Ngue032622.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Nephrotoma guestfalica
Gene Symbol
-
Assembly
GCA_963691935.1
Location
OY829914.1:165542966-165553027[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 8.9e-05 0.017 17.3 0.2 1 23 370 392 370 392 0.94
2 12 0.00034 0.067 15.5 1.7 1 23 401 423 401 423 0.98
3 12 0.00044 0.086 15.2 0.5 2 23 431 452 430 452 0.97
4 12 8.9e-07 0.00017 23.6 1.9 1 23 458 480 458 480 0.99
5 12 0.00011 0.021 17.1 1.4 1 23 487 509 487 509 0.98
6 12 1.5e-05 0.0029 19.8 1.7 1 23 515 537 515 537 0.96
7 12 5.6e-05 0.011 18.0 0.3 1 23 543 565 543 565 0.98
8 12 1.8e-05 0.0036 19.5 0.9 1 23 571 594 571 594 0.96
9 12 0.00018 0.036 16.3 2.1 1 23 600 623 600 623 0.94
10 12 0.00021 0.042 16.1 1.9 1 23 629 651 629 651 0.98
11 12 0.00013 0.026 16.8 1.5 1 23 657 679 657 679 0.97
12 12 0.00058 0.11 14.8 0.1 1 22 685 706 685 709 0.92

Sequence Information

Coding Sequence
ATGCGTCGAGCAAAAAAAACTATTGACAACAATAATACAAGCGGGGCTGTTAGGATTAATCCCGAATATGACGAGGCCATTGAAAAGATTAGGTCGATTGATGATTCTTTAGAGCCGCCTCGTCTATATTTTCCAGGAAAAACTCCAATTAATGATTTGTCACCATCATTCATTCTCTCTCAAATATTGAACCGGCCTCTGGGAAGTGATACCGTTCATTCTGATTCGCTgtgtcaaaattgttttaaattatgtttagaatttgaagaattggaacaGCGTTTAGTTGAAATCCGCCTTGAATTCATTCGTAATTTTAACAATACAGCAATCACCTACAATTTAGAACCAGTTGAACTTGAAGACGATGAAGTCGAAGATGATAATCTAGCCGATGAAAATTTGGTGGAAGAGGATGATGAATGTGATGAGAATGATGGCGATGAAGAGCAAACGCAGGAAATTGTCCACGATGAAACTCGTGAAGATGAAATCCTAGAAGATCCGTTGGAAAAGATTACACGTCACCATCAGGagattttggaacaatatgaaaCACCTGAGGCTAATGAAGCGGAAAAAGAAACAAGAGTCATACTTTTAGATAATTTGCCCCCAAGCTTAGTGCAGGATGGACACCATAGTAACACTGCAACATATTCGATTGATGCAACTCACTTTCGGGAAGAATACCTTAGCGAAGAAAATCATAATATGGTCGAGGTCGTTGCGGAATCAGAGGATTACGTCGATTTAATTGTGCATGAAACTCAAATGTCACACGATGAAAATTCGTATGAGAGTGGAATTGTTAAGGATAATTCAAAATCATCCGAAAATAGCCAGGATAGTAATCGAAATCATCTGTTCCAAATCAAAGTCGAACAAAGTGATAATAGCGAAAGTGCGTTCAGTGttccattaaataaaacaaaaggacgaaaaactaataaaacagaAAAGGATGCAATTGTGTTGAGTACAAGCGAGATTTTCACCCGAGAAGGCGATTCCTACGTTTGCCAATTATGTACagataaaagtttaattatttacgaTGGGCGGACCATCGGAATTCATTTAAAATCGATTCacgatattaaaatttacttatgtGACATATGTGGCCAAGACTTTCGCAAGCGAAGCGAGCTCACAGAACATCTAGATGAGCATGTATCGTCGACAGAGGACGGGTTCTTCACCTGTGATTTATGTAATAGAGAATTTAACAATTTACGTCTCTTTCGAATACACAAACGTATACATTACACGAACTCAAAGTCGTGGCCTTgtacaaaatgtaataaaaagtaTGGATCAAAAAATTTGCTGGACGAGCATATGAATATGCATACAGGGAAACGACCCTATAAATGTGGTCATTGCGACAAAGATTTTGCATCTAAATATACCCTATCAGCCCATATGAAAATTCATTCCGATCGTCCACGGCCGTTTAATTGTCGAACATGTGGCAAATCATTTTATAGTGGgcaaaatttaatacaacacGAAAAGACGCACACCGGTTTGCGACCACATGTATGTGAAGCATGCGATAAATCTTTTAGTACGCAgcataatttggaagttcataAAATTGTACATACCGGGTTTAAGCCATTTATTTGTAGGACTTGTGGCAAAGCATTTGCACGGCGAGCTGAAATTAAGGATCACGAACGAACGCACACTGGTGAAAAGCCGTTCAAATGTGATTTATGTAGTGCAAGTTTTGCACAGCGATCAAATCTGCAGTCTCACAAAAGGGCTACGCATTTAGATGATAAACGATATCAATGTGACATTTGTGATCGCCGGTTTAAAAGACGACGATTATTAGATTACCATAAGAAAGCCACCCATACAGGTGAACGACCATTTGAATGTCGACTCTGTTCGGCCACATTTGTTTACCCCGAACACTATAAAAAACACTTGCGCATACACTCCGGCCTTAAACCGTACTCATgtgaaatatgtaaaaaaatgtttaatagtcGGGACAATCGGAATGCCCATCGATTTGTGCACAGCGATAAGAAACCGTATGAATGTACAACATGTGGTGCTGGTTTTATGCGAAAACCACTACTCTTTGTGCATATGAAACAGGCAGCCCATTTTTCGGATGCTATCATTATTAACCAACCGCGAATCCAATCGATGGTGACTGCAACTAATCCAAAAGATGGTAAAAATGGAGTTGTATTTAAAACGGAAAAGATTGTTGTTGATAAAGATAATTCAAATGATGTTTTTACGGTGGAATATATTGAGGACGGAGAGCAAATGGACGACGGTGAAATAATTGACGGCGATCAAAATTTACTAGGTAACGAAATGGAATCAATACTTCCTGATGAAGAGGGACATGACGTGGAGGACGATGACGAAGATATGCCTGAAGATCATATTGTCGGTGAAGAGTTATCAGTTGAACATATTCTGGACAACTCCAATTTTTCCACCGAAACTATTGAACCGGGAACGGAAATTTTTATAACAGAAGAAGGACAGCTATACGAAACTGCTAATGGAACAATACACTATGTGAAAATCATAAATGATGCAGAGACGttgaagaataaaaaaaatgtatcaataaaattgcagtaa
Protein Sequence
MRRAKKTIDNNNTSGAVRINPEYDEAIEKIRSIDDSLEPPRLYFPGKTPINDLSPSFILSQILNRPLGSDTVHSDSLCQNCFKLCLEFEELEQRLVEIRLEFIRNFNNTAITYNLEPVELEDDEVEDDNLADENLVEEDDECDENDGDEEQTQEIVHDETREDEILEDPLEKITRHHQEILEQYETPEANEAEKETRVILLDNLPPSLVQDGHHSNTATYSIDATHFREEYLSEENHNMVEVVAESEDYVDLIVHETQMSHDENSYESGIVKDNSKSSENSQDSNRNHLFQIKVEQSDNSESAFSVPLNKTKGRKTNKTEKDAIVLSTSEIFTREGDSYVCQLCTDKSLIIYDGRTIGIHLKSIHDIKIYLCDICGQDFRKRSELTEHLDEHVSSTEDGFFTCDLCNREFNNLRLFRIHKRIHYTNSKSWPCTKCNKKYGSKNLLDEHMNMHTGKRPYKCGHCDKDFASKYTLSAHMKIHSDRPRPFNCRTCGKSFYSGQNLIQHEKTHTGLRPHVCEACDKSFSTQHNLEVHKIVHTGFKPFICRTCGKAFARRAEIKDHERTHTGEKPFKCDLCSASFAQRSNLQSHKRATHLDDKRYQCDICDRRFKRRRLLDYHKKATHTGERPFECRLCSATFVYPEHYKKHLRIHSGLKPYSCEICKKMFNSRDNRNAHRFVHSDKKPYECTTCGAGFMRKPLLFVHMKQAAHFSDAIIINQPRIQSMVTATNPKDGKNGVVFKTEKIVVDKDNSNDVFTVEYIEDGEQMDDGEIIDGDQNLLGNEMESILPDEEGHDVEDDDEDMPEDHIVGEELSVEHILDNSNFSTETIEPGTEIFITEEGQLYETANGTIHYVKIINDAETLKNKKNVSIKLQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01457769;
90% Identity
-
80% Identity
-