Basic Information

Insect: Nicrophorus vespilloides
Gene Symbol: L
Assembly: GCA_001412225.1
Location: NW:72990-96544[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 20 4.7e-07 3.2e-05 23.5 0.6 1 23 117 139 117 139 0.99

2 20 0.092 6.3 6.9 6.0 1 23 145 167 145 167 0.97

3 20 3.3e-06 0.00022 20.9 3.9 1 23 173 195 173 195 0.99

4 20 0.0006 0.041 13.8 1.2 1 23 201 223 201 223 0.97

5 20 0.0011 0.076 12.9 0.9 1 23 249 272 249 272 0.97

6 20 0.69 47 4.1 1.8 3 23 305 326 303 326 0.93

7 20 0.005 0.34 10.9 0.1 1 23 361 384 361 384 0.95

8 20 0.26 17 5.5 0.3 3 23 512 532 511 532 0.96

9 20 0.2 14 5.8 4.8 3 23 542 563 541 563 0.92

10 20 0.044 3 7.9 0.6 1 23 568 591 568 591 0.92

11 20 0.00031 0.021 14.7 0.6 1 23 653 676 653 676 0.97

12 20 7.4 5e+02 0.9 2.0 1 21 721 742 721 745 0.63

13 20 0.00052 0.035 14.0 4.4 2 23 756 777 755 777 0.97

14 20 3.6e-05 0.0024 17.6 0.7 1 23 786 808 786 808 0.97

15 20 4.9 3.3e+02 1.5 0.4 2 16 886 899 885 901 0.75

16 20 0.017 1.2 9.2 0.3 1 23 935 957 935 957 0.94

17 20 0.097 6.6 6.8 0.2 2 23 966 987 965 987 0.95

18 20 0.0012 0.079 12.9 0.1 1 23 995 1017 995 1017 0.97

19 20 0.0023 0.15 11.9 1.6 1 23 1024 1046 1024 1046 0.97

20 20 0.00071 0.048 13.5 0.5 1 21 1060 1080 1060 1081 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	20	4.7e-07	3.2e-05	23.5	0.6	1	23	117	139	117	139	0.99
2	20	0.092	6.3	6.9	6.0	1	23	145	167	145	167	0.97
3	20	3.3e-06	0.00022	20.9	3.9	1	23	173	195	173	195	0.99
4	20	0.0006	0.041	13.8	1.2	1	23	201	223	201	223	0.97
5	20	0.0011	0.076	12.9	0.9	1	23	249	272	249	272	0.97
6	20	0.69	47	4.1	1.8	3	23	305	326	303	326	0.93
7	20	0.005	0.34	10.9	0.1	1	23	361	384	361	384	0.95
8	20	0.26	17	5.5	0.3	3	23	512	532	511	532	0.96
9	20	0.2	14	5.8	4.8	3	23	542	563	541	563	0.92
10	20	0.044	3	7.9	0.6	1	23	568	591	568	591	0.92
11	20	0.00031	0.021	14.7	0.6	1	23	653	676	653	676	0.97
12	20	7.4	5e+02	0.9	2.0	1	21	721	742	721	745	0.63
13	20	0.00052	0.035	14.0	4.4	2	23	756	777	755	777	0.97
14	20	3.6e-05	0.0024	17.6	0.7	1	23	786	808	786	808	0.97
15	20	4.9	3.3e+02	1.5	0.4	2	16	886	899	885	901	0.75
16	20	0.017	1.2	9.2	0.3	1	23	935	957	935	957	0.94
17	20	0.097	6.6	6.8	0.2	2	23	966	987	965	987	0.95
18	20	0.0012	0.079	12.9	0.1	1	23	995	1017	995	1017	0.97
19	20	0.0023	0.15	11.9	1.6	1	23	1024	1046	1024	1046	0.97
20	20	0.00071	0.048	13.5	0.5	1	21	1060	1080	1060	1081	0.94

