Ngue008786.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Nephrotoma guestfalica
Gene Symbol
Hr39
Assembly
GCA_963691935.1
Location
OY829913.1:121528003-121541726[+]

Transcription Factor Domain

TF Family
SF-like
Domain
zf-C4|SF-like
PFAM
AnimalTFDB
TF Group
Zinc-Coordinating Group
Description
The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 3 2 6.7e+04 -9.5 12.7 76 142 202 283 130 328 0.43
2 3 2.4e-09 7.9e-05 24.1 0.0 1 31 425 455 425 469 0.85
3 3 2.2e-78 7.3e-74 251.5 2.6 154 408 479 742 464 742 0.90

Sequence Information

Coding Sequence
ATGGCCACTACGGGTAGTAGCAATAGTAATGGTGGTAATACCACTGGCAATACAATTAGTGGTGTACCAACTTCGCGAGGCAACATATCCGTAACAAGTATTAATTGCAGTGATGATAAGGGCACACCAACCCAGATTACTCAGGCAACTGGACCAATAATGACAAATGGTGGGACTactcatttttttgaaaatggggGAATTCGAATATCTGTGCCAAAAATGGAGGAATCAGATGAATCTGATACTGAGTTGACAAATATTGAGAATAATTCAAGTAGTAATGTTGGTATGCGagaaaatcgtaataaaaatattccaaggCCGATGAGTTGGGAGGGTGAACTATCGGAAAACGAGGATAGTAATATGATTGTGGAAAATGGTGAGGCGAGTAATTTATCTGCAGCCACAATTCAAACAACATCAACAACTACGGTGACAACAAATGATGAACCAATCAATTTGCAGCAATTGCCAAAAGAATTTAAGCCTGAATTTTTAGACACCAATAGCTCATCGAATTTAATAGCAACATCATCATCTGCAAccacttatttaaatttaagtagtAAAAAATTTCCGGagtacattaatttaaaaaatgaatctggTGGTCATGATGTAATAAGTTCTCCGCTATTAGCTAGATCTAAATCAAATTTACTTCCAGCTAATCCAAGTCCGGATTCTGCAATACATTCTGTTTATACGCACAGTTCACCCTCCCAATCACCTTTAACATCCCGACATACTCCGTACACTCCGTCACTAAGTCGAAACAATAGTGATGCATCACATAGTAGCTGTTATTCATATAGTTCCGAATTTAGTCCAACACATTCCCCCATACAAAGTCGTCACTATTTATATGGACCAGCGTCGAATGCCGTACAAGCTGGTCTTACAAATTCACCGGCTCATCATTCGCTGCTGTACCGTCCGATGTTAGAAAGTGAGCAGAGTACATCTTCAAAATTTCTACAACCGAAAGAGGAGGGTGTGCTGGAGGGTGAAGCAATACCGTCGCCCGGAATATCAAGACAGCAACTAATAAATAGTCCGTGCCCAATATGTGGTGATAAAATATCAGGCTTCCATTATGGTATTTTTTCATGTGAATCGTGCAAGGGATTTTTTAAGCGCACCgtgcaaaatagaaaaaattatgtttgtttacGAGGGGCAGCATGCCCTGTCACAATAGCAACACGGAAAAAATGTCCGGCTTGCCGGTTTGAAAAGTGTCTGCAAAAAGGAATGAAATTAGAAGCAATTCGAGAGGATCGAACCAGAGGTGGTCGATCCACTTACCAATGTTCGTATACATTACCCGGATCAATGCTTAGTCCATCGGTTAGTTCCGAATCATcagctaatttttattatagtcaAAGACTTTCAACAAATGGATTATTAAAAGTTGAAACGCCTGAATCGAGTTCAAGTACATCGACATTTAATAGTAATGTTAAGCTAGAAATCCCACCACTTTTGCAAGATATCATGGATGTTGAACATTTGTGGCATTACAATGACGCTGAATTATCTCGTTTAAATCAGCCAGCATCATCAAATCAATCGACAAACGTTGAATCGAACCCTCTACTAGCTAGCGCTGGATTATCGAAAAGTGATAATCCTgatttaattgcaaatttatgTAATGTAGCCGATCATCGTCTTTATAAAATAGTGAAATGGTGTAAAAGTTTACCTTTATTTAAGAATATATCGATTGATGATCAAATATGTTTGCTTATTAATTCATGGtgtgaattattattgttttcttgttgttttcgATCAATGTCCACTCCTGGTGAGATTAGAATATCTTTAGGCAAATCGATAACATTACAGCAGGCAAAATCAAGTGGTTTACagtCATGTATTGAACGAATGCTTAATTTAACGGAGCATTTAAGACGGTTAAAGGTAGATAGGTATGAGTATGTTGCGATGAAAGTTATAGTATTATTACAGTCAGACACGTCTGAATTAAAAGAGCCTGAAAAGGTGCGGACAAGTCAGGAAAAGGCATTACAAGCATTACAGGCATATACATTATCACATTATCCAGATACGCCTGCTAAATTTGGCGAACTATTATTGCGGATACCGGAATTACAGCGGACATGCCAGgttgGAAAAGAAATgctaattattaaatcaaaggAAGGCGAAGAATTTAATCTACTGATGGAATTATTACGAGGTGAACACTAG
Protein Sequence
MATTGSSNSNGGNTTGNTISGVPTSRGNISVTSINCSDDKGTPTQITQATGPIMTNGGTTHFFENGGIRISVPKMEESDESDTELTNIENNSSSNVGMRENRNKNIPRPMSWEGELSENEDSNMIVENGEASNLSAATIQTTSTTTVTTNDEPINLQQLPKEFKPEFLDTNSSSNLIATSSSATTYLNLSSKKFPEYINLKNESGGHDVISSPLLARSKSNLLPANPSPDSAIHSVYTHSSPSQSPLTSRHTPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQSRHYLYGPASNAVQAGLTNSPAHHSLLYRPMLESEQSTSSKFLQPKEEGVLEGEAIPSPGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCLRGAACPVTIATRKKCPACRFEKCLQKGMKLEAIREDRTRGGRSTYQCSYTLPGSMLSPSVSSESSANFYYSQRLSTNGLLKVETPESSSSTSTFNSNVKLEIPPLLQDIMDVEHLWHYNDAELSRLNQPASSNQSTNVESNPLLASAGLSKSDNPDLIANLCNVADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSMSTPGEIRISLGKSITLQQAKSSGLQSCIERMLNLTEHLRRLKVDRYEYVAMKVIVLLQSDTSELKEPEKVRTSQEKALQALQAYTLSHYPDTPAKFGELLLRIPELQRTCQVGKEMLIIKSKEGEEFNLLMELLRGEH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01458497;
90% Identity
iTF_01458497;
80% Identity
iTF_01054421;