGGATGCTAAAGTACAAGGCAATATCGGAAGATACCTCAATCACTCGTGCACGCCCAACGTGTTCGTCCAGAACGTGTTCGTGGACACGCACGACCCTCGCTTCCCGTGGGTGGCGTTCTTCGCGCTCTCCCACATCCGCGCCGGCACCGAGCTCACCTGGAACTACAACTACGACGTCGGCTCCGTGCCGGGCAAGGTGCTCTACTGCTTCTGCGGCGCGCCCAACTGCAGGGGGCGCCTGCTGTAA
Protein Sequence
MSATTLMEDEYSVKQPQEADIPVQDAATISEGQSEPSLHKAMVKDDDNGGNLEITPSKQPLEEALANVENADAVNKTMSQSLQQLANVSTDIKHLDRSSGDFQIQAENTITIDKDNTATEITPGLIENEDKLNKNETVVSKMVMEDASSAKVTEDNKTHVSITFIDNKSVNDNDITSQDVCNDNNIIIKNTVEPLSQCTKDIETIDSVTSQTKDDEPDSDMRIDNEDDELELKWDDDNDDDLMKDDMECDAGIEEQVETLADESSMDIDLNNDEGDVLNDNPIVNNDNDNNDVESNNEETIQNADKETDVNVQNDENTNVINENVTESELNAAIANENKEMNVLNHEISLSQDVSMDNSSDLINKDHGIHRPDVMLEIPTQELIDIDDTDLSLNLDQSNESPELNEILTDNNDMPVNDNKITDDEATFTVKDVELGITADTKLQENVKDSVENITEKVFDSNSQDQMQPSTSSITDKITMGTSEMANVTDSQGKSGSSDVLDDVAKVSISFNPVVLGEEDKVSESVSPTAPENNITEDSMKAPEVLESVNPGVTTSVDMSEVTEYMDPLVSSTIKTSVTPDKVTAVSDSINLIAITSNNSPEVTVNSGMSMSCTEMSLESSGKVSEMSESINPQATTSSELTKVTANVGTSEELPPVSDSIVPGPSTSSELPPVADNLESSNQMTTAEHSEDSNAHQSESEVNRDEKETDISPPVESEGEFQFMISNVESQGDETKDMESIEVPVEQPVSNEDKIEDIAEAVEAIEPLDETQRVDDDQTRIETVRLSDTSDNEVDAESGEQTREQTDAKIAQENATSSDQSKLSPSKTKKLELSSTDQPVFNIVDLEESSSEDDVQEIHKEPDTVPEVASTDGVTSVNLPNDIEVMCTSAGNTSEIVTKEGEVVINGVPKPSPVKTARLNTSEVSIKTAGTLTESTLVIPEAKTTQKTSTETRVKPKLCLEIFSLDSDEEDTSTPAKEQQKAPCEPEPAAGRCMNPGCRSALPAPPAPPAPPAPPAPPAPPAPPAPPAPPAPRARAARAQLCHPCAAALHHAKQNLITGIKDLRPLLELGADKMSQDLVEISDSESEDEADEPKPPSDTIGEKGAQMLEENLAAIFNETWRKYKLDARLKDTHDILDAELLKLENESKEIDDMLNECQVATDQLRNELYATFERGSRELPPFLIYDTPMTSYIGPEVEKTVLPPQQETLRQSKRRLHTAAESPAKKPAIPLGYTSLDTDTAQQNIQDSKTALSDGDNKIDDDTEVSVVRLSAEAAPADLPPAGAGAGGGAAGGAGGPARPPLRAGAAVFAMRNAFGPWLRGKILECLPKTNLSSPYTTCRVKFDHKVKNPCKNLTARCLAYPEPAEFRMTIGTRIIALYKDPGNVKREQFFSGVVAEIPNPVNSYRYLVFFDDGYAQYVQHSLTRLVCESSSLVWEEVHPFSRQFVKDYLMSYPERPMVRLHEGQSLKTEWNGKWWSSRVLVVDASLAQVLFLEDGRKEWVYRGSTRLAPLYLEFQAAGRHRQRPMPRSKAATGSNMPYVEYTRSDEQDSNKQQNMQTQQQQNEELRRQRAVARKSTAAPPPSPAPAPAPPAPHNLDTVTSRVVYYTPKAAVKPYKMVPHGCGPRCRRSDVLALKELRTYNPLAKPLLSGWERQIVRYKGHKEVMYRAPCGRRIRDMGELHRYLRITQSELPVDLFDFFHGTHCLAEFVLNKCLVGKKDLSHGKENVPVPCVNYYDDSLPEFCSYNTERTPTAGVPLNLDPDFLCGCDCTDDCMDKSKCACWRMTLEGAHTIGLEGPNVGYVYKRLPEPLPSGIYECNSRCKCKATCLNRVAQHPLQLKLQVFKTLNRGWGIRALNDIPKGAFLCVYAGNLLTDATANLDGLNEGDEYLAELDYIEVVEQMKEGYEEDIPAADRKMDKRELAKQEESSEEESPSEDEGRAGTSDKEDDDFQPGYIGLGVMEFNKALRKRNKTKKHDEEKGKSKETEKEHTKDDTEDCITISDDEEVREPSRFTAQAGMGANAFISKYRSVRSHFGKDEACYIMDAKVQGNIGRYLNHSCTPNVFVQNVFVDTHDPRFPWVAFFALSHIRAGTELTWNYNYDVGSVPGKVLYCFCGAPNCRGRLL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-