Nfab008545.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Nomada fabriciana
Gene Symbol
lolal
Assembly
GCA_907165295.1
Location
OU015697.1:12630079-12637113[-]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 2.5e-31 8e-29 100.2 0.1 1 103 23 121 23 128 0.94

Sequence Information

Coding Sequence
ATGACGGATAGCCAGCAGCAGTTTTGCTTGCGTTGGAACAACTTTCAAGCTAATATCACCAGCCAATTCGAGGCCCTCAGAGATGACGAGGACTTCGTCGATGTCACCTTCGCCTGCGATGGTAGACGACTCCAGGCGCACAAGGTTGTCCTTTCAGCGTGCAGCCCTTACTTCAAGGAGTTGTTCAAGACAAATCCATGCAAGCATCCGATAATATTTATGCGAGATGTGGAATTTGAACATCTGCAGTCTCTTTTGGAGTTCATGTACGCTGGAGAGGTTAACATATCCCAAGCAGAATTGCCTACTTTTCTACGAACTGCTGAGTCGTTACAAATCCGTGGCCTCACCGACTCCCAAAGTAATCAGCACAACAACGAAAAGCATTTGAAGACAAACAACATACACGCAACAAACGGCCGTGGGCTGATCTCACCAAATTTGGAGGAGGACTGTAGTAAAACTCCACCAACTTCAAGTCCTCCACCACTAAAAAGGCTGTGCAAACGAAGTGATTCGCCTCAGATATCTAGTCCAGTCCCAGCTGCGGCGGCCTGTACAACTGGAACGCCACGCACACGGCCATTAATTGAGCCACAGGTTCAACTTGACTGTTATAAAGATCTCGATATTGTTGAGCCAAAAATTGAATTACCAGAATATGGAAGTGATGACGATTGCTCTCCAAAGCAGGAGCTCAATACGCTGCCAAGTGGTTTTCTTAGCCTTGATGGCGGTATGGAAGTTTTACCGTCTTATCCTTCTTCTTATCAAGGGGGAGGAGCGGGCGGTGGCGGTGGAGGTGGTGGCAGCGGTGGATCATTAGAAGGTGGAATACCAGGGCCATCCCATGGCGGTAATGCGGAGCTGAACCAAGAACAACAAGCTGACCTACGCAAACTGCACTCGCTGGACCCACGCCCTTGTCCTGTCTGCAACCGCATGTACAGTAACTTGTCGAACCTGCGTCAGCACATGCGTCTGATCCACAACCCTCAGAGTGTCACATGCCCCCTCTGTAACAAGCCATTCAAGACCAAGCTCTACCTGAAGCGCCACCTGGTCAGCTTCCATGAGCTGAGCGTAGCAGACAGGCATCGTCAAGAAGAAATCTACCAACAACAACAGCCAAAAACGCAACAGGCTGGAGCGCAAACGCATCTACAAATTCAAGCGCAGCAGACAGATACAGTAAAATCCTTTGCGGGACCCAGGATCTCTATAGAGGAGGGCACAGCCACAACAAATTTGGAGAACAAGTCAAGAGCATTCCAAGATGGTGCTTACGAGGTCAATCAGACCAATGCTGATTCGAAGCACTTTCAGAGCAACATGATGCAGTTTGATGCTGCGTACCACTAA
Protein Sequence
MTDSQQQFCLRWNNFQANITSQFEALRDDEDFVDVTFACDGRRLQAHKVVLSACSPYFKELFKTNPCKHPIIFMRDVEFEHLQSLLEFMYAGEVNISQAELPTFLRTAESLQIRGLTDSQSNQHNNEKHLKTNNIHATNGRGLISPNLEEDCSKTPPTSSPPPLKRLCKRSDSPQISSPVPAAAACTTGTPRTRPLIEPQVQLDCYKDLDIVEPKIELPEYGSDDDCSPKQELNTLPSGFLSLDGGMEVLPSYPSSYQGGGAGGGGGGGGSGGSLEGGIPGPSHGGNAELNQEQQADLRKLHSLDPRPCPVCNRMYSNLSNLRQHMRLIHNPQSVTCPLCNKPFKTKLYLKRHLVSFHELSVADRHRQEEIYQQQQPKTQQAGAQTHLQIQAQQTDTVKSFAGPRISIEEGTATTNLENKSRAFQDGAYEVNQTNADSKHFQSNMMQFDAAYH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01065858; iTF_00084641; iTF_00087275; iTF_00085487; iTF_00088913; iTF_00088402; iTF_00085780; iTF_00089175; iTF_00087545; iTF_00088121; iTF_00086396; iTF_00084895; iTF_00086719; iTF_00676099; iTF_00225313; iTF_00220100; iTF_01421188; iTF_00218501; iTF_00218725; iTF_00223269; iTF_00231621; iTF_00874085; iTF_01067685; iTF_01420999; iTF_00222600; iTF_00873864; iTF_01067016; iTF_00223497; iTF_00220875; iTF_00228972; iTF_01419916; iTF_00228749; iTF_00229645; iTF_01420557; iTF_00226671; iTF_00226895; iTF_01069743; iTF_01418639; iTF_00684848; iTF_01069968; iTF_00220657; iTF_00223953; iTF_00229425; iTF_01068370; iTF_01068594; iTF_00224627; iTF_01418419; iTF_00224181; iTF_00140662; iTF_00219190; iTF_00140887; iTF_00221559; iTF_00233303; iTF_00215320; iTF_00219416; iTF_00233528; iTF_01067224; iTF_00214649; iTF_00215097; iTF_00221337; iTF_00222810; iTF_01420378; iTF_00217147; iTF_00676315; iTF_00224860; iTF_01419709; iTF_01066334; iTF_00214463; iTF_00225535; iTF_00231391; iTF_00217376; iTF_00219872; iTF_00685056; iTF_01067904; iTF_00762628; iTF_00763305; iTF_00763502; iTF_00024692; iTF_00024891; iTF_00762843; iTF_00866306; iTF_00866089; iTF_00865614; iTF_00866991; iTF_00866775; iTF_00865406; iTF_01539915; iTF_01539682; iTF_00864718; iTF_00864933; iTF_00861970; iTF_00864051; iTF_00864249; iTF_00862175; iTF_00863346; iTF_00863555; iTF_00860724; iTF_00860474; iTF_00861498; iTF_00861248; iTF_00862653; iTF_00862876; iTF_00360288; iTF_00360502; iTF_00963269; iTF_00963464; iTF_00964104; iTF_00963917; iTF_00964600; iTF_00962585; iTF_00964730; iTF_00962784; iTF_01169477; iTF_01169250; iTF_00215782; iTF_00216006; iTF_00228044; iTF_00228273; iTF_00227570; iTF_00227348; iTF_01419273; iTF_01417778; iTF_01418005; iTF_01419066; iTF_00118314; iTF_00118085; iTF_00226218; iTF_00225991; iTF_01070666; iTF_01066562; iTF_01070437; iTF_01122703; iTF_00303412; iTF_00303177; iTF_00983668; iTF_00983857; iTF_00216696; iTF_00216469; iTF_00962104; iTF_00961904; iTF_00183577; iTF_00183578; iTF_00183355; iTF_00183356; iTF_00982361; iTF_00982583; iTF_01069050; iTF_01069265; iTF_00306587; iTF_00306359; iTF_01424667; iTF_01424452; iTF_00983036; iTF_00983259; iTF_00184221; iTF_00184014; iTF_00217821; iTF_00218024; iTF_00230333; iTF_00230104; iTF_00734206; iTF_00734063;
90% Identity
iTF_01421188;
80% Identity
iTF_01065858;