Nmel006339.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Nomia melanderi
Gene Symbol
-
Assembly
GCA_003710045.1
Location
NW:1840684-1848112[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 20 0.52 31 4.4 5.8 2 23 243 265 242 265 0.96
2 20 0.022 1.3 8.7 2.6 1 23 315 337 315 337 0.97
3 20 0.12 7.3 6.3 1.6 1 23 386 408 386 408 0.98
4 20 0.023 1.4 8.6 0.1 1 20 463 482 463 484 0.94
5 20 0.0011 0.067 12.8 0.7 1 23 524 546 524 546 0.95
6 20 0.00048 0.029 13.9 0.1 1 23 593 615 593 615 0.97
7 20 0.00046 0.028 14.0 0.1 1 23 621 643 621 643 0.97
8 20 3.6e-06 0.00022 20.6 0.2 2 23 687 709 687 709 0.96
9 20 0.0079 0.48 10.1 0.6 3 23 718 739 718 739 0.93
10 20 8e-06 0.00049 19.5 0.3 2 23 748 770 747 770 0.96
11 20 3.3e-05 0.002 17.6 0.0 1 23 778 800 778 800 0.94
12 20 0.021 1.3 8.7 0.4 1 20 863 882 863 882 0.97
13 20 0.00013 0.008 15.7 0.1 1 23 900 922 900 922 0.98
14 20 4.5e-05 0.0027 17.1 0.9 1 23 940 962 940 962 0.97
15 20 0.0009 0.054 13.0 7.1 3 23 986 1007 984 1007 0.93
16 20 0.014 0.87 9.3 1.8 2 23 1068 1090 1067 1090 0.93
17 20 0.00015 0.0091 15.5 1.3 2 23 1121 1143 1120 1143 0.92
18 20 8.7e-05 0.0053 16.2 0.1 1 23 1150 1174 1150 1174 0.97
19 20 0.0036 0.22 11.1 1.1 1 23 1179 1202 1179 1202 0.97
20 20 0.031 1.9 8.2 2.3 2 23 1232 1254 1232 1254 0.94

Sequence Information

Coding Sequence
ATGGACGAAGTGGTGGTGTTGcagaatatagaaaatgtgTGTAGGCTGTGCCTCTCCGACGACGAGCCGAAATTGTCGGTGTTCGGGACGCAAGAAACTCCGGTATCGTTAGTCAGTAAGATACAAGCTTGCTTGTCGATTCAGATTTTAGCCACAGACAAGTTGTCAACTCAGATATGTgcacaatgtgttaaaaatgtGAATCAGTGGCATAATTATAAGGAAGCTTGTCTTCGATCGCAAGAAACATTACAGCAGTGGTTGGAAAAACATTTGCAATCTAGCCCAATGGTTGTAACAATCAAAGATGAACCTGTGGATCTCGACTTTTATGAAGACAATATTGAAGTTATTTCGGAATCCACTGTCGAGTCCGATGTGGAGTCAAACAATCTTGAAGAAAGTATAGAAGATTCTGTGAATACAGTTCATGTTCAAGAAATAACTGATGACGAAGGCGATCAGTTAAAAGCTCCGCCAATATTAACAAAAGATTTAGACATATGTATAAAGCCAGAGCCACAAGAAGACTATGACACGGATTGCACTATAGAGATAGAATCTGTTACTGGCAGTGAACTTGTTTTGAATCCACTTTCAAATAAAGAAGATACAGTAATGGAAGCTGATTCTACGCAGAAGTCAAACGCATCAGCATCACCaaccaaaaagaaaattagaagAGGCCCTCACACTCACTACAGAGGAACACGCGCGTTTAAGCAAAAATGTGTGCATTGTCAAATCTTTTtacattcgaaatattcttataCAAAACACATGGAGAGATTTCATACAGAAAAGCAAAATGGAGACACAAGTGCTGTACAGTTGAAAGACGAAGAAGAGTTAGTTGAAGATTTGGAGGATGAGTTAATGAGCATGGAGAAAGATGCTCCATTAACTCAAGTGCAACAGAACATTATCAGTCAATTGAAAACGTTCTCGTGTTATTCCTGTCAACAATCGTTCAACGATCGTAGAAGTACACTGTCTCATATTCGTCAGCATATGCCGGATCTGAGACCGTATACATGTATCGCGTGTTTGACAGAATTCCCGGATCGATCAATGTATAAACTGCATTGTGGCGCTTCGTTTGAGTGTGCAATGAAGATCGCATTGGTAATACCAAATGAaggcgaagaaaaatatttcacatgtaaCATGTGCCTACGTTCTATGCAAAATCGAAAGGAATTGCTCAGCCACCTTTCAAAACACTCTGACAAGCAGTATCAGCAACTGGTTTCGCCATCGAGATCACCGCCTAAATTGAAACCAATTTCTCCTCTACCAGCTTCTAAACAGGAACCTATAAAAAGATCGGTCTCAAGTGGACTGAATATTCCGCGTCCTTACAAAAACGGCGATCCAGCACACAATCACGTATGCGACTTATGCGGAATGATCTACAGATACAGACCCAATATGGTCAAGCACAGAGACTTGTGTCAACGTCTTCAACCGGAAGTCCGAACCTCCTACAAGTGTATACACTGTGGGATGACATACTTggtgtttaaaaaattccataaTCATATCACCTTAGATCACAAGAAGAAAGACTTCTTGTGTTCTGAATGTGGTGCCAAGTTTCGTGCTTCAAGTGACTATCTAGCGCATCATGAAACACACCGTGTCACGGCGAATAAAAAACCATCGCTTGAAAGAAAAGATTCTGGCAAGGGTGTGCAGAACTTCTCGACGCCCATTAAAGATTGGGATACGTTCGAGGCAGAGATGAACGCTAGCAGAATACCTGAAAGTGTCCAATATAGTTGCGCCTTATGCAACTTGGAGTTTGCCACGAGAGCTGAGTTGACCGAGCATAGAAACTTGCATCTGAAGGTAAAAATCTATTCCTGCGTAATTTGCCGTAGCATGTTCAGCAGTGCGGGCGCGTTAGAGATCCATATGAAGGACCATGGCATAGAGGATCCCAATGAGAGAAACGCGAATAGCTCGTGCGTAGAATATGGAACCGTGAACGAGAGCATGGAGAACACAAATCCGACGAACATGAGTGTTACATCAGACCCGGGTTCTAACAAGAATGAGTGTGCTCAATGTGGCAAAGTGTTCTCGAACTACGCGAACGTCAGGCGGCACATACGCAACATTCATAAGCCTAACAAGTCATACTTGGGTTGCCCTGAGTGTCCTCGCACCTTTAAGACCAAGGAGATTTTCGATAAGCATTTGACGAGTGAGCACAACAAACCCGCCAAATCAATGTTGCAGTGTCCCCAGTGCCCGAAGACGTTCGTCTTCCAAGCGAACCTAAATCTCCATTTTCAAACCGCTCATGGAGCAAAGAGAAGTGGTGGTTACGAATGCGACATTTGCGGTAAAACGTTCATTGAGGAAGCGTCTCTGAAAATACACCGCGGTTGGCATAACAGGACAAACTCGCGGTTGAGTCTACGTAACGCCATCGCCCCTACCGATAACGACAAGAAACCGATCGCTAACTCCATCACGATCGTACCTAAACAGGAGAAAGTTCTGAACGCCAGCTCAGACAAACCTGCCAGAGCAAGGAAATCGTTCCCCAATTCGCCATCAATGAAACCGGAAGGTAAATTCCAGTGTCAGGTATGTAACGACAAGTTCAACGACGTGACCGAGTTAAGAAAACACTTGTGGGACGTGCACTGTgcccataagaccgagaagtcCTTTACGGGCGAAGAGTTCCAGTGTGATGTTTGTTCCACTATTTTCGCCGAGAAGGAGGCGCTGAATATGCATATGCAGTGGCACAAGGCGTGTGCTGGCGTATCTCGAATCAGACGACCCAGAAATCAAGGAACCTTCCCGTGTGAAGTTTGCGGGAAGTTCTACAGCTCGAAGAAGGTCCTCTGGAGGCACAAGAAGCTCCACAAAGCCACGACTGTTGCGGCCGTAAAGTTCCAATCGCTAGGGAAGAAATCAATGCCTAACCAGCATCTGTGCAACATTTGCCACAAGATCTTCTGCAGCAACCAGTCATTGCAGCGTCACAGGATGAATTTGCACAGCGACTTGTTCAATCACCGGCAACAGGCGGTCTACTCAAGCACAAGGAGGATGTCCCAGGAGGAGCCCAGCTTGAAGAGGATGAAgcaagaggaagaagaggaggaggaggaggaggaggaggtccTATCGAAACCAGCCGTTCTAGCGAATTCGATGCATGCTGGCAAGAAGCCGGTTATGTGCCACGTGTGCAGGAAGTTCTTCGCGAACATGAGTGTGCTGTATAAACATAAGCAATTAATGCATAGTAAATCACGAATGATGAAAAACGTGGCAAAAGCTTCTACGACTTCGAGCACGCAATGCATACCGATATCGGGGAGTGATGGCAAGATGTCCTGTAACATTTGTTTTAAGTCGTTCTCTGGCCTGTCGAACCTGCGCCAGCATTTCACCATCAAGCACAAGAACAGTCCGCCAAAGTACGCATGCCCTATTGACGGATGTAAACTGATGTTCCCATCCCAGTCTACCCTGAAGGCTCACGAGATGACCCACACGACCATGATCTTCAACTGCAATCTGTGCGGCCGTCATGTATTCAACCGACAAGCAATGACCGACCACATGCTCACCGCTCATAACACCGTCTATGATGCGGGCAAGAGCAAGAACTTCCATCGGGAGACTGATTTGTCACTGTACGTTGTTCAAAACGCAGTGGACGCGACATGTCCCCATTGCAAGATTAAGTATCCGAACAACAGGGCCATGAAGATACATTACTTCAAGTTCCATGATACAGTGAACTaa
Protein Sequence
MDEVVVLQNIENVCRLCLSDDEPKLSVFGTQETPVSLVSKIQACLSIQILATDKLSTQICAQCVKNVNQWHNYKEACLRSQETLQQWLEKHLQSSPMVVTIKDEPVDLDFYEDNIEVISESTVESDVESNNLEESIEDSVNTVHVQEITDDEGDQLKAPPILTKDLDICIKPEPQEDYDTDCTIEIESVTGSELVLNPLSNKEDTVMEADSTQKSNASASPTKKKIRRGPHTHYRGTRAFKQKCVHCQIFLHSKYSYTKHMERFHTEKQNGDTSAVQLKDEEELVEDLEDELMSMEKDAPLTQVQQNIISQLKTFSCYSCQQSFNDRRSTLSHIRQHMPDLRPYTCIACLTEFPDRSMYKLHCGASFECAMKIALVIPNEGEEKYFTCNMCLRSMQNRKELLSHLSKHSDKQYQQLVSPSRSPPKLKPISPLPASKQEPIKRSVSSGLNIPRPYKNGDPAHNHVCDLCGMIYRYRPNMVKHRDLCQRLQPEVRTSYKCIHCGMTYLVFKKFHNHITLDHKKKDFLCSECGAKFRASSDYLAHHETHRVTANKKPSLERKDSGKGVQNFSTPIKDWDTFEAEMNASRIPESVQYSCALCNLEFATRAELTEHRNLHLKVKIYSCVICRSMFSSAGALEIHMKDHGIEDPNERNANSSCVEYGTVNESMENTNPTNMSVTSDPGSNKNECAQCGKVFSNYANVRRHIRNIHKPNKSYLGCPECPRTFKTKEIFDKHLTSEHNKPAKSMLQCPQCPKTFVFQANLNLHFQTAHGAKRSGGYECDICGKTFIEEASLKIHRGWHNRTNSRLSLRNAIAPTDNDKKPIANSITIVPKQEKVLNASSDKPARARKSFPNSPSMKPEGKFQCQVCNDKFNDVTELRKHLWDVHCAHKTEKSFTGEEFQCDVCSTIFAEKEALNMHMQWHKACAGVSRIRRPRNQGTFPCEVCGKFYSSKKVLWRHKKLHKATTVAAVKFQSLGKKSMPNQHLCNICHKIFCSNQSLQRHRMNLHSDLFNHRQQAVYSSTRRMSQEEPSLKRMKQEEEEEEEEEEEVLSKPAVLANSMHAGKKPVMCHVCRKFFANMSVLYKHKQLMHSKSRMMKNVAKASTTSSTQCIPISGSDGKMSCNICFKSFSGLSNLRQHFTIKHKNSPPKYACPIDGCKLMFPSQSTLKAHEMTHTTMIFNCNLCGRHVFNRQAMTDHMLTAHNTVYDAGKSKNFHRETDLSLYVVQNAVDATCPHCKIKYPNNRAMKIHYFKFHDTVN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00763380;
90% Identity
-
80% Identity
-