Dlut015519.1
Basic Information
- Insect
- Dyspetes luteomarginatus
- Gene Symbol
- topi
- Assembly
- GCA_963669185.1
- Location
- OY769911.1:15927358-15930091[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 15 2.5 2e+02 2.8 1.2 2 13 286 297 285 308 0.72 2 15 0.0045 0.37 11.5 0.4 2 21 315 334 314 335 0.93 3 15 1.1e-05 0.00088 19.7 0.9 1 23 342 364 342 364 0.96 4 15 4.4e-06 0.00036 20.9 2.0 1 23 370 392 370 392 0.95 5 15 0.24 20 6.0 1.0 2 23 404 426 403 426 0.93 6 15 0.021 1.7 9.3 2.8 1 23 442 464 442 464 0.98 7 15 0.081 6.6 7.5 0.1 1 23 470 492 470 492 0.94 8 15 0.075 6.1 7.6 0.9 1 23 502 526 502 526 0.90 9 15 0.054 4.4 8.0 0.0 1 20 541 560 541 562 0.88 10 15 0.013 1 10.0 0.3 1 23 567 589 567 589 0.98 11 15 2.3e-06 0.00018 21.8 3.1 1 23 595 617 595 617 0.98 12 15 0.0002 0.016 15.7 0.6 1 23 623 646 623 646 0.97 13 15 0.055 4.5 8.0 0.7 1 23 652 674 652 674 0.89 14 15 3.6e-07 2.9e-05 24.3 2.2 1 23 682 704 682 704 0.99 15 15 6.9e-06 0.00056 20.3 4.9 1 23 710 733 710 733 0.96
Sequence Information
- Coding Sequence
- atgacgagtacAGTCAAAGCCGATTCGATCAGCACATCACTGAGCGATAGGGAGGATTACATGGATGATGGGGAGGATGCAAGTATAATATGGTCACAGGACGATCCATTGTCGACGAGTGAAGTTATCGAACAGGAAGGTAAATCAGGATCAAACGGTGATAACGAGACAACAGCAATTTGCCGATTGTGCGCCGGTCAAGCGATCAATCCCGTTTATATTTATTCCGAATTTGGAGAATCGATGAAACTCGCACACAAAATCAATAATTGCTTGAGTGTaaagattaaaaaaacGGATCCTCTTCCAAAGCAATTGTGCTATATCTGCGTCGAGAAGATTAATTGGTGTGATAATTTCGACGTGCAATGTATGAAAGCAGAGGAGACCCTTAAAATAATGTTGCAAGATGATCAAGAAAGCTCGGAAATACCGGAAATTATGATACCGGATATTCCCTGCACCGAAGAGTCATGCCCACTCTGTACGGAGGGTCACATGTTAGCTTCTAGTCTGAATGAACCGACGAGCTTGCAATCAGATTTGTACGATAGCGATATAGTTATGGAGAGCAgcgacgaggaaaaaatattgagcaaTTTGAATGAGGATAAACGGGACAACCCTGACGGAAATTCCATTCGTCTACGATGTCTCGGCAATAGCCAGCAATATCTCAAATGCGGTGCATGCATGAATCTTTATCACACGAAAGAAAGTTTGAATGCGCACAAGTGCAAGCCAAATATACAAACGACCTCAAGACCCTACAAATGTCTTGCATGCGATGCAAATTTTCCCTTCGAGGAGcgtttaaattttcactctcAATTTCACGTTGGTGCCAAAGAGCTTTACTGTCCCATATGCAAGATAACATTTGGCaaagaattgaaatatttttttcactacaaGCGTTATCACTGCGAGGATAAGAGCGTTTCTTGTCTTCAATGCggcaaattatttcaatcgcAGCAAGAATTACGAGTACACATTTGCATCGATGGTAAAACACGACCACACATTTGTGATATTTGCAACAAAGGATTTACCGATGGTTACACCCTTAAGCGTCACATTGTGACGCATTTGCCAGAAAAGCCCTACAAGTGCTCGCAATGCTCGAAGAGCTTTACCCAAAAATCACGTCTCAATAAGCACGTAGCTGGTCATGGtgtgataattgaaaattcacagATAGCCTGGAAATGCGTTCAATGCGGTGAAATATTTGAGACATGCAACGAGGCCGATAATCACAATCGTAAATATCACGATGGCAAGATAAGCCTCATTGAGGAATTATCAACATCGAAGATATATCATTGTGAATTTTGCAACAGTTATTACAACGACATTGAAAATCTGAGAGATCATCAGAATCGTCATATTGCGGAAAAACCATATACGTGCAATATTTGCAAcaatatttatcgatcatACGCCGAGGCTGTTTTACACTGGAAGGAACATCCACGATCATTTCGCGTTGCGATTGCTTATCTTTGCGATGTTTGTGGCAAAGACATGAAAGAAATGTCGCTCTTGTACAAGcatcgaagaaaaagaaatcacATGACGCCCCGTAAATCGGAAATTGATAATACAAATGAGAAATACATTTGCGAATTGTGCGGTAaggattttgataaaattgaggAAATACGAGTACACGGACGTGATCAATGCTCAAAATTTCCATGCGATATTTGCGGCAGTCTTTTGCCGACCGCTAATTCTTTGCATGCACATAAAAGAAGACACAGCGGCTTGCGTCCTTATGTTTGCAATATTTGTGGCAAAAGTTATACGCAATCTAGTCATATGTGGACACACAAGAGATTTCACATGGGTGTTAAGCCTTACGCTTGTCAATATTGCGATCAAAGATTTACGATAAAGCCTGATCTTGCAGATCATACGAGGAAGAAACATACGCGCGAACGACCTTTCAAATGTGATGTTTGCAACAAAGCTTTTCTCACCGGATCGGTATTTTACCAACATCGACTTATTCATCGTGGCGCCACTGGCAGACGCTACAAATGTCATTATTGCGAAAAAGCTTTTACGAGAACGGAAGCTCTGAATAATCATATTAAAATACACACGGGCGAAAAGCCTCATGCGTGCGATGTGTGTGGCAGATGTTTTAGGCAAAAGGGCGATATGAGAAAACACAGACGAACGCAACATGCCATTGCTAAAGAAGAAACACCTTGA
- Protein Sequence
- MTSTVKADSISTSLSDREDYMDDGEDASIIWSQDDPLSTSEVIEQEGKSGSNGDNETTAICRLCAGQAINPVYIYSEFGESMKLAHKINNCLSVKIKKTDPLPKQLCYICVEKINWCDNFDVQCMKAEETLKIMLQDDQESSEIPEIMIPDIPCTEESCPLCTEGHMLASSLNEPTSLQSDLYDSDIVMESSDEEKILSNLNEDKRDNPDGNSIRLRCLGNSQQYLKCGACMNLYHTKESLNAHKCKPNIQTTSRPYKCLACDANFPFEERLNFHSQFHVGAKELYCPICKITFGKELKYFFHYKRYHCEDKSVSCLQCGKLFQSQQELRVHICIDGKTRPHICDICNKGFTDGYTLKRHIVTHLPEKPYKCSQCSKSFTQKSRLNKHVAGHGVIIENSQIAWKCVQCGEIFETCNEADNHNRKYHDGKISLIEELSTSKIYHCEFCNSYYNDIENLRDHQNRHIAEKPYTCNICNNIYRSYAEAVLHWKEHPRSFRVAIAYLCDVCGKDMKEMSLLYKHRRKRNHMTPRKSEIDNTNEKYICELCGKDFDKIEEIRVHGRDQCSKFPCDICGSLLPTANSLHAHKRRHSGLRPYVCNICGKSYTQSSHMWTHKRFHMGVKPYACQYCDQRFTIKPDLADHTRKKHTRERPFKCDVCNKAFLTGSVFYQHRLIHRGATGRRYKCHYCEKAFTRTEALNNHIKIHTGEKPHACDVCGRCFRQKGDMRKHRRTQHAIAKEETP
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01056272; iTF_01057096; iTF_01057850; iTF_01129530;
- 90% Identity
- -
- 80% Identity
- -