Basic Information

Insect: Nicrophorus investigator
Gene Symbol: L
Assembly: GCA_963457615.1
Location: OY735146.1:11227099-11233749[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 20 6.3e-07 5.7e-05 23.6 0.6 1 23 76 98 76 98 0.99

2 20 0.12 11 6.9 6.0 1 23 104 126 104 126 0.97

3 20 4.4e-06 0.0004 20.9 3.9 1 23 132 154 132 154 0.99

4 20 0.0008 0.072 13.8 1.2 1 23 160 182 160 182 0.97

5 20 0.0015 0.14 13.0 0.9 1 23 208 231 208 231 0.97

6 20 0.91 83 4.2 1.8 3 23 264 285 262 285 0.93

7 20 0.0067 0.61 10.9 0.1 1 23 320 343 320 343 0.95

8 20 0.34 31 5.5 0.3 3 23 472 492 471 492 0.96

9 20 0.27 25 5.9 4.8 3 23 502 523 501 523 0.92

10 20 0.059 5.3 7.9 0.6 1 23 528 551 528 551 0.92

11 20 0.00041 0.037 14.7 0.6 1 23 613 636 613 636 0.97

12 20 9.9 9e+02 0.9 2.0 1 21 681 702 681 705 0.63

13 20 0.00069 0.063 14.0 4.4 2 23 716 737 715 737 0.97

14 20 2.2e-05 0.002 18.7 0.8 1 23 746 768 746 768 0.98

15 20 0.34 31 5.5 0.2 1 16 845 859 845 862 0.79

16 20 0.023 2.1 9.2 0.3 1 23 895 917 895 917 0.94

17 20 0.13 12 6.9 0.2 2 23 926 947 925 947 0.95

18 20 0.0015 0.14 12.9 0.1 1 23 955 977 955 977 0.97

19 20 0.003 0.28 12.0 1.6 1 23 984 1006 984 1006 0.97

20 20 0.0009 0.082 13.7 0.5 1 21 1020 1040 1020 1041 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	20	6.3e-07	5.7e-05	23.6	0.6	1	23	76	98	76	98	0.99
2	20	0.12	11	6.9	6.0	1	23	104	126	104	126	0.97
3	20	4.4e-06	0.0004	20.9	3.9	1	23	132	154	132	154	0.99
4	20	0.0008	0.072	13.8	1.2	1	23	160	182	160	182	0.97
5	20	0.0015	0.14	13.0	0.9	1	23	208	231	208	231	0.97
6	20	0.91	83	4.2	1.8	3	23	264	285	262	285	0.93
7	20	0.0067	0.61	10.9	0.1	1	23	320	343	320	343	0.95
8	20	0.34	31	5.5	0.3	3	23	472	492	471	492	0.96
9	20	0.27	25	5.9	4.8	3	23	502	523	501	523	0.92
10	20	0.059	5.3	7.9	0.6	1	23	528	551	528	551	0.92
11	20	0.00041	0.037	14.7	0.6	1	23	613	636	613	636	0.97
12	20	9.9	9e+02	0.9	2.0	1	21	681	702	681	705	0.63
13	20	0.00069	0.063	14.0	4.4	2	23	716	737	715	737	0.97
14	20	2.2e-05	0.002	18.7	0.8	1	23	746	768	746	768	0.98
15	20	0.34	31	5.5	0.2	1	16	845	859	845	862	0.79
16	20	0.023	2.1	9.2	0.3	1	23	895	917	895	917	0.94
17	20	0.13	12	6.9	0.2	2	23	926	947	925	947	0.95
18	20	0.0015	0.14	12.9	0.1	1	23	955	977	955	977	0.97
19	20	0.003	0.28	12.0	1.6	1	23	984	1006	984	1006	0.97
20	20	0.0009	0.082	13.7	0.5	1	21	1020	1040	1020	1041	0.94