Sequence Information

Coding Sequence: ATGTCACGAAGGAAACAAGCAAATCCTGCTAAACTGGGGGAGACTGAGAGTACGGATGCtttggaggaggaggaggacacGCCGAGTTCTTCTAAAGAGATGATGATGGGAATGTTCAAGAATGGAGGTGATAACAATGTGTTTGATGACGTCGATATTAAGGAGGAGGACGAGATACTGGACGACGATGATGAGGACGAGGATGATGGGAGTTTATTAAACGGACAGGGAAGTTCGCCGTCGAGCAGCTCGGAGCAAGCGTCCCCTGCAAGTTCCTGCCAGAGTTCGCTCAGCGACACGCCGGAGGCCGAAGAGCCGTACACGATGGGCGCGACGGCTACAACCCCTTACGAATGCAATATTTGCAAAAGGGCATTCGCCAGGTCATCACTATTAAGCAAACACGTACAGACGCACACCGAGCAGTTGCAATTCAGCTGTCCTTATTGCCGTCGCCTGTTCAAGCACAAGAGGTCCAGAGATAGACACACCAAGCTGCACACCGGAGACAAGAAGTATAAGTGTCTCCACTGCGATTCGGCGTTTGCAAGAAGCGACCACTTAAAAATTCACATGAAGACCCACGACAACAAAAAGCCTCATCAATGTGAATTATGCAATCGCGGCTATAACACCGCTGCGGCTTTGGCTTCCCATCAACAGCATCATTCGAAGCAGGAGCAAAGGAGATGCGGCAGTAGCGCCAGTAGGAGCAGCGCCGTCAGCACACCGAGTCCTGGTAACTTCCGATGTCTACAATGTCCGGACACTTTCGAAAAACCGGAGCATCTTCAGAACCACTTGCAAGTGAGCCATAAAAATATCTCGCCTCCGGCATCTCatccaaataatttattaatggacGCCAgtttcaatatattgaaaacgGCCATCGATCTGCCGAAAATCGCCTGCATGTATTGCGGAAAAGATTTCCTCAGCATGAACCACATGTATCAGCACATCCATTCCGAGCACCGTGCTATTTTCAATAGCATCTCGCAAAGCTTCACTCCGCTACCTTCGCCGGTTATGGAGAATCTATCTCCGAAGACGTCCAGGCAGAACAGCTCGCCGACCTACGCGTGTGATCGCTGCACGATGCGATTCGATTCGCCAATTTTACTTCAGGAGCATATCGAGAACGTCCACTGGGGACCAACTGGACTATACAAGTATGACTTCACGACGATGTCGAACTCCTCGGGCATCTCCAACGAGAAGTCATCGCACTCGTTAGCAGCCACCTCGCAATCCAAGCCTACCGATCTGAGCAGAAAACGGCGTTCTGAGAACCCTCTTGACTTCAAGTTGGATAAGAGGAAAGCCGATGAAGCGGCACTAGTCAGCAAGCAGACCTCGTCTCCATCCACTGGTAGTCCTTACGAATCTAATGACAAACCTTGCATATGTTCGTATTGTTATGCGCAAATGCCAAACTTCAAAATGTTCCTCCTTCATATGGAAACCCATGTGTCTATGAGCACACCATCCACCCCTCTACCTCTTTCTACGAACAACGTGATTGGGTGTTGTCCCCTTTGCGGTGAACCGGCTCGCAGCACCCTAGAACTGGGCCGCCATATCTTCAGTCACGCCATCAGCAACGTCACAGCTCGATGCTGTCACTGTTGCAAGAAACCCTTCGACCAAATCGATGACCTACAAAAACACCTCCTCGAAGCCCACTCCCAAACCGTCTACAAGTGCAGCATCTGCAACGATATATTCGAAACTCAGCTAGCTTTACAGATGCACTTTTCGAACAAACATAGTCCCGAGTGTAAGCATTACAGGTGCAACCTCTGCTGCGACCAAGTTTTCCACGACCGTCTCACAGCCGAGCTTCACGTAAATATGAAGCACAGTATTCAGGCGCCTCTGAGCTCAAGTGTGCGAAATTATCACCACATGTCCAGATTTCCTGAAATCGAAACTCGCGCTGAATTTTCCATTTACCAATGCCCCTTCTGTCAGAAAGCCTTTAAAGACGAGTACCTGCAATATGTACACATCCTCAAGGAACACAACGAGGTGCGCGAGGGTGAAAATTATCTACTAGACTCCAGTAACCGTCGCATCCCGTCCGCTTCGCCCAATGTCGCATATAGCAAGACAAGCTCATCTCCCGACAAAATTGACCTTGGTAAGATTGGTAACTACAGTTGCGAGATTTGCAATAGGTCTGACATAGCCAGTGAAGCTGAGCTAACTGCTCACAAGAAATTGCACCATGCTAAAACCAAAGTAGGTACTTTAAGTTTACAATGCGCATACTGCAACGAGCACTGCAAATCCCGCAACGACCTGGAGAACCATATGAAGTCGCACCAAGTGTCATGCGGCAAAGGTAAGCACAAGTGCAATATCTGCGATGAAATATTTACGTCCAACGGCACATTGGCCGAACATAAGCTATCTCATTGCAAGATAGTCGCTGGTAGCAGTTGCACCCAATGCAAAGCAGTATTACTAGACGAGCAATCATTTTATAACCATCAACTCCAACACAGCAACACGTCCGCAATCAACAAGCAAAACTCGCAAATTTCGCTACCCGCAAACTGCATCATATGTTGTCAGACCTTACAGACCGACGTCGAGATTAAACTTCACGCGAAATTCCATCTGCGgcatttgttacaaaaagaattaatatgtgccatttgcaacaagaTGTGTGACAACCACTTATTAAAACAcgtagaaaaaaacaacatcaatGTTCCCATATGCATTGAATGCATGAAAGCTACCAACGGATCCTCTCCATCGTCCTTGATCGCATCACAGAGCAAACTATTCGCATGTCTCAAGTGTTCTCAGACATTCGACACGGAGGATGAGATTAAAGCGCACACCACTGAACACATGATGAACGAAGAGCCCAGCCTCGAGTGTCACCTATGCCGCAACGTTCTGCCCTCTCCGACCAAACTTCAGGTTCACCTGATAGAGCACAATTTTATGGGAATGGGCCAATATCGCTGCTACGTCTGCTCTTCCGTCTTTACTACAGCCATGGGCCTTCGCACCCACATCATTGCACACGGCCTCATCCATCGACCCTACGAATGTACCGACTGCAAAATGAAGTTCTTCTTTGAGACGGAACTTGAAAACCATCGCTACGTCCATCTGCATCctaatatgtatacaaaaaatggtAGCGAATACTTTGAGTGCAAGTCCTGCGGTCGGTCCTTCAACGACAACATCTATTACAAGGAGCACGTGCAGAGTTGTCCGATGTCCACAAAGGACATTGAACAATCGCATGAGaccaaaaaaattgaaattaagaagGAAGAGTTGAATACCGAATGTGAGCACGAATTAGCTacaatcaacaataataagtaa
Protein Sequence: MSRRKQANPAKLGETESTDALEEEEDTPSSSKEMMMGMFKNGGDNNVFDDVDIKEEDEILDDDDEDEDDGSLLNGQGSSPSSSSEQASPASSCQSSLSDTPEAEEPYTMGATATTPYECNICKRAFARSSLLSKHVQTHTEQLQFSCPYCRRLFKHKRSRDRHTKLHTGDKKYKCLHCDSAFARSDHLKIHMKTHDNKKPHQCELCNRGYNTAAALASHQQHHSKQEQRRCGSSASRSSAVSTPSPGNFRCLQCPDTFEKPEHLQNHLQVSHKNISPPASHPNNLLMDASFNILKTAIDLPKIACMYCGKDFLSMNHMYQHIHSEHRAIFNSISQSFTPLPSPVMENLSPKTSRQNSSPTYACDRCTMRFDSPILLQEHIENVHWGPTGLYKYDFTTMSNSSGISNEKSSHSLAATSQSKPTDLSRKRRSENPLDFKLDKRKADEAALVSKQTSSPSTGSPYESNDKPCICSYCYAQMPNFKMFLLHMETHVSMSTPSTPLPLSTNNVIGCCPLCGEPARSTLELGRHIFSHAISNVTARCCHCCKKPFDQIDDLQKHLLEAHSQTVYKCSICNDIFETQLALQMHFSNKHSPECKHYRCNLCCDQVFHDRLTAELHVNMKHSIQAPLSSSVRNYHHMSRFPEIETRAEFSIYQCPFCQKAFKDEYLQYVHILKEHNEVREGENYLLDSSNRRIPSASPNVAYSKTSSSPDKIDLGKIGNYSCEICNRSDIASEAELTAHKKLHHAKTKVGTLSLQCAYCNEHCKSRNDLENHMKSHQVSCGKGKHKCNICDEIFTSNGTLAEHKLSHCKIVAGSSCTQCKAVLLDEQSFYNHQLQHSNTSAINKQNSQISLPANCIICCQTLQTDVEIKLHAKFHLRHLLQKELICAICNKMCDNHLLKHVEKNNINVPICIECMKATNGSSPSSLIASQSKLFACLKCSQTFDTEDEIKAHTTEHMMNEEPSLECHLCRNVLPSPTKLQVHLIEHNFMGMGQYRCYVCSSVFTTAMGLRTHIIAHGLIHRPYECTDCKMKFFFETELENHRYVHLHPNMYTKNGSEYFECKSCGRSFNDNIYYKEHVQSCPMSTKDIEQSHETKKIEIKKEELNTECEHELATINNNK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01058615;
90% Identity: iTF_01058615;
80% Identity: -