Nfla005488.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Nineta flava
Gene Symbol
drl
Assembly
GCA_963920215.1
Location
OY986040.1:141625554-141631205[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 0.0032 0.12 13.4 2.8 1 21 134 156 134 157 0.96
2 10 6.1e-08 2.3e-06 28.3 0.1 1 23 168 191 168 191 0.98
3 10 0.00071 0.026 15.5 0.6 2 23 205 226 204 226 0.97
4 10 1.4e-06 5.3e-05 24.0 0.3 1 23 232 254 232 254 0.99
5 10 6.4e-06 0.00024 21.9 1.8 1 23 260 282 260 282 0.99
6 10 0.00061 0.023 15.7 3.7 1 23 288 310 288 310 0.95
7 10 0.0002 0.0074 17.2 0.9 2 23 317 339 316 339 0.94
8 10 0.0023 0.086 13.9 0.5 2 23 346 367 345 367 0.96
9 10 1.6e-05 0.00061 20.6 2.7 1 23 373 395 373 395 0.98
10 10 9.6e-05 0.0036 18.2 0.6 3 23 403 424 402 424 0.95

Sequence Information

Coding Sequence
ATGGAAGAAATGATCACTGATGAAGTAATTGATTTGATACCGACTGAAGTCAAATCAGAATCCAATGAAGATCAAATTGATGCAGTCGATGCGATCGGTTTAGAAGAAGTACAAGTTGATGATGCAGAAACCCAAAACGAGCCATCTTCAGAGATTACAGACGTTAAAATGATTGAATGTCCTGTTTGTAGATTGAATGTCATATCATTTATGATGGAAGAACATAAAAATACGTGTTCCGGTGCGGATGAAAGTATACTAGGAACTGATAATTATTCAGTCGATGATTTAGATGAAGAAGAGGAAGAAGAAGATCGTAAAGATATCAGTTTAGAGCCTGATTCTGCTGATGGTGGTGGTAATGAAGATGATGAAGCCGATGGCGatgataaaaaagtttataaatgtcCAAATCAAGGTTGtacaaaagtttacaaaaagaaaTTCTACTTAAGTCGACATTTAAAACATACCAATTGTACCGGtttattgcaagttaaatatgaATGCAAGGTTTGTGGTAAAGCTTATTCACGACCAGATAATTTGAGGGCTCATTTAAAATCAGCTCATGTTGATAATAACCAAGCTCCGCCTAAAGATAAATCGATCACTTGTCAACATTGtgataaagttttaaaaaataaagctATTTTATTGGTGCATATGCGAATTCATACtgGCGAAAGGCCGTATAAATGTGATATCTGTCCAAAGGCATTTCCAACAAGTGGTGCTTATCAAAAACATAAGCGAGTACATACTGGAGAACGACCATTCCAATGTCCACAGtgTAAACGTCGATTCACAGCCAAAGAAGTGTTAAATCGACACATGAAAACACATTCATCAATCAAACCGCACGTTTGTATGTTCTGCAACAAGAGTTTTGTACAAGCAATGCAGTTACGTGCACACATGTTCCATCATACGGGCGAATACTCATGTGTTTGTAAAACATGTGGAGCTGCCTTTAGCAAACAGAGTGCTCTTACGCTACACGTTAAGTATGAACATCAAGGAGCGAAGCCGTTGGAGTGTGAGGTATGCAAGAAAACATTCTTAACGAAAAACTTTTTGGCACGACATCAGATTATTCATTCTGGTGTCAAAGATCACGAATGTACCAACTGCAAAAAACGTTTCATATCGAAGCCAGCATTAAAGACACACATGCTAACACATCGTCATGAAGAACCAAGAATCTGTTACGATTGCGGCCGAGCCTACATTCGTTTGGATTGTTTAATTCGTCATATGCGTGCTAAACATCGTGACGTTCTACAAGATATGATTGCATCGGCTGAAACGAAAAAAATCCGACAACTTGTTTTATCCGCTCAGCCCCAATTGGAGAAAGGCACCAGTTGGTCGGATGATATATTCGtagaaaatctaaaaaaattattaatcattttaattgatgagataacattaaaaaatttcggTTGGCCACAACGACcgattgataaaattttagattCGTTAATTGTACGGTGCGGTAGTACACCGGTTACCGATGACAGTATCGAATTTATCGATCGTTTACGGGAGAATACGAAAATACTATTTACGGGAATTATCAACGATGATGCGTTGGAAGTACTCTTGAATAATAATACGGTGGATGAAGTTGTTAATTTTGTGTTACAGTTATCGGCGGTACCATCGGAAACAAATGAATCGGATGACGTTAAACTGTTCATTAAAGCTTAA
Protein Sequence
MEEMITDEVIDLIPTEVKSESNEDQIDAVDAIGLEEVQVDDAETQNEPSSEITDVKMIECPVCRLNVISFMMEEHKNTCSGADESILGTDNYSVDDLDEEEEEEDRKDISLEPDSADGGGNEDDEADGDDKKVYKCPNQGCTKVYKKKFYLSRHLKHTNCTGLLQVKYECKVCGKAYSRPDNLRAHLKSAHVDNNQAPPKDKSITCQHCDKVLKNKAILLVHMRIHTGERPYKCDICPKAFPTSGAYQKHKRVHTGERPFQCPQCKRRFTAKEVLNRHMKTHSSIKPHVCMFCNKSFVQAMQLRAHMFHHTGEYSCVCKTCGAAFSKQSALTLHVKYEHQGAKPLECEVCKKTFLTKNFLARHQIIHSGVKDHECTNCKKRFISKPALKTHMLTHRHEEPRICYDCGRAYIRLDCLIRHMRAKHRDVLQDMIASAETKKIRQLVLSAQPQLEKGTSWSDDIFVENLKKLLIILIDEITLKNFGWPQRPIDKILDSLIVRCGSTPVTDDSIEFIDRLRENTKILFTGIINDDALEVLLNNNTVDEVVNFVLQLSAVPSETNESDDVKLFIKA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00333105;
90% Identity
-
80% Identity
-