Sequence Information

Coding Sequence: ATGCTGTTCAAAGGGAAGAGCAGCCGGCTGGAAATGGTCATCGAGAAAATACAATCGAATAAGGAAACCACCGAGGATACACCTGACGACTCGAAACCCGGACAGGGAAGTTCGCCGTCGAGCAGCTCGGAGCAAGCGTCCCCTGCAAGTTCCTGCCAGAGTTCGCTCAGCGACACGCCGGAGGCCGAAGAGCCATACACGATGGGCGCGACGGCTACAACCCCTTACGAATGCAATATTTGCAAAAGGGCATTCGCCAGGTCATCACTATTAAGCAAACACGTACAGACGCACACGGAGCAGTTGCAATTCAGCTGTCCTTACTGCCGTCGGCTGTTCAAGCACAAGAGGTCCAGAGACAGGCACACCAAGCTGCATACCGGAGACAAGAAGTATAAGTGTCTCCACTGCGACTCGGCGTTTGCAAGAAGCGACCACTTAAAAATTCACATGAAGACACACGACAACAAAAAGCCTCATCAATGTGAATTATGCAATCGCGGCTATAACACCGCTGCGGCTTTGGCTTCCCATCAGCAGCATCATTCCAAACAGGAGCAAAGGAGATGCGGCAGTAGTGCCAGTAGGAGCAGTGCCGTCAGCACACCCAGTCCTGGTAACTTCCGATGTCTCCAATGTCCGGACACCTTTGAAAAACCGGAACATCTTCAGAACCACTTACAAGTGAGCCATAAAAATATCTCACCCCCGGCATCTcatccaaataatttattaatggacGCCAGCttcaatatattgaaaacGGCCATCGATCTGCCGAAAATCGCCTGCATGTATTGCGGAAAAGATTTCCTCAGCATGAACCACATGTACCAGCACATCCATTCCGAGCACCGTGCTATTTTCAATAGTATCTCGCAAAGCTTCACTCCGCTACCTTCGCCGGTTATGGAGAACCTATCTCCGAAGACGTCCAGGCAGAACAGCTCGCCGACCTACGCGTGCGATCGCTGCACGATGCGATTCGATTCGCCGATTTTACTCCAGGAGCACATCGAGAATGTCCACTGGGGACCAACTGGACTATACAAGTATGACTTCACGACGATGTCGAACTCCTCTGGCATCTCCAACGAGAAGTCATCGCACTCGTTAGCTGCCACCTCGCAATCCAAGCCTACCGATCTGAGCAGAAAACGGCGTTCCGAGAACCCTCCCGACTTCAAGCTGGATAAGAGGAAATCATCCGATGAAACGACCCTAGTCAGCAAGCAGACCTCGTCTCCATCCACTGGTAGTCCTTACGAATCTAACGACAAACCTTGCATATGTTCGTACTGTTACGCGCAAATGCCAAACTTCAAAATGTTCCTTCTGCATATGGAAACCCACGTGTCTATGAGCACGCCATCCACCCCTCTACCTCTCTCTACGAACAACGTGATTGGGTGTTGTCCCCTTTGTGGCGAACCGGCTCGCAGCACCCTAGAACTGGGCCGCCATATTTTTAGTCACGCCATCAGCAACGTCACAGCTCGATGCTGTCATTGCTGCAAGAAGCCCTTCGACCAGATCGATGACTTACAAAAACACCTCCTCGAAGCCCACTCCCAAACCGTCTACAAATGCAGCATCTGCAACGACATATTCGAAACTCAGCTAGCTTTACAGATGCACTTCTCGAACAAACATAGTCCTGAGTGCAAGCATTATAGGTGCAACCTCTGCTGCGACCAAGTTTTCCACGACCGCCTCACAGCCGAACTCCACGTGAACATGAAGCACAGCATTCAAGCACCTTTGAGCTCAAGTGCGCGGAACTATCACCATATGTCCAGATTTCCTGAAATCGAAACTCGCGTTGAATTTTCCATTTACCAATGCCCCTTCTGTCAGAAAGCCTTCAAAGACGAGTACCTGCAATATGTACACATCCTCAAAGAACACAATGAGGTGCGCGAGggtgaaaattatttacttgacTCCAGTAACCGTCGCATCCCGTCCGCTTCGCCCAATGTCGCATACAGCAAGACAAGCTCATCTCCTGACAAAATTGACCTTGGTAAGATTGGTAACTACAGTTGCGAGATCTGCAATCGGTCTGACATTGCCAGCGAAGCTGAGCTAACTGCTCACAAGAAGTTGCACCACGCTAAAACCAAAGTAGGTACTTTAAGTTTGCAATGCGCATACTGCAATGAGCACTGCAAATCTCGCAACGACCTGGAGAATCACATGAAGTCGCACCAAGTAGCATGCGGCAAAGGTAAGCACAAGTGTAATATCTGCGATGAAATATTCACGTCCAACGGCACCTTGGCCGAACATAAGCTAACTCATTGCAAGATAGTCGCCGGTAGCAGTTGCACCCAATGCAAGGCAGTATTACTAGACGAGCAATCATTTTATAACCATCAGCTCCAACACAGCAACACGTCCGCAATCAACAAGCAAAACTCGCAAATTTCGCTACCCGCAAACTGCATCATATGTTGTCAGACTTTGCAGACCGACGTCGAGATTAAACTTCACTCGAAATTCCATCTGCGGCATTTGTTGCAAAAAGATTTCATATGTGCAGTATGCAACAAGATGTTTGACAACCACTTATTGAAAcacgtagaaaaaaataacgtaaatgTTCCCATATGCATTGAATGCATGAAAGCTACTAACGGATCCTCTCCATCGTCCGTGATGCCATCACAGAGCAAACTGTTCGCATGTCTCAAGTGTTCTCAGACATTCGACACGGAGGACGAAATTAAAGCGCACACCACCGAACATTTGATGAACGAAGAGCCCAGCCTCGAATGTCACCTATGCCGCAACGTCCTACCCTCTCCGACCAAACTTCAGGTTCACCTGATCGAGCACAATTTCATGGGAATGGGCCAATACCGCTGCTATGTCTGCTCCTCCGTCTTCACTACAGCTATGGGCCTTCGCACCCACATCATCGCGCACGGACTTAACCATCGACCCTATGAATGTACCGACTGCAAAATGAAGTTCTTCTTCGAGACCGAACTTGAAAACCACCGCTACGTCCATCTGCATCCTAATATGTATACAAAGAATGGTAGCGAATACTTTGAGTGCAAATCTTGCGGTCGATCCTTCAACGACAGCATCTACTACAAGGAGCACGTGCAGAGTTGTCCAATGCCAGCGAAGGACATTGAACAAGCACAGGACACCAAACCAATGATCGAAATTAAGAAGGAAGAATTAAATACCGAATGTGAGCACGAATTAGCTACAATCaacaataataagtaa
Protein Sequence: MLFKGKSSRLEMVIEKIQSNKETTEDTPDDSKPGQGSSPSSSSEQASPASSCQSSLSDTPEAEEPYTMGATATTPYECNICKRAFARSSLLSKHVQTHTEQLQFSCPYCRRLFKHKRSRDRHTKLHTGDKKYKCLHCDSAFARSDHLKIHMKTHDNKKPHQCELCNRGYNTAAALASHQQHHSKQEQRRCGSSASRSSAVSTPSPGNFRCLQCPDTFEKPEHLQNHLQVSHKNISPPASHPNNLLMDASFNILKTAIDLPKIACMYCGKDFLSMNHMYQHIHSEHRAIFNSISQSFTPLPSPVMENLSPKTSRQNSSPTYACDRCTMRFDSPILLQEHIENVHWGPTGLYKYDFTTMSNSSGISNEKSSHSLAATSQSKPTDLSRKRRSENPPDFKLDKRKSSDETTLVSKQTSSPSTGSPYESNDKPCICSYCYAQMPNFKMFLLHMETHVSMSTPSTPLPLSTNNVIGCCPLCGEPARSTLELGRHIFSHAISNVTARCCHCCKKPFDQIDDLQKHLLEAHSQTVYKCSICNDIFETQLALQMHFSNKHSPECKHYRCNLCCDQVFHDRLTAELHVNMKHSIQAPLSSSARNYHHMSRFPEIETRVEFSIYQCPFCQKAFKDEYLQYVHILKEHNEVREGENYLLDSSNRRIPSASPNVAYSKTSSSPDKIDLGKIGNYSCEICNRSDIASEAELTAHKKLHHAKTKVGTLSLQCAYCNEHCKSRNDLENHMKSHQVACGKGKHKCNICDEIFTSNGTLAEHKLTHCKIVAGSSCTQCKAVLLDEQSFYNHQLQHSNTSAINKQNSQISLPANCIICCQTLQTDVEIKLHSKFHLRHLLQKDFICAVCNKMFDNHLLKHVEKNNVNVPICIECMKATNGSSPSSVMPSQSKLFACLKCSQTFDTEDEIKAHTTEHLMNEEPSLECHLCRNVLPSPTKLQVHLIEHNFMGMGQYRCYVCSSVFTTAMGLRTHIIAHGLNHRPYECTDCKMKFFFETELENHRYVHLHPNMYTKNGSEYFECKSCGRSFNDSIYYKEHVQSCPMPAKDIEQAQDTKPMIEIKKEELNTECEHELATINNNK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01059298;
90% Identity: iTF_01059298;
80% Identity: -