Basic Information

Insect: Nicrophorus vespilloides
Gene Symbol: Baz2b
Assembly: GCA_001412225.1
Location: NW:449468-487991[+]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 1.8e-13 5.3e-10 38.2 0.0 4 73 651 721 649 725 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	1.8e-13	5.3e-10	38.2	0.0	4	73	651	721	649	725	0.90

Sequence Information

Coding Sequence: ATGGATAAGGAAAATGGGAAGGGCAACGATGGCAGTTCCGGTTCCAACAAGTTATCAGCTTCCACCGACCCAGCGGCCCTTCTTGATGCGGCCAGCCTCTTTGGTGCGTATTGGCCTAGGGGCGATGCCAGCGCTGCTAACTTGTTtgcagcggcggcggcaggCGGAGCCTACGGCCTGGGGCCGCATCCCTCCATGCCCTTCTCGATGCTGCCCCCAACTTCCGGCCGTGGCGTTTCAGCCTATCCACCAGTATCAAGCGCGGCGGCTTACAGCAATGCATATACAAATACACTGTCGGTGGCGGCGAGCCAAGCCGCTAGCCTAGGCATACCGGCTGCAAGTGCTGCATGGTGGTCCATGGCTTCTCAGCTGGCTGCCCAAGATTATCTGGCAAGACTTCAGGCTTCTGGAATAAACTTCACAGGTCTTGGTAATCCCTCAGACCCTTATGCAGCTGCTCTAGGTCTACCATCACTTTCTGCCGCCCATCACAAGCCCATGAAGAGCTCAAAATCTTCTTCGTCCTCATCACTGCCCAAGGGTTCGAGCCACTCCAATAAAGATAAGTCCAGCTCTCAGAAAAACTCAGCCTCATCGAATAGCAACAAAGCCATCAGCAGTGCAAAGTACTCAAGCAGTAGCAGTGGAGGCAGTCTGACCATACAGCCCAGTCCGAAGATGCACAACTCATGCGGTGCACATTCGAATAACAAATCTAAAGCAAATGACCTCAGGCCTGTGGAAAGCAAAGCCTCCAGTCCCAAGCCACAGACATCCAGTATTTTTACTAGTCCACTAAGTCTAGCCAGTAACTCAGAGAGAATTGATTGCACCACTCCACCGCAAGCAACATCTCAAGGTTCCAACCCATCAACTCCAACTCTGCCTAATAGCATTTTAAGTGCTGCTTTGGAAGGAAGTGGTGATCCAAATTCAATTCTTGGTGGTGTTAGATTGCCGCCAGATACGGAGATAATAAAGTATACGTCATCGATCGTCGGTCCGAAGATCCCTGGAACGACGAACCGTGGCAGGAAGAAGACAATTTCCTTGGATCCACCATTGGTGAGCGTTCATGCGACGCATTCAAGTACGGGAATGTTGATAGAAAGAAACACGAAGCGTCAGAGGCTGGATTCTTCTGGTTCCGATCAGAATAGTACCACTTCGAATTCGGGAAACGATCGGGTGGAGGTAATCAAGCTGCCAGCCACCAACGGAAGTCCTTCCGGTTCGTTCACTAACAGCTTCGGAGAAGGCGAGGCACCTCTGAACCTCTCCTTGAAACCGACAACCAGCAATAACAGTAGTTCCTCATTGAACTCGCTTAGCAATATGTCTGCTAACATTGGTCTGGATAATAGAATATCACGCAGAAAGCCTGGTCCCAAGCCTAGAAAGGTGCTTCAGACTCCTCCAACACTGCCTCCGGGTGCTCCTAGCGCATCGCTGGTACAACTGTTTGCAACGGCAGACTCTCCTCGGCCACCGAGCCGCTCAGACATAGATACACCCTTATGCACTGGAACTACTACGACGGCCAATACTACGATCACATCGTTGCCCGCACCCAATCACAAAGATACTCGCCCCCGAAACCTTGGTAGGGGTGTGAGTAAACCCAAAAAGAACACAGTCGCCTCCCTGCTAGCGCAAAGCAGAGCATtaggAATTAAACCTATGCCCATACTAGATCCCAACGCCTCTATGTCGCAACAAATGTCGCTGCTAAAATCGAACATACTGGCAGCACAACAGTATATAGCAGAAGTAGGAGGTGACgaaaaaacattaaacaaatttttgcaGGAGAAATTCAGGGGTACTCTAAGCGATTCTAGTACGGTCGATGCCTCAACAGATTCTGATAATCTTACAGATTCTAATCAGACTGACTCTGAGCTCGAGTCGGAGGTCGCTTCCGCTAAGAAGCAAAAGCATTACGACGAGCGAGCACTGCGGGTACCTCTTGAGAAAGGGTGGAAAAGGGAAACGATAATAAGAGGTATTACTAAGAACGGCGGAATTAAGGGCGACGTCACTTACGTCGCAACAGACTCCAGCAACAAGTTCAAGCAGATGTCCGACATCACACAATATCTGGACTACCAGAAAAATAACGACTTGTCGAAGGAAAACTTCACGTTCAGCTGTCGTGTCATCCTCGGGGATTATCTTCAAGCGATGCCCCCAGAATTCGTTCAGGAAGGTGGGGAATTTGTTAGGATGACTGAGGACGAGGTTTCCAAACGTTTGGAAGAGCTCAGGGCGGCTATGCGAACAAGTTTACCAGTGGAACAAAGGATAGAAGTTGCTCGGAGGCAGCAGGCAGCGAGGGCTGCAGCAAGACTAGACAGGGAACAGGCGAGGATAGCGCGAGAGATCGAACGGTCAGAAAGACAGGAGGCGGCACGCAGGGACCGCGAAGTTCGCACCCAACAGCTGATGGAGGGCCGCAAGCGTCTAGCGTTCACTTTAGAACAGAAAGTTCAGATAATATGCGAGATCGAGGGCGGCAAAACGAAATCGGACGTGTCCAGAGAACTGGGCTTGGCCAGTTCGACGGTCGCCACGATTTGGAAGAACCGTGACCCCATTATCCGTGCGTACGGTTCGAGTCAATGTGACGAGCATAAATTTGCCCCAACCCTCGTTGACACCGATTCGGCCAAACGAAAAAGGCAGGAGGAGATCGAGAAGCACAAGCAGGAAGAGCAACACAGGAAACAGCAGGAGAGAGAGCTGAAAAGGCAACAGACTGCTATGCTGAAGGAACAGATGTACATACAGGAAATCAGTAAACAGCGAGAGTTGCTCTACACTGTCGAACTGGAGCGGGAGCGCAGGCGGCAACATATGTCATTGGTGAAAGCATTGGAGAATCGTAGGAAGTTGGAGGAGAGAGAACGCAAGAAGCAGCAATTGTTGGCGGAAAAACAGGCGAATAAAGAGAAGAAGATGGAGCAGCGTAGGATCGAATTGGAGATCCTTGCAGAGCTGCGAAAGCCGTGCGAAGATCTGGAACTGGATCAGAAGAGTTTGCCAGAGTACGAGCGGATTCCTGGCCTCAAAATGTCGGGCAAGGCATTTGGTGATACACTCATGGTCTTCGAATTCCTTCACAACTTTGGGGAAACTCTAGGTTTTGATATGGAATCATTGCCAACTCTTGATTCACTTCAAACTGCTTTGCTTAGCAATGATGGATCGGCTGAAGCCGAGGAAGAGTTGCTATCAGTGATGACACATCTTATCGTGTGTGCTATCGAAGATCCCGGAATTCCGAATCCTGCTCGTCATACGACTATACTTGGTCAGAGTCTAAGACAGGCCGACATAACGCACACCAATCTCTCCGAGATCCTCAGGATATACTTGTACGCTAATGCTACTGGTGAAGTTAAAGCGCTTACTGGTGTTTCATTTGAACGTGATAGAGAGAAAAGAGTAGCAGATCATCATCAAAATGACTGTGAGATGCAACAGACTCAATCTGGTAAGAACGCCATATATTATGAGCAATTACATGAGAACGAAACTTGGAAGATGTCAGACATGTTGAAGGACAAGCCTTTCCTTGGGTTATCACCAACAGACAAAGCAGCGATTTTGGCTTTTATTTGCAATGAGTTGCTACAGAACAAGGCAGTGATTCGTCAGATAGAAGGATCCTTGGAAACTGTGGCGCATTCCAGAAAGGAAAAATGGGTAATAGACGCCAAAGTCAGGAAGTTGCGCATGCTTCATAATCGTAAAATTAGAACTGAAGCCATGGAAAAGGCGGCACATATAAAATCTGAAGGAGAAGAGACTGGTATGGATTCTCCAGCTTTGCCCAAAGATGATTTACTCGATGAAGAAGATAATGAAATGAGTGAAAGCGAGAGTGTTGGCACGCAACCCGAAGAAGAGgaagatattaaattatccGGAGAGGAACTGGGAAAAAAGTTGGAGAAAGTTCTTAAAACATCAGATACTCAATTACAGGTTATTAATAGTGCATCCCATCAATTACGAGCGACGTGTTTCGGACAAGACCGCTATTGGCGTCGTTACTGGTCTCTTCCAAAAGCTGGAGGTGTTTTTATAGAAGCCATGGAATCTGCGGATCCAGATATTTTCAGTGAACATCTTCTAAGCGATCAAAAAATGGGTATCAACAGCATTGAAGATATAAAGCATTTAGTTCAAGATGAACCTAATCCGAGCGCAGACAATGAGGTGAGCAATATCGTCAGCAAGCAAGAGATATGCGAGGAGAATACTTGTAAATTAAATGAGGAAACGGACTGCGAAAGTAAAGTTATGGACAACAATGCTAACGAGCATAGGAAGACACCGAATAGGTTAGAAAATGGTGATGTGGAAGACAAACGCGATCATAATTTAGATGAATTACGAAAAAGTGTAGATCGTATCGTTCAAAATCTTGAGAAGAATATTGAATTGGAGAAGGAGAAGGTCGTGGAGAACCATGTAACCATAAAAACTGAGCCAGAGGAGACAAAGAAGTTCAATTTGTTCGAGAAACTTGGTGAATGTATGGAACGCGAGAACACCAAAGAAGTCGATCAGTATGTGAAACCGGAAGTGAAGGAAGAACTTAAAAACGAGATTCTTAACGAATTGAAGACGGAAATTAAAACAGAGATTGAAGAGGATAAACTGGAAAGTGAGAATAGGTGGTTCAGTATTCTGAACAGGGATAGCGTGTCATGTGATACTGTGCATTTAACGGCAGGGAATAGATGGGATAATGGGGTCGGAGCGTGCACTCGCGATAATATTACGGAACTAAAAATACCCGTCTTTCCACCACCAAATTCAAATTGTTCTTATATTGGAAATACGTGCGATAGTCCTGCTCCCTTACAAATCACACCCGAAGAGAGTATTCAGCTGGAGTATATAAAGAAGCATGGTTTGCCGAAGCCCTGTGAGAGGAAAGGTATACCAGTTAACAAAAGATACGGTTGGTGGCGAATTAGTGATGTTGAAGATTTGAAGACGGTATTAGAAAATCTTCATGTACGCGGCGCAAGAGAACGCGAGCTCAAAAGAACATTTGTTTCCACTATGCAAACTATGTACGAACAACCAGGTAGATTGTTCATTGAGGAGGGTCAGAAGGATATGACTGAATTGAGCGCTGATGATTTTGATGTGGTTATGGTGGAAGATGCTCCGCAGCCGGATGAGTCGGGAAGTTGGAACAAAGCAGTAGCTCTACGAGTTGATTTGTTTCTGTTGGAACAAGTGGAAGCTTTAGAGGACAAAGTTGCAAACGCCAGTATGCAAATGAAGGGTTGGAAGGTACCTAATAGAGATACTGAAATACCTTCTTCTGAAGCGGTGAACATAGCGAAGGAGAGGTTGGCATCTTTGGAGGCAGCTATAGAGAGGCGATATTTGAAACCACCGTTGGGTGTCAATACGGGTGATCCCAATTTGGCTGCTATTGCGCAGGAGGCAGCCGGAGCTCCGACTCCGGCTCAGCCCATTCCCGGACCTGATGAGGTTCCAAAAGGTCTGGCCGTGTGGCGCGAGGCCATCAACCGTTCTCAGACATCTGCCCAGCTGGCGATGTGTCTGTACACCCTCGAGGCGTCCATCGCTTGGGACAAGAGTATCATGAAAGCTGTGAGCCCCTCTCTAGTCTTTAATAAACAGAGAGCCCGCAAATATAACAGCAAGCTGAGTAACTGCCAATTCTGCAATAGTGGAGACAACGAGGATAAGTTACTGTTATGCGACAGTTGCGACAAAGGGTATCATACGTACTGCTTCAAACCAAAACTGGATACTATTCCAGACGGTGACTGGTATTGTCATGAGTGTATGAATAAAGCTACCGGCGAAAAAAACTGTATCGTATGTGGTAAAAAACAATCTTTATCAAATACCAGACTAGTAGTGTGTGAGTTGTGTCCAAGAGCTTACCACACTGACTGCATCCGGCCGCAATTGAACAAAGTGCCTCGTGGGAAGTGGTATTGCGTCAATTGCATTTCGAAGAAGCCCCAGAAGCGGGCTATCAAGAAGCAAACTAAAGTTGCTAGGGAGAGTGAGTCTTCCGAGCAACCTCCATTAAGtcCAGCACCGTCACATAGTTCGGCAACAACCAATGAGGACATCACTGCccaacaaaatgtaaatatttgtaaccaGAGCGACGTGTCCAACTCCAGCATCCAGAATGCCGGTTCCCCAATTAaccagcagcaacagcaacagcagcaacaacagcaacagacGGCAGCGGTATCTAGAAAAGACAAGGTTTCCAAGAAGGTGATAAAAGAGCTGGCACCGTGCAAGGCAATCCTCGAGGACCTCGAGTGTCACGACGATGCCTGGCCGTTTCTTCTTCCAGTGAACACCAAACAATTTCCCACCTACAAAAAGATTATTAAGAGTCCGATGGATCTGAGTACAATTAAGAAACGCTTATTGGATTACACttataaatcgAAGGAGGACTTTTGCACAGACGTACGACAAATATTCAACAATTGCGAGACGTTCAACGAGGACGACAGTCCAGTGGGCAAAGCTGGACACTGTATGAGGCAGTTCTTTGAGGCTCGCTGGAACGAATTGTGCTTGTCGCATAGTTGA
Protein Sequence: MDKENGKGNDGSSGSNKLSASTDPAALLDAASLFGAYWPRGDASAANLFAAAAAGGAYGLGPHPSMPFSMLPPTSGRGVSAYPPVSSAAAYSNAYTNTLSVAASQAASLGIPAASAAWWSMASQLAAQDYLARLQASGINFTGLGNPSDPYAAALGLPSLSAAHHKPMKSSKSSSSSSLPKGSSHSNKDKSSSQKNSASSNSNKAISSAKYSSSSSGGSLTIQPSPKMHNSCGAHSNNKSKANDLRPVESKASSPKPQTSSIFTSPLSLASNSERIDCTTPPQATSQGSNPSTPTLPNSILSAALEGSGDPNSILGGVRLPPDTEIIKYTSSIVGPKIPGTTNRGRKKTISLDPPLVSVHATHSSTGMLIERNTKRQRLDSSGSDQNSTTSNSGNDRVEVIKLPATNGSPSGSFTNSFGEGEAPLNLSLKPTTSNNSSSSLNSLSNMSANIGLDNRISRRKPGPKPRKVLQTPPTLPPGAPSASLVQLFATADSPRPPSRSDIDTPLCTGTTTTANTTITSLPAPNHKDTRPRNLGRGVSKPKKNTVASLLAQSRALGIKPMPILDPNASMSQQMSLLKSNILAAQQYIAEVGGDEKTLNKFLQEKFRGTLSDSSTVDASTDSDNLTDSNQTDSELESEVASAKKQKHYDERALRVPLEKGWKRETIIRGITKNGGIKGDVTYVATDSSNKFKQMSDITQYLDYQKNNDLSKENFTFSCRVILGDYLQAMPPEFVQEGGEFVRMTEDEVSKRLEELRAAMRTSLPVEQRIEVARRQQAARAAARLDREQARIAREIERSERQEAARRDREVRTQQLMEGRKRLAFTLEQKVQIICEIEGGKTKSDVSRELGLASSTVATIWKNRDPIIRAYGSSQCDEHKFAPTLVDTDSAKRKRQEEIEKHKQEEQHRKQQERELKRQQTAMLKEQMYIQEISKQRELLYTVELERERRRQHMSLVKALENRRKLEERERKKQQLLAEKQANKEKKMEQRRIELEILAELRKPCEDLELDQKSLPEYERIPGLKMSGKAFGDTLMVFEFLHNFGETLGFDMESLPTLDSLQTALLSNDGSAEAEEELLSVMTHLIVCAIEDPGIPNPARHTTILGQSLRQADITHTNLSEILRIYLYANATGEVKALTGVSFERDREKRVADHHQNDCEMQQTQSGKNAIYYEQLHENETWKMSDMLKDKPFLGLSPTDKAAILAFICNELLQNKAVIRQIEGSLETVAHSRKEKWVIDAKVRKLRMLHNRKIRTEAMEKAAHIKSEGEETGMDSPALPKDDLLDEEDNEMSESESVGTQPEEEEDIKLSGEELGKKLEKVLKTSDTQLQVINSASHQLRATCFGQDRYWRRYWSLPKAGGVFIEAMESADPDIFSEHLLSDQKMGINSIEDIKHLVQDEPNPSADNEVSNIVSKQEICEENTCKLNEETDCESKVMDNNANEHRKTPNRLENGDVEDKRDHNLDELRKSVDRIVQNLEKNIELEKEKVVENHVTIKTEPEETKKFNLFEKLGECMERENTKEVDQYVKPEVKEELKNEILNELKTEIKTEIEEDKLESENRWFSILNRDSVSCDTVHLTAGNRWDNGVGACTRDNITELKIPVFPPPNSNCSYIGNTCDSPAPLQITPEESIQLEYIKKHGLPKPCERKGIPVNKRYGWWRISDVEDLKTVLENLHVRGARERELKRTFVSTMQTMYEQPGRLFIEEGQKDMTELSADDFDVVMVEDAPQPDESGSWNKAVALRVDLFLLEQVEALEDKVANASMQMKGWKVPNRDTEIPSSEAVNIAKERLASLEAAIERRYLKPPLGVNTGDPNLAAIAQEAAGAPTPAQPIPGPDEVPKGLAVWREAINRSQTSAQLAMCLYTLEASIAWDKSIMKAVSPSLVFNKQRARKYNSKLSNCQFCNSGDNEDKLLLCDSCDKGYHTYCFKPKLDTIPDGDWYCHECMNKATGEKNCIVCGKKQSLSNTRLVVCELCPRAYHTDCIRPQLNKVPRGKWYCVNCISKKPQKRAIKKQTKVARESESSEQPPLSPAPSHSSATTNEDITAQQNVNICNQSDVSNSSIQNAGSPINQQQQQQQQQQQQTAAVSRKDKVSKKVIKELAPCKAILEDLECHDDAWPFLLPVNTKQFPTYKKIIKSPMDLSTIKKRLLDYTYKSKEDFCTDVRQIFNNCETFNEDDSPVGKAGHCMRQFFEARWNELCLSHS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01400379;
90% Identity: iTF_01058419;
80% Identity: -