Npro012992.1
Basic Information
- Insect
- Noctua pronuba
- Gene Symbol
- Zfa
- Assembly
- GCA_905220335.1
- Location
- LR999917.1:10803075-10820993[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 0.0048 0.44 11.8 1.4 1 23 259 281 259 281 0.98 2 10 0.077 7.1 8.0 2.3 1 23 288 310 288 310 0.98 3 10 0.00016 0.015 16.4 5.2 2 23 343 365 342 365 0.94 4 10 0.00056 0.051 14.7 0.8 2 23 372 394 371 394 0.96 5 10 1.1e-05 0.0011 20.0 0.2 1 23 407 429 407 429 0.97 6 10 2e-05 0.0018 19.3 0.3 1 22 435 456 435 460 0.94 7 10 0.00024 0.022 15.9 1.1 2 23 469 491 468 491 0.95 8 10 3.8e-05 0.0035 18.4 1.3 1 23 497 520 497 520 0.97 9 10 1.8e-05 0.0016 19.5 0.2 1 23 529 551 529 551 0.98 10 10 0.0023 0.21 12.8 0.4 1 19 557 575 557 580 0.90
Sequence Information
- Coding Sequence
- ATGGGTGAAAGTGTTACTTGGACCCACAGTAATGTGGAGGAAAAACCCGAATCAACAACGAAGTATTGTTTTGGATGTTTGTGTATAAATGAGGAGAAAAATGTACAAAACTATGCCTTCCAAAGCGGTCCCCTCAAGAATATATTTCAGATGGACTGCATATCCCTGTGTTATCTGTGCAAGAGGATGGCTCAACACACTGAGCTGTTCATACAGAATGTGCAAAGTAATCAAATACTATTGGAAAACTTTCAGAATGTAATGGACGATACCTTAAAATCAGTGCGCACGCAGATCCAACCGCTAGTCAATTTAACGAAAGTGCCATTTGATGTGATACAACTAGCAGAGAGAGACAGCAACAGTTCCGAGGAAACCTTCTCTGTCATATGCTATCGGAGTAAGAGTAGAGATTTGCAGGTCAAGACTGAGATGAAGGAAGAGGAGTATATGGAAAACCTGGAAGGAGAGTTTATTAATGGTGGTGATGAATTTCCCGAGTCATACGTAAAAGATGAAGAAGATTCATTTCCTCTCAAAGCCTTACTGAAAGAAGAATTTCAACTAGAAGACATCGATAGCCTGGACTTGATGACTCTTAGTGCTACACTCAAAAAGAACAAACATAATAAGAGGAAAAGTAAAATAAAACGAGAAAATTTGAATGAGATGAAGAGAGACGTTCCTAAAGTAAAAACAATATACATCACTAGAGAACAATGCATGGAAGAACGAGCGAAAATGGAGCAGGACCAGAAATATTTGGAGCTGGCTTACAAATGTGGGAACTGCATCAAAGGATTCAGCTTTAAAGGCAGCTATGATAAGCATATGGAGAAACATAATCAGTGCATGGGAAAGTACGAATGTGATATTTGTAAACAGAGAATGCAGACTGAACACAGACTGGTCAGCCATATGAGGTATCATCTGATCCGCTACAAATGTGCAGAATGTGGCCTAATTAGAAACTGTAGGATGACGATACAAGACCACTACAACGCATATCACAGTCAGGGCTATCAAATGTGTTCCTTTTGCAGCAAGACTTTCAAACGCCAGACGTCTCTCCGCAAGCACATACACTACACACACAGGCACAAGGGCCGCGTACAGTGCGCGTACTGCCACAAGACGTACGCCGACAAAGGCATACTACGCAATCACATGATCATGAAACATTCCAAAGAAGTATCAGCGGCTCCCATCAGCAAGAAGTATGTCTGCCAGGAGTGCGGCATGGCGTTCAAGGCACCTTCGCAATTGAGGAAGCACGGCAGCAAGCACTCGGACAGCCGGGATTACTACTGTGTGGAGTGTGATAAGACTTTCAAATCGGATGCCACATTAAAAAACCACTTGAAGACTGCAGCTATCCACGTCAGTTATTTAGAATTACCATTACCCTGCCTGCATTGTGACAAACGTTTCGCGATACGAAGGGATCTAGAGAGACACACGAACAGAGTACACCTCAATATCAAACCTTTTACTTGTGATAGATGTGATAAGACTTACGTGAACAGCTGGTCTTTGAAAGAACACAAGCGGTTGACCCACGAAGGATATAAGAGACCGCTGCAGTTTCCATGCCCTATGTGCGATAAGGTTTTTGATCGCAATCAGATCCTTAAAGGCCACATCCGCACGCACACTGGCGAGCGTCCGTACCAGTGCAGCAAGTGTCCAGCTTCATTCAGTCAGTCCAGCATACTTCGTACCCATGATAGACTCATACACCTTAAACTGACCAGGGATGGACGGCCTAAGGTCAAATAG
- Protein Sequence
- MGESVTWTHSNVEEKPESTTKYCFGCLCINEEKNVQNYAFQSGPLKNIFQMDCISLCYLCKRMAQHTELFIQNVQSNQILLENFQNVMDDTLKSVRTQIQPLVNLTKVPFDVIQLAERDSNSSEETFSVICYRSKSRDLQVKTEMKEEEYMENLEGEFINGGDEFPESYVKDEEDSFPLKALLKEEFQLEDIDSLDLMTLSATLKKNKHNKRKSKIKRENLNEMKRDVPKVKTIYITREQCMEERAKMEQDQKYLELAYKCGNCIKGFSFKGSYDKHMEKHNQCMGKYECDICKQRMQTEHRLVSHMRYHLIRYKCAECGLIRNCRMTIQDHYNAYHSQGYQMCSFCSKTFKRQTSLRKHIHYTHRHKGRVQCAYCHKTYADKGILRNHMIMKHSKEVSAAPISKKYVCQECGMAFKAPSQLRKHGSKHSDSRDYYCVECDKTFKSDATLKNHLKTAAIHVSYLELPLPCLHCDKRFAIRRDLERHTNRVHLNIKPFTCDRCDKTYVNSWSLKEHKRLTHEGYKRPLQFPCPMCDKVFDRNQILKGHIRTHTGERPYQCSKCPASFSQSSILRTHDRLIHLKLTRDGRPKVK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01093377;
- 90% Identity
- iTF_00928979;
- 80% Identity
- -