Ncom011679.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Neria commutata
Gene Symbol
KLHL17
Assembly
GCA_963457695.1
Location
OY735247.1:8614856-8623526[+]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 1.1e-33 3.5e-31 108.1 0.2 2 109 63 168 62 169 0.97

Sequence Information

Coding Sequence
ATGTTTTTGCCTGTCAAATCAAATCTTTCCACCGAAAACGGCGGCAACACTGAAGACGTTACCACCACCAGCAACAATTCCACACAAACGCCCAGCGATCTGAGTCCACCGGGTCCCAATGAGGAAGTGCTGCCGCAGGCGCATCATCAAAATCCCGGCCATTGTATTGCCTCGTTCGCTGCCATCAATCAGATGCGCAACAATGCGCAGcTGTGCGATGTTACTCTGGAAGTTGGCGGCGAAACGTTACACGCTCACAAAGTGGTGCTGGCCTCCGTCTCGCCCTACTTCTATGCCATGTTCAACGATGACATGCTGGAGCGCAGCCAGGGTATCGTGCGGCTGCACGACGTGGATGTGACCGCGCTGCGGCAACTCATCGATTACACCTACACCGGCGAGATCACCATCACGGAGGAGAATGTGCAAGTGCTGCTGCCTGTCTCGAGCTTGCTGCAGATACATTCGGTGCGCGAGGCCTGCTGCAAGTTTCTGCTGCGCCAGCTGCATCCCTCCAACTGCCTGGGCATACGCAGCTTCGCGGACGCACACTCCTGCAAGGAGCTGCACACACGCTCCCACAAATACGCGCTGCAAAACTTTCAACAGGTCGTGGGAACCGAAgagtttctgctgctgccctTCGAAGAGGTTAAGGATCTAATATCAAACAGTCAGCTGAACATCTGCTCCGAGGAGAAGGTATTCGTCGCCGTACTCAACTGGGTGAAGCACGACCTCGGCGAGCGGCAGAATCACATAGCGGAGCTGATGAGTCACGTGCGCCTGCCGCTGGTGAGTCGCGACTTCCTGATGACGTGCGTAGAAACGGAGCCGCTCATACGGGATGACTGCAAGGAGCTGTTGCTGGAGGCCATGAAGTACCACCTGCTGCCCGAGCAGCGCAGTCTGATGAGCAGCCAGCGCACGGTGGAGCGCCGCCCGGACGGCATGAAGCCGTATGTATTCGCCGTAGGCGGCGGCAGCCTCTTCGCCATACACAACGAGTGCGAGGTGTACAATCCGCGCAGCAACTCCTGGACGCCGATAGCGCCGATGCTGTGGCGGCGCTCGCGCTCCGGCGTCACGGCGCTGCACAAGCAGCTGTACGTGGTTGGCGGCTATGACGGCGTCAGTGATCTCGCCACAGCTGAATACTACAATCCGCTGGCGAACAAGTGGACCAACATCACGCCGATGGGCACGAAGCGCTCCTGCCTGGGCATCTGCGCCTTCGACGGGCTGCTGTATGTGTGCGGCGGCTACGACGGCGCCTCCTGTCTGAGTAGCATGGAGCGCTACGATCCGCTGACGGGCATTTGGAGCTCCTGTCCGGCGATGAGCACGCGTCGGCGCTACTGCCGCTTGGCCGTGCTGGACAACTGCATCTATTCGCTGGGTGGCTTCGACTCCACCAATTACCAGTCGAGCGTGGAGCGGTTTGATCCGCGCGTGGGTCGCTGGTGCCCCGTGCCGAGCATGACAGCGCGTCGCAGCAGCTGCGGCGTGGCCTCCAACGACGGCTATCTCTACTGCATCGGCGGCAACGACGGCACCATGTGCATGTCCAGCGGCGAGCGCTTCAACTTGCGGCGCAATGTGTGGGAGCCCATAGCGGCCATGCACTCGAGAAGATCGACGCACGAAGTGGTCGAGGTGGACGGCTCGCTGTACGCGCTCGGCGGCAACGATGGCTCCTCATCTCTCAACTCCGTGGAACGCTACGACACGCGCCTCAACAAGTGGACCATTGTCAATTCGATGGTGGCGCGGCGCAGCTCCGTGGGCGCAGCCGTGCTGGAGTGCTTTCACCTCGAGCGTGGCCTGGTGCAGACGACGAACTTATGA
Protein Sequence
