Nmel015273.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Netelia melanura
Gene Symbol
topi
Assembly
GCA_964007305.1
Location
OZ023257.1:8837361-8839864[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 1.2 1.4e+02 3.9 0.3 1 12 258 269 258 276 0.84
2 16 3.8 4.4e+02 2.3 1.4 2 11 287 296 286 309 0.77
3 16 0.00057 0.066 14.3 0.4 2 21 316 335 315 336 0.93
4 16 1.9e-05 0.0022 18.9 0.8 1 23 343 365 343 365 0.97
5 16 3e-06 0.00034 21.5 2.8 1 23 371 393 371 393 0.98
6 16 0.73 85 4.5 1.0 2 23 405 427 404 427 0.87
7 16 0.0048 0.55 11.4 2.9 1 23 443 465 443 465 0.98
8 16 0.016 1.9 9.7 0.1 1 23 471 493 471 493 0.95
9 16 0.046 5.4 8.3 2.4 1 23 503 526 503 527 0.95
10 16 0.005 0.58 11.3 0.4 1 21 542 562 542 563 0.93
11 16 0.013 1.5 10.0 0.3 1 23 568 590 568 590 0.98
12 16 2.3e-06 0.00027 21.8 3.1 1 23 596 618 596 618 0.98
13 16 0.00015 0.017 16.1 0.4 1 23 624 647 624 647 0.97
14 16 0.056 6.5 8.0 0.7 1 23 653 675 653 675 0.89
15 16 3.7e-07 4.3e-05 24.3 2.2 1 23 681 703 681 703 0.99
16 16 7e-06 0.00081 20.3 4.9 1 23 709 732 709 732 0.96

Sequence Information

Coding Sequence
ATGACAAGCACAGTCAAAGCCGATTCGATAAGTACGACATTGAGCGATACGGACGATTACATGGATGATGTTGAGGATGCAAGTGGTAGATTGTCACAGGATGATCCTCTATCTACACACATCATCGAGTCGGAAGCTAAATCAGGATCGAATAGTGATGATGCACGCGTGGCACTTTGCCGTTTGTGCGCCGGCCGAGCAATCAATCCTATCTACATTTATTCAGATTTTGGTGAATCAATGAAGCTTGCACACAAAATAAATACATGCTTGAGTGTAAAGATACGAAAAACGGACCCTCTACCCAAACAATTGTGCTGTGTCTGCGTAGAGAAGATCAATTGGTGTGATTCTTTCGATGAACAATGTATAAAAGCAGAGGAGACTCTCGAAACGATGCTTCGAGATGAAAAGGATAATTCGGAAATATCGGAAAACATTGTTCCGGATATTTCCTGCACCGAGGAATCTTGCCCACTGTGTATAGATGGTCATATGCTCACAACTTGTTTGAACGATCCGACAAGTACAAGTAATACGCAATCAGATTTATATGATGGCGATATCGTTATGGAGAGTAGTGACGAGGAGAAGATCTTGGGCAATTTTGATGAAGAGAAAGGTCTAGCTGACAGTAATTCCATACATCTTAAGGGCTTCAGTAATACACAGCATTATCTCAAATGTGGAGCTTGCATGAATCTCTATCGTACGAAAGAGAGTCTCGAGGTTCACAAGTGCAAGCCCAACATCCAAAGCACTTCGAGACCCTACAAATGCGTCATGTGCGACGCGACGTTTCCCTTCGAGGAACGTCTTAATTTTCACTGCCAATTTCATAATGGTGCCAAGGAGCTTTACTGTCCGATATGCAAGATTACATTTGGCAAGGAGTTAAAGCATTTTTATCACTATAAGCGTTACCATTGCGAGGACAAAAGCGTGTCTTGTCTCCAATGCGGGAAGCTGTTCTCGAGTCAGCAAGAATTACGAATACACATTTGTGTCGATGGTAAAACTCGTCCACACGTTTGCGACATCTGTAACAAAGGATTTTCCGACGGTTACACTCTCAAGCGTCACGTCGTGACTCATTTGCCCGAAAAACCGTATAAATGTTCGCAATGTTCAAAGAGTTTTACCCAAAAATCGCGTCTGAACAAACACGTCGCCAGTCATGGAATTGTGATCGACAATTCCCAGATCGCCTGGAAGTGCGTCCAATGTGGTGAAATTTTCGAGACTTGCAACGAGGCTGACTCTCACAATCGCCAAAAacacgatggaaaaataagcCTCGTCGAGGAACTATCAACATCGAAGATTTATCATTGTGAATTTTGTAACAGTTATTTCAACGATGTGGAGAATCTCAGAGACCATCAGAATCGTCATGTTGCAGAGAAACCGTACACGTGTAATATATGTAACGCAGTGTATAAATCATACGCCGAAGCTGTTTTACACTGGAAGGAACATCCTCGAGTATTTCGAGTGGCAACGGCCTATCTGTGCGACGTATGCGGCAAAGACATGAAGGAAATGTCTCTTTTGTACAAGCATAGACGTAAAAGACATCATGTAATGCCACGGAAATCCGAGATTGAGGATTCAAGTCTAAAGTACGTTTGTGAGTTATGCAGCAAGTGTTTCGAAAAAAGCGAAGAAATACGTGTTCACGGACGTGATCAATGCTCGAAATTTCCTTGCGACATATGCGGCAGTCTGTTGCCAACAGCAAATTCGTTGCACGCTCACAAGAGAAGACACAGCGGGCTGCGACCTTATGTTTGCAATATTTGTGGCAAAAGTTATACCCAATCTAGTCACATGTGGACTCACAAGAGATTTCACATGGGGGTTAAACCGTACGCGTGTGAATATTGCGATCAGAGATTTACGATAAAGCCCGATCTTGCCGATcacacgagaaaaaaacatacgCGTGAACGACCTTTCAAATGTGATGTCTGCAACAAAGCTTTTCTCACCGGGTCTGTCTTCTATCAGCACCGATTAATACATCGTGGTGACAGACGATACAAGTGTCATTATTGTGAAAAAGCTTTTACCAGAACCGAAGCTCTCAATAATCACATTAAGATACATACGGGCGAGAAACCCCACGCGTGCGACGTGTGTGGTAGATGTTTCAGGCAAAAGGGTGACATGCGAAAGCATCGACGAACGCAACATACCGTTCCTAAAGAAGAAATGCCACAATTAGGATGA
Protein Sequence
MTSTVKADSISTTLSDTDDYMDDVEDASGRLSQDDPLSTHIIESEAKSGSNSDDARVALCRLCAGRAINPIYIYSDFGESMKLAHKINTCLSVKIRKTDPLPKQLCCVCVEKINWCDSFDEQCIKAEETLETMLRDEKDNSEISENIVPDISCTEESCPLCIDGHMLTTCLNDPTSTSNTQSDLYDGDIVMESSDEEKILGNFDEEKGLADSNSIHLKGFSNTQHYLKCGACMNLYRTKESLEVHKCKPNIQSTSRPYKCVMCDATFPFEERLNFHCQFHNGAKELYCPICKITFGKELKHFYHYKRYHCEDKSVSCLQCGKLFSSQQELRIHICVDGKTRPHVCDICNKGFSDGYTLKRHVVTHLPEKPYKCSQCSKSFTQKSRLNKHVASHGIVIDNSQIAWKCVQCGEIFETCNEADSHNRQKHDGKISLVEELSTSKIYHCEFCNSYFNDVENLRDHQNRHVAEKPYTCNICNAVYKSYAEAVLHWKEHPRVFRVATAYLCDVCGKDMKEMSLLYKHRRKRHHVMPRKSEIEDSSLKYVCELCSKCFEKSEEIRVHGRDQCSKFPCDICGSLLPTANSLHAHKRRHSGLRPYVCNICGKSYTQSSHMWTHKRFHMGVKPYACEYCDQRFTIKPDLADHTRKKHTRERPFKCDVCNKAFLTGSVFYQHRLIHRGDRRYKCHYCEKAFTRTEALNNHIKIHTGEKPHACDVCGRCFRQKGDMRKHRRTQHTVPKEEMPQLG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00629316;
90% Identity
iTF_01057096;
80% Identity
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