MFLPVKSNLSTENGGNTEDVTTTSNNSTQTPSDLSPPGPNEEVLPQAHHQNPGHCIASFAAINQMRNNAQLCDVTLEVGGETLHAHKVVLASVSPYFYAMFNDDMLERSQGIVRLHDVDVTALRQLIDYTYTGEITITEENVQVLLPVSSLLQIHSVREACCKFLLRQLHPSNCLGIRSFADAHSCKELHTRSHKYALQNFQQVVGTEEFLLLPFEEVKDLISNSQLNICSEEKVFVAVLNWVKHDLGERQNHIAELMSHVRLPLVSRDFLMTCVETEPLIRDDCKELLLEAMKYHLLPEQRSLMSSQRTVERRPDGMKPYVFAVGGGSLFAIHNECEVYNPRSNSWTPIAPMLWRRSRSGVTALHKQLYVVGGYDGVSDLATAEYYNPLANKWTNITPMGTKRSCLGICAFDGLLYVCGGYDGASCLSSMERYDPLTGIWSSCPAMSTRRRYCRLAVLDNCIYSLGGFDSTNYQSSVERFDPRVGRWCPVPSMTARRSSCGVASNDGYLYCIGGNDGTMCMSSGERFNLRRNVWEPIAAMHSRRSTHEVVEVDGSLYALGGNDGSSSLNSVERYDTRLNKWTIVNSMVARRSSVGAAVLECFHLERGLVQTTNL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00352554;
90% Identity
iTF_00352554; iTF_00257921; iTF_00972289; iTF_00797826; iTF_00366572; iTF_01415116; iTF_01486289; iTF_01023092; iTF_01426740; iTF_00624823; iTF_00351928; iTF_01181248; iTF_01200960; iTF_01404992; iTF_00337698; iTF_00724869; iTF_00426465; iTF_00693922; iTF_00664163; iTF_00664931; iTF_01356996; iTF_01521957; iTF_01396614; iTF_00314409; iTF_01116521; iTF_00389707; iTF_00188236; iTF_00984332; iTF_01541516; iTF_00976592; iTF_01542288; iTF_01300977; iTF_00311890; iTF_01223506; iTF_00313555; iTF_00894036; iTF_00974804; iTF_00316053; iTF_00335158; iTF_00991894; iTF_00312695; iTF_00315257; iTF_01212057; iTF_00311130; iTF_01044794; iTF_01051258; iTF_00665755; iTF_01300125; iTF_00694751; iTF_00240832; iTF_00310336; iTF_01318336; iTF_00671012; iTF_00671650; iTF_00672276; iTF_00812871; iTF_00672906; iTF_00160811; iTF_00643304; iTF_00363337; iTF_01224682; iTF_00644212; iTF_01297590; iTF_01254030; iTF_00999727; iTF_00322636; iTF_00793591; iTF_01375928; iTF_01540439; iTF_00118791; iTF_00424743; iTF_01431019; iTF_00202700; iTF_01432144; iTF_00176497; iTF_01519418; iTF_01049759; iTF_00203648; iTF_01194481; iTF_00741953; iTF_01399556; iTF_00045415; iTF_01174343; iTF_01376711; iTF_00350249; iTF_01074569; iTF_01259279; iTF_00899696; iTF_01374160; iTF_01138102; iTF_01398582; iTF_00258967; iTF_00760183; iTF_00199960; iTF_00655385; iTF_01237753; iTF_01109403; iTF_01261083; iTF_00900702; iTF_01236798; iTF_01427550; iTF_00922175; iTF_00259840; iTF_01177024; iTF_01313074; iTF_01313889; iTF_00746786; iTF_00679588; iTF_00892837; iTF_00748294; iTF_00749766; iTF_00749031; iTF_01165608; iTF_01375017; iTF_00817515; iTF_01019499; iTF_00750540; iTF_00975692; iTF_01201710; iTF_00371152; iTF_00816624; iTF_00716788; iTF_01231669; iTF_01231670; iTF_01235831; iTF_01315575; iTF_00997816; iTF_00747546; iTF_01175194; iTF_01378459; iTF_01470588; iTF_00979414; iTF_01132988;
80% Identity